S. Etemadi, O. Raiesi, Muhammad Ibrahim Getso, V. Raissi, H. Hoseini
{"title":"A Review of the Prevalence and Diagnostic Points of Cryptosporidium Species in Immunocompromised and Healthy Human Samples in Iran","authors":"S. Etemadi, O. Raiesi, Muhammad Ibrahim Getso, V. Raissi, H. Hoseini","doi":"10.34172/ddj.2021.30","DOIUrl":"https://doi.org/10.34172/ddj.2021.30","url":null,"abstract":"Cryptosporidium species are important intestinal pathogens with widespread distribution in humans and other hosts. Whereas the parasite causes acute and self-limiting gastroenteritis in people with healthy immune systems, many reports on this infection around the world are limited to people with defective or suppressed immune systems who suffer from a persistent and deadly infection. Using laboratory-serological and molecular methods for the detection of Cryptosporidium species in immunocompromised and healthy human samples, recent studies in Iran indicated that the prevalence of Cryptosporidium species in different samples varied between 0 to 14%. The samples in Iranian studies included human fecal and diarrheic samples from diarrheic children, patients with gastroenteritis, immunocompromised individuals, and people in contact with livestock. Furthermore, some species were reported based on molecular studies including Cryptosporidium parvum and Cryptosporidium hominis. Some studies have also reported Cryptosporidium meleagridis. In this review study, data were collected regarding the prevalence of cryptosporidiosis in high-risk individuals such as children and immunocompromised individuals. The results revealed that the higher prevalence of C. parvum in Iranian studies in the last 10 years may be attributed to the transmission of infection from animal sources.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73364702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hossein Farshidi, Mehdi Hassaniazad, Mahmood Hosseinpoor, Abdollah Gharibzadeh, A. Nikpoor, S. Mohseni, Hossein Abbasi, Shideh Rafati, A. Madani, Abdul-Jabbar Zakeri, F. Fakhar, A. Ahmadi, Ali Heyrani, Saeed Kashani, Gholamali Javdan, H. Morshedi, Fatemeh Noroziyan, A. Nejatizadeh
{"title":"Humoral Immune Durability of Anti-SARS-CoV-2 Antibodies in Southern Iran: A Population-Based Survey Study","authors":"Hossein Farshidi, Mehdi Hassaniazad, Mahmood Hosseinpoor, Abdollah Gharibzadeh, A. Nikpoor, S. Mohseni, Hossein Abbasi, Shideh Rafati, A. Madani, Abdul-Jabbar Zakeri, F. Fakhar, A. Ahmadi, Ali Heyrani, Saeed Kashani, Gholamali Javdan, H. Morshedi, Fatemeh Noroziyan, A. Nejatizadeh","doi":"10.34172/ddj.2021.27","DOIUrl":"https://doi.org/10.34172/ddj.2021.27","url":null,"abstract":"Background: To promote mitigation strategies and public health response, this study aimed to evaluate the population-based seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in Hormozgan province. Materials and Methods: The study was conducted within 10 districts of Hormozgan province with 1325 participants for three months by considering three-month successive follow-ups to evaluate the durability of humoral immunity. The participants completed the questionnaire, and blood samples were taken followed by immunoassay SARS-CoV-2 ELISA testing. Results: In general, 717 (54.1%) males and 596 (45.9%) females participated in this study. In phase one, 147 (11.1%) and 182 (14.7%) tested positive for immunoglobulin M (IgM) and IgG, respectively. Upon three months, 13.8% and 17.8% tested positive for IgG and at least for one of the antibodies. Based on the results, 606 (45.7%) cases reported no symptoms while 673 (50.8%) of them reflected at least one. Among 798 (60.2%) participants, the most common symptoms were headache (n = 244, 18.4%), sore throat (n = 186, 14.0%), weakness (n = 150, 11.3%), muscular pain (n = 139, 10.5%), and sputum cough (n = 134, 10.1%). The odds of the antibodies in females was 1.37 (95% CI: 1.03, 1.82, P = 0.03). In phase 2, 43 (5.3%) participants persisted positive for IgG while 559 (73%) tested negative for IgG. Finally, 20% of the suffered participants tested positive for IgG until nine months. Conclusion: Although IgG antibodies decreased in the first six months, their titers persisted stable for nine months. It seems our population has not reached a desirable level of protection. It is stressed that mass vaccination is needed to prevent future epidemic waves.