Dentistry Journal最新文献

{"title":"A Survey of Oral Health-Related Quality of Life for Adults with Cerebral Palsy in Australia.","authors":"Karen Lansdown, Kim Bulkeley, Margaret McGrath, Michelle Irving, Claudia Zagreanu, Hayley Smithers-Sheedy","doi":"10.3390/dj13090407","DOIUrl":"10.3390/dj13090407","url":null,"abstract":"<p><p><b>Objective:</b> Our aim was to investigate the oral health-related quality of life (OHRQoL) and dental care experiences of adults with Cerebral Palsy (CP). <b>Methods:</b> In 2023, adults with CP and their caregivers from four Australian states completed questionnaires, including the Oral Health Impact Profile-14 (OHIP-14). Non-parametric tests were conducted to analyze associations between demographic and CP-related variables and OHRQoL. <b>Results:</b> A total of 69 respondents participated, including <i>n</i> = 22 adults with CP and <i>n</i> = 47 caregivers of adults with CP. Most adults with CP were diagnosed with a spastic motor type (46/69, 66%), with bilateral spasticity being the most common (30/46, 65%). The mean OHIP-14 score was 10.3 ± 9.3 (mean ± SD). Nearly 70% reported challenges cleaning their teeth, over 25% lacked a dentist, more than 60% found dental exams challenging, and nearly 50% required specialized dental care. In bivariate analysis, OHIP-14 was associated with daily oral care routines (<i>p</i> = 0.012) and \"simple dental check-up\" (<i>p</i> = 0.017). There was a statistically significant relationship between socio-economic status and scores for the handicap dimension (<i>p</i> = 0.040). Higher OHIP-14 scores were associated with greater levels of impairment regarding gross motor (<i>p</i> = 0.199), manual functioning limitations (<i>p</i> = 0.001), speech (<i>p</i> = 0.123), and communication function scales (<i>p</i> = 0.319). <b>Conclusion:</b> Adults with CP reported challenges participating in and maintaining oral health and accessing dental care, influenced by physical, functional, and socio-economic factors. These findings indicate the need for inclusive care and strategies to support access to services.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12468944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Four-Week Evaluation of the Interaction Pattern Among Saccharibacteria, Nitrate-Reducing Bacteria, and Periodontopathogens in Orthodontic Miniscrew Implants.","authors":"Boy M Bachtiar, Endang W Bachtiar, Nicholas S Jakubovics, Turmidzi Fath, Sariesendy Sumardi, Nada Ismah, Natalina Haerani, Fatimah Maria Tadjoedin, Zamri Radzi","doi":"10.3390/dj13090405","DOIUrl":"10.3390/dj13090405","url":null,"abstract":"<p><p><b>Background/Objective</b>: Orthodontic mini-implants (MI) create new niches that may alter the oral microbiota and modulate host immune responses. While clinical inflammation is not always evident, microbial and molecular changes may precede visible signs of peri-implant infection. This study investigated microbial shifts and inflammatory responses following MI placement, with a focus on Saccharibacteria, nitrate-reducing bacteria (NRB), and periodontopathogens. <b>Methods</b>: Saliva and peri mini-implant crevicular fluid (PMICF) samples were collected from eight orthodontic patients at baseline (T0), one week (T1), and one month (T2) after mini-implant placement. DNA was extracted from each saliva and PMICF sample and pooled across the eight patients for each time point. The pooled DNA were then subjected to 16S rRNA gene sequencing using the Oxford Nanopore MinION platform. Statistical analysis was performed to determine shifts in bacterial abundance, diversity, and co-occurrence patterns across the different sample types (saliva vs. PMICF) and time points. <b>Results</b>: Alpha diversity decreased in PMICF at T2, while it remained stable in saliva samples. Periodontopathogens (<i>Porphyromonas gingivalis</i>, <i>Treponema denticola</i>, <i>Fusobacterium nucleatum</i>) increased in PMICF at T2, while NRB and Saccharibacteria, along with a representative host bacterium (<i>Schaalia odontolytica</i>), remained relatively stable. Co-occurrence analysis showed antagonistic relationships between Saccahribacteria/NRB and periodontopathogens. IL-6 significantly decreased from T1 to T2, while CRP showed a non-significant downward trend. The expression of nitrate reductase genes <i>narG</i> and <i>napA</i> remained stable across time intervals. <b>Conclusions</b>: Despite no clinical inflammation, MI placement led to localized microbial shift and mild inflammatory responses. NRB and Saccharibacteria's stability and antagonistic relationship to periodontopathogens may indicate that they could be involved in maintaining microbial homeostasis. These findings highlight possible early biomarkers and ecological strategies to support oral health in MI patients.