Forum Dermatologicum最新文献_第2页

Lichen planus pigmentosus inversus limited to the umbilicus — a case report with dermoscopic findings 局限于脐部的扁平色素苔藓- 1例皮肤镜检查结果

Forum Dermatologicum Pub Date : 2023-09-29 DOI: 10.5603/fd.a2023.0014

Kinga Kołcz, Elżbieta Ostańska, Katarzyna Kosior, Adam Reich, Magdalena Żychowska

引用次数: 0

The diagnosis and treatment of androgenetic alopecia: a review of the most current management 雄激素源性脱发的诊断和治疗:最新的管理回顾

Forum Dermatologicum Pub Date : 2023-09-29 DOI: 10.5603/fd.95391

Karol Śliwa, Daria Synia, Waldemar Placek, Agnieszka Owczarczyk-Saczonek

{"title":"The diagnosis and treatment of androgenetic alopecia: a review of the most current management","authors":"Karol Śliwa, Daria Synia, Waldemar Placek, Agnieszka Owczarczyk-Saczonek","doi":"10.5603/fd.95391","DOIUrl":"https://doi.org/10.5603/fd.95391","url":null,"abstract":"Androgenetic alopecia is a widespread problem in contemporary dermatology, as it may also affect many young patients, in particular males, making them more prone to anxiety and depression which may be caused by a distorted body image. These behavioural problems may occur in older individuals as well. That is why, there is an obvious need for further development in that area of dermatology, which should also include discovering new therapies. In men, the diagnosis of androgenetic alopecia is quite simple, and the treatment usually involves incorporating minoxidil and/or finasteride. Switching from topical minoxidil to its systemic form as well as from finasteride to dutasteride may give better results in some patients. In general, male pattern hair loss (MPHL) is a chronic disease that may demand pharmacological treatment in the long term, which is often unlimited. Therefore, and also considering the patients’ concerns involving the systemic usage of 5α-reductase inhibitors as well as the limitations of current therapies, some specialists use topical finasteride, dutasteride in mesotherapy and many other additional modalities. When it comes to female pattern hair loss (FPHL), in most cases it is also a chronic entity, which especially in younger women demands performing extended lab testing in the search for potential hyperandrogenism. It is necessary to remember that especially in women the condition may be triggered by many environmental and other additional factors, so taking that into consideration may be helpful in some patients.","PeriodicalId":112619,"journal":{"name":"Forum Dermatologicum","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135249119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of EFFACLAR H ISO-BIOME preparations as an adjunct to conventional treatment of acne vulgaris — results of an observational study EFFACLAR H ISO-BIOME制剂作为寻常性痤疮常规治疗的辅助治疗的有效性-一项观察性研究的结果

Forum Dermatologicum Pub Date : 2023-09-29 DOI: 10.5603/fd.97344

Dominika Kwiatkowska, Diana Wolańska-Buzalska, Mikołaj Łanocha, Barbara Zegarska, Beata Bergler-Czop, Adam Reich

{"title":"Effectiveness of EFFACLAR H ISO-BIOME preparations as an adjunct to conventional treatment of acne vulgaris — results of an observational study","authors":"Dominika Kwiatkowska, Diana Wolańska-Buzalska, Mikołaj Łanocha, Barbara Zegarska, Beata Bergler-Czop, Adam Reich","doi":"10.5603/fd.97344","DOIUrl":"https://doi.org/10.5603/fd.97344","url":null,"abstract":"Background: Although topical dermocosmetics are widely used care products, only a few studies investigated their effectiveness in enhancing the tolerance and efficacy of medical anti-acne therapies. The primary objective of this study was to assess the safety and efficacy of EFFACLAR H ISO-BIOME cream and washing cream as an adjunct to pharmacological treatment (local and/or systemic) administered for at least 12 weeks in patients with mild to very severe acne vulgaris. Material and methods: This observational study was conducted in patients (n = 306) aged 14 years and over with mild to very severe [Global Acne Severity Scale (GEA) 1–5] acne vulgaris. Participants were instructed to apply the EFFACLAR H ISO-BIOME cream and washing cream twice daily for at least 12 weeks along with prescribed anti-acne therapy (topical agents, oral isotretinoin, or systemic antibiotics/ /spironolactone combined with topical agents). Results: The treatment regimen led to an improvement in GEA scores in 88.9% of all patients (p < 0.05). Statistically significant changes were observed in the reduction of sebum secretion, number of papules and pustules, postinflammatory hyperpigmentation, and erythema (p < 0.05). The vast majority of dermatologists and patients rated the tolerance of the products as very good (97% and 94%, respectively). The quality of life of most patients improved by the end of the study. Conclusions: EFFACLAR H ISO-BIOME cream and washing cream are safe and effective products used as adjunctive treatment to topical or systemic therapy of mild to very severe acne vulgaris.","PeriodicalId":112619,"journal":{"name":"Forum Dermatologicum","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135248132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dutasteride mesotherapy in the treatment of androgenetic alopecia 杜他雄胺美施疗法治疗雄激素性脱发

