Current Pediatric Research最新文献

{"title":"Thoracoscopic clipping of open ductus arteriosus in premature infants: Progress in neonatal surgery.","authors":"Khatamov Furkhat, Kemelbekov Kanatzhan, Ku, ykov Yerlan, Musaev Yuldash, Zhumabekov Zharylkap, Bekenov Nurlan, M. Gatauova, Abdrakhmanovazinat, Omarova Balnur, Makhatova Venera","doi":"10.35841/0971-9032.25.5.472-478","DOIUrl":"https://doi.org/10.35841/0971-9032.25.5.472-478","url":null,"abstract":"Currently, the closure cap used: open surgery, endovascular occlusion and thoracoscopic clipping of OAD. A special group of children are immature, premature children who are on artificial ventilation associated with persistent fetal circulation. The study analyzed the medical history of 97 premature newborns with this heart defect, which were in the \"Regional perinatal center\" of Zhambyl region in the period 2015-2019. On the basis of complex clinical and instrumental studies, the newborns were divided into groups according to gestational age, weight and dependence on the features of the open arterial duct. The results of surgical treatment were analyzed, identified risk factors and possible complications.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"25 1","pages":"472-478"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70027950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of levetiracetam and sodium valproate monotherapy in childhood epilepsy-An open label randomized trial","authors":"Swati Bhayana, A. Aggarwal, M. Narang, Sangeeta Sharma, R. Malhotra","doi":"10.35841/0971-9032.357-361","DOIUrl":"https://doi.org/10.35841/0971-9032.357-361","url":null,"abstract":"Objectives: To compare the efficacy of oral levetiracetam and valproate in childhood epilepsy by comparing number of repeat seizures for 6 months, side effect profile, retention rates and time to first seizure. Setting-The study was conducted in tertiary care hospital of North India. Participants-Hundred children, 3-12 years of newly diagnosed epilepsy (generalised or focal motor). Intervention-Children were randomly allocated to receive oral valproate or levetiracetam in a dose of 20 mg/kg/day after initial loading dose (n=50 in each group). Drug levels were estimated by ELISA method at steady state, end of therapy and in case of any seizure activity. Side effect and repeat seizures were recorded till 6 months. Outcome measures-No repeat seizure activity for 6 months, side effect profile, achievement of therapeutic drug levels at steady state and 6 months were studied. Results: Two groups were comparable in basic demographic data. In 6 months, 8 children in valproate group and 12 in levetiracetam gr oup had r epeat seizur e (p=0.317). Mean time to first seizur e was similar in two groups (p=0.930). Mean survival time was 145.16(127.39 ± 162.93) days with levetiracetam and 159.80(145.77 ± 173.82) with valproate. The hazard ratio of valproate for treatment failure was lower. There was 38% more reduction in hazard of treatment failure with valproate compared to levetiracetam though not statistically significant (p=0.297). Overall side effects were comparable (p=0.341). Behavioural side effects were significantly more with levetiracetam (p=0.021). Conclusion: First line therapy with oral levetiracetam or valproate is comparable in efficacy and side effects in childhood epilepsy.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"1 1","pages":"357-361"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70028269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precocious puberty and hypertension secondary to testicular tumor in a Nigerian boy: Case report.","authors":"Oyedeji Oa, I. Oluwayemi, E. Adeniji, Akintola Am, T. Ayeni, Bayode Ao, Adekunle Og, AdebimpeAfolabi Aa","doi":"10.35841/0971-9032.25.6.623-626","DOIUrl":"https://doi.org/10.35841/0971-9032.25.6.623-626","url":null,"abstract":"Precocious puberty is an uncommon cosmopolitan disease, characterized by attainment of secondary sexual characteristics before the age norm for sex. Reports of precocious puberty with attendant hypertension are rare. Detection of the cause of hypertension and precocious puberty which can be central or peripheral is a prerequisite for institution of appropriate management. The outcome of the time, resources and efforts expended in obtaining care for this condition is dependent on the knowledge and expertise of the health care provider. Other determinants of outcome include the understanding of the minor concerned, the parental skills and parental resources. We present an 8 year old Nigerian boy with features of precocious puberty and hypertension. We highlight the not so desirable outcome and challenges associated with previous and current management of this patient. Hopefully, this report will increase awareness on this condition and improve management practices amongst health practitioners in similar settings.