Current Pediatric Reviews最新文献

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A Narrative Review on Diabetic Ketoacidosis in Children. 关于儿童糖尿病酮症酸中毒的叙述性综述。
IF 2
Current Pediatric Reviews Pub Date : 2024-01-31 DOI: 10.2174/0115733963276045240123154733
Karen K Y Leung, Joanna Y L Tung, Yan Tung Kelly Lee, Stephanie Tsang, Kam Lun Hon
{"title":"A Narrative Review on Diabetic Ketoacidosis in Children.","authors":"Karen K Y Leung, Joanna Y L Tung, Yan Tung Kelly Lee, Stephanie Tsang, Kam Lun Hon","doi":"10.2174/0115733963276045240123154733","DOIUrl":"https://doi.org/10.2174/0115733963276045240123154733","url":null,"abstract":"<p><strong>Background: </strong>Diabetic ketoacidosis (DKA) is a life-threatening complication in children with diabetes mellitus. There are considerable differences in the management approaches for DKA between different countries. One of the main areas of differences between guidelines is the administration of fluid, with most guidelines adopting a restrictive approach. This is based on the concern over cerebral oedema, a lethal sequela allegedly to be caused by excessive fluid administration. However, in recent years, new clinical studies suggest that there is no causal relationship between intravenous fluid therapy and DKA-related cerebral injury. The British Society of Paediatric Endocrinology updated its guideline in 2020 to adopt a more permissive approach to fluid administration, which has sparked controversy among some paediatricians.</p><p><strong>Objectives: </strong>The purpose of this article is to provide a narrative review on the management of DKA.</p><p><strong>Methods: </strong>A PubMed search was performed with clinical queries using the key term \"diabetic ketoacidosis\". The search strategy included randomized controlled trials, clinical trials, meta-analyses, observational studies, guidelines, and reviews. The search was restricted to English literature and the age range of 18 years and younger. Moreover, we reviewed and compared major guidelines.</p><p><strong>Conclusion: </strong>The management of DKA involves early recognition, accurate diagnosis, meticulous fluid and insulin treatment with close monitoring of blood glucose, ketones, electrolytes, renal function, and neurological status. There is still limited clinical evidence to support either a restrictive or permissive approach in the fluid management of paediatric DKA patients. Clinicians should exercise caution when applying different guidelines in their clinical practice, considering the specific circumstances of individual paediatric patients.</p>","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139650449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iodine Status in Cyprus and Neighboring Countries: A Review Article. 塞浦路斯及其邻国的碘状况:评论文章。
IF 2
Current Pediatric Reviews Pub Date : 2024-01-30 DOI: 10.2174/0115733963275007231227051736
Nese Akcan, Ismet Zaimagaoglu
{"title":"Iodine Status in Cyprus and Neighboring Countries: A Review Article.","authors":"Nese Akcan, Ismet Zaimagaoglu","doi":"10.2174/0115733963275007231227051736","DOIUrl":"https://doi.org/10.2174/0115733963275007231227051736","url":null,"abstract":"<p><p>Despite the implementation of global iodine supplementation initiatives in the past decade, the problem of iodine deficiency persists as a significant public health concern in numerous countries. Although cretinism is now rare in developed countries, iodine deficiency can still lead to less severe cognitive deficits, which can negatively impact academic achievement, intellectual capacity, and work productivity. There is a scarcity of studies regarding the status of Cyprus, and the global database does not have any information pertaining to the prevalence of iodine deficiency in Cyprus. The geographical setting of the research is of importance as it pertains to the separation of Cyprus into two distinct areas. One region is predominantly inhabited by Greek Cypriots, where the practice of salt iodization is not mandatory. Conversely, the other region is primarily inhabited by Turkish Cypriots, who may potentially experience higher amounts of iodine contact due to their reliance on food imports from Turkey, where salt-iodisation is compulsory. The main objective of this study is to provide an overview of recent research conducted on the prevalence of iodine deficiency in Cyprus and neighboring Mediterranean nations. In this study, we assess the current method and subsequently offer public health recommendations for future research endeavors.</p>","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139650450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insights from Overviewing Selective International Guidelines for Pediatric Asthma. 选择性国际儿科哮喘指南概览》的启示。