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78449781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of the Mask in Preventing and Controlling the Coronavirus Disease 2019 Pandemic","authors":"A. Tajvar, Ali Mouseli, Hamidreza Ghaffari","doi":"10.34172/ddj.2021.25","DOIUrl":"https://doi.org/10.34172/ddj.2021.25","url":null,"abstract":"Following the outbreak of novel coronavirus disease 2019 (COVID-19), there have been debates among scientific communities, officials, and the public about the role of the mask in controlling and preventing this disease. Nonetheless, there are some ambiguities regarding various aspects of the mask which are still important to be addressed, including the type of the mask to be used, the situation in which the mask should be used, the correct way to use the mask, and the effectiveness of the mask in preventing the disease. Accordingly, addressing these ambiguities could change policy trends and public beliefs about the use of mask and help control the disease. To this end, this study discusses the role of the mask in preventing and controlling the COVID-19 pandemic.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88295593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hossein Farshidi, Moazameh Mohammadi Soleimani, D. Hooshyar
{"title":"Percutaneous Retrieval of a Fragmented Port-a-Cath With the Snaring Technique","authors":"Hossein Farshidi, Moazameh Mohammadi Soleimani, D. Hooshyar","doi":"10.34172/ddj.2021.32","DOIUrl":"https://doi.org/10.34172/ddj.2021.32","url":null,"abstract":"Background: Long-term use of central venous catheters is common in cancer patients for chemotherapy. The remaining of these catheters after the end of the treatment period can be associated with complications such as thrombosis and catheter fragmentation. Case Report: This report presents a 42-year-old woman with a history of colon cancer whose inner part of the vascular access was detached from the outer part after removing the central venous catheter, and the catheter remained inside the internal jugular vein. After preparing the patient’s chest X-ray, the catheter was removed from the femoral vein by percutaneous retrieval and successfully taken out using the snaring technique. Conclusion: Overall, percutaneous retrieval is a safe way to remove intravascular foreign bodies that can prevent major surgical complications.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88461912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marziyeh Ahmadi Mirqhaed, M. Dastoorpoor, A. Behbahani
{"title":"Trend Analysis of Cutaneous Leishmaniasis Incidence in Izeh County During 2014-2019","authors":"Marziyeh Ahmadi Mirqhaed, M. Dastoorpoor, A. Behbahani","doi":"10.34172/ddj.2021.19","DOIUrl":"https://doi.org/10.34172/ddj.2021.19","url":null,"abstract":"Background: A cutaneous form of leishmaniasis (cutaneous leishmaniasis, CL) is becoming increasingly common, and this study was conducted to investigate the epidemiological features of CL in the county of Izeh in Khuzestan province. Materials and Methods: This retrospective cross-sectional research was performed during 2014- 2019. Basic demographic and clinical information was gathered from patients with CL referring to Izeh health centre and then processed using SPSS software, version 25.0. Results: Overall, data related to 131 patients were recorded from 2014 to 2019. The incidence of CL showed a decrease from 16.207 to 5.028 per 100000 individuals in Izeh. Based on the analysis of CL incidence in Izeh county, a statistically significant difference was observed through the mentioned six-year study (P<0.05). Male patients with a frequency rate of 65.6% demonstrated a statistically significant association in the CL and the type of gender compared to 34.4% of females (P<0.05). The age group of 20-29 years old (32.1%) had a higher frequency of CL in the age groups. Finally, there was a statistically considerable discrepancy in the frequencies of infected people with CL related to age groups (P<0.05). Conclusion: Based on the findings and other epidemiological characteristics, Izeh does not seem to be an endemic focus of CL. Nonetheless, it is a concerning situation, and proper preparation is strongly advised for disease control and prevention.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86106380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Samimagham, M. Hassani Azad, M. Arabi, D. Hooshyar, A. Sheikhtaheri, F. Khorrami, S. Hosseini Teshnizi, Mitra Kazemi Jahromi
