Diagnostics最新文献

{"title":"Analysis and Characterization of Factors Affecting the Consistency of Tl-201 Myocardial Perfusion Single-Photon Emission Computed Tomography and Coronary Angiography Results in Patients with Suspected Coronary Artery Disease.","authors":"Fu-Ren Tsai, Hung-Pin Chan, Chun-Hao Yin, Jin-Shuen Chen, Yao-Shen Chen, Daniel Hueng-Yuan Shen","doi":"10.3390/diagnostics15121551","DOIUrl":"10.3390/diagnostics15121551","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Tl-201 myocardial perfusion single-photon emission computed tomography (MPS) is a minimally invasive test for patients with suspected coronary artery disease (CAD). While its predictive and prognostic values are well established, diagnostic performance varies. A recent meta-analysis reported that the sensitivity and specificity of MPS range from 48.8 to 100% and 46.7 to 94.7%, respectively, reflecting discordance between CAG. Little is known, however, about the influence of patients' characteristics and CAD risk factors on the diagnostic performance of MPS. This study aims to evaluate these factors in relation to MPS performance. <b>Methods</b>: We screened 4817 consecutive patients referred to our Nuclear Medicine Department in 2015 for Tl-201 MPS. Patients with clinically suspected ischemic heart disease who underwent CAG within 60 days post-MPS were included in the present analysis. The percentage of agreement/disagreement between the MPS-abnormal/normal and CAG-positive/negative groups was evaluated. Additionally, patient characteristics, CAD risk factors, co-morbidities, and single-photon emission computed tomography (SPECT) image-derived parameters were compared among the patients. <b>Results:</b> Among 635 patients with abnormal MPS, 583 had coronary stenosis. For the 52 without stenosis, causes included non-obstructive CAD (34.6%), prior infarction with scarring (32.7%), and imaging artifacts (32.7%). Significant stenosis was associated with older age, male sex, diabetes, dyslipidemia, CKD, and prior PCI, while hypertension and higher BMI were more common in insignificant CAD. Among 104 patients with normal MPS, 79 had stenosis, mainly in the LAD. Clinical risk factors were more prevalent in patients with any degree of stenosis. <b>Conclusions</b>: In patients with an abnormal MPS, the incorporation of visual interpretation, parameters, and CAD risk factors increases specificity and helps differentiate obstructive from non-obstructive CAD.</p>","PeriodicalId":11225,"journal":{"name":"Diagnostics","volume":"15 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mobile Phone Auscultation Accurately Diagnoses Chronic Obstructive Pulmonary Disease Using Nonlinear Respiratory Biofluid Dynamics.","authors":"Caroline Emily Gosser, Luther Daniel, Martin Huecker, Rodrigo Cavallazzi, Hiram Rivas, Jarred Jeremy Thomas, Ryan Close","doi":"10.3390/diagnostics15121550","DOIUrl":"10.3390/diagnostics15121550","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Chronic obstructive pulmonary disease (COPD) remains a condition with high morbidity, mortality, and misdiagnosis. The gold standard pulmonary function testing with spirometry has limited availability. This study seeks to test a novel diagnostic test based on auscultatory mapping of pulmonary dynamics. This NIH-funded study aimed to develop a COPD detection technology, using mobile phone auscultation, for situations in which spirometry is not available. <b>Methods:</b> This prospective study collected mobile phone auscultation data on patients presenting for spirometry and evaluation by a pulmonologist. All subjects had same-day or recent (less than 6 months) spirometry in one PFT laboratory. After informed consent, the subjects underwent respiratory auscultation using a selection of mobile phone brands. The auscultation methods included normal breathing observed at the left axillary site and egophony observed at the right supra clavicular fossa. The team created models from the recordings using Time Series Dynamics (TSD), proprietary software that uses computational nonlinear dynamics to characterize the respiratory biofluid dynamics implied by the acoustic data. <b>Results:</b> We enrolled a total