IF 2
Current Pediatric Reviews Pub Date : 2024-01-29 DOI: 10.2174/0115733963270829231221062201
Kam Lun Ellis Hon, Daniel K K Ng, Wa Keung Chiu, Alexander K C Leung
{"title":"Insights from Overviewing Selective International Guidelines for Pediatric Asthma.","authors":"Kam Lun Ellis Hon, Daniel K K Ng, Wa Keung Chiu, Alexander K C Leung","doi":"10.2174/0115733963270829231221062201","DOIUrl":"https://doi.org/10.2174/0115733963270829231221062201","url":null,"abstract":"<p><strong>Background: </strong>Asthma is a chronic atopic and inflammatory bronchial disease characterized by recurring symptoms and, episodic reversible bronchial obstruction and easily triggered bronchospasms. Asthma often begins in childhood. International guidelines are widely accepted and implemented; however, there are similarities and differences in the management approaches. There is no national guideline in many cities in Asia. This review aims to provide a practical perspective on current recommendations in the management of childhood asthma, specifically in the following aspects: diagnosis, classification of severity, treatment options, and asthma control, and to provide physicians with up-to-date information for the management of asthma.</p><p><strong>Methods: </strong>We used the PubMed function of Clinical Queries and searched keywords of \"Asthma\", \"Pediatric,\" AND \"Guidelines\" as the search engine. \"Clinical Prediction Guides\", \"Etiology\", \"Diagnosis\", \"Therapy,\" \"Prognosis,\" and \"Narrow\" scope were used as filters. The search was conducted in November 2022. The information retrieved from this search was used in compiling the present article.</p><p><strong>Results: </strong>Diagnosis is clinically based on symptom pattern, response to therapy with bronchodilators and inhaled corticosteroids, and spirometric pulmonary function testing (PFT). Asthma is classified in accordance with symptom frequency, peak expiratory flow rate (PEFR), forced expiratory volume in one second (FEV1), atopic versus nonatopic etiology, where atopy means a predisposition toward a type 1 hypersensitivity reaction. Asthma is also classified as intermittent or persistent (mild to severe). Unfortunately, there is no disease cure for asthma. However, symptoms can be prevented by trigger avoidance and suppressed with inhaled corticosteroids. Antileukotriene agents or long-acting beta-agonists (LABA) may be used together with inhaled corticosteroids if symptoms of asthma are not controlled. Rapidly worsening symptoms are usually treated with an inhaled short-acting beta-2 agonist (SABA, e.g., salbutamol) and oral corticosteroids. Intravenous corticosteroids and hospitalization are required in severe cases of asthma attacks. Some guidelines also provide recommendations on the use of biologics and immunotherapy.</p><p><strong>Conclusion: </strong>Asthma is diagnosed clinically, with supporting laboratory testing. Treatment is based on severity classification, from intermittent to persistent. Inhaled bronchodilator and steroid anti-inflammatory form the main stay of management.</p>","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139574990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pinworm (Enterobius Vermicularis) Infestation: An Updated Review. 蛲虫(Enterobius Vermicularis)感染:最新综述。
IF 2
Current Pediatric Reviews Pub Date : 2024-01-28 DOI: 10.2174/0115733963283507240115112552
Alexander K C Leung, Joseph M Lam, Benjamin Barankin, Alex H C Wong, Kin Fon Leong, Kam Lun Hon
{"title":"Pinworm (Enterobius Vermicularis) Infestation: An Updated Review.","authors":"Alexander K C Leung, Joseph M Lam, Benjamin Barankin, Alex H C Wong, Kin Fon Leong, Kam Lun Hon","doi":"10.2174/0115733963283507240115112552","DOIUrl":"10.2174/0115733963283507240115112552","url":null,"abstract":"<p><strong>Background: </strong>Pinworm infestation is an important public health problem worldwide, especially among children 5 to 10 years of age in developing countries with temperate climates. The problem is often overlooked because of its mild or asymptomatic clinical manifestations.</p><p><strong>Objective: </strong>The purpose of this article was to familiarize pediatricians with the diagnosis and management of pinworm infestation.</p><p><strong>Methods: </strong>A search was conducted in August 2023 in PubMed Clinical Queries using the key terms \"Enterobius vermicularis,\" OR \"enterobiasis,\" OR \"pinworm.\" The search strategy included all clinical trials, observational studies, and reviews published within the past 10 years. Only papers published in the English literature were included in this review. The information retrieved from the above search was used in the compilation of the present article.