Dermatologic SurgeryPub Date : 2024-12-01Epub Date: 2024-08-23DOI: 10.1097/DSS.0000000000004375
Harrison Zhu, Daniel J Lewis, Dylan Haynes, Leo L Wang
{"title":"Engineered Skin Substitutes in Dermatologic Surgery: A Systematic Review.","authors":"Harrison Zhu, Daniel J Lewis, Dylan Haynes, Leo L Wang","doi":"10.1097/DSS.0000000000004375","DOIUrl":"10.1097/DSS.0000000000004375","url":null,"abstract":"<p><strong>Background: </strong>Artificial skin substitutes are a flexible alternative to autografting in Mohs micrographic surgery (MMS), but the characteristics and clinical outcomes of skin substitutes are not well defined.</p><p><strong>Objective: </strong>Summarize clinical data of skin substitutes in MMS for cutaneous malignancy.</p><p><strong>Methods: </strong>A MEDLINE/Embase/Web of Science search was conducted. Articles with original data on outcomes after skin substitute use in MMS for cutaneous malignancy were included. Articles not in English or without original data were excluded. Bias was assessed using the Oxford CEBM Levels of Evidence Table. Outcomes were synthesized using weighted averages. This study was prospectively registered in PROSPERO.</p><p><strong>Results: </strong>Of 1,007 articles, 40 met eligibility for inclusion. In total, 898 patients who underwent MMS and received a skin substitute were included. Xenografts were most commonly used ( n = 613). Semi-synthetic grafts (∼$<1/cm 2 ) and xenografts (∼$10/cm 2 ) are most affordable. Overall, outcomes were excellent for all skin substitutes, with a small proportion of patients experiencing correctable complications.</p><p><strong>Conclusion: </strong>Skin substitutes are highly effective in MMS, with enormous potential. While the data demonstrate positive outcomes, they predominately draw from small, retrospective studies or case reports. There is also a scarcity of data comparing skin substitutes with each other or controls. Prospective studies are recommended.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":"1175-1181"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatologic SurgeryPub Date : 2024-12-01Epub Date: 2024-10-28DOI: 10.1097/DSS.0000000000004478
Alexandra Mathis, Alex Harrison, Chris Harmon
{"title":"Atypical Presentation of Cutaneous Malignancies in Darker Skin.","authors":"Alexandra Mathis, Alex Harrison, Chris Harmon","doi":"10.1097/DSS.0000000000004478","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004478","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":"50 12S","pages":"S214-S215"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142726847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatologic SurgeryPub Date : 2024-12-01Epub Date: 2024-06-28DOI: 10.1097/DSS.0000000000004304
Olivia S Jew, Jonathan Dutton, Jonathan L Cook
{"title":"Unexpected Facial Nerve Injury During Nasal Reconstruction.","authors":"Olivia S Jew, Jonathan Dutton, Jonathan L Cook","doi":"10.1097/DSS.0000000000004304","DOIUrl":"10.1097/DSS.0000000000004304","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":"1216-1218"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatologic SurgeryPub Date : 2024-12-01Epub Date: 2024-09-30DOI: 10.1097/DSS.0000000000004400
Marine Minasyan, Sara Hogan, Karan Lal
{"title":"Oral Tranexamic Acid for Prevention and Treatment of Postinflammatory Hyperpigmentation.","authors":"Marine Minasyan, Sara Hogan, Karan Lal","doi":"10.1097/DSS.0000000000004400","DOIUrl":"10.1097/DSS.0000000000004400","url":null,"abstract":"<p><strong>Background: </strong>Postinflammatory hyperpigmentation (PIH) is a skin disorder characterized by hyperpigmentation resulting from heightened inflammation and/or damage to the basement membrane, melanocytes, and keratinocytes, leading to abnormal and excessive pigment deposition. Oral tranexamic acid (TXA), originally used as an antifibrinolytic for managing excessive bleeding, has garnered attention for its demonstrated safety and efficacy in treating melasma. There is a growing body of evidence regarding the use of TXA in the treatment of PIH.</p><p><strong>Objective: </strong>To review the mechanism of action of oral TXA in treating PIH and examine the use of oral TXA in preventing and/or treating PIH associated with laser-based and light-based treatments in individuals with skin color.</p><p><strong>Methods: </strong>Review of relevant articles from 2000 to present found in the Cochrane Library, PubMed, Embase, and Google Scholar, regarding the use of oral TXA in the treatment of PIH.</p><p><strong>Results: </strong>Studies reviewed investigated the efficacy of oral tranexamic acid (TXA) in treating postinflammatory hyperpigmentation (PIH) and use in preventing PIH when used in conjunction with other treatments. All studies demonstrated significant improvement in PIH without significant adverse effects and side effects.</p><p><strong>Conclusion: </strong>Oral tranexamic acid is emerging as a safe and effective treatment in the prevention and treatment of postinflammatory hyperpigmentation.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":"S219-S224"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatologic SurgeryPub Date : 2024-12-01Epub Date: 2024-06-26DOI: 10.1097/DSS.0000000000004306