of 108 patients (34.3% male), from 19 to 85 years of age (median 61 years). Among the patients, 64 (59.3%) subjects identified as White, 43 (39.8%) as Black, and 1 as Asian. Among the two cohorts with diverse comorbidities, 52 subjects had confirmed COPD and 56 did not. The cohorts differed significantly in age and body mass index, but not in race, number of comorbidities, or COPD assessment test scores. They had significant differences in forced expiratory volume in 1 s (FEV1), the FEV1/FVC (forced vital capacity) ratio, but not FVC. The recordings from the egophonic and axillary sites were initially modeled separately and then combined in a single composite model. The modeling produced excellent results with 90%+ AUC and sensitivity in both the test and train sets relative to the gold standard. <b>Conclusions:</b> Evidence suggests that a mobile phone auscultation device can accurately determine COPD diagnosis. In frontline applications where the availability of gold standard pulmonary function testing is limited, the device could improve the detection of COPD, a condition with significant over- and under-diagnosis. Future trials will investigate the ability of patients to self-record. Success would support remote COPD testing using transmitted telehealth recording data, bringing diagnosis to patients in underserved populations.</p>","PeriodicalId":11225,"journal":{"name":"Diagnostics","volume":"15 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anterior Tooth Inclination Between Skeletal Class II and III Malocclusions After Surgical Orthodontic Treatment.","authors":"Hiromi Tomaru, Chie Tachiki, Yu Nakamura, Dai Ariizumi, Satoru Matsunaga, Keisuke Sugahara, Akira Watanabe, Akira Katakura, Yasushi Nishii","doi":"10.3390/diagnostics15121553","DOIUrl":"10.3390/diagnostics15121553","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Anterior tooth inclination plays a critical role in treatment planning for surgical orthodontic cases. However, post-treatment outcomes in patients with jaw deformities often deviate from cephalometric values. This study aimed to compare anterior tooth inclination and skeletal morphology among patients with Class II and Class III malocclusions and to establish reference values for individualized treatment plans. <b>Methods</b>: A total of 122 patients (Class II: <i>n</i> = 40; Class III: <i>n</i> = 41; Class I: <i>n</i> = 41 as a control) were retrospectively analyzed. Cephalometric parameters, including U1 to FH and L1 to MP, were measured pre- and post-treatment. Group differences were analyzed using one-way ANOVA and Tukey's multiple comparison test. Multiple regression analysis was used to establish prediction models for anterior tooth inclination. The threshold for statistical significance was set at <i>p</i> < 0.05. <b>Results</b>: Post-treatment, upper anterior teeth were more lingually inclined in Class II patients and more labially inclined in Class III patients compared to Class I controls (U1 to FH: Class II, 106.8°; Class III, 120.4°; Class I, 111.1°; <i>p</i> < 0.01). Lower anterior teeth were more lingually inclined in Class III patients compared to Class I patients (L1 to MP: 84.9°; <i>p</i> < 0.01). Regression models demonstrated good predictive value (R² > 0.5) in non-extraction cases. <b>Conclusions</b>: Regression equations developed in this study, alongside the cephalometric averages of Class I individuals, may offer reliable reference values tailored to individual craniofacial morphology, contributing to optimized treatment planning in surgical orthodontic cases.