The diagnosis and treatment of androgenetic alopecia: a review of the most current management

Karol Śliwa, Daria Synia, Waldemar Placek, Agnieszka Owczarczyk-Saczonek
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Abstract

Androgenetic alopecia is a widespread problem in contemporary dermatology, as it may also affect many young patients, in particular males, making them more prone to anxiety and depression which may be caused by a distorted body image. These behavioural problems may occur in older individuals as well. That is why, there is an obvious need for further development in that area of dermatology, which should also include discovering new therapies. In men, the diagnosis of androgenetic alopecia is quite simple, and the treatment usually involves incorporating minoxidil and/or finasteride. Switching from topical minoxidil to its systemic form as well as from finasteride to dutasteride may give better results in some patients. In general, male pattern hair loss (MPHL) is a chronic disease that may demand pharmacological treatment in the long term, which is often unlimited. Therefore, and also considering the patients’ concerns involving the systemic usage of 5α-reductase inhibitors as well as the limitations of current therapies, some specialists use topical finasteride, dutasteride in mesotherapy and many other additional modalities. When it comes to female pattern hair loss (FPHL), in most cases it is also a chronic entity, which especially in younger women demands performing extended lab testing in the search for potential hyperandrogenism. It is necessary to remember that especially in women the condition may be triggered by many environmental and other additional factors, so taking that into consideration may be helpful in some patients.
雄激素源性脱发的诊断和治疗:最新的管理回顾
雄激素性脱发在当代皮肤病学中是一个普遍的问题,因为它也可能影响许多年轻患者,特别是男性,使他们更容易焦虑和抑郁,这可能是由扭曲的身体形象引起的。这些行为问题也可能发生在老年人身上。这就是为什么皮肤病学领域明显需要进一步发展的原因,这也应该包括发现新的治疗方法。在男性中,雄激素源性脱发的诊断相当简单,治疗通常包括米诺地尔和/或非那雄胺。从局部米诺地尔到全身形式的转换,以及从非那雄胺到度他雄胺的转换,可能会给一些患者带来更好的结果。一般来说,男性型脱发(MPHL)是一种慢性疾病,可能需要长期的药物治疗,这往往是无限的。因此,考虑到患者对全身使用5α-还原酶抑制剂的担忧以及当前治疗方法的局限性,一些专家在美索疗法和许多其他方式中使用局部非那雄胺、度他雄胺。说到女性型脱发(FPHL),在大多数情况下,它也是一种慢性疾病,特别是在年轻女性中,需要进行大量的实验室测试,以寻找潜在的雄激素分泌过多症。有必要记住,尤其是女性,这种情况可能是由许多环境和其他额外因素引发的,所以考虑到这一点可能对一些患者有帮助。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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