Drug Metabolism and Pharmacokinetics最新文献_第8页

Drug-drug interaction between trastuzumab emtansine (T-DM1) and orally administered tacrolimus in a patient and in rats 曲妥珠单抗emtansine （T-DM1）和口服他克莫司在患者和大鼠中的药物相互作用

IF 2.7 4区医学

Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101486

Tomohiro Nakamura , Moeko Shimada , Makiko Takabayashi , Arimi Fujita , Takahiro Kawakami , Hiroyuki Maruyama , Hirofumi Terakawa , Takahiro Ishimoto , Tsutomu Shimada , Toshihiro Miyamoto , Yoshimichi Sai

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A tale of preclinical insights into bile salt homeostasis disruption in DILI DILI患者胆盐稳态紊乱的临床前研究

IF 2.7 4区医学

Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101108

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Effects of mefenamic acid on the conjugative metabolism of indole and p-cresol in relation to cellular necrosis in a metabolically competent human hepatoma cell line 甲氧胺酸对吲哚和对甲酚共轭代谢的影响与代谢能力强的人肝癌细胞系细胞坏死有关

IF 2.7 4区医学

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Foreword – Disclaimer 前言-免责声明

IF 2.7 4区医学

Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/S1347-4367(25)00444-6

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Development of a strategy to prevent cisplatin-induced kidney injury by targeting mate-type transporters 通过靶向配偶型转运蛋白来预防顺铂所致肾损伤策略的发展

IF 2.7 4区医学

Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101129

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Role of intracellular SLC46A3 in the cytosolic exposure and pharmacological effect of the payload of trastuzumab emtansine (ADC) 细胞内SLC46A3在曲妥珠单抗emtansine （ADC）有效负荷的胞质暴露和药理作用中的作用

IF 2.7 4区医学

Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101095

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IF 2.7 4区医学

Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101090

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Review of finalized ICH M12 guideline on drug interaction studies 对ICH M12药物相互作用研究指南定稿的审查

IF 2.7 4区医学

Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101079

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IF 2.7 4区医学

Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101117

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Development of dissolution evaluation system for drug absorption (V): Additional intestinal absorption module of in vitro 3D gastric emptying mmodel for orally disintegrating tablet 药物吸收溶出度评价系统的开发(V)：口腔崩解片体外三维胃排空模型的附加肠吸收模块

IF 2.7 4区医学

Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101140

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