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12469005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Qualitative Enhancement of the Tooth-Filling Interface Using Cold Atmospheric Plasma.","authors":"Madline Priska Gund, Jusef Naim, Muhammad Al Muhammad, Antje Lehmann, Axel Schindler, Matthias Hannig, Stefan Rupf","doi":"10.3390/dj13090406","DOIUrl":"10.3390/dj13090406","url":null,"abstract":"<p><p><b>Objective</b>: To evaluate the effects of cold atmospheric plasma (CAP) on adhesive bonding in Class II composite restorations in vitro. <b>Methods</b>: Forty-eight standardized Class II cavities were assigned to six groups (<i>n</i> = 8), varying in phosphoric acid conditioning, CAP treatment (1.5 W or 3 W), composite filling, and thermo-mechanical loading (TML). Evaluations included dye penetration, adhesive layer morphology, resin tag length, and hybrid layer thickness. <b>Results</b>: CAP combined with phosphoric acid (H₃PO₄) significantly increased hybrid layer thickness and resin tag length (<i>p</i> < 0.006). The lowest dye penetration was observed in Groups 1 and 4. <b>Conclusions</b>: CAP in combination with phosphoric acid improved the adhesive interface in Class II cavities. CAP alone showed limited benefits, and higher power levels may negatively affect bonding.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12468222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Individually Trained Oral Prophylaxis (iTOP) Education on Long-Term Oral Health in Medical and Dental Students: A Two-Year Prospective Cohort Study.","authors":"Zvonimir Lukac, Brigita Maric, Josip Kapetanovic, Mislav Mandic, Ivona Musa Leko, Andrija Petar Bosnjak","doi":"10.3390/dj13090404","DOIUrl":"10.3390/dj13090404","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Preventive oral health education plays a key role in preparing future healthcare professionals to promote and maintain good oral hygiene. Individually Trained Oral Prophylaxis (iTOP) is a structured, personalized educational program that emphasizes correct brushing techniques and interdental cleaning. This study aimed to evaluate the long-term effectiveness of a single-session iTOP intervention on clinical oral health outcomes among medical and dental students. <b>Methods</b>: A 2-year prospective cohort study included 82 first- and fourth-year medical and dental students at the University of Mostar, Bosnia and Herzegovina. The researchers randomly assigned participants to an iTOP intervention group or a control group. The primary analysis used multivariable linear mixed-effects models for repeated measures, adjusted for study program, academic year, smoking status, and baseline oral-hygiene habits, with effect sizes reported alongside 95% confidence intervals. Clinical periodontal parameters-plaque index, bleeding on probing, and probing depth-were assessed at baseline, three months, and two years. All participants received professional cleaning and oral hygiene kits. Only the intervention group received personalized iTOP training, consisting of a single session with brief reinforcement at the 3-month follow-up. This study was registered at ClinicalTrials.gov (NCT07085013). <b>Results</b>: Seventy-six students completed the follow-up. The iTOP group had significantly lower plaque index and bleeding scores at both follow-up points (<i>p</i> < 0.001) compared to the control group. Baseline differences were observed between subgroups (medical vs. dental; younger vs. older students), but these diminished over time. At the 2-year follow-up, only the plaque index remained significantly improved, while other clinical parameters returned to values comparable to baseline. <b>Conclusions</b>: The iTOP program resulted in significant short-term improvements in oral health among medical and dental students. For sustained long-term outcomes, iTOP or similar structured oral health education programs should be integrated into medical and dental curricula. Enhancing oral health awareness among healthcare providers may ultimately contribute to improved public oral health outcomes. Given the single-center design and the single-session nature of the intervention, the results should be interpreted with caution.