Danish medical journal最新文献_第6页

Adding glue to the surgical site after surgery for lower-extremity fractures. 下肢骨折手术后在手术部位添加胶水。

IF 1.1 4区医学

Danish medical journal Pub Date : 2026-04-17 DOI: 10.61409/A11250949

Sükriye Corap Gellert, Abdullahi Abdirisak Hirsi, Michael Brix, Bjarke Viberg

{"title":"Adding glue to the surgical site after surgery for lower-extremity fractures.","authors":"Sükriye Corap Gellert, Abdullahi Abdirisak Hirsi, Michael Brix, Bjarke Viberg","doi":"10.61409/A11250949","DOIUrl":"10.61409/A11250949","url":null,"abstract":"Introduction: Surgical site infection is a concern after lower-extremity fracture surgery, and post-operative wound oozing may increase this risk. Applying glue to the incision could reduce oozing and thereby reduce the need for adhesive patch (AP) changes. This study compared AP change rates in adults with surgically treated lower-extremity fractures with and without the addition of wound glue.Methods: In this prospective cohort study, lower-extremity fractures treated surgically with implants were included, while external fixation and in-hospital deaths were excluded. Patients were enrolled over four months: two as controls and two with glue added to the wound. The primary outcome was AP change on all surgical wounds; secondary outcomes were AP change by fracture location, wound closure method and incision length (small: screw/nail; large: arthroplasty/plate). Follow-up continued throughout admission.Results: Among 339 patients, 162 received no glue and 177 received glue. The median age was 76 years, 55% were female and femoral fractures predominated. Groups were comparable at baseline. AP change occurred in 44% without glue and 35% with glue (p = 0.097). For large incisions, AP change was 42% without glue versus 27% with glue (p = 0.040). No differences were found by fracture location, surgery type or closure method.Conclusions: Adding glue showed no significant overall reduction in AP changes. However, in large incisions, glue reduced AP changes by 15 percentage points, suggesting a benefit in this subgroup.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Very early medical abortion before confirmed intrauterine pregnancy. 确认宫内妊娠前的早期药物流产。

IF 1.1 4区医学

Danish medical journal Pub Date : 2026-04-17 DOI: 10.61409/A11250983

Ervin Kallfa, Sven Hoedt Karstensen, Brita Frederiksen Møller, Finn Friis Lauszus, Pernille Ravn

{"title":"Very early medical abortion before confirmed intrauterine pregnancy.","authors":"Ervin Kallfa, Sven Hoedt Karstensen, Brita Frederiksen Møller, Finn Friis Lauszus, Pernille Ravn","doi":"10.61409/A11250983","DOIUrl":"10.61409/A11250983","url":null,"abstract":"Introduction: Medical abortion using mifepristone and misoprostol is effective and safe, but evidence is limited in very early gestation before ultrasound confirmation of an intrauterine pregnancy (IUP).Methods: This single-centre prospective cohort study included 100 women between 2023 and 2025 who requested medical abortion up to 6+0 weeks of gestation and had a non-confirmed IUP on ultrasound (empty cavity or sac-like structure without embryonic pole). Participants initiated immediate medical abortion according to the WHO-recommended protocol. The primary outcome was complete abortion without the need for surgical intervention.Results: Complete abortion was achieved in 95% of the participants without the need for surgical intervention. The ectopic pregnancy rate was 2%, all of which were diagnosed before rupture. 2% required additional medical treatment, and 2% surgical intervention. No serious adverse events occurred.Conclusions: Medical abortion before visible IUP is as effective as standard treatment. Very early medical abortion can be implemented safely and effectively with structured follow-up, allowing for earlier treatment without compromising safety.Funding: None.Trial registration: The study was approved by the University Hospital of Southern Denmark, Sygehus Sønderjylland, record no.:24/44840.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Limited interventions to improve male fertility. 提高男性生育能力的干预措施有限。

IF 1.1 4区医学

Danish medical journal Pub Date : 2026-04-07 DOI: 10.61409/A11250947

Martin Blomberg Jensen

{"title":"Limited interventions to improve male fertility.","authors":"Martin Blomberg Jensen","doi":"10.61409/A11250947","DOIUrl":"10.61409/A11250947","url":null,"abstract":"Identifying treatments for male infertility has received limited focus, partly because of the success of assisted reproductive techniques (ART), where only few spermatozoa are needed to fertilise the oocyte in vitro. The successful development of ART has created a paradox because we now initiate treatment of the woman even when male-factor infertility is the cause of the couple's inability to conceive. Increased awareness of lower fertility rates, focus on reproductive problems, and the MeToo movement have stimulated interest in male infertility, although neither researchers, governments, nor the pharmaceutical industry are investing sufficient resources to revolutionise infertility treatment by developing innovative therapies for male infertility. This review summarises the challenges we face in developing novel treatment options for male infertility, highlights prior efforts and presents several considerations for future studies. Hopefully, in the near future, we will be able to offer treatment options for subsets of infertile men rather than solely relying on their healthy partners undergoing hormone treatment and subsequent ART, but this requires that authorities, funding bodies, researchers, the pharmaceutical industry and the infertile men themselves prioritise efforts to achieve this.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 5","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Danish perspective on the use of wearables for digital monitoring. 丹麦人对使用可穿戴设备进行数字监控的看法。

IF 1.1 4区医学

Danish medical journal Pub Date : 2026-03-19 DOI: 10.61409/A06250536

Mads Ørbæk Andersen, Joakim Bo Kunkel, Helena Dominquez, Morten Kjøbek Lamberts, Edina Hadziselimovic, Anne Blaabjerg Myhlendorph, Philip Samuel Osbak, Peter Laursen Graversen