</p><p><strong>Results: </strong>Enterobiasis is a cosmopolitan parasitosis caused by Enterobius vermicularis. It affects approximately 30% of children worldwide and up to 60% of children in some developing countries. Predisposing factors include poor socioeconomic conditions, inadequate sanitation, poor personal hygiene, and overcrowding. Children aged 5 to 14 years have shown the highest prevalence of enterobiasis.. Egg transmission is mainly by the fecal-oral route. Approximately 30 to 40% of infested patients do not show any clinical symptoms of the disease. For symptomatic patients, the most common presenting symptom is nocturnal pruritus ani. The diagnosis of E. vermicularis infection is best established by the cellophane tape test. The sensitivity of one single test is around 50%; however, the sensitivity increases to approximately 90% with tests performed on three different mornings. If a worm is visualized in the perianal area or the stool, a pathological examination of the worm will yield a definitive diagnosis. As pinworms and eggs are not usually passed in the stool, examination of the stool is not recommended. The drugs of choice for the treatment of pinworm infestation are mebendazole (100 mg), pyrantel pamoate (11 mg/kg, maximum 1 g), and albendazole (400 mg), all of the above-mentioned drugs are given in a single dose and repeated in two weeks. Mebendazole and albendazole are both adulticidal and ovicidal, whereas pyrantel pamoate is only adulticidal. Given their safety and effectiveness, mebendazole and albendazole are currently the best available drugs for the treatment of pinworm infestation. For pregnant women, pyrantel is preferred to mebendazole and albendazole. Treatment of all household members should be considered, especially if there are multiple or repeated symptomatic infections because reinfection is common even when effective medication is given.</p><p><strong>Conclusion: </strong>In spite of effective treatment of pinworm infestation, recurrences are common. Recurrences are likely due to repeated cycles of reinfecti","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lichen Striatus: An Updated Review. 地衣:最新综述。
IF 2
Current Pediatric Reviews Pub Date : 2024-01-25 DOI: 10.2174/0115733963273945240101042423
Alexander K C Leung, Joseph M Lam, Benjamin Barankin, Kin Fon Leong
{"title":"Lichen Striatus: An Updated Review.","authors":"Alexander K C Leung, Joseph M Lam, Benjamin Barankin, Kin Fon Leong","doi":"10.2174/0115733963273945240101042423","DOIUrl":"https://doi.org/10.2174/0115733963273945240101042423","url":null,"abstract":"<p><strong>Background: </strong>Lichen striatus is a benign dermatosis that affects mainly children. This condition mimics many other dermatoses.</p><p><strong>Objective: </strong>The purpose of this article is to familiarize pediatricians with the clinical manifestations of lichen striatus to avoid misdiagnosis, unnecessary investigations, unnecessary referrals, and mismanagement of lichen striatus.</p><p><strong>Methods: </strong>A search was conducted in June 2023 in PubMed Clinical Queries using the key term \"Lichen striatus\". The search strategy included all observational studies, clinical trials, and reviews published within the past ten years. Only papers published in the English literature were included in this review. The information retrieved from the above search was used in the compilation of this article.</p><p><strong>Results: </strong>Lichen striatus is a benign self-limited T-cell mediated dermatosis characterized by a linear inflammatory papular eruption seen primarily in children. The onset is usually sudden with minimal or absent symptomatology. The eruption in typical lichen striatus consists of discrete, skin- colored, pink, erythematous, or violaceous, flat-topped, slightly elevated, smooth or scaly papules that coalesce to form a dull red, potentially scaly, interrupted or continuous band over days to weeks. Although any part of the body may be involved, the extremities are the sites of predilection. Typically, the rash is solitary, unilateral, and follows Blaschko lines. In dark-skinned individuals, the skin lesions may be hypopigmented at onset. Nails may be affected alone or, more commonly, along with the skin lesions of lichen striatus. The differential diagnoses of lichen striatus are many and the salient features of other conditions are highlighted in the text.</p><p><strong>Conclusion: </strong>Lichen striatus is a self-limited condition that often resolves within one year without residual scarring but may have transient post-inflammatory hypopigmentation or hyperpigmentation. As such, treatment may not be necessary. For patients who desire treatment for cosmesis or for the symptomatic treatment of pruritus, a low- to mid-potency topical corticosteroid or a topical immunomodulator can be used. A fading cream can be used for post-inflammatory hyperpigmentation.</p>","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139566670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Survey on Diagnosis and Prognosis of Prenatal Asphyxia based on Antioxidant Oxidant Balance: Evidence from a Systematic Review and Meta-Analysis. 基于抗氧化剂氧化平衡的产前窒息诊断和预后调查:来自系统回顾和元分析的证据。
