Caroline M Wilkowski, Elizabeth M Rao, Alexander K Maytin, Maira Bhatty, Roberta L Klatzky, Salim Hayek, Melinda Lawrence, Jeffrey Janata, Bryan T Carroll
{"title":"Comparison of Patient Reported Sensory Hypersensitivity in Mohs and Interventional Pain Patients.","authors":"Caroline M Wilkowski, Elizabeth M Rao, Alexander K Maytin, Maira Bhatty, Roberta L Klatzky, Salim Hayek, Melinda Lawrence, Jeffrey Janata, Bryan T Carroll","doi":"10.1097/DSS.0000000000004464","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004464","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142496976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baraa A Hijaz, Grant J Riew, Catherine Pisano, Emily S Ruiz, Vinod E Nambudiri
{"title":"Point-of-Care Ultrasound's Implications for Dermatology: A Focus on POCUS.","authors":"Baraa A Hijaz, Grant J Riew, Catherine Pisano, Emily S Ruiz, Vinod E Nambudiri","doi":"10.1097/DSS.0000000000004469","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004469","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142496985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabrina G Fabi, Jennifer Htd Le, Inna Prygova, Daniel Bråsäter
{"title":"Midface Projection Using Biostimulatory Poly-l-Lactic Acid Injectable Implant: A Subgroup Analysis of the Cheek Wrinkle Trial.","authors":"Sabrina G Fabi, Jennifer Htd Le, Inna Prygova, Daniel Bråsäter","doi":"10.1097/DSS.0000000000004434","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004434","url":null,"abstract":"<p><strong>Background: </strong>Correction of cheek wrinkles using poly-l-lactic acid (PLLA-SCA) was demonstrated in a 12-month study.</p><p><strong>Objective: </strong>This analysis assessed change from baseline in lifting effect of PLLA-SCA using a 3D camera to provide additional quantified data.</p><p><strong>Methods: </strong>Subjects received PLLA-SCA (reconstituted in 8 mL of sterile water + 1 mL of 2% lidocaine) in both cheeks or no treatment (control). Assessments included the Galderma Cheek Wrinkle Scale (GCWS), aesthetic improvement, and 3D photography. In subjects with severe GCWS at baseline, Canfield software analyzed 3D images for change from baseline in midface volume projection and volume change of both cheeks at Month 9.</p><p><strong>Results: </strong>The primary study showed a statistically significant higher at-rest GCWS responder rate at Month 12 for PLLA-SCA, 71.6%, versus control, 26.1% (p < .0001). In this Month 9 analysis, mean midface volume projection demonstrated a positive volume shift for PLLA-SCA (left: 0.45 mm; right: 0.34 mm; n = 46) versus control (left: 0.25 mm; right: -0.01 mm; n = 21). Midface volume and max projection changes for PLLA-SCA were +4.88 mL/+1.62 mm (left), +2.84 mL/+1.12 mm (right) versus +0.26 mL/+0.34 mm (left), +0.68 mL/+0.37 mm (right) for control.</p><p><strong>Conclusion: </strong>Poly-l-lactic acid-treatment of subjects with severe GCWS had a clinically meaningful lifting effect in both cheeks (positive volume shift, positive volume change, and max projection) in the midface.</p><p><strong>Clinical trial registry number: </strong>NCT04124692.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142496983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joseph Gofman, Colin Burnette, Daniel L Fischer, Sourab Choudhury
{"title":"Squamous Cell Carcinoma Emerging From a Decades-Old Condyloma Acuminatum: A Rare Malignant Transformation of Low-Risk HPV.","authors":"Joseph Gofman, Colin Burnette, Daniel L Fischer, Sourab Choudhury","doi":"10.1097/DSS.0000000000004459","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004459","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142460345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Woolhiser, Michelle Sobotka, Colin Burnette, Lauren Gawey, Cory A Dunnick
{"title":"Topical Therapies for Periorbital Dyschromia: A 30-Year Review of the Literature.","authors":"Emily Woolhiser, Michelle Sobotka, Colin Burnette, Lauren Gawey, Cory A Dunnick","doi":"10.1097/DSS.0000000000004429","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004429","url":null,"abstract":"<p><strong>Background: </strong>Periorbital dyschromia (POD) is a prevalent dermatologic problem with multifactorial etiology, making treatment outcomes inconsistent and unclear.</p><p><strong>Objective: </strong>To evaluate and compose a comprehensive review of topical ingredients proven to be effective in the treatment of POD.</p><p><strong>Materials and methods: </strong>Scopus, PubMed, and OVID databases were searched in a span of 30 years through December 31, 2023, to identify articles with original findings of topical therapies for the treatment of POD. Findings of interest were objectively and subjectively measured regarding pigmentation, skin texture, aesthetic improvement, elasticity, hydration, and eye-bag volume.</p><p><strong>Results: </strong>The database searches yielded 339 unique studies. After screening and review, 22 studies were included totaling 13 nonrandomized control trials, 7 randomized clinical trials, 1 retrospective case series, and 1 prospective single-arm study. Studies included all reported statistically significant results with topical therapies inclusive of acids, bark extract, bicyclic monoterpene diols, caffeine, combo ingredient serums, ethyl ximenynate, gentiopicroside, glycosaminoglycans, growth factors, topical PRP, and vitamins.</p><p><strong>Conclusion: </strong>The findings of this review suggest that topical therapies can be effective in the treatment of POD. Future trials should focus on delineating specific etiology of POD and evaluation of therapies specific to their cause.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142460430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kawaiola C Aoki, Danielle Lazzara, Gregory Bartos, Eduardo Weiss, Eli R Saleeby
