Dermatologic Surgery最新文献_第7页

Frozen Sections in Clinic as a Real-Time Diagnostic Adjunct for Urgent Dermatologic Cases. 临床冷冻切片作为紧急皮肤病病例的实时诊断辅助手段。

IF 2.2 3区医学

Dermatologic Surgery Pub Date : 2025-09-11 DOI: 10.1097/DSS.0000000000004854

Michael Kozlov, Leonard H Goldberg, Ziv Schwartz

引用次数: 0

Assessing the Risk: Infection After Mohs Surgery and Ear Wedge Excision Repair. 评估Mohs手术和耳楔切除修复后感染的风险。

IF 2.2 3区医学

Dermatologic Surgery Pub Date : 2025-09-11 DOI: 10.1097/DSS.0000000000004859

Jay R Patel, Norhan Shamloul, Mariana Chrispim Gimenez, Franki Lambert Smith, Marc D Brown

引用次数: 0

Participant Satisfaction, Effectiveness, and Safety With a Novel Dual-Applicator Cryolipolysis System: A Prospective, Multicountry Study. 参与者满意度，有效性和安全性与一种新的双涂抹器冷冻脂肪分解系统：一项前瞻性，多国研究。

IF 2.2 3区医学

Dermatologic Surgery Pub Date : 2025-09-10 DOI: 10.1097/DSS.0000000000004797

Roy G Geronemus, Jordan V Wang, Mitchel P Goldman, Sabrina Fabi, Suzanne Kilmer, Jens Altmann, Jean M Mazer, Ulf Samuelson, Terence Tan, Maria Ali, Meetu Bhogal, Vaishali Patel, Hongyan Qiao, Alda Karic

{"title":"Participant Satisfaction, Effectiveness, and Safety With a Novel Dual-Applicator Cryolipolysis System: A Prospective, Multicountry Study.","authors":"Roy G Geronemus, Jordan V Wang, Mitchel P Goldman, Sabrina Fabi, Suzanne Kilmer, Jens Altmann, Jean M Mazer, Ulf Samuelson, Terence Tan, Maria Ali, Meetu Bhogal, Vaishali Patel, Hongyan Qiao, Alda Karic","doi":"10.1097/DSS.0000000000004797","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004797","url":null,"abstract":"Background: Cryolipolysis is an effective, well-tolerated noninvasive subcutaneous fat reduction treatment.Objective: Assess participant satisfaction, effectiveness, and safety of a dual-applicator cryolipolysis system that can deliver simultaneous treatments.Materials and methods: Adult participants received treatment to the abdomen/flanks (midsection). Participants could also receive treatment to upper arms, thighs, and submental area. Primary end point was participant satisfaction with midsection results at 12 weeks after final treatment. Secondary end points included independent photography review, participant satisfaction with additional body areas, and overall satisfaction. Exploratory end points included 3D imaging of midsection volumetric changes and assessments at 4 weeks after initial treatment. Safety was monitored throughout.Results: Of 110 treated participants, 75% were female. Mean age and body mass index were 43 years and 25.1 kg/m2, respectively. Of 96 evaluable participants, 83.3% (80/96) were \"satisfied/very satisfied\" with midsection results. Reviewers correctly identified 88.0% (81/92) of baseline versus 12 weeks after final treatment midsection images. Mean (SD) subcutaneous fat volume loss was 194.8 (492.3) mL at 12 weeks after final treatment (p < .001). Visible improvements were noted at 4 weeks after initial treatment by a majority of physician reviewers and participants. Five (4.5%, 5/110) participants reported 7 treatment-emergent adverse device effects.Conclusion: The dual-applicator cryolipolysis system demonstrated high participant satisfaction, effectiveness, and safety.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NivobotulinumtoxinA in the Treatment of Lateral Canthal Lines Alone and With Concurrent Treatment of Glabellar Lines. 牛肉毒杆菌毒素单独治疗外侧眦线和同时治疗眉间线。

IF 2.2 3区医学

Dermatologic Surgery Pub Date : 2025-09-09 DOI: 10.1097/DSS.0000000000004829

Jean Carruthers, Janet C DuBois, Daniel P Friedmann, Brenda LaTowsky, Melanie D Palm, Jason K Rivers, Susan H Weinkle, Sara Duggan, Kim Enfield, Lisa M Donofrio