{"title":"COVID-19 Severity and Comorbidities in Diabetic Patients","authors":"H. Samimagham, M. Hassani Azad, M. Arabi, D. Hooshyar, A. Sheikhtaheri, F. Khorrami, S. Hosseini Teshnizi, Mitra Kazemi Jahromi","doi":"10.34172/ddj.2021.18","DOIUrl":"https://doi.org/10.34172/ddj.2021.18","url":null,"abstract":"Background: This study aimed to investigate the demographic factors, comorbidities, and laboratory results of diabetic patients with coronavirus disease 2019 (COVID-19) severity. Materials and Methods: This cross-sectional study enrolled 171 diabetic patients with COVID-19 admitted based on chest CT scan findings to the COVID-19 ward of Shahid Mohammadi Hospital in Hormozgan, Iran from 1 March to 1 June, 2020. Reverse-transcriptase polymerase chain reaction (RT-PCR) test was performed, and the patients were divided into three groups (mild, moderate, and severe) based on the severity of disease. Then we investigated the demographic factors, comorbidities, and laboratory results of diabetic patients with severe COVID-19 severity. Results: Regarding comorbidities, there was no significant difference between the three groups. Moreover, there was a significantly lower lymphocyte count in the severe group compared to moderate and mild groups (P = 0.001). We showed the increase in blood urea nitrogen (BUN) and creatinine to be significantly associated with increased disease severity (P = 0.001 and P = 0.009, respectively). We also showed a significant difference in aspartate aminotransferase (AST) levels between different groups of patients (P = 0.002) with a higher level of AST in the severe group (P = 0.020). Lactate dehydrogenase (LDH) and troponin were also significantly associated with an increase in COVID-19 severity in patients with diabetes (P = 0.013 and P = 0.002, respectively). Conclusion: There was a significant association between disease severity and BUN, creatinine, AST, LDH, and troponin levels in diabetic patients with COVID-19. There was no significant association between different groups regarding severity of disease and comorbidities.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90024548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anusheh Haghighi, Maryam Dibadin, A. Farahani, M. Abbasi, M. Arabi
{"title":"The Effect of Follow ups with Weekly Phone Calls on the Outcome and Quality of Life Among the Patients with Rheumatoid Arthritis","authors":"Anusheh Haghighi, Maryam Dibadin, A. Farahani, M. Abbasi, M. Arabi","doi":"10.34172/ddj.2021.20","DOIUrl":"https://doi.org/10.34172/ddj.2021.20","url":null,"abstract":"Background: The present study aimed at evaluating the effect of weekly phone calls on treatment outcomes and quality of life among a group of Iranian patients with rheumatoid arthritis (RA). Materials and Methods: In this randomized clinical trial study, 60 patients aged 15-85 with RA were randomly assigned to intervention and control groups. The intervention group, in addition to a monthly assessment on a weekly basis, received a full 3-month follow-up telephone conversation in order to follow the correct and regular use of the drug and respond to the patients’ questions. The control group was only evaluated routinely. Finally, the severity of the disease activity (based on DAS-28) and the quality of life (based on the SF-12 questionnaire) were evaluated after three months. Results: After three months from the onset of intervention, a significant reduction was observed in the number of tender joints, mean erythrocyte sedimentation rate (ESR), and total score of DAS-28 in the intervention group compared to the control group. In addition, after three months of treatment, the quality of life for the intervention group improved significantly more than that of the control group. Conclusion: A weekly phone call with the patients suffering from RA with the purpose to guide the therapeutic process and respond to the patients’ questions could positively improve the severity of the disease along with the quality of life among the patients.