{"title":"Surgical Margins of Nonmelanoma Skin Cancers in Mohs Surgery: Dermoscopy Versus Naked Eye.","authors":"Kawaiola C Aoki, Danielle Lazzara, Gregory Bartos, Eduardo Weiss, Eli R Saleeby","doi":"10.1097/DSS.0000000000004455","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004455","url":null,"abstract":"<p><strong>Background: </strong>Mohs micrographic surgery (MMS) offers high cure rates for nonmelanoma skin cancer (NMSC) but relies on precise margin assessment, traditionally initiated by the naked eye. Dermoscopy has emerged as a potential tool to improve margin delineation.</p><p><strong>Objective: </strong>To compare the efficacy of dermoscopic versus naked eye evaluation in marking initial MMS margins for NMSC.</p><p><strong>Methods: </strong>A multicenter, prospective study on patients with NMSC undergoing MMS was conducted. Patients were randomized into dermoscopy and naked eye groups. Statistical analysis was performed using statistical package for social sciences.</p><p><strong>Results: </strong>A total of 127 patients were enrolled, with 63 in the naked eye group and 64 in the dermoscopy group. No significant differences in age, sex distribution, or histological subtype were found. The average number of MMS stages and accuracy of initial margins were comparable between groups.</p><p><strong>Discussion: </strong>Despite its potential, the authors' study found no significant reduction in total MMS stages using dermoscopy. Novel imaging modalities or standardized dermoscopic criteria should be explored to enhance margin assessment accuracy and improve outcomes in NMSC treatment.</p><p><strong>Conclusion: </strong>Dermoscopic evaluation of presurgical margins does not effectively assess lateral/deep margins nor contribute to a reduction in total MMS stages. Improving the authors' understanding of presurgical margin assessment techniques can lead to better treatment outcomes for NMSC.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142460347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yelena Dokic, Ikue Shimizu, Jennifer Song Ranario, Jose A Cervantes
{"title":"Reconstruction of a Double Defect on the Temple and Forehead.","authors":"Yelena Dokic, Ikue Shimizu, Jennifer Song Ranario, Jose A Cervantes","doi":"10.1097/DSS.0000000000004448","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004448","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142460344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Cost of a Melanoma Diagnosis: An Analysis of Online Crowdfunding for Medical Expenses Related to Melanoma.","authors":"Afua Ofori-Darko, Devin Barzallo, Nikole Guzman Villegas, Ashley Perez, Katherine DiSano","doi":"10.1097/DSS.0000000000004461","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004461","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142460348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James Feng, Payal Shah, Rachael Chacko, Matthew J Davis, Matthew LeBoeuf
{"title":"Clinical Risk Factors of Subclinical Spread in Melanoma in Situ and Invasive Melanoma.","authors":"James Feng, Payal Shah, Rachael Chacko, Matthew J Davis, Matthew LeBoeuf","doi":"10.1097/DSS.0000000000004456","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004456","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142460341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofia M Perez, Mounika Vattigunta, Colin Kelly, Ariel Eber
{"title":"Low-Level Laser and LED Therapy in Alopecia: A Systematic Review and Meta-Analysis.","authors":"Sofia M Perez, Mounika Vattigunta, Colin Kelly, Ariel Eber","doi":"10.1097/DSS.0000000000004442","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004442","url":null,"abstract":"<p><strong>Background: </strong>Low-level laser/LED therapy (LLLT) has been described as a treatment option for alopecia, but no study has comprehensively reviewed its efficacy in multiple alopecia types.</p><p><strong>Objective: </strong>To review and evaluate LLLT for various alopecia types.</p><p><strong>Materials and methods: </strong>A systematic search of PubMed/MEDLINE, Embase, and CENTRAL was conducted to identify studies assessing the effect of LLLT on patients diagnosed with alopecia. Prespecified outcome measure was the change in hair density. Meta-analysis was performed to calculate the standardized mean difference in hair density before and after LLLT compared with placebo.</p><p><strong>Results: </strong>Thirty-eight studies were included that described 3,098 patients with androgenetic alopecia (2,930/3,098), scarring alopecia (49/3,098), alopecia areata (50/3,098), telogen effluvium (17/3,098), and chemotherapy-induced alopecia (32/3,098). The mean change in hair density increased significantly in androgenetic alopecia patients after LLLT for 4 to 26 weeks compared with placebo (<20 weeks: SMD = 1.14; 95% CI [0.51-1.78]; p = .000; I2 = 88.26%; >20 weeks: SMD = 1.44; 95% CI [0.97-1.91]; p = .000; I2 = 80.81%). Change in hair density was reported in 5 studies evaluating other alopecia types; however, statistical information was insufficient for meta-analysis.</p><p><strong>Conclusion: </strong>LLLT is a promising treatment option for patients with androgenetic alopecia, but future studies are needed to better understand its efficacy in other alopecia types.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142460343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}