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12469037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modular Deep-Learning Pipelines for Dental Caries Data Streams: A Twin-Cohort Proof-of-Concept.","authors":"Ștefan Lucian Burlea, Călin Gheorghe Buzea, Florin Nedeff, Diana Mirilă, Valentin Nedeff, Maricel Agop, Dragoș Ioan Rusu, Laura Elisabeta Checheriță","doi":"10.3390/dj13090402","DOIUrl":"10.3390/dj13090402","url":null,"abstract":"<p><p><b>Background:</b> Dental caries arise from a multifactorial interplay between microbial dysbiosis, host immune responses, and enamel degradation visible on radiographs. Deep learning excels in image-based caries detection; however, integrative analyses that combine radiographic, microbiome, and transcriptomic data remain rare because public cohorts are seldom aligned. <b>Objective:</b> To determine whether three independent deep-learning pipelines-radiographic segmentation, microbiome regression, and transcriptome regression-can be reproducible implemented on non-aligned datasets, and to demonstrate the feasibility of estimating microbiome heritability in a matched twin cohort. <b>Methods:</b> (i) A U-Net with ResNet-18 encoder was trained on 100 annotated panoramic radiographs to generate a continuous caries-severity score from a predicted lesion area. (ii) Feed-forward neural networks (FNNs) were trained on supragingival 16S rRNA profiles (81 samples, 750 taxa) and gingival transcriptomes (247 samples, 54,675 probes) using randomly permuted severity scores as synthetic targets to stress-test preprocessing, training, and SHAP-based interpretability. (iii) In 49 monozygotic and 50 dizygotic twin pairs (<i>n</i> = 198), Bray-Curtis dissimilarity quantified microbial heritability, and an FNN was trained to predict recorded TotalCaries counts. <b>Results:</b> The U-Net achieved IoU = 0.564 (95% CI 0.535-0.594), precision = 0.624 (95% CI 0.583-0.667), recall = 0.877 (95% CI 0.827-0.918), and correlated with manual severity scores (r = 0.62, <i>p</i> < 0.01). The synthetic-target FNNs converged consistently but-as intended-showed no predictive power (R² ≈ -0.15 microbiome; -0.18 transcriptome). Twin analysis revealed greater microbiome similarity in monozygotic versus dizygotic pairs (0.475 ± 0.107 vs. 0.557 ± 0.117; <i>p</i> = 0.0005) and a modest correlation between salivary features and caries burden (r = 0.25). <b>Conclusions:</b> Modular deep-learning pipelines remain computationally robust and interpretable on non-aligned datasets; radiographic severity provides a transferable quantitative anchor. Twin-cohort findings confirm heritable patterns in the oral microbiome and outline a pathway toward future clinical translation once patient-matched multi-omics are available. This framework establishes a scalable, reproducible foundation for integrative caries research.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12468722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Material-Dependent Microhardness Response to Preheating in Nanoparticulate Composite Resins Cured with High-Intensity Light.","authors":"Jorge I Fajardo, César A Paltán, Ana Armas-Vega, Camila Campanella-Maldonado, Silvio Requena-Cisneros","doi":"10.3390/dj13090403","DOIUrl":"10.3390/dj13090403","url":null,"abstract":"<p><strong>Background/objectives: </strong>Composite resins are widely used in restorative dentistry due to their aesthetic properties and ease of handling. Preheating prior to light polymerization has been proposed to improve flowability, degree of conversion, and mechanical properties. This in vitro study aimed to evaluate the effect of preheating on the microhardness of three nanoparticulate composite resins-IPS Empress Direct (Ivoclar), Filtek Z350 XT (3M-ESPE), and Forma (Ultradent)-when cured with a high-power LED light.</p><p><strong>Methods: </strong>Sixty disc-shaped samples (<i>n</i> = 20 per material) were fabricated and divided into preheated and non-preheated groups. After polishing and 24 h storage in distilled water at 37 °C, samples were subjected to Knoop microhardness testing under a 300 g load for 15 s. Statistical analysis was conducted using R software.</p><p><strong>Results: </strong>Preheating produced a significant increase in surface microhardness for IPS Empress Direct (32.8%) and Filtek Z350 XT (5.8%) (<i>p</i> < 0.05 for both), whereas Forma showed no significant change.