{"title":"Nanofat Transfer to the Face: How We Do It.","authors":"Hunter Gray, Lauren Moy, Solomiya Grushchak, Sahitya Reddy","doi":"10.1097/DSS.0000000000005382","DOIUrl":"https://doi.org/10.1097/DSS.0000000000005382","url":null,"abstract":"<p><strong>Background: </strong>Nanofat transfer is a mechanically emulsified, cell-based autologous fat product used to improve facial skin quality through the paracrine activity of adipose-derived stem cells and growth factors.</p><p><strong>Objective: </strong>To provide dermatologic surgeons with a practical, step-by-step review of nanofat harvesting, processing, emulsification, and delivery technique for facial rejuvenation, along with a summary of the supporting clinical evidence and safety profile.</p><p><strong>Materials and methods: </strong>This review describes established supplies, donor-site harvesting technique, washing and purification options (gravity decantation, cotton gauze rolling, centrifugation, and closed washing/filtration systems), mechanical emulsification, and dermal delivery technique, synthesized from the published nanofat literature.</p><p><strong>Results: </strong>Across the reviewed literature, nanofat improves dermal thickness, collagen density, hydration, and fine rhytides, with an established role in scar treatment and emerging applications in androgenetic alopecia, wound healing, and pigmentary conditions. Reported adverse events are mild and self-limited, and the technique carries a favorable overall safety profile.</p><p><strong>Conclusion: </strong>Nanofat transfer is a simple, in-office, autologous technique that offers dermatologic surgeons a versatile option for facial skin rejuvenation when attention is paid to gentle harvesting, appropriate processing, thorough emulsification, and precise delivery.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are \"Pressure Dressings\" Truly Applying Pressure? A Pilot Study in Mohs Surgery.","authors":"Caitlin Perez-Stable, Yelena Dokic, Ikue Shimizu","doi":"10.1097/DSS.0000000000005401","DOIUrl":"https://doi.org/10.1097/DSS.0000000000005401","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Areas of High Risk and High Reward: Temple, Nose, Lip, and Jawline Filler.","authors":"Rebecca Kazin, Vince Bertucci","doi":"10.1097/DSS.0000000000005394","DOIUrl":"https://doi.org/10.1097/DSS.0000000000005394","url":null,"abstract":"<p><strong>Background: </strong>Soft tissue filler treatment of the temple, nose, lip, and jawline can produce substantial aesthetic improvement but contain risks ranging from contour irregularities to tissue necrosis, vision loss, and embolic events.</p><p><strong>Objective: </strong>Review anatomic considerations, product selection, injection techniques, clinical benefits, and complication-mitigation strategies relevant to filler treatment of high-impact, high-risk facial regions.</p><p><strong>Materials and methods: </strong>Anatomic, clinical trial, consensus, imaging, and complication-management literature regarding filler augmentation of the temple, jawline, lip, and nose was reviewed and synthesized.</p><p><strong>Results: </strong>Hyaluronic acid fillers offer immediate correction and reversibility and remain central to treatment of the temple, jawline, lip, and nose. Safer treatment depends on knowledge of region-specific vascular anatomy, conservative volumes, slow low-pressure injection, small aliquots, and appropriate depth. Product selection should be individualized according to multiple factors such as treatment plane, skin thickness, tissue mobility, desired projection, and filler rheology. Cannulas may reduce vascular occlusion risk compared with needles, although needles retain value for precise product placement.</p><p><strong>Conclusion: </strong>Filler treatment of the temple, nose, lip, and jawline can be highly rewarding when product properties and injection technique are matched to anatomy and patient goals. Prevention, early recognition of vascular compromise, and access to complication-management protocols are essential.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response and Correction Statements to the Letter From Dr. Shao Hui's Team: The Explanation on the Total Dose and the Preparation Method of Polidocanol Sclerotherapy for the Treatment of Axillary Osmidrosis.","authors":"Yantao Cai, Chenfang Zhu","doi":"10.1097/DSS.0000000000005393","DOIUrl":"10.1097/DSS.0000000000005393","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myths and Misconceptions in Botulinum Toxin Practice: An Evidence-Based Review.","authors":"Payvand Kamrani, Sue Ellen Cox, Deirdre Hooper","doi":"10.1097/DSS.0000000000005356","DOIUrl":"https://doi.org/10.1097/DSS.0000000000005356","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tejas P Joshi, Caitlin Perez-Stable, Sreeya Reddy, Ida F Orengo
{"title":"Risk Factors for Positive Margins After Pleomorphic Dermal Sarcoma Excision and Prognostic Impact of Margin Positivity: A National Cancer Database Analysis.","authors":"Tejas P Joshi, Caitlin Perez-Stable, Sreeya Reddy, Ida F Orengo","doi":"10.1097/DSS.0000000000005413","DOIUrl":"https://doi.org/10.1097/DSS.0000000000005413","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chenan A Huang, Summer Wong, Jaime M Lane, Ainsley J Ruley, Matthew L Hrin, Christine S Ahn, Steven R Feldman
