Dermatologic Surgery最新文献_第8页

Effects and Safety of Botulinum Toxin Injection in Treatment of Androgenetic Alopecia: A Meta-analysis and Systematic Review. 注射肉毒毒素治疗雄激素性脱发的疗效和安全性：荟萃分析和系统评价。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-01-22 DOI: 10.1097/DSS.0000000000004557

Fengrui Cheng, Xingrui Cai, Ying Zhang, Jingping Wu, Sisi Yin

{"title":"Effects and Safety of Botulinum Toxin Injection in Treatment of Androgenetic Alopecia: A Meta-analysis and Systematic Review.","authors":"Fengrui Cheng, Xingrui Cai, Ying Zhang, Jingping Wu, Sisi Yin","doi":"10.1097/DSS.0000000000004557","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004557","url":null,"abstract":"Background: Androgenetic alopecia (AGA) is a prevalent condition that significantly affects the psychosocial well-being of many individuals, and its treatment remains a clinical challenge. Botulinum toxin (BTX) injections have been reported to have a therapeutic effect on AGA. Although several studies have explored the efficacy and safety of this novel treatment, most are clinical studies with small sample sizes.Objective: To evaluate the efficacy and safety of BTX injections in the treatment of AGA through a meta-analysis and systematic review.Methods: A comprehensive literature search was conducted using PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, ScienceDirect, Springer, and Web of Science to identify studies investigating the use of BTX in the treatment of AGA. The primary outcome was hair count.Results: Eight studies were included in the systematic review. The pooled data demonstrated a statistically significant increase in hair count in patients treated with BTX compared with the control group (standardized mean difference = 1.02; 95% confidence interval, 0.30-1.74, p < .05).Conclusion: Injectable BTX seems to be a promising treatment for AGA, showing significant efficacy and good safety.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Research Waste in Phase III/IV Randomized Controlled Trials of Botulinum Toxin Type A. A型肉毒毒素III/IV期随机对照试验研究废弃物分析

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-01-22 DOI: 10.1097/DSS.0000000000004552

Hongrui Chen, Shih-Jen Chang, Yuanyang Zheng, Yanchun Zhou, Bin Sun, Chen Hua, Xiaoxi Lin

{"title":"Analysis of Research Waste in Phase III/IV Randomized Controlled Trials of Botulinum Toxin Type A.","authors":"Hongrui Chen, Shih-Jen Chang, Yuanyang Zheng, Yanchun Zhou, Bin Sun, Chen Hua, Xiaoxi Lin","doi":"10.1097/DSS.0000000000004552","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004552","url":null,"abstract":"Background: The application of randomized controlled trials (RCTs) outcomes of botulinum toxin type A (BoNT-A) to actual patient care faces a significant hurdle due to research waste (RW). This includes the results of RCTs that have not been published even 4 years after completion and those with insufficiently reported outcomes and design flaws. The prevalence of RW within BoNT-A-associated RCTs remains uncertain.Objective: To assess the extent of RW (non-publication, insufficient reporting, and design flaws) in BoNT-A RCTs.Methods: The authors searched the ClinicalTrials using 'botulinum toxin type A' as the keyword. They verified the publication status through PubMed and Scopus searches. The adequacy of reporting was assessed using the Consolidated Standards of Reporting Trials checklist, while design limitations were evaluated based on the risk of bias and systematic reviews.Results: Two hundred twenty-eight RCTs met the inclusion criteria for characteristics presentation. The RW analysis omitted 53 RCTs completed after June 2020, which remained unpublished. Of the 175 RCTs assessed, 98 were published, 71 demonstrated adequate reporting, and 25 had design limitations. Altogether, 118 RCTs (67.4%) exhibited at least 1 trait of RW. Multicenter designs and registrations post-2014 were independent protective factors against RW.Conclusion: Within the 175 RCTs included in RW analysis, 67.4% of the studies presented some form of RW. The varied characteristics of the identified RW indicators offer essential insights for more rational planning of future BoNT-A RCTs.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Novel Ablative Fractional 2,910-nm Erbium-Doped Fluoride Glass Fiber Laser for the Treatment of Photoaging in Fitzpatrick Skin Type IV. 新型烧蚀分数阶2910 nm掺铒氟化玻璃光纤激光器治疗Fitzpatrick皮肤IV型光老化。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-01-22 DOI: 10.1097/DSS.0000000000004546