IF 2
Current Pediatric Reviews Pub Date : 2024-01-25 DOI: 10.2174/0115733963264881231227112345
Boskabadi Hassan, Amirkhani Samin, Tahereh Loghmani, Zakerihamidi Maryam
{"title":"A Survey on Diagnosis and Prognosis of Prenatal Asphyxia based on Antioxidant Oxidant Balance: Evidence from a Systematic Review and Meta-Analysis.","authors":"Boskabadi Hassan, Amirkhani Samin, Tahereh Loghmani, Zakerihamidi Maryam","doi":"10.2174/0115733963264881231227112345","DOIUrl":"https://doi.org/10.2174/0115733963264881231227112345","url":null,"abstract":"<p><strong>Introduction: </strong>The mechanism of occurrence and complications of asphyxia change in the treatment process and the future prognosis of newborns. One of the discussed mechanisms is the disruption of oxidants to anti-oxidants balance. Therefore, the current study was conducted aiming to systematically review and conduct a meta-analysis on the diagnosis and prognosis of prenatal asphyxia based on oxidant-antioxidant balance.</p><p><strong>Methods: </strong>A comprehensive electronic search was conducted using PubMed, Cochrane Library, Scopus, and Web of Science databases, up to February 2023 to identify relevant studies examining the association between Prooxidant anti-oxidant balance (PAB) and Malondialdehyde 1 levels with the risk of prenatal asphyxia. Only English studies were incorporated. The search terms used included Asphyxia, Diagnosis, Prognosis, Newborns, Prenatal, Oxidant antioxidant balance, and oxidative stress. A total of 13 studies were retrieved. Data regarding the standard mean difference (SMD) were collected, and a pooled SMD with 95%CI was calculated using a random-effect model to determine the strength of the relationship. Furthermore, the risk of publication bias was assessed through funnel plot and Egger's linear regression tests. Inclusion criteria was 1) The studies conducted on neonates, diagnosis and outcomes of prenatal asphyxia, oxidants and antioxidants were included. Research conducted on adults or on animals or review articles, and articles in which only their abstracts were available were excluded. The quality of the reported studies was also assessed.</p><p><strong>Results: </strong>Out of 980 searched articles, 13 articles (10 prospective articles and 3 cross-sectional articles) were studied. An increase in antioxidant enzymes (Glutathione peroxidase (GSH-Px), catalase (CAT) and Plasma superoxide dismutase (SOD)) cannot be dealt with excessive oxidants produced in the body (Plasma and cerebrospinal fluid levels of Malondialdehyde (MDA), free radical products (F8-isoprostane and MDA), saturated fatty acids and % CoQ-10). Prooxidant anti-oxidant balance (PAB) levels among neonates who had asphyxia were announced to be two times higher than normal newborns. PAB values in neonates with asphyxia, who had adverse prognosis, were about three times higher than those with favorable prognosis. The sensitivity of PAB in predicting the prognosis of neonates with asphyxia was reported 83- 89% and its specificity was 71- 92%. The pooled SMD analysis revealed a significant association between PAB and MDA levels with the risk of prenatal asphyxia both overall (SMD = 1.447, 95%CI: 0.961-1.934, P < 0.001), as well as separately in subgroups of PAB (SMD = 1.134, 95%CI: 0.623-1.644, P < 0.001) and MDA (SMD = 1.910, 95%CI: 0.916-2.903, P < 0.001).</p><p><strong>Conclusion: </strong>Our meta-analysis findings revealed the potential of evaluating antioxidant enzymes and oxidant agents, as well as assessing the balance bet","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139566590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Outcomes of Infections in Critically-ill Paediatric Oncology Patients: A Retrospective Observation Study. 重症儿科肿瘤患者感染的发生率和结果:一项回顾性观察研究。
IF 2
Current Pediatric Reviews Pub Date : 2024-01-24 DOI: 10.2174/0115733963264717231208114248
Karen K Y Leung, Pak Leung Ho, Sally C Y Wong, Wilson Y K Chan, Kam Lun Ellis Hon