</p>","PeriodicalId":11225,"journal":{"name":"Diagnostics","volume":"15 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agreement Between Bioelectrical Impedance Analysis and Ultrasound for Measuring Body Composition in Women with Breast Cancer.","authors":"Jared Rosenberg, Jyotsna Natarajan, David J Carpenter, Chris Peluso, Christie Hilton, Colin E Champ","doi":"10.3390/diagnostics15121545","DOIUrl":"10.3390/diagnostics15121545","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Higher percent body fat (BF) is associated with worse outcomes after treatment for breast cancer (BC). While ultrasound (US) imaging is a reliable method for analyzing body composition, it requires trained individuals for utilization. As such, bioelectrical impedance analysis (BIA) has been suggested as an alternative. Therefore, the goal of this study was to compare BIA with US. <b>Methods</b>: Women from three prospective exercise BC studies were analyzed with US and BIA before an exercise intervention. Spearman's correlation was used as a nonparametric measure to examine bivariate relationships between percent body fat measured by BIA and US. <b>Results</b>: In total, 106 women with BC had their body composition measured using both US and BIA. Despite a strong correlation between the two methods (r = 0.8, <i>p</i> < 0.01), US reported lower mean percent BF vs. BIA (34.6 ± 0.7% vs. 38.0 ± 0.8%, <i>p</i> < 0.01). In a subgroup analysis, concordance was seen in women with a body mass index below (BMI) ≤ 26 kg/m². BIA overreported percent BF compared to US in women with a BMI > 26 kg/m². <b>Conclusions</b>: In women with BC and BMI ≤ 26, US and BIA are in concordance when measuring BF. In women with a BMI > 26, BIA reports a higher BF than US. Overall, there was a strong correlation between modalities, while BMI can be used to guide the utilization of BIA as an alternative to US for assessing body composition.</p>","PeriodicalId":11225,"journal":{"name":"Diagnostics","volume":"15 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192121/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural and Hormonal Changes in Reproductive-Age Women Post-COVID-19: A Cross-Sectional Ultrasound and Biochemical Study.","authors":"Sandugash Yerkenova, Vyacheslav Lokshin, Almagul Kurmanova, Sharapat Moiynbayeva, Galiya Alikeyeva, Gulnara Kalibekova, Tamara Abdirova, Zamira Zhantenova, Kuralay Shaikova, Alla Mireeva, Aknur Turgumbayeva","doi":"10.3390/diagnostics15121536","DOIUrl":"10.3390/diagnostics15121536","url":null,"abstract":"<p><p><b>Background/Objectives:</b> The long-term impact of COVID-19 on female reproductive health remains poorly understood. This study aimed to assess structural and endocrine alterations in women of reproductive age who had recovered from SARS-CoV-2 infection compared to uninfected controls. <b>Materials and Methods:</b> A total of 150 women aged 18-45 years were enrolled in a comparative study: 75 with a confirmed history of COVID-19 and 75 without one. All participants underwent ultrasound examinations of their pelvic organs and mammary glands, along with laboratory assessment of reproductive hormones and inflammatory markers. <b>Results:</b> Structural abnormalities in the pelvic organs were observed in 53.5% of the post-COVID-19 group versus 12.0% of the control group (<i>p</i> < 0.001), with oophoritis showing a statistically significant association (OR = 11.38; 95% CI: 1.42-91.36; <i>p</i> = 0.009). Non-significant but elevated frequencies were also found for uterine fibroids and breast cysts. Biochemically, post-COVID-19 participants demonstrated higher serum ferritin, estradiol, and fibrinogen levels, along with lower TSH and AMH levels, suggesting potential endocrine disruption and persistent inflammation. <b>Conclusions:</b> Women with a history of COVID-19 may be at increased risk of developing structural and hormonal abnormalities, highlighting the importance of post-infection gynecological and endocrine monitoring. Further longitudinal studies are required to elucidate the long-term effects and underlying mechanisms of these alterations.</p>","PeriodicalId":11225,"journal":{"name":"Diagnostics","volume":"15 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical Lipomatous Tumours vs. Lipomas: A Multimodal Diagnostic Approach.","authors":"Wolfram Weschenfelder, Katharina Lucia Koeglmeier, Friederike Weschenfelder, Christian Spiegel, Amer Malouhi, Nikolaus Gassler, Gunther Olaf Hofmann","doi":"10.3390/diagnostics15121538","DOIUrl":"10.3390/diagnostics15121538","url":null,"abstract":"<p><p><b>Background/Objectives</b>: This study aimed to develop a reliable scoring system combining clinical and radiological parameters to distinguish atypical lipomatous tumours (ALTs) from lipomas, improving diagnostic accuracy and reducing expensive