Forum Dermatologicum Pub Date : 2023-09-29 DOI: 10.5603/fd.96555

Jakub Kobiałka, Ugo Giordano

引用次数: 0

Infantile seborrheic dermatitis differential diagnosis based on case report 基于病例报告的婴儿脂溢性皮炎鉴别诊断

Forum Dermatologicum Pub Date : 2023-09-29 DOI: 10.5603/fd.a2023.0010

Natalia Bień, Maria Rajczak, Klaudia Lipińska, Joanna Narbutt, Małgorzata Skibińska, Aleksandra Lesiak

{"title":"Infantile seborrheic dermatitis differential diagnosis based on case report","authors":"Natalia Bień, Maria Rajczak, Klaudia Lipińska, Joanna Narbutt, Małgorzata Skibińska, Aleksandra Lesiak","doi":"10.5603/fd.a2023.0010","DOIUrl":"https://doi.org/10.5603/fd.a2023.0010","url":null,"abstract":"Infantile seborrheic dermatitis often occurs during the first three months of life and most frequently presents as erythema and greasy scales located especially on the scalp (commonly called “cradle cap”). Usually, it is a mild, self-limiting condition. The severe, erythrodermic clinical appearance is rare and often demands differential diagnosis with other more serious skin conditions. We report a case of severe seborrheic dermatitis in an infant. A 5-weeks male infant presented with erythrodermic scaling lesions and exfoliation of the outermost layer of the epidermis, which had appeared after birth. Greasy scales were observed on the scalp, eyelids, and face accompanied by inflammation of the eyelids. Moreover, erythematous, well-demarcated lesions were noticed in the neck folds, behind the ears, in the axillary region, and diaper area. Considering the severe clinical appearance, additional tests such as skin biopsy and genetic analysis were performed to exclude other possible causes such as atopic dermatitis, Langerhans histiocytosis, congenital ichthyosis, and psoriasis. Based on clinical presentation and additional test results, infantile seborrheic dermatitis seemed to be the most probable diagnosis. The treatment including 1% tannic acid, 0.5% erythromycin eye cream, clotrimazole cream, hydrocortisone cream, and emollients was started in the hospital with a good response. After a month of therapy, the patient was re-admitted for the follow-up, with further improvement of the skin condition. It is essential to remember that the dermatoses that we should take into consideration during the differential diagnosis of severe infantile seborrheic dermatitis are atopic dermatitis, Langerhans histiocytosis, congenital ichthyosis, and psoriasis.","PeriodicalId":112619,"journal":{"name":"Forum Dermatologicum","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135247413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A clinical and epidemiological retrospective analysis of patients with urticaria 荨麻疹患者临床及流行病学回顾性分析

Forum Dermatologicum Pub Date : 2023-09-29 DOI: 10.5603/fd.96508

Anna Stepaniuk, Aleksandra Morawska, Bartosz Pomichter, Jowita Karolina Gursztyn, Anna Baran, Iwona Flisiak