{"title":"NivobotulinumtoxinA in the Treatment of Lateral Canthal Lines Alone and With Concurrent Treatment of Glabellar Lines.","authors":"Jean Carruthers, Janet C DuBois, Daniel P Friedmann, Brenda LaTowsky, Melanie D Palm, Jason K Rivers, Susan H Weinkle, Sara Duggan, Kim Enfield, Lisa M Donofrio","doi":"10.1097/DSS.0000000000004829","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004829","url":null,"abstract":"Background: Botulinum neurotoxins in aesthetic medicine require reconstitution, which may cause administration errors.Objective: To evaluate liquid nivobotulinumtoxinA treatment of lateral canthal lines (LCL) and glabellar lines (GL).Materials and methods: Participants with moderate-to-severe LCL with/without moderate-to-severe GL were enrolled in 2 double-blind randomized clinical trials. Study 002 participants received nivobotulinumtoxinA 24 U or placebo for LCL treatment. Study 006 participants received nivobotulinumtoxinA 24 U (LCL), nivobotulinumtoxinA 44 U (LCL+GL), or placebo. Each study allowed up to 2 additional doses. The composite primary end point was the proportion of participants achieving ≥2-grade improvement on the Facial Wrinkle Scale (FWS) by investigator and participant assessment at maximum smile; the coprimary end point was investigator- and participant-assessed FWS \"none or mild\" rating.Results: At Day 30, significant responder rates versus placebo were observed for LCL in Study 002 (30.3% vs 2.6%, p < .001) and for LCL and LCL+GL in Study 006 (20.6% and 22.8% vs 0%, p < .001) for the composite end point. \"None or mild\" investigator/participant assessment of LCL (Study 002: 62.7%/56.5%; Study 006: 56.4%/43.6%) and LCL+GL (60.8%/47.3%) were significantly higher versus placebo (p < .001). Headache was the most common adverse event.Conclusion: Liquid nivobotulinumtoxinA was effective and well-tolerated for treating moderate-to-severe LCL with/without GL.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidental Histologic Findings During Mohs Micrographic Surgery: A Systematic Review. 莫氏显微摄影手术中偶然的组织学发现：系统回顾。

IF 2.2 3区医学

Dermatologic Surgery Pub Date : 2025-09-08 DOI: 10.1097/DSS.0000000000004856

Benjamin R Cooper, Taha Rasul, Anthony Concilla, Travis Wayne Blalock, Arianne E Chavez

{"title":"Incidental Histologic Findings During Mohs Micrographic Surgery: A Systematic Review.","authors":"Benjamin R Cooper, Taha Rasul, Anthony Concilla, Travis Wayne Blalock, Arianne E Chavez","doi":"10.1097/DSS.0000000000004856","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004856","url":null,"abstract":"Background: Mohs micrographic surgery (MMS) allows for precise excision of skin cancers with intraoperative histologic margin assessment. Incidental findings-unexpected histopathologic features unrelated to the primary lesion-are occasionally discovered but scantily characterized in the literature.Objective: To systematically review published cases of incidental histologic findings identified during MMS, with attention to their frequency, clinical implications, and management.Methods: A systematic review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines utilizing PubMed, Wiley Online Library, Google Scholar, and Cochrane Library. Data were extracted regarding patient demographics, tumor type and location, incidental findings, associated implications, treatment, and follow-up.Results: Twenty-nine studies were selected for inclusion, describing 680 patients (aged 36-90 years) with incidental findings, of which 26 were findings distinct from the original tumor. One study reported 610 patients with incidental basal and squamous cell carcinoma. Among the remaining 28 studies, the most frequent incidental findings included benign syringomatous hyperplasia, syringomas, Merkel cell carcinoma, and melanoma, with further treatment required for 15.7% of these incidental findings (11/70). In aggregate, 91.3% of reported incidental findings required further treatment (621/680).Conclusion: Incidental findings during MMS can be clinically important. Although many are benign, others may alter prognosis and management. Awareness of these findings and standardized reporting may enhance patient outcomes.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Analysis of UV Lamps for Identifying Biopsy Sites in Dermatologic Surgery. 紫外线灯在皮肤外科活检部位识别中的比较分析。

IF 2.2 3区医学

Dermatologic Surgery Pub Date : 2025-09-08 DOI: 10.1097/DSS.0000000000004855

Bharath Balu, Andrea J Borba, Michael L Ramsey

引用次数: 0

Fractional CO2 Versus Radiofrequency as Hair Regrowth Enhancers for Female Androgenic Alopecia: A Randomized Controlled Trial. 少量二氧化碳与射频作为女性雄激素性脱发的头发再生促进剂：一项随机对照试验。