molecular pathology testing. <b>Methods</b>: A retrospective analysis of 188 patients who underwent surgery for lipomatous tumours was conducted. Patient data, including medical history, pathology, and MRI imaging results, were reviewed. Four predictive models were developed using various clinical and imaging parameters, including age, tumour size, location, and MRI characteristics (homogeneity, contrast enhancement). Statistical analysis, including ROC curve analysis and logistic regression, was performed to assess the accuracy of these models. <b>Results</b>: The highest predictive accuracy was achieved with Model 1, which included seven parameters, yielding an AUC of 0.952. This model achieved a sensitivity of 96.4% and a negative predictive value (NPV) of 97.2%. Reducing the number of parameters lowered the accuracy, with contrast enhancement playing a significant role in Model 1. A risk calculator based on the optimal model was developed, offering an effective tool for clinical use that can be provided. Notably, 21 out of 37 ALTs lacked atypia and would have been missed without molecular testing. <b>Conclusions</b>: The developed scoring system, based on clinical and imaging parameters, accurately distinguishes ALTs from lipomas, offering a practical alternative to molecular pathology testing. This multi-parameter approach significantly improves diagnostic reliability, reducing the risk of misclassification and false negatives, while also potentially lowering healthcare costs.</p>","PeriodicalId":11225,"journal":{"name":"Diagnostics","volume":"15 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Importance of Magnetic Resonance Enterography in Monitoring Inflammatory Bowel Disease: A Review of Clinical Significance and Current Challenges.","authors":"Roxana Elena Mirică, Teodora Florentina Matură, Eliza Craciun, Dana Pavel","doi":"10.3390/diagnostics15121540","DOIUrl":"10.3390/diagnostics15121540","url":null,"abstract":"<p><p>Inflammatory bowel diseases are chronic diseases of the gastrointestinal tract with a growing prevalence worldwide, requiring precise diagnostic and monitoring methods to guide their appropriate treatment. In this context, MRE (Magnetic Resonance Enterography) has become an essential imaging technique as a non-invasive option for the diagnosis of Crohn's disease and ulcerative colitis in recent years. This method provides detailed information about intestinal inflammation, disease activity, complications, and response to therapy, without the need to expose the patient to ionizing radiation. This study analyzes the advantages of MRE over other imaging methods, as well as its clinical applicability and current challenges. We also discuss future perspectives, including the integration of artificial intelligence and the optimization of protocols for better diagnostic accuracy.</p>","PeriodicalId":11225,"journal":{"name":"Diagnostics","volume":"15 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic Resonance Imaging of Submental and Masticatory Muscle Morphology and Its Relationship with Temporomandibular Joint Structures.","authors":"Melisa Öçbe, Mahmut Sabri Medişoğlu","doi":"10.3390/diagnostics15121535","DOIUrl":"10.3390/diagnostics15121535","url":null,"abstract":"<p><p><b>Introduction</b>: This study aimed to evaluate the submental and masticatory muscles in patients of different age groups using magnetic resonance imaging (MRI) and computed tomography (CT) methods, and investigate potential associations between muscle morphology, temporomandibular joint (TMJ) structures, and disc displacement. <b>Materials and Methods</b>: A total of 185 MRI scans were retrospectively analyzed to assess the thickness of the digastric, geniohyoid, mylohyoid, medial pterygoid, masseter, and lateral pterygoid muscles bilaterally. TMJ hard tissue changes were classified using computed tomography (CT). Correlations between muscle thickness and TMJ structures were analyzed using Pearson correlation coefficients, with statistical significance set at <i>p</i> < 0.05. <b>Results</b>: The study population included 110 females and 75 males, with a mean age of 50.08 ± 20.15 years. The largest age group was 51-75 years (41%), followed