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84498095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Aromatherapy with Lavender on Labor Pain: A Literature Review","authors":"Razieh Hatami Rad","doi":"10.34172/ddj.2021.23","DOIUrl":"https://doi.org/10.34172/ddj.2021.23","url":null,"abstract":"Background: Controlling labor pains is now an essential part of midwifery care, and aromatherapy is a well-known medicinal treatment for easing labor pains. The aim of this research was to evaluate and analyze the most recent clinical trial results on the effects of lavender aromatherapy on labor pain management. Methods: Several keywords were searched in the MEDLINE/PubMed, Scopus, and Google Scholar databases, including lavender, Lavandula, childbirth, labor, pregnancy, labor pain, aromatherapy, and delivery. Two authors extracted the data, and the Cochran quality management tool was used to assess the consistency of each study. Results: In general, 7 studies were reviewed after checking the titles and abstracts of the studies and eliminating obsolete or low-quality studies. Two studies were conducted in Egypt and Indonesia, and five studies were conducted in Iran. There were a wide variety of qualities in the studies, which could render more quantitative synthesis impractical. Massage aromatherapy was employed in three trials, and inhalation was applied in four studies. All findings suggested that lavender aromatherapy in both methods could reduce active phase labor pain. Conclusion: Although the results of this study showed that lavender aromatherapy suppressed labor pain, more detailed randomized clinical trials with higher precision are needed to achieve an accurate outcome for data generalization regarding the use of labor pain management.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79366950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atypical Presentation of Aortic Dissection: A Case Report","authors":"Soraya Shamizadeh, Golamreza Faridaalaee","doi":"10.34172/ddj.2021.24","DOIUrl":"https://doi.org/10.34172/ddj.2021.24","url":null,"abstract":"Background: Aortic dissection (AD) is considered to be one of the life-threatening diseases. Quick diagnosis has great significance so that a one-hour delay in treatment leads to a 1-2% increase in mortality. Case Report: The 55-year old obese woman with epigastric pain and right upper quadrant pain referred to the emergency department of our hospital. The acute coronary syndrome was our initial diagnosis but an image similar to a Perl in one cut and a crescent in another cut of computed tomography (CT) drew our attention in the mediastinal view of CT without intravenous contrast that was performed to rule out coronavirus disease-19 (COVID-19). Finally, CT-angiography was requested and AD diagnosis was approved accordingly. Conclusion: The presence of calcification on a non-contrast chest CT in the middle of the aorta or away from the artery wall can be a sign of AD. Thus, special attention should be paid to the atypical symptoms of AD.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79820421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Endurance Training on Plasma Levels of ICAM, VCAM, and OPG in Rats with Experimental Myocardial Infarction: A Gender-Based Study","authors":"M. Ashtari, B. Abedi, H. Fatolahi","doi":"10.34172/ddj.2021.21","DOIUrl":"https://doi.org/10.34172/ddj.2021.21","url":null,"abstract":"Background: The purpose of this study was to investigate the effect of four weeks of endurance training (EXE) on inflammatory markers predicting atherosclerosis by gender. Materials and Methods: Forty male and female Wistar rats were divided into 4 groups including male myocardial infarction (MI), male MI + EXE, female MI, and female MI+EXE. After the induction of MI with two intraperitoneal injections of isoproterenol (150 mg/kg), the training groups performed an (EXE) program for 4 weeks on a treadmill (speed 18 m/min, 30 minutes, 5 sessions per week). The animals were sacrificed 24 hours after the last training session. Finally, data were analyzed using a two-way analysis of variance and Fishers’ least significant difference post hoc test. Results: Despite the clinical difference in the training groups, the intercellular adhesion molecule (ICAM, 3.74±0.61 ng/mL) was more significant in the female MI + EXE group (P=0.009). Conclusion: In general, despite observing clinical changes, there were no significant vascular cell adhesion molecules and osteoprotegerin (OPG) after EXE in cardiovascular inflammatory factors in male and female rats following MI. Nevertheless, gender had a significant independent effect on the ICAM index. The results showed that ICAM values were higher in female rats in comparison with male rats.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86882316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}