{"title":"Prevalence and Outcomes of Infections in Critically-ill Paediatric Oncology Patients: A Retrospective Observation Study.","authors":"Karen K Y Leung, Pak Leung Ho, Sally C Y Wong, Wilson Y K Chan, Kam Lun Ellis Hon","doi":"10.2174/0115733963264717231208114248","DOIUrl":"https://doi.org/10.2174/0115733963264717231208114248","url":null,"abstract":"<p><strong>Purpose: </strong>The survival of paediatric oncology patients has improved substantially in the past decades due to advances in the field of oncology. Modern cancer treatments often come with life-threatening complications, of which infection is one of the most common causes in this patient population. This study aims to investigate the prevalence and outcomes of common infections in haemato-oncology patients during their stay in paediatric intensive care unit (PICU) and to identify any factors associated with these infections.</p><p><strong>Methods: </strong>A retrospective observational study was conducted on all children with a haemato-oncology diagnosis or who underwent haematopoietic stem cell transplantation (HSCT) and who were admitted to the Hong Kong Children's Hospital PICU over a one-year period. Infection characteristics and patient outcomes were evaluated and compared between different sub-groups. Univariable and multi-variable analyses were employed to identify risk factors associated with the development of active infection.</p><p><strong>Results: </strong>Forty-five (36.3%) of 124 critically ill haemato-oncology admissions to PICU were associated with infections, of which 31 (25%) admissions involved bacterial infections, 26 (20.9%) involved viral infections and 6 (4.8%) involved fungal infections. Bloodstream infection was the most common type of infection. More than half (61.3%) of the bacterial infections were due to an antibiotic-resistant strain. After adjusting for confounding variables, post-HSCT status and neutropenia were significantly associated with active infections.</p><p><strong>Conclusion: </strong>Infections in critically-ill haemato-oncological patients are associated with post haematopoietic stem cell transplant status and neutropenia. Further study is warranted to review effective strategies that may mitigate the likelihood of infection in this patient population.</p>","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139563103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost and Time Reduction of Industrial Mold Design and Manufacturing by Implementing Additive Manufacturing for Premature Neonatal Prong 通过对早产新生儿棱镜实施增材制造,降低工业模具设计和制造的成本并缩短时间
IF 2
Current Pediatric Reviews Pub Date : 2024-01-24 DOI: 10.2174/0115733963253344231214070824
K. Mirnia, Atousa Kialashaki, Mohammed Heidarzadeh, A. Maghsoudi, Zahra Pourashouri, Abbas Abaei Kashan
{"title":"Cost and Time Reduction of Industrial Mold Design and Manufacturing by Implementing Additive Manufacturing for Premature Neonatal Prong","authors":"K. Mirnia, Atousa Kialashaki, Mohammed Heidarzadeh, A. Maghsoudi, Zahra Pourashouri, Abbas Abaei Kashan","doi":"10.2174/0115733963253344231214070824","DOIUrl":"https://doi.org/10.2174/0115733963253344231214070824","url":null,"abstract":"\u0000\u0000For a long time, molding was one of the most important methods of producing\u0000metal, ceramic, and polymer materials. The two essential factors in this method were always\u0000cost and time. Technology advancements have made it possible to design in 3D using a computer\u0000and additive manufacturing. This article covers methods for using 3D printers to save time\u0000and money in the process of creating the final product. The \"Prong\" molds for premature neonatal\u0000respiratory aid were designed and produced based on neonatologists' considerations.\u0000\u0000\u0000\u0000The study was conducted on fifteen very low birth neonates at Alzahra Hospital in\u0000Tabriz University from September 2017 to September 2019. In the first section, we described dental\u0000plaster material for molding. When using this material, the printing material must be selected\u0000and the parameters, like melting temperature and printer speed, must be controlled to achieve acceptable\u0000quality for the final sample. CAD software can be used to print various objects if the final\u00003D design is appropriate.\u0000\u0000\u0000\u0000We used additive manufacturing technology to create a new design and successfully resolved\u0000bubble issues at a low cost through a combination of creativity and experimentation. The\u0000new mold has cavities that allow the silicon to occupy the entire space and escape any bubbles.\u0000\u0000\u0000\u0000The use of 3D printers allows us to achieve the best design for the prong mold while\u0000reducing both production costs and time. The ultimate mold made of aluminum was finally produced\u0000by the CNC machine. The final product was tested at Al-Zahra Hospital in Tabriz, Iran, and\u0000the results were satisfactory, with no reports of necrosis on the babies' noses.\u0000\u0000\u0000\u0000none\u0000","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139601927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review on Advances in Pediatric Endoscopy in the Management of Inflammatory Bowel Disease 小儿内镜在治疗炎症性肠病方面的进展综述。