{"title":"A clinical and epidemiological retrospective analysis of patients with urticaria","authors":"Anna Stepaniuk, Aleksandra Morawska, Bartosz Pomichter, Jowita Karolina Gursztyn, Anna Baran, Iwona Flisiak","doi":"10.5603/fd.96508","DOIUrl":"https://doi.org/10.5603/fd.96508","url":null,"abstract":"Introduction: Urticaria is a heterogeneous disease which affects nearly 1 in 5 individuals in their lifetime and significantly worsens the quality of life. The aim of this study is a five-year retrospective analysis of epidemiological and clinical aspects of patients hospitalized for urticarial. Material and methods: Analysis of medical records of patients hospitalized for urticaria at the department of dermatology. The clinical and epidemiological data were analysed and compared to a control group composed of 137 healthy individuals’ body mass index (BMI) and sex-matched. Statistical analysis was performed using the chi-square test, a statistically significant difference was at p < 0.05. Results: In the analysed period 137 patients were hospitalized for urticaria, 93 females (68%) and 44 males (32%), with mean age 48.53. Thirty-eight per cent of patients have been previously diagnosed with an allergy. Over 60% of patients (60 women, 18 men) suffered from acute and 38% from chronic urticaria. A causal factor was identified in 62% of all cases, the most common were drugs (48%). Urticaria patients had significantly higher levels of C-reactive protein (CRP), neutrophils and glucose than controls (all p < 0.05). The patients were treated with antihistamines (94%), glucocorticosteroids (81%), and one patient was classified for omalizumab treatment. Conclusions: Urticaria still poses a challenge as the cause often remains unknown which highlights the need for novel diagnostic methods and interdisciplinary treatment. Recommended treatment includes antihistamines but among patients with chronic, treatment-resistant urticaria omalizumab should be considered.","PeriodicalId":112619,"journal":{"name":"Forum Dermatologicum","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135247409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psoriasis in the pediatric population: comorbidities with psoriasis 小儿牛皮癣:牛皮癣的合并症

Forum Dermatologicum Pub Date : 2023-09-29 DOI: 10.5603/fd.a2023.0011

Magdalena Szczegielniak, Aleksandra Lesiak, Joanna Narbutt

引用次数: 0

The potential role of Helicobacter pylori and other gut dysbiosis factors in the development of rosacea 幽门螺杆菌和其他肠道失调因素在酒渣鼻发展中的潜在作用

Forum Dermatologicum Pub Date : 2023-09-27 DOI: 10.5603/fd.96224

Zuzanna Luiza Frydrych, Natalia Chwarścianek, Karolina Błaszak, Rafał Czajkowski

引用次数: 0

Double trouble combat grenade allergic contact dermatitis 双重麻烦战斗手榴弹过敏性接触性皮炎

Forum Dermatologicum Pub Date : 2023-09-25 DOI: 10.5603/fd.96951

Agata Karny, Julia Nowowiejska, Julia Kobylińska, Zuzanna Panas, Anna Baran, Iwona Flisiak

引用次数: 0

Hereditary alpha tryptasemia: literature overview on the genetic trait and its clinical manifestations 遗传性α -色氨酸血症:遗传特征及其临床表现的文献综述

Forum Dermatologicum Pub Date : 2023-09-08 DOI: 10.5603/fd.96810

Agnieszka Rydz, Magdalena Lange

{"title":"Hereditary alpha tryptasemia: literature overview on the genetic trait and its clinical manifestations","authors":"Agnieszka Rydz, Magdalena Lange","doi":"10.5603/fd.96810","DOIUrl":"https://doi.org/10.5603/fd.96810","url":null,"abstract":"Hereditary Alpha Tryptasemia (HαT) is a genetic condition characterized by an increased number of copies of the TPSAB1 gene, resulting in elevated basal serum tryptase levels and an increased risk of anaphylaxis, especially in individuals with IgE-dependent allergies or systemic mastocytosis. The severity of clinical symptoms can vary and is influenced by the number of extra TPSAB1 gene copies, suggesting a gene-dose effect. Approximately two-thirds of individuals with HαT show minimal or no symptoms. The remaining individuals with HαT may present with Hymenoptera venom allergy, flushing, urticarial/angioedema, irritable bowel syndrome, gastrointestinal reflux, hypermobility, neuropsychiatric symptoms and dysautonomia. Recent studies revealed that α-tryptase which forms complexes with β-tryptase activate protease-activated receptor-2 (PAR2) receptors. Activation of these receptors may lead to hypotension, muscle contraction, inflammation, and trigger neuropeptide secretion, and in consequence, result in mast cell degranulation. This cycle of activation and degranulation may potentially contribute to the development of mast cell activation syndrome (MCAS). Mast cell activation syndromes are defined by systemic, severe and recurrent mast cell activations, usually in the form of anaphylaxis. Hereditary/ familial MCAS is a specific subtype of MCAS, which is associated with HαT. Diagnostic work-up for HαT includes determination of basal serum tryptase level and the presence of additional TPSAB1 gene copies using droplet digital polymerase chain reaction. Further research is needed, to explore the relationship between HαT and MCAS, as well as to determine if there is a distinct form of hereditary MCAS which is independent of HαT. These investigations aim to improve diagnostic approaches and treatment strategies for individuals with HαT, enhancing their management and overall quality of life.","PeriodicalId":112619,"journal":{"name":"Forum Dermatologicum","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136363419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0