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"25 1","pages":"623-626"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70028170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short stature in transfusion dependant beta thalassemia children.","authors":"Jagroop Singh Sangha, Prabhpreet Kaur Sira","doi":"10.35841/0971-9032.25.8.725-728","DOIUrl":"https://doi.org/10.35841/0971-9032.25.8.725-728","url":null,"abstract":"Background: Due to high prevalence of beta thalassemia in North India, we conduct this study to assess the prevalence of short stature in such cases. Objective: Study the prevalence of short stature in transfusion dependant beta thalassemia in children aged 5 years-18 years and its correlation with transfusion frequency. Materials and Methods: This is a cross sectional study performed at pediatrics department, government medical college, and Patiala included 93 cases of transfusion dependant beta thalassemia. Anthropometric data was recorded and height of every child was plotted on Indian academy of pediatrics 2015 growth charts. Short stature defined as height less than 3rd percentile. Data were collected, managed, edited, entered, and analyzed by Statistical Package of Social Sciences (SPSS) software. Receiver operating curve was analyzed for frequency of transfusion and short stature. The level of significance taken for the entire statistical test was a P-value of <0.05. Results: 64 males and 29 females were included aged 5 years-18 years with mean age of 10.09 ± 3.4 years. 41 (44.1%) cases were short stature, including 33 (80.5%) males and 8 (19.5%) females. Mean age of short stature cases was 11.9 ± 2.9 years compared to 8.6 ± 3.1 years in cases with normal height (p-value<0.05). ROC curve between short stature and transfusion frequency showed cut off of 16 days. We observed a significant correlation between frequency of transfusion and the incidence of short stature (P=0.001). Conclusion: Short stature is highly prevalent among multi-transfused beta thalassemia children and hence it is recommended that every patient should be sort out for short stature.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"25 1","pages":"725-728"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70028632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal reflexive functions and parent training in children with oppositional defiant disorder.","authors":"A. Frolli, E. Saviano, F. DiCarmine, I. Lapenna, M. Carotenuto, Ricci Mc","doi":"10.35841/0971-9032.25.8.744-751","DOIUrl":"https://doi.org/10.35841/0971-9032.25.8.744-751","url":null,"abstract":"Oppositional Defiant Disorder (ODD) is one of the most common neuropsychiatric disorders in preschool children. Parental self-regulation is critical for maintaining positive parenting practices. However, to the best of our knowledge, existing parental trainings for ODD do not focus on the enhancement of parental reflective functions. In the present study, we compare two models of behavioral Parent Training (PT) for duration of six months: one, already consolidated, is based on the principles of Applied Behavioral Analysis (ABA), the other, innovative, integrates with the model of the regulatory and reflective parental function of Fonagy. Outcomes revealed that the innovative training was more effective as compared to the ABA training shopping that an improvement into the ability of parents to imagine the subjective experience of their developing children increases the development of children's self-regulation.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"2 2 1","pages":"744-751"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70028684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of S.T.I.C.K bundle for the prevention of IV Infiltration rate in the terms of practice among staff nurses working in tertiary care hospital Bhubaneswar, Odisha.","authors":"Debasruti Bhunia, N. Das, P. Sahoo","doi":"10.35841/0971-9032.25.3.436-442","DOIUrl":"https://doi.org/10.35841/0971-9032.25.3.436-442","url":null,"abstract":"Intravenous (IV) fluid and medication infiltrations may result in serious complications such as tissue necrosis, ulcerations, and compartment syndromes. Objectives are to assess the existing and postpractice level skills of staff nurses about the S.T.I.C.K. Bundle and to find out the effectiveness of bundle in terms of improvement in posttest level of practice scores. Research approach was quantitative research approach and research design was pre experimental one group pretest-posttest design. Sample size was 30 and sampling technique was non probability consecutive sampling. Major finds were apparently higher in the post test group in comparison to the pre-test group. The paired ‘t’ test value is found to be 2.16 at the degree of freedom 29 and the corresponding p value is <0.05. Hence, the research hypothesis can be accepted at 5% level of significance and can be inferred that there is significant difference between pre and post-practice level.