Seyed Hesamaddin Banihashemi, A. Karimi, Hasti Nikourazm, Behnaz Bahmanyar, D. Hooshyar
{"title":"Coronavirus Disease 2019 Occupational Considerations for Surgeons: A Review Article","authors":"Seyed Hesamaddin Banihashemi, A. Karimi, Hasti Nikourazm, Behnaz Bahmanyar, D. Hooshyar","doi":"10.34172/DDJ.2021.07","DOIUrl":"https://doi.org/10.34172/DDJ.2021.07","url":null,"abstract":"The severe acute respiratory syndrome coronavirus 2 virus and its associated disease, called coronavirus disease 2019 (COVID-19), first appeared in Wuhan, China in December 2019 and quickly spread around the world. Coronavirus was officially named COVID-19 by the World Health Organization and was recognized as a pandemic due to its rapid spread worldwide. Based on the published data, it is hoped to provide a source for later studies and to help prevent and control the contagious COVID-19 and its characteristics, and considerations that surgeons and medical staff must observe during the epidemic.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87868137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Meidari, M. Ahmadi, Marjan Tari Verdi, S. Zare, M. Mohammadian, M. Rahmati
{"title":"Determining the Relationship Between Fever of Without focus and Latent Pneumonia in Feverish Children in Bandar Abbas, Iran","authors":"Mohammad Meidari, M. Ahmadi, Marjan Tari Verdi, S. Zare, M. Mohammadian, M. Rahmati","doi":"10.34172/DDJ.2021.09","DOIUrl":"https://doi.org/10.34172/DDJ.2021.09","url":null,"abstract":"Background: Fever is one of the most common causes of children’s referral to the emergency department, for which in 20% of cases no clear source is found. Latent pneumonia is not easily differentiable as one of the differential diagnoses of fever of unknown origin (FUO). This study aimed to determine the relationship between FUO and latent pneumonia in feverish children referring to pediatric emergency department. Materials and Methods: The present analytical research was carried out on 220 children with FUO aged 3-36 months referred to pediatric hospital of Bandar Abbas, Iran in 2019. To find the signs and symptoms, demographic information, history, and physical examination results were recorded by a physician using a predetermined checklist. Chest x-ray and blood sample were prepared for white blood cell (WBC) count, C-reactive protein (CRP), and absolute neutrophil count (ANC). Results: The mean age of the patients was 18.38±8.6 months. There was no significant difference between the mean fever, pulse rate, respiratory rate, WBC count, erythrocyte sedimentation rate (ESR), and ANC among the three groups differentiated by their diagnosis. The mean CRP in the bacterial pneumonia group was 68.17±24.13, while it was 35.00±20.43 in the viral infection group and 35.71±26.20 in the group of other diseases; the difference was statistically significant (P=0.004). Conclusion: Although there was no significant difference between WBC, ANC, and ESR and latent pneumonia, there was a significant difference between CRP and latent pneumonia, whose value was larger in these patients.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88450836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Malekzadeh, Shaghayegh Kermaninezhad, A. Nikpoor, Mohammad Ali Vahidipour, Ali Salimi Asl
{"title":"Generated Immune Responses and Antibody-Mediated Immunity Against Corona Virus Disease-19: An Updated Review","authors":"F. Malekzadeh, Shaghayegh Kermaninezhad, A. Nikpoor, Mohammad Ali Vahidipour, Ali Salimi Asl","doi":"10.34172/DDJ.2020.07","DOIUrl":"https://doi.org/10.34172/DDJ.2020.07","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is a new pathogen which has become an uncontrollable pandemic. On the other hand, the humoral immune system, as a defensive line, protects the body by producing antibodies. Immunoglobulin M (IgM) and G (IgG) are considered as the most important antibodies that are produced by the immune system of the host. Previous evaluations on the production of IgM and IgG antibodies by patients suffering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection specifies that IgM is an acute phase antibody and increases on the first days of infection. Then, as the chronic phase begins, the level of the IgM decreases and switches to the production of IgG. In addition, the durability of the IgG antibody shows the duration of the immunity against COVID-19. Thus, the present review article focused on the antibody production mechanism in studies conducted on COVID-19 patients, the protection role of antibodies, and their stability.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83987582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehdi Behjati Ardakani, T. Aghamolaei, Mehdi Hasani Azad, Moussa Soleimani Ahmadi, F. Zare, M. Khademian, Mohammad Reza Zare, Hadi Eshaghi Sani, A. Madani, M. Zare
