{"title":"Guzkowe zapalenie tętnic — obraz kliniczny, diagnostyka i leczenie","authors":"M. Żychowska","doi":"10.5603/FD.A2020.0019","DOIUrl":"https://doi.org/10.5603/FD.A2020.0019","url":null,"abstract":"Polyarteritis nodosa (PAN) belongs to the group of medium vessel vasculitis. Two subtypes of the disease are classically distinguished — systemic variant and cutaneous variant. Systemic PAN is a potentially life-threatening disease, while cutaneous subtype is usually characterized by mild course. The review aims to summarize the symptomatology, diagnostics and treatment of PAN and to draw attention to the dermatological manifestations of the disease. Skin changes develop in 28–60% of patients with systemic PAN. The most common manifestations include palpable purpura, livedo reticularis and inflammatory nodules, and less commonly - urticarial lesions, transient erythema, distal necrosis, superficial phlebitis and splinter haemorrhages. Skin lesions in cutaneous PAN are typically located on the lower extremities, and less frequently — on the upper extremities or trunk. Painful nodules, livedo reticularis and ulcerations are the most frequent manifestations of cutaneous PAN. Ulcerations usually heal leaving ivory-white stellate scars ( atrophie blanche ) surrounded by telangiectasias. The diagnosis of both systemic and cutaneous subtype of the disease is based on diagnostic criteria. Management of systemic PAN consists of induction of remission and maintenance therapy. The choice of therapeutic option should be based on the severity of the disease and comorbidities, especially hepatitis B virus infection. Cutaneous PAN is characterized by a benign course with frequent relapses. First-line treatment usually consists of non-steroidal anti-inflammatory drugs, colchicine and dapsone. Considering frequent development of skin lesions in the course of PAN, knowledge of the clinical presentation, diagnosis and treatment of the condition is an important part of the everyday dermatological practice.","PeriodicalId":112619,"journal":{"name":"Forum Dermatologicum","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128830415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Choroby współistniejące z hidradenitis suppurativa","authors":"M. Sadowska, A. Lesiak, J. Narbutt","doi":"10.5603/fd.2019.0011","DOIUrl":"https://doi.org/10.5603/fd.2019.0011","url":null,"abstract":"Hidradenitis suppurativa (HS, acne inversa) is a chronic, inflammatory skin disease characterized by painful, inflamed lesions with a tendency to sinus formation and scarring, most commonly in the axillae, inguinal folds and anogenital area. It usually begins after puberty, more often in women, obese people and smokers. HS leads to a significant deterioration in the quality of life, its treatment is long-lasting and often does not bring the satisfactory results. Numerous studies indicate that HS may be associated with a variety of concomitant diseases. It has been shown that patients with hidradenitis suppurativa have an increased risk of developing obesity, diabetes, metabolic syndrome as well as inflammatory diseases (inflammatory bowel disease, autoinflammatory syndromes). An association of HS with depression, anxiety, spondyloarthropathies, including SAPHO syndrome, have also been observed. There are reports of the coexistance of HS with SCC and some reports have suggested an association between HS and congenital keratinization disorders, Down syndrome and Behcet’s disease. It is important to pay attention to the symptoms of these diseases in patients with HS, to enable their early detection and implementation of appropriate treatment.","PeriodicalId":112619,"journal":{"name":"Forum Dermatologicum","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125626762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Grzybica skóry twarzy imitująca krążkowy toczeń rumieniowaty","authors":"M. Niedźwiedź, M. Skibińska, A. Lesiak","doi":"10.5603/fd.2019.0010","DOIUrl":"https://doi.org/10.5603/fd.2019.0010","url":null,"abstract":"We present a case of a female with inflammatory lesions on the face which were clinically diagnosed as tinea. Topical antifungal treatment was not helpful and direct microscopy and later culture were negative. Incisional biopsy for histopathology was taken and the report revealed discoid lupus erythematosus. As topical corticosteroids and oral chloroquine did not improve the skin lesions, 40 mg daily of oral prednisone was introduced, causing worsening of the lesions. Tinea incognito was diagnosed empirically and the patient was treated with oral itraconazole. All skin lesions resolved within 2 weeks. The patient admitted that guinea pigs she owned at the time were under the care of a veterinarian due to skin lesions.","PeriodicalId":112619,"journal":{"name":"Forum Dermatologicum","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130936860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Demodekoza — podział, leczenie i występowanie u pacjentów z obniżonym poziomem odporności","authors":"M. Niedźwiedź, M. Skibińska","doi":"10.5603/fd.2019.0012","DOIUrl":"https://doi.org/10.5603/fd.2019.0012","url":null,"abstract":"Demodicosis is a skin disease of the pilosebaceous unit associated with Demodex folliculorum and Demodex brevis that involves mainly face and scalp. The role of the Demodex mites as agents in skin diseases remains controversial. They are commensal organisms; however, they are also thought to be pathogens in e.g. rosacea. A revised classification was proposed in 2014 dividing demodicosis into primary and secondary form. Secondary demodicosis can be diagnosed when in patients with inflammatory skin disorders or systemic diseases there is an abnormal increase of Demodex mites resulting in skin lesions. Perioral dermatitis, rosacea, seborrhoeic dermatitis, treatment with topical corticosteroids or calcineurin inhibitors are examples of those conditions. Secondary demodicosis is also associated with treatment with epidermal growth factor inhibitors, transplant patients, patients with malignancy, HIV infection, chronic renal failure, diabetes and during phototherapy treatment. Demodicosis should be considered as a differential diagnosis in immunocompromised patients.","PeriodicalId":112619,"journal":{"name":"Forum Dermatologicum","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115221751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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