</p><p><strong>Conclusions: </strong>Under the conditions of this in vitro study, preheating can enhance the mechanical performance of specific composite resins by increasing microhardness; however, the effect is material-dependent.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12468774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Health Status, Behavior, and Knowledge of Patients with Cardiovascular Disease and Associated Risk Factors in Odisha: A Cross-Sectional Survey.","authors":"Lora Mishra, Muskan Sharma, Naomi Ranjan Singh, Gathani Dash, Satya Ranjan Misra, Krzysztof Sokolowski, Manoj Kumar, Rupsa Das, Suresh Kumar Behera, Barbara Lapinska","doi":"10.3390/dj13090401","DOIUrl":"10.3390/dj13090401","url":null,"abstract":"<p><p><b>Background:</b> Cardiovascular diseases (CVDs) are linked with poor oral health outcomes, yet data on oral health status, behaviors, and awareness among CVD patients in Odisha remain scarce. This study aimed to assess the self-reported oral health status, behaviors, and knowledge among patients with CVD and associated risk factors. <b>Methods:</b> A cross-sectional survey was conducted among 391 patients aged 40-80 years attending dental and cardiology OPDs at a tertiary care center in Bhubaneswar. Participants were grouped into control, at-risk, and established CVD categories. A 24-item questionnaire and panoramic radiographic examination were used to assess oral health. Data were analyzed using the chi-squared test and Kappa statistics. <b>Results:</b> Patients with established CVD reported significantly higher prevalence of oral health problems, poor oral hygiene behaviors, and lower awareness compared to controls. Clinical findings revealed higher rates of periodontal bone loss, caries, and periapical radiolucency in the CVD group. Agreement between radiographic examiners was high. <b>Conclusions:</b> There is a substantial burden of oral disease and poor oral health awareness among patients with CVD in Odisha. These findings emphasize the need for integrated oral health education and care protocols in cardiovascular patient management.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12468224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Five Prognostic Factors in the Eruption of Palatally Impacted Canines Following Diode Laser Disinclusion: A Case Series Study.","authors":"Martina Horodynski, Francesca Crocamo, Adriana Assunta De Stefano, Gerardo La Monaca, Nicola Pranno, Gaspare Palaia, Umberto Romeo, Gabriella Galluccio","doi":"10.3390/dj13090399","DOIUrl":"10.3390/dj13090399","url":null,"abstract":"<p><p><b>Background:</b> This case series study aims to evaluate the spontaneous eruption of impacted canines following diode laser disinclusion surgery without orthodontic traction, and to analyze the correlation with five prognostic factors: age, sex of the patient, angle α, sector, and height of inclusion of the canine. <b>Methods:</b> The sample included 15 patients aged 13-30 years and 20 palatally impacted canines. The patients' records were collected, and prognostic factors were assessed. All patients underwent disinclusion surgery using a diode laser (K-Laser, Eltech, Blue Derma) and post-surgery, canines were monitored with intraoral scans and photos at 1 week, 8 weeks (T1), and 16 weeks (T2). The STL files were superimposed with the open-source software MeshLab (MeshLab 2023.12, Visual Computing Lab, Pisa, Italy), and the eruption values were measured. Through multiple linear regression analysis, the relationships between the five prognostic factors and the total spontaneous eruption value were analyzed. <b>Results:</b> The canines treated in this study responded with an average eruption of 4.70 mm. For the prognostic factors sex (<i>p</i> = 0.94) and angle α (<i>p</i> = 0.12), no statistically significant relationship with eruption was found. The variables age (<i>p</i> < 0.001), sector II (<i>p</i> = 0.02), sector III (<i>p</i> = 0.03), sector IV (<i>p</i> = 0.06), and inclusion height (<i>p</i> < 0.001) had negative linear coefficients. Consequently, as the values of these three prognostic factors increased, a lower eruption of the included element measured in millimeters was obtained. <b>Conclusions:</b> All canines successfully erupted following the disinclusion procedure, avoiding the use of orthodontic traction. Patient sex and the α angle of impaction were not reliable predictors of eruption outcomes. In contrast, age, sector, and inclusion height measured via CBCT showed high statistical significance and could be used as prognostic factors to predict the eruptive response following disinclusion surgery.