{"title":"Evaluation of Health Anxiety in Healthcare Workers During Coronavirus Disease 2019 (COVID-19) Pandemic","authors":"Mehdi Behjati Ardakani, T. Aghamolaei, Mehdi Hasani Azad, Moussa Soleimani Ahmadi, F. Zare, M. Khademian, Mohammad Reza Zare, Hadi Eshaghi Sani, A. Madani, M. Zare","doi":"10.34172/DDJ.2021.11","DOIUrl":"https://doi.org/10.34172/DDJ.2021.11","url":null,"abstract":"Background: Considering the importance of health anxiety (HA) and its impact on the management of a pandemic, the present study investigated HA among healthcare workers during coronavirus disease 2019 (COVID-19) pandemic. Materials and Methods: The sample of this cross-sectional study consisted of 220 healthcare staff working in health centers and hospitals in Iran. Participants were selected using convenience sampling method. The data collection tool was a two-part questionnaire. The first part contained demographic information and the second part included a health anxiety questionnaire (HAQ). This questionnaire was provided to the target community through social media and the required data was collected. Data analysis was carried out using IBM SPSS Statistics for Windows, version 21 (IBM Corp., Armonk, N.Y., USA). Results: In the present study, out of 220 participants 128 (58.2%) were employed in health centers and 92 (41.8%) in hospitals. The mean HA score was 17.36 ± 7.66. Moreover, the mean HA scores in health center and hospital personnel was 17.81± 8.02 and 16.52 ± 6.78, respectively, which were not significantly different (P=0.217). The results showed that exercise and chronic disease are significant predictors of HA (P=0.0001 and P=0.043, respectively). Conclusion: The HA level was very high in healthcare personnel during the COVID-19 pandemic. This study showed that physical activity and having an underlying disease are important predictors of HA. Hence, in order to reduce the level of anxiety in healthcare personnel, it is recommended to plan regular physical activity programs and make changes in the work schedule of personnel with underlying disease.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73142989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Habib Shareinia, L. Sadeghmoghadam, M. Mokhtarzadeh, Seyede Maryam Zahrayi, N. Jafari, Reza Noori
{"title":"Relationship Between Polypharmacy and Medication Adherence in the Hypertensive Elderly Patients","authors":"Habib Shareinia, L. Sadeghmoghadam, M. Mokhtarzadeh, Seyede Maryam Zahrayi, N. Jafari, Reza Noori","doi":"10.34172/DDJ.2020.05","DOIUrl":"https://doi.org/10.34172/DDJ.2020.05","url":null,"abstract":"Background: Proper adherence to the medication regimen in hypertensive elderly patients is important. This study aimed to investigate the relationship between polypharmacy with adherence to the medication regimen in hypertensive elderly patients. Materials and Methods: Using stratified random sampling method, the present descriptive-analytical study was performed on 384 hypertensive elderly patients in Gonabad, Iran in 2016. The study population included males and females aged over 60 years who were covered by Gonabad urban and rural community health centers. Data were collected using demographic questionnaire and the eight-item Morisky Medication Adherence Scale (MMAS-8). Results: The mean daily medications in participants was 6±2.43, and a high medication adherence was observed among 36.7% of the subjects. Chi-square test showed a significant relationship between polypharmacy and medication adherence (P = 0.006). Conclusion: Physicians and nurses can play an important role in preventing the risks of polypharmacy, as well as non-adherence to medication regimen by educating the hypertensive elderly patients or their caregivers.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81060875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sajjad Shamloo, A. Alavi, K. Nematpour, Z. Mirshekari, A. Taheri