by 18-35 years (28%). Significant correlations were observed between muscle thickness and TMJ structures as follows: Right digastric muscle showed a significant association with right disc-condyle position (<i>p</i> = 0.02). Right mylohyoid muscle exhibited a strong correlation with right disc-condyle position (<i>p</i> = 0.004). Left medial pterygoid muscle was significantly correlated with left condyle pathology (<i>p</i> = 0.02). Left masseter muscle showed a significant correlation with left condyle pathology (<i>p</i> = 0.014). Condylar flattening was the most frequent pathology, observed in 58% of right condyles and 53% of left condyles. Disc displacement was present in 41% of right TMJs and 34% of left TMJs. <b>Conclusions</b>: This study highlights the important associations between masticatory and submental muscle morphology and TMJ structures, suggesting that muscle function may play a role in condylar positioning and disc alignment. These findings emphasize the need for comprehensive muscle evaluation in TMJ disorder (TMD) diagnosis and treatment planning.</p>","PeriodicalId":11225,"journal":{"name":"Diagnostics","volume":"15 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When a Lump Is Not a Cyst: A Case of Superficial Venous Aneurysm of the Hand Diagnosed with High-Resolution Ultrasound.","authors":"Antonio Corvino, Orlando Catalano, Corrado Tagliati, Giulio Cocco, Domenico Tafuri, Fabio Corvino, Marco Fogante, Oriana Simonetti","doi":"10.3390/diagnostics15121546","DOIUrl":"10.3390/diagnostics15121546","url":null,"abstract":"<p><p>Superficial venous aneurysms of the upper extremities are a rare clinical entity, often underdiagnosed and misinterpreted as other soft tissue masses. We present the case of a 28-year-old male patient with a subcutaneous mass on the dorsum of the left hand, diagnosed as a superficial venous aneurysm by high-resolution ultrasound using a probe bandwidth of up to 18 MHz, unchanged at three-month Doppler-ultrasound examination. This case highlights the fundamental role of high-frequency ultrasound in the differential diagnosis and conservative management of such lesions.</p>","PeriodicalId":11225,"journal":{"name":"Diagnostics","volume":"15 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine and Deep Learning for the Diagnosis, Prognosis, and Treatment of Cervical Cancer: A Scoping Review.","authors":"Blanca Vazquez, Mariano Rojas-García, Jocelyn Isabel Rodríguez-Esquivel, Janeth Marquez-Acosta, Carlos E Aranda-Flores, Lucely Del Carmen Cetina-Pérez, Susana Soto-López, Jesús A Estévez-García, Margarita Bahena-Román, Vicente Madrid-Marina, Kirvis Torres-Poveda","doi":"10.3390/diagnostics15121543","DOIUrl":"10.3390/diagnostics15121543","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Cervical cancer (CC) is the fourth most common cancer among women worldwide. This study explored the use of machine learning (ML) and deep learning (DL) in the prediction, diagnosis, and prognosis of CC. <b>Methods:</b> An electronic search was conducted in the PubMed, IEEE, Web of Science, and Scopus databases from January 2015 to April 2025 using the search terms ML, DL, and uterine cervical neoplasms. A total of 153 studies were selected in this review. A comprehensive summary of the available evidence was compiled. <b>Results:</b> We found that 54.9% of the studies addressed the application of ML and DL in CC for diagnostic purposes, followed by prognosis (22.9%) and an incipient focus on CC treatment (22.2%). The five countries where most ML and DL applications have been generated are China, the United States, India, Republic of Korea, and Japan. Of these studies, 48.4% proposed a DL-based approach, and the most frequent input data used to train the models on CC were images. <b>Conclusions:</b> Although there are results indicating a promising application of these artificial intelligence approaches in oncology clinical practice, further evidence of their validity and reproducibility is required for their use in early detection, prognosis, and therapeutic management of CC.</p>","PeriodicalId":11225,"journal":{"name":"Diagnostics","volume":"15 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}