IF 2
Current Pediatric Reviews Pub Date : 2024-01-23 DOI: 10.2174/0115733963268547231128101929
Sara Isoldi, Saverio Mallardo, Paolo Quitadamo, Beatrice Leter, Salvatore Cucchiara
{"title":"Review on Advances in Pediatric Endoscopy in the Management of Inflammatory Bowel Disease","authors":"Sara Isoldi, Saverio Mallardo, Paolo Quitadamo, Beatrice Leter, Salvatore Cucchiara","doi":"10.2174/0115733963268547231128101929","DOIUrl":"10.2174/0115733963268547231128101929","url":null,"abstract":"<p><p>Over the past decades, an increased importance has been given to gastrointestinal (GI) endoscopy in the management of children with inflammatory bowel diseases (IBD), considering that mucosal healing has been recognized as the optimal endpoint in the treat-to-target paradigm. The recent advances in technology and anesthesia have facilitated the comprehensive evaluation of the GI tract. In this review, we will discuss the role of ileocolonoscopy, upper GI endoscopy, and device-assisted enteroscopy in the work-up and management of pediatric Crohn’s disease (CD) and ulcerative colitis, with particular attention on non-invasive endoscopic techniques, such as wireless capsule endoscopy. We will also analyze the most commonly used endoscopic scoring systems, including small bowel scoring systems and endoscopic recurrence grading of neo-terminal ileum CD. Moreover, we will focus on the endoscopic management of complications, such as strictures, that commonly require surgery. Lastly, we will discuss cancer surveillance in children with IBD, with particular consideration of the role of high-definition endoscopic equipment and chromoendoscopy in dysplasia detection rates.</p>","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139541184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Submaximal Field Walking Tests Applied in the Cardiopulmonary Assessment in Congenital Heart Diseases: A Systematic Review. 应用于先天性心脏病心肺功能评估的亚最大野外步行测试:系统回顾
IF 2
Current Pediatric Reviews Pub Date : 2024-01-19 DOI: 10.2174/0115733963263592231127042702
Amanda da Silva, Alexia Nadine Puel, Priscilla Moretto, Ana Inês Gonzáles, Anelise Sonza
{"title":"Submaximal Field Walking Tests Applied in the Cardiopulmonary Assessment in Congenital Heart Diseases: A Systematic Review.","authors":"Amanda da Silva, Alexia Nadine Puel, Priscilla Moretto, Ana Inês Gonzáles, Anelise Sonza","doi":"10.2174/0115733963263592231127042702","DOIUrl":"https://doi.org/10.2174/0115733963263592231127042702","url":null,"abstract":"<p><strong>Introduction: </strong>Submaximal field walking tests are easy to apply and low cost, but it is necessary to standardize their application, especially in the pediatric population. The feasibility and its use in patients with congenital heart disease have been studied. To verify which are the submaximal field walking tests applied in the cardiopulmonary assessment of children and adolescents with CHD and to verify if they are being performed as recommended by the standardization protocols/guidelines.</p><p><strong>Methods: </strong>Literature review through a search in six electronic databases, structured in PICO format, without date restrictions. Looking for studies that used submaximal field walking tests in children and adolescents with congenital heart disease aged 5 to 18 years. Methodological quality, effectiveness and safety and risk of bias were assessed.</p><p><strong>Results: </strong>Five studies met the eligibility criteria with a sample of 160 individuals with congenital heart disease, and all used the six-minute walk test. Note that different methodologies and modifications are used. Only the clinical trial showed good methodological quality.Four studies had low risk of bias and one study had moderate risk.</p><p><strong>Conclusion: </strong>Although the six-minute walk test is the only test used as a field test found in our research, there is no standardization in the application of the test, making it difficult to compare the results. In this sense, reducing the limitations and heterogeneity in the application of the test will enable more concrete outcomes and facilitate their reproduction in clinical practice.</p>","PeriodicalId":11175,"journal":{"name":"Current Pediatric Reviews","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139511951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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