{"title":"Practice Preferences of Mohs Histology Technicians: A Web-Based Survey.","authors":"Chenan A Huang, Summer Wong, Jaime M Lane, Ainsley J Ruley, Matthew L Hrin, Christine S Ahn, Steven R Feldman","doi":"10.1097/DSS.0000000000005391","DOIUrl":"https://doi.org/10.1097/DSS.0000000000005391","url":null,"abstract":"<p><strong>Background: </strong>Frozen section processing (FSP) enables real-time histologic margin assessment during Mohs micrographic surgery (MMS). FSP techniques are variable, and processing speeds are poorly characterized.</p><p><strong>Objective: </strong>To identify rate-limiting steps and technique variations in FSP.</p><p><strong>Materials and methods: </strong>A web-based survey was distributed to MMS and dermatopathology technicians assessing slow steps, challenging tissue types, technique variability, prevalence techniques, and practice preferences.</p><p><strong>Results: </strong>A 5-point Likert rating of 3 to 5 was defined as slow. Response rates above 50% categorized the step as slow, and response rates below 50% categorized the step as fast. Slow steps included flattening/debulking (78%), sectioning (58%), staining (58%), and embedding (53%). Fast steps included aligning the cryotome (40%), acquiring the sample (22%), mounting to a chuck (18%), mounting to a slide (16%), inking (9%), and adding a coverslip (8%). Difficult-to-section tissues were adipose (65%), cartilage (46%), and thin tissue (39%). Variable steps include flattening/debulking (36%) and embedding (36%). The most common preparation method was the glass slide technique (63%), then the heat extractor (28%), and finally well bars (9%). Most did not use an embedding device (59%).</p><p><strong>Conclusion: </strong>Flattening/debulking, embedding, sectioning, and staining can benefit from increased processing speed. Simplifying adipose, cartilage, and thin tissue processing can reduce the burden on technicians.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara D Ragi, Megan Hoang, Hayley S Goldbach, Tiffany J Libby
{"title":"Association Between Time to Definitive Surgery and Survival Outcomes in Amelanotic Melanoma: A Population-Based Cohort Study.","authors":"Sara D Ragi, Megan Hoang, Hayley S Goldbach, Tiffany J Libby","doi":"10.1097/DSS.0000000000005388","DOIUrl":"https://doi.org/10.1097/DSS.0000000000005388","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seetha Aribindi, Nitika V Tripathi, Jasmine Gulati, Michael J Reilly
{"title":"Complications, Treatments, and Outcomes of Self-Injecting Substances Into the Body.","authors":"Seetha Aribindi, Nitika V Tripathi, Jasmine Gulati, Michael J Reilly","doi":"10.1097/DSS.0000000000005371","DOIUrl":"https://doi.org/10.1097/DSS.0000000000005371","url":null,"abstract":"","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Payvand Kamrani, Sue Ellen Cox, Katie Beleznay, Shannon Humphrey
{"title":"From Bruising to Blindness: A Practical Guide to Identifying and Managing Hyaluronic Acid Filler Complications.","authors":"Payvand Kamrani, Sue Ellen Cox, Katie Beleznay, Shannon Humphrey","doi":"10.1097/DSS.0000000000005380","DOIUrl":"https://doi.org/10.1097/DSS.0000000000005380","url":null,"abstract":"<p><strong>Purpose: </strong>To provide a comprehensive, evidence-based review of the complications associated with hyaluronic acid (HA) dermal fillers and to offer practical guidance for their identification, prevention, and management.</p><p><strong>Design: </strong>Narrative review of the peer-reviewed literature, consensus guidelines, and postmarket surveillance data addressing the classification, pathophysiology, prevention, and treatment of HA filler complications.</p><p><strong>Findings: </strong>Hyaluronic acid fillers carry a favorable safety profile, with severe complications reported in fewer than 0.01% of injection sites. Complications are classified by onset. Early-onset events include ecchymosis, injection-site and hypersensitivity reactions, product displacement, and vascular occlusion. Late-onset events include biofilm-associated infection, delayed inflammatory nodules, granulomas, and hyperpigmentation. Vascular occlusion is the most feared complication and may progress to skin necrosis, vision loss, or stroke; prompt recognition and high-dose hyaluronidase, increasingly aided by ultrasound guidance, are central to management. Prevention rests on sound anatomic knowledge, appropriate product selection, and careful injection technique, while treatment is tailored to the specific complication.</p><p><strong>Summary: </strong>As filler use continues to expand, clinicians must be prepared to recognize, prevent, and manage the full spectrum of complications. This review consolidates current evidence into a practical framework intended to support safe practice and optimal patient outcomes.</p>","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149147926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}