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"25 1","pages":"436-442"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70027268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum zinc changes in term neonates with hyperbilirubinemia after phototherapy","authors":"Aida A Manthar","doi":"10.4172/456","DOIUrl":"https://doi.org/10.4172/456","url":null,"abstract":"Background: Neonatal jaundice occurs due to the elevated levels of unconjugated bilirubin and may induce neurological sequelae, such as encephalopathy. Phototherapy remains the main primary management in neonatal jaundice; one of its effects is elevated in zinc level. Objectives: Assess serum zinc level in full term neonates who had hyperbilirubinemia and treated by phototherapy before and after phototherapy and study it`s relation to selected neonatal, maternal and labour factors. Methods: A prospective study has been carried out in Basrah Maternity and Children Hospital, 2nd neonatal care unit to assess serum zinc on 60 term neonates appropriate for gestational age with unconjugated hyperbilirubinemia treated by phototherapy. Neonatal, maternal data were collected, serum zinc was assessed before and after phototherapy, (normal range: 50-150 μg/dL), elevated in serum zinc was studied in relation to selected variables. Results: It was found that total serum bilirubin was lower after phototherapy and serum zinc was elevated. The result is statistically significant. Elevated serum zinc was found in 33.3% of cases. It was more in in extensive phototherapy than double or single. P value < 0.05. Also, more with prolonged period of phototherapy but the result was statistically not significant. It was not related to other neonatal or maternal characters. Conclusion: Serum zinc is elevated after phototherapy in neonates with hyperbilirubinemia, increase level is more with use of extensive phototherapy and increase level of total serum bilirubin.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"40 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70318524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performing sound imitation in differentiating stridor and wheezing inclinical practice","authors":"Nasser S Alharbi, Dana Al-Enezi, Alwalid Alteraif","doi":"10.35841/0971-9032.25.1.334-336","DOIUrl":"https://doi.org/10.35841/0971-9032.25.1.334-336","url":null,"abstract":"Noisy breathing is a common symptom of respiratory illnesses; wheezing and stridor are common sounds that need to be clarified during assessment of children with history of recurrent attacks of noisy breathing. The answers of non-english speaking families can be influenced by the used words to express wheezing and stridor in their language. The primary outcome of this survey based study is to assess if the sounds imitation of wheezing and stridor is a common practice by Arabic speaking pediatricians while assessing children with noisy breathing. A hundred fifty two arabic speaking pediatricians participated. Almost 25% and 5% of Arabic speaking pediatricians use sound imitation to express stridor and wheezing (respectively). Mainly due to their inability to express stridor/ wheezing in Arabic language, variable Arabic words are used to express both sounds interchangeably. The pediatricians have a major language barrier to express stridor and wheezing to their original language, sound imitation of both sounds is common practice and we suggest that it improves the communication between pediatricians and families.