IF 2.2 3区医学

Dermatologic Surgery Pub Date : 2025-09-08 DOI: 10.1097/DSS.0000000000004839

Rana F Hilal, Eman Shaarawy, Nehal Ahmed, Solwan I El-Samanoudy

{"title":"Fractional CO2 Versus Radiofrequency as Hair Regrowth Enhancers for Female Androgenic Alopecia: A Randomized Controlled Trial.","authors":"Rana F Hilal, Eman Shaarawy, Nehal Ahmed, Solwan I El-Samanoudy","doi":"10.1097/DSS.0000000000004839","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004839","url":null,"abstract":"Background: Androgenic alopecia (AGA) is a cosmetically disfiguring condition, which accounts for most cases of diffuse hair loss among females, negatively impacting their quality of life. Combining Fractional CO2 (FCO2) or Fractional Microneedling Radiofrequency (FMRF) with topical minoxidil 5% could achieve a better clinical outcome.Objective: To compare efficacy and safety of FCO2 and FMRF, combined with minoxidil, for the treatment of female AGA.Methods: Thirty patients with female AGA were randomly assigned to 2 groups (simple computerized randomization). Group A patients received FCO2 to 1 randomly selected side of the scalp, and Group B patients received FMRF to 1 randomly selected side of the scalp (picking masked labeled cards). Patients received minoxidil 5%.Results: Significant increase in trichoscopic hair counts and density was found after treatment with each modality whether minoxidil 5% alone, minoxidil combined with FCO2, or minoxidil combined with FMRF. A significantly greater increase in trichoscopic hair counts and density followed the treatment with minoxidil + FMRF, compared to either minoxidil + FCO2 or minoxidil alone.Conclusion: It can be proposed that combining FMRF with minoxidil for the treatment of female AGA could be associated with higher efficacy and tolerability, compared to the other treatment modalities.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Avoiding Electrocautery: Hemostatic Agents for Perioperative Bleeding in Mohs Micrographic Surgery. 避免触电：莫氏显微摄影术围手术期出血的止血剂。

IF 2.2 3区医学

Dermatologic Surgery Pub Date : 2025-09-05 DOI: 10.1097/DSS.0000000000004819

George M Jeha, Hannah R Malinosky, Jacob Beer, Keyvan Nouri, Sino Mehrmal, Stanislav N Tolkachjov

{"title":"Avoiding Electrocautery: Hemostatic Agents for Perioperative Bleeding in Mohs Micrographic Surgery.","authors":"George M Jeha, Hannah R Malinosky, Jacob Beer, Keyvan Nouri, Sino Mehrmal, Stanislav N Tolkachjov","doi":"10.1097/DSS.0000000000004819","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004819","url":null,"abstract":"Background: Bleeding remains a frequent complication during Mohs micrographic surgery, particularly among patients receiving anticoagulant or antiplatelet therapy. The growing use of these medications has prompted increased exploration of adjunctive methods to improve perioperative hemostasis.Objective: To systematically review the literature on topically and locally administered hemostatic agents used to reduce bleeding in Mohs micrographic surgery.Methods: A systematic search of PubMed, Scopus, Cochrane, and EMBASE was conducted through March 2024. Original studies evaluating hemostatic agents applied topically or by local injection during Mohs micrographic surgery were included.Results: Seven studies met inclusion criteria, encompassing 458 patients. Agents evaluated included tranexamic acid, brimonidine gel, hemostatic powders, and microporous polysaccharide materials. These agents were generally well tolerated and associated with reductions in intraoperative and postoperative bleeding.Conclusion: Locally administered hemostatic agents offer a promising adjunct to improve bleeding control in Mohs micrographic surgery. Their use may be particularly beneficial in patients at elevated bleeding risk and warrants further investigation in larger, controlled studies.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early Takedown of Postauricular, Melolabial, and Paramedian Forehead Interpolation Flaps: A Retrospective Cohort Study. 耳后、唇边和旁位前额插补皮瓣的早期取下：一项回顾性队列研究。

IF 2.2 3区医学

Dermatologic Surgery Pub Date : 2025-09-05 DOI: 10.1097/DSS.0000000000004852

Luke A Scherz, Michael Renzi, Tara Jennings, Naomi Lawrence

{"title":"Early Takedown of Postauricular, Melolabial, and Paramedian Forehead Interpolation Flaps: A Retrospective Cohort Study.","authors":"Luke A Scherz, Michael Renzi, Tara Jennings, Naomi Lawrence","doi":"10.1097/DSS.0000000000004852","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004852","url":null,"abstract":"Background: Staged interpolation flaps remain central to reconstructing complex facial defects, with traditional pedicle takedown occurring approximately 3 weeks postoperatively. However, prolonged pedicle duration may cause patient discomfort and impair quality of life.Objective: To evaluate the safety and outcomes of early takedown (<21 days) versus conventional takedown (≥21 days) across 3 commonly used interpolation flaps: postauricular, melolabial, and paramedian forehead.Methods/materials: Retrospective cohort study including patients who underwent one of the 3 interpolation flaps. Patients were stratified by takedown timing. Complication rates and flap characteristics were compared between early and conventional takedown groups.Results: A total of 141 patients were included: 75 postauricular (52 early), 38 melolabial (23 early), and 28 paramedian forehead flaps (14 early). Across all flap types, complication rates (infection, dehiscence, necrosis) were low and did not differ significantly between early and conventional takedown groups. Flap and defect sizes were comparable.Conclusion: Early takedown of postauricular, melolabial, and paramedian forehead interpolation flaps at 2 weeks is safe and not associated with increased complications or poor surgical outcome.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Modified Scalpel Handle Technique. 改良手术刀柄技术。

IF 2.2 3区医学

Dermatologic Surgery Pub Date : 2025-09-04 DOI: 10.1097/DSS.0000000000004726

Michael Goldenberg, Michael Anderson, Conway Huang, Daniel Bergman

引用次数: 0