Taryn N Murray, Mary Dick, Paul M Friedman

引用次数: 0

Reconstruction and Revision of a Large Multisubunit Defect of the Cheek, Nose, and Lip. 颊、鼻、唇大面积多亚基缺损的重建与修复。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-01-22 DOI: 10.1097/DSS.0000000000004550

Frank Z Jing, Addison M Demer, Nahid Y Vidal

引用次数: 0

Applying the Teach-Back Method to Wound Care Education After Mohs Micrographic Surgery: A Pilot Study. 应用背教法进行莫氏显微摄影术后创面护理教育的初步研究。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-01-21 DOI: 10.1097/DSS.0000000000004559

Neha Gupta, Sheena T Hill, Jeffrey F Scott, Christina Wong

引用次数: 0

Reconstructive Conundrum: Repair of a Large Upper Lip Defect. 重建难题：修复大面积上唇缺损。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-01-21 DOI: 10.1097/DSS.0000000000004551

Hannah J Porter, Michael Heath, Wesley Yu

引用次数: 0

Reconstruction of a Through-and-Through Auricular Defect With Full-Thickness Loss of the Postauricular Scalp. 完全性耳廓缺损伴耳后头皮全层缺损的重建。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-01-17 DOI: 10.1097/DSS.0000000000004549

Keegan O'Hern, Mary E Lohman, Addison M Demer

引用次数: 0

Factors Contributing to Poor Patient Reviews for Mohs Surgeons. 莫氏外科医生患者评价差的原因。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-01-16 DOI: 10.1097/DSS.0000000000004548

Natasha L Salmen, Deven P Curtis, Jacob W Fay, Jonathan T Chapple, Bharath Balu

引用次数: 0

Reconstruction of a Multisubunit Defect of the Nasal Ala and Medial Cheek. 鼻翼及内颊多亚单位缺损的重建。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-01-16 DOI: 10.1097/DSS.0000000000004547

Priscilla L Kojder, John A Carucci

引用次数: 0

Phenol Dilution With Saline Solution Versus Alcohol in Partial Matricectomy for Onychocryptosis. 苯酚稀释盐水溶液与酒精在部分基质切除术治疗足趾塌陷的比较。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-01-16 DOI: 10.1097/DSS.0000000000004541

Joaquín Espiñeira Sicre, Lucía García Sirvent, Juan Ruiz Sánchez, Pedro Álvarez Chinchilla, Laura García Fernández, Julia Miralles Botella

{"title":"Phenol Dilution With Saline Solution Versus Alcohol in Partial Matricectomy for Onychocryptosis.","authors":"Joaquín Espiñeira Sicre, Lucía García Sirvent, Juan Ruiz Sánchez, Pedro Álvarez Chinchilla, Laura García Fernández, Julia Miralles Botella","doi":"10.1097/DSS.0000000000004541","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004541","url":null,"abstract":"Background: Onychocryptosis significantly impacts quality of life. Chemical partial matricectomy with phenol is a common surgical treatment. The use of alcohol as a solvent during this procedure has been controversial. In vitro studies suggest that physiologic saline solution (PSS) may be a more effective solvent for phenol.Objective: To evaluate the in vivo efficacy of PSS as a phenol solvent, in terms of postoperative outcomes, compared to alcohol.Methods: A retrospective unicentric cohort study was conducted on patients who underwent partial chemical matricectomy with phenol for onychocryptosis. Sociodemographic and clinical variables were collected and compared between the alcohol and PSS groups. Clinical staging followed Martinez Nova and colleagues' classification. Patients were followed up over a 12-month period to assess postoperative complications.Results: The study population demonstrated typical characteristics of onychocryptosis, with a median age of 20 years. No statistically significant differences were found between the groups in terms of pain, infections, or bleeding postoperatively. There were also no differences in terms of recurrence, days of analgesic use, or need for antibiotic therapy (p > .05).Conclusion: The results suggest that PSS is as effective and safe as alcohol as a solvent for phenol in chemical partial matricectomy.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0