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12468732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Myokines on the Bone Metabolism of Craniofacial Region: A Scoping Review.","authors":"Ahana S Rajan, Eiji Tanaka","doi":"10.3390/dj13090400","DOIUrl":"10.3390/dj13090400","url":null,"abstract":"<p><p><b>Background:</b> The craniofacial region is functionally unique, with close interaction between muscles and bones during mastication, speech, and facial expression. Although myokines, muscle-derived signaling molecules, are increasingly being studied in relation to bone metabolism, most studies have focused on limb muscles and long bones. Given the developmental and functional specificity of craniofacial structures, this article aims to map the current evidence on myokines involved in craniofacial bone metabolism and to identify gaps in order to guide future research. <b>Methods</b>: We conducted a literature search in PubMed and Scopus (January 2000-July 2025), combining both free-text keywords and MeSH terms to ensure comprehensive retrieval of relevant articles. <b>Results:</b> Nine articles from the extensive search were included in this review that adhered to the eligibility criteria. The myokines that were reported include interleukin-6, insulin like growth factor-1, and myostatin and irisin. <b>Conclusions:</b> Further research is required into the mechanism by which craniofacial muscle-derived myokines regulate local bone metabolism, as this knowledge could pave the way for novel therapeutic strategies that leverage myokine signaling, which could be applied in the context of orthodontic and orthognathic treatments, maxillofacial reconstruction, or age-related bone loss.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12469128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An International Online Survey on Oral Hygiene Issues in Patients with Epidermolysis Bullosa.","authors":"Giovanna Garuti, Giacomo Setti, Chiara Lucia Guidetti, Gaela Barbieri, Ugo Consolo, Pierantonio Bellini","doi":"10.3390/dj13090398","DOIUrl":"10.3390/dj13090398","url":null,"abstract":"<p><p><b>Background</b>: Inherited epidermolysis bullosa (EB) includes a group of rare genetic disorders affecting the skin and mucous membranes. These disorders are characterized by extreme fragility and blister formation after minimal or no trauma. Oral and systemic manifestations vary by subtype; the more severe forms often present with extensive intra-oral blistering, scarring, microstomia, vestibular obliteration, ankyloglossia, and-in some cases-oral cancer. This study aims to collect data on oral-health practices and challenges in people with EB to inform preventive strategies and dental care. <b>Methods</b>: An international, structured online questionnaire with 31 items was distributed to individuals with a confirmed diagnosis of EB. The survey explored clinical and oral manifestations, home-care routines (oral hygiene and diet), experiences with dental professionals, and the impact of oral health on quality of life. <b>Results</b>: Eighty-two questionnaires were completed. Dystrophic EB was the most often reported subtype (69.5%). Most respondents (67.1%) experienced recurrent oral blisters and/or erosions. Many reported relying exclusively on soft foods and struggling with mechanical plaque removal because of microstomia and pseudo-syndactyly. Severe oral pain hindered effective brushing in 17% of participants. Hand contractures and microstomia interfered with oral hygiene in 74% and 31% of participants, respectively. Nearly 30% sought dental care only when in pain. Among those who did not attend regular check-ups or hygiene sessions (44.6%), the most cited reason was that dental clinics were inadequately equipped or trained to manage EB. <b>Conclusions</b>: Because dental procedures carry significant risks for patients with EB, preventive care should begin in early childhood. Yet many patients are still insufficiently informed about essential preventive measures and lack access to dental professionals trained in EB management.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 9","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12468093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}