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"25 1","pages":"334-336"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70026867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary imaging findings in young infants with bacteremic urinary tractinfection.","authors":"Fatma S. Alzhrani, Fayza Al Siny, Yaser S Bamshmous, Sarah Radwan, Bashair Alotaibi, Haneen S. Almalki, Dhuha A. Alhumaidi","doi":"10.35841/0971-9032.25.2.328-330","DOIUrl":"https://doi.org/10.35841/0971-9032.25.2.328-330","url":null,"abstract":"Background: The Urinary Tract Infection (UTIs) is one of the most widely acquired bacterialinfections in infants. UTI sometimes accompanied by bacteremia. Bacteremia is characterising as thedevelopment of a pathogen within the blood culture. Imaging tests, such as a Renal Ultrasound (RUS)and Avoiding Cystourethrogram (VCUG) use to diagnose UTIs. Aim: We aimed to describe RUS and VCUG findings in young infants with bacteremic urinary tractinfection and to determine the association between imaging findings and other variables at a tertiaryhospital in Jeddah, Saudi Arabia. Methods: We retrospectively studied the medical records of 30 infants from both genders who haddiagnosed with bacteremic UTIs at a tertiary hospital in Jeddah, Saudi Arabia. Infants were excludedif they had known urologic abnormalities at the time of presentation, required intensive unite care andinfants with immunocompromised diseases. Data was analyzed by SPSS program. Results: Of the 30 infants, 70% were boys, 50% aged from 0-3 months while the other 50% aged >3months, 14 (46.7%) were Saudis while 16 (53.3%) were non-Saudis, 61.1% were non-febrile, 58.62%had standard creatinine value. All infants 100% underwent RUS, 96.2% of them had RUSabnormalities (18 males and seven females) while only 3.8% (1 male) had typical RUS result. 37.9% ofinfants underwent VCUG, 18.2% (2 miles) of them had normal VCUG, while the majority 81.8% (7males and two females) had abnormal findings. 17.9% presented with VUR. There was no significantassociation between RUS results with sex, age group, creatinine value and urine cultures. On anotherhand, there was a significant association between RUS abnormal result and blood culture. Also, nosignificant association found between VCUG results with sex, age group, creatinine, blood and urinecultures. Conclusion: In conclusion, the prevalence of RUS and VCUG abnormality in our cohort found to behigher than other studies. There was a significant association between RUS finding and blood cultureresults; on another hand, there was no significant association between RUS and VCUG findings withother variables that could suggest bacteremic risk in UTI infants.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"25 1","pages":"328-330"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70027504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications of microdebrider assisted endoscopic adenoidectomy.","authors":"M. Jaber","doi":"10.35841/0971-9032.25.6.627-630","DOIUrl":"https://doi.org/10.35841/0971-9032.25.6.627-630","url":null,"abstract":"Background: The adenoid is part of lymphoid tissue called Waldeyer’s ring. Pathological effects include rhinitis, rhino sinusitis, otitis media and otitis media with effusion. Failure of medical therapy in these conditions may need surgical intervention. Adenoidectomy is one of the most common surgical procedures in children, but many complications can occur as bleeding, velopharyngeal incompetence, and re growth of the adenoid. Aim of the study: To assess the complications of microdebrider assisted endoscopic adenoidectomy. Methods: This study is a prospective in natureconsisted of 100 patients. They were 55 males and 45 females. They had been assessed at the Al-Diwaniah Teaching Hospital, Al-Diwaniah city, Iraq, during the period of March 2017 to January 2020, the age ranges from 5-15 years. An inclusion criterion is adenoid hypertrophy causing one or more of the following: nasal obstruction, recurrent upper respiratory tract infections, recurrent acute otitis media, otitis media with effusion, or sleep apnea, not responding to adequate conservative therapy. Exclusion criteria are: small asymptomatic adenoid, bleeding tendency, patient required tonsillectomy and patient with craniofacial anomalies as cleft palate. All the patients had microdebrider assisted endoscopic adenoidectomy. Results: The post-operative pain was mild, reactionary haemorrhage recorded in 3 patients while secondary haemorrhage was not recorded. 2 patients developed adenoid recurrence. 1 patient developed nasopharyngeal blood clot. Infection occurred in 2 patients. Velopharyngeal incompetence occurred in 3 patients. Eustachian tube injury occurred in only 1 patient. Conclusion: Microdebrider Assisted Endoscopic Adenoidectomy (MAEA) provides direct visualization and controlled surgery so it is safe and decrease the rate of complications, and can be carried as day case surgery.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"25 1","pages":"627-630"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70028212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}