Laura van de Borne, Mathilde Costantini, Florence Dehavay, Bertrand Richert
{"title":"Onychomatricomas: Assessing Surgical Outcomes.","authors":"Laura van de Borne, Mathilde Costantini, Florence Dehavay, Bertrand Richert","doi":"10.1097/DSS.0000000000004306","DOIUrl":"10.1097/DSS.0000000000004306","url":null,"abstract":"<p><strong>Background: </strong>Onychomatricoma (OM) is a rare benign tumor of the nail matrix. Treatment is surgical, but data are currently limited.</p><p><strong>Objective: </strong>To review all cases of OM operated in their department and to assess the link between the location on the nail plate, the thickness and width of the lesion, and the postoperative outcomes.</p><p><strong>Materials and methods: </strong>Records of 62 patients were retrieved from their department's database over a 25-year period (1998-2023).</p><p><strong>Results: </strong>Of the 62 patients, 41 were eligible. In total, 58% of OM occupied a width of a quarter of the nail plate, 51% had a plate thinner than 3 mm, and 51% were laterally located. Of the 41 patients included, 29 had a tangential excision and 12 underwent lateral longitudinal excision. Among the tangential excision group, 71% had normal nail regrowth. Onychomatricoma thicker than 3 mm and involving the total nail plate width had a sequelae in 60% of cases.</p><p><strong>Conclusion: </strong>Tangential excision of onychomatricomas allows a normal nail regrowth in 71% of cases. The risk of sequelae increases for tumors thicker than 3 mm and involving the total nail plate width. Medial or lateral location seems to have no influence.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":"1109-1113"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141455902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatologic SurgeryPub Date : 2024-12-01Epub Date: 2024-07-30DOI: 10.1097/DSS.0000000000004308
Amy Forman Taub, Valerie Dawn Callender
{"title":"Jowl Improvement With Injectable Fillers: Jawline Injections Alone Versus Jawline and Cheek Injections.","authors":"Amy Forman Taub, Valerie Dawn Callender","doi":"10.1097/DSS.0000000000004308","DOIUrl":"10.1097/DSS.0000000000004308","url":null,"abstract":"<p><strong>Background: </strong>Jowling is a common aesthetic complaint in aging individuals.</p><p><strong>Objective: </strong>Injectable filler placed at the lateral jawline will improve the appearance of jowls, as defined by the Merz Aesthetic Jawline Grading Scale (MAJGS). This improvement will be independent of concomitant injection of filler into the lateral cheek.</p><p><strong>Methods: </strong>Fifteen female subjects with grade 2 to 3 jowls on a scale of 0 to 4 were enrolled to receive either VYC-20L in the mandibular angle/ramus (Group 1) or the mandibular angle/ramus and lateral cheek (Group 2). The subjects were evaluated by a blinded cosmetic dermatologist and themselves at 4 weeks after the last injection.</p><p><strong>Results: </strong>A statistically significant improvement was noted in Group 1 by all blinded reviewers and subjects. Group 2 did not reach statistical significance as evaluated by the blinded dermatologist although did by the subject's rating. The average amount of filler injected per subject was 3.36 mL for group 1 and 8.38 mL for group 2. A novel adverse event was tenderness when chewing lasting for 2 to 3 days.</p><p><strong>Conclusion: </strong>Injection of VYC-20L showed statistical improvement in a validated jowl scale when injected at the angle of the mandible and the mandibular ramus, independent of concomitant lateral cheek injections.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":"1149-1154"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatologic SurgeryPub Date : 2024-12-01Epub Date: 2024-03-13DOI: 10.1097/DSS.0000000000004161
Ariel Finberg, Ravi S Krishnan
{"title":"Reconstruction of a Large Glabellar Defect.","authors":"Ariel Finberg, Ravi S Krishnan","doi":"10.1097/DSS.0000000000004161","DOIUrl":"10.1097/DSS.0000000000004161","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":"1191-1193"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140109614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dermatologic SurgeryPub Date : 2024-12-01Epub Date: 2024-09-05DOI: 10.1097/DSS.0000000000004395
Tae Hwan Park, Arianne Shadi Kourosh
{"title":"Commentary on \"Benefits of Punch Excision Followed by Immediate Cryotherapy for Recalcitrant Keloids: A Comparison With Core Excision\".","authors":"Tae Hwan Park, Arianne Shadi Kourosh","doi":"10.1097/DSS.0000000000004395","DOIUrl":"10.1097/DSS.0000000000004395","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":"1229-1230"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}