{"title":"Menstrual Patterns and Disorders Among Adolescent Girls in Bandar Abbas, Iran","authors":"Sajjad Shamloo, A. Alavi, K. Nematpour, Z. Mirshekari, A. Taheri","doi":"10.34172/DDJ.2020.04","DOIUrl":"https://doi.org/10.34172/DDJ.2020.04","url":null,"abstract":"Background: Menstrual cycle is one of the important factors to protect women’s sexual health, and it is affected by various factors in different individuals. Disrupting the balance of this cycle imposes numerous impacts on women’s health. The present study aimed to investigate the incidence rate and factors associated with menstrual disorders among high school girls in Bandar Abbas, Iran. Materials and Methods: The population of current cross-sectional study was selected through a multi-stage cluster sampling method. Data were collected through a questionnaire. We entered the data of 370 individuals into SPSS software (version 23, SPSS Inc., Chicago, IL, USA) and analyzed them using descriptive statistics and Mann-Whitney U test. The significant level was considered as 0.05. Results: The mean age of the subjects was 16.29 ± 0.89 years. In addition, the mean menarche age and BMI were 12.82 ± 1.09 years and 20.67 ± 4.17. The incidence rates of hypomenorrhea, hypermenorrhea, amenorrhea, oligomenorrhea, and polymenorrhea were 24.6%, 8.4%, 9.7%, 5.7%, and 13.0%, respectively. There was a significant relationship between age trend with disorders like amenorrhea, oligomenorrhea, and polymenorrhea. However, there was no significant relationship between age trend with hypomenorrhea and hypermenorrhea. Generally, the prevalence of menstrual disorders increased with the increase in BMI, though this relationship was not significant. Conclusion: Due to the relatively high incidence of menstrual disorders in the present study and since numerous major illnesses such as infertility originate from these disorders, we suggest that effective measures be taken to promote the culture of menstrual health among adolescent girls and correct the misconceptions of families.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74658493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Samimagham, Shirin Mehraban, M. Nikparvar, M. Arabi, E. Boushehri, Mitra Kazemi Jahromi
{"title":"The Association of Thyroid Hormones With β-HCG in Patients With Hydatidiform Mole","authors":"H. Samimagham, Shirin Mehraban, M. Nikparvar, M. Arabi, E. Boushehri, Mitra Kazemi Jahromi","doi":"10.34172/DDJ.2020.02","DOIUrl":"https://doi.org/10.34172/DDJ.2020.02","url":null,"abstract":"Background: A hydatidiform mole or molar pregnancy is the most prevalent gestational trophoblastic disease (GTD). About 55%-60% of women with trophoblastic diseases have overt hyperthyroidism at the time of diagnosis, which may have severe manifestations. This study examined the relationship between gestational hypertension and the level of thyroid hormones with beta human chorionic gonadotropin (β-HCG) in patients with a hydatidiform mole. Materials and Methods: This cross-sectional study enrolled 65 patients with a hydatidiform mole admitted to Khalij-e Fars hospital, Bandar Abbas, Iran. Patients were divided into three groups of clinical hyperthyroidism, subclinical hyperthyroidism, and healthy. The serum levels of thyroid-stimulating hormone (TSH), T4, T3, and β-HCG were checked in all subjects, and the relationship between gestational hypertension and the level of thyroid hormones with β-HCG in patients with a hydatidiform mole was examined. Results: The mean age of patients was 29.93 ± 9.04 years, and their mean gestational age was 11.09 ± 4.2 weeks. In this study, 12.3% of the patients had subclinical hyperthyroidism, 41.5% had clinical hyperthyroidism, and 46.2% were healthy. A significant relationship was found between the serum level of β-HCG and thyroid function in patients with clinical and subclinical hyperthyroidism compared to the healthy group (P= 0.001). No significant relationship was found between systolic/ diastolic blood pressure and the serum level of β-HCG. Conclusion: A significant relationship was observed between the serum levels of β-HCG and TSH, free T3, and free T4 in patients with a hydatidiform mole and thyrotoxicosis. Thus, early diagnosis of hyperthyroidism can help treat these patients more quickly.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77190575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Hajinezhad, Shaghayegh Hajian Shahri, A. Rahdar, Hojjat Zamanian
{"title":"Effects of Cerium Oxide Nanoparticles on Biochemical Parameters and Histopathological Changes in Lead-Intoxicated Rats","authors":"M. Hajinezhad, Shaghayegh Hajian Shahri, A. Rahdar, Hojjat Zamanian","doi":"10.34172/DDJ.2020.01","DOIUrl":"https://doi.org/10.34172/DDJ.2020.01","url":null,"abstract":"Background: The present study was conducted to investigate the potential protective effect of cerium oxide nanoparticles (CeNPs) against lead acetate-induced toxicity. Materials and Methods: In this study, 30 adult male Wistar rats were randomly divided into three groups and treated simultaneously, except for the normal control, for 5 weeks with lead acetate in drinking water (1000 mg/L). Control rats and negative control rats received saline intraperitoneally. At the same time, the third group was treated with intraperitoneal injections of CeNPs at the dose of 0.5 mg/kg 1 week before lead administration, and continued with its administration. Finally, serum was obtained by the conventional methods and rats were sacrificed to obtain liver, heart, testis, and kidney tissue for histopathological examinations. Results: The lead-treated group showed significant increases in blood urea nitrogen (BUN), serum creatinine, serum aspartate aminotransferase (AST), serum alanine aminotransferase (ALT), and malondialdehyde (MDA) levels (P<0.01). Lead-intoxicated rats treated with CeNPs showed a significant decrease in serum lactate dehydrogenase (LDH), AST, and ALT levels compared to the untreated negative control group (P<0.01). The histopathological examination of liver and kidney tissues showed signs of lead-induced injuries, necrotic hepatocytes, and glomerulosclerosis. The CeNPs-treated group showed noticeable reductions in histopathological signs of lead-induced injuries. Lipid peroxidation levels were also lower in CeNPs-treated rats than negative controls (P<0.05). Conclusion: The current experimental study proved the protective effects of CeNPs in rats exposed to chronic lead-induced toxicity; however, more experiments are required to evaluate the possible side effects and interactions.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77587972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of X-Ray Tube Technical Factors: Tube Voltage and Exposure Time in Erbil Medical Imaging Centers","authors":"F. F. Hassan","doi":"10.34172/DDJ.2020.03","DOIUrl":"https://doi.org/10.34172/DDJ.2020.03","url":null,"abstract":"Background: An evaluation of certain radiographic factors affecting patient exposure during medical imaging was carried out. Factors considered included selection of tube kilovoltage and time exposure combination. An increase in X-ray tube voltage increases the amount of radiation coming out of the X-ray tube, as well as the amount of skin dose in the image. This study aimed to assess the possibility of reducing the voltage and exposure time in medical imaging centers. The study indeed intended to protect patients from the risk of developing cancer with excessive radiation dose. Materials and Methods: This study was performed in Erbil hospitals, Iraq. NOMEX multimeter (Finland, PTW) was used to measure radiation dose (mGy), total voltage, current (mA), exposure time (s), and total filtration in 150 patients undergoing different X-ray examinations. Results: The results showed that the highest output was obtained in the age group of 42-70 years (dose range: 52.43–19.46 mGy), followed by the age group of 50-70 years (dose range: 39.9–25.63 mGy) and the age group of 10–40 years (dose range: 30.35–10.55 mGy). Conclusion: The high voltage (kVp) and high exposure time to be important factors to increase patient doses via increasing the exposure dose. Thus, optimization of exposure time and voltage is recommended for all cancer patients undergoing medical imaging with high voltage and long exposure time.","PeriodicalId":11143,"journal":{"name":"Disease and Diagnosis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82259004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}