{"title":"A Danish perspective on the use of wearables for digital monitoring.","authors":"Mads Ørbæk Andersen, Joakim Bo Kunkel, Helena Dominquez, Morten Kjøbek Lamberts, Edina Hadziselimovic, Anne Blaabjerg Myhlendorph, Philip Samuel Osbak, Peter Laursen Graversen","doi":"10.61409/A06250536","DOIUrl":"10.61409/A06250536","url":null,"abstract":"Introduction: Tension band wiring (TBW) is one of the most commonly used methods of fixation for displaced olecranon fractures. This study aimed to assess whether implant positioning (IMPO) of TBW for olecranon fractures was associated with complications.Methods: This was a multicentre cohort study. Eligible patients were retrieved from the hospitals' administrative databases using diagnosis codes for elbow and olecranon fractures. The patients' healthcare files were reviewed for demographics and complications. A major complication was defined as any reoperation within eight weeks or deep infection. Any loss of fixation was added to define surgical complications. Preoperative X-rays were classified according to the Mayo classification. Post-operative X-rays were evaluated, and the IMPO of TBW was rated on a 0-10 scale, yielding 10 points if all conditions were met. A high IMPO score was 9-10 points, a low score was eight points or less.Results: A total of 307 patients were included: 76% with Mayo type 2A and 20% with type 2B. The TBWs were rated with a median score of eight points (range: 3-10), and 11.8% had major complications. There was a 5% complication rate with a high IMPO score, compared with 15% with a low score (p = 0.010). A total of 105 patients (34%) had surgical complications: 21% with a high IMPO score and 44% with a low IMPO score.Conclusions: The IMPO score after TBW for olecranon fractures has a clear correlation with post-operative complications. We propose that at least nine out of ten points should be achieved before surgery is acceptable.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 4","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of hospital rotation on general practitioner trainee learning. 医院轮转对全科医生实习生学习的影响。

IF 1.1 4区医学

Danish medical journal Pub Date : 2026-03-19 DOI: 10.61409/A05250443

Katerina Bray, Ragnhild Holgaard, Birgitte Bruun

{"title":"Effects of hospital rotation on general practitioner trainee learning.","authors":"Katerina Bray, Ragnhild Holgaard, Birgitte Bruun","doi":"10.61409/A05250443","DOIUrl":"10.61409/A05250443","url":null,"abstract":"Introduction: Denmark is experiencing a shortage of general practitioners (GPs), with rural regions like Region Zealand being particularly affected. Despite efforts to attract GP trainees to these positions, many remain vacant, raising concerns about future access to primary care. A possible barrier to recruitment in underserved regions is the hospital-based portion of GP training, which may shape trainees' perceptions of rural practice. Understanding how hospital rotations shape learning, supervision and well-being is essential for informing strategies to improve recruitment and retention.Methods: A cross-sectional survey was conducted among all 55 GP trainees in hospital rotations in Region Zealand. An anonymised questionnaire assessed supervision, learning opportunities and work environment. Quantitative data were analysed statistically, and qualitative responses underwent thematic analysis.Results: Among 55 trainees, 33 (60%) responded. Most respondents valued supervision and relevant learning experiences, though the quality and consistency of these experiences varied. Only 21% reported GP-specific educational activities. High-value learning formats included outpatient clinics and peer sparring.Conclusions: Hospital rotations are vital to GP training but face structural and educational challenges. Enhancing supervision, relevance of learning, and support may improve training and retention in rural areas.Funding: This work was supported by the \"En læge tæt på dig\" grant.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 4","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development, face validity and acceptability of the Danish version of the Groin Hernia-Q. 丹麦版腹股沟疝- q的发展、面部有效性和可接受性。

IF 1.1 4区医学

Danish medical journal Pub Date : 2026-03-19 DOI: 10.61409/A10250804

Anders Gram-Hanssen, Jason Joe Baker, Hugin Reistrup, Jacob Rosenberg

{"title":"Development, face validity and acceptability of the Danish version of the Groin Hernia-Q.","authors":"Anders Gram-Hanssen, Jason Joe Baker, Hugin Reistrup, Jacob Rosenberg","doi":"10.61409/A10250804","DOIUrl":"10.61409/A10250804","url":null,"abstract":"Introduction: The objective of this study was to describe the development of the Danish version of the Groin Hernia-Q, a new patient-reported outcome measure for patients undergoing groin hernia repair, and to assess its face validity and acceptability.Methods: The Groin Hernia-Q was adapted from the Abdominal Hernia-Q through an iterative process involving an expert committee and refinement interviews with patients with groin hernia. Interviews focused on the relevance, comprehensiveness and comprehensibility of questionnaire items. Following refinement, the Groin Hernia-Q was evaluated using the QQ-10 instrument in a cross-sectional patient survey. Descriptive statistics were used to summarise participant characteristics and QQ-10 scores.Results: A total of 20 patients participated in refinement interviews, leading to the addition of new items, removal of items, clarifications of wording, improved lay understanding and structural adjustments. A total of 108 patients submitted complete survey responses. The mean QQ-10 \"Value\" sum score was 75.7% for the preoperative form and 80.7% for the post-operative form, both exceeding the predefined target of > 60%. \"Burden\" sum scores were 15.9% and 15.1%, respectively, below the maximum acceptable threshold of 40%. These results suggest that the Groin Hernia-Q has good face validity and acceptability.Conclusion: The Danish version of the Groin Hernia-Q demonstrated high face validity and acceptability among patients with groin hernia.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 4","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outpatient versus inpatient initiation of home mechanical ventilation in patients with amyotrophic lateral sclerosis - a protocol for a randomised trial. 肌萎缩性侧索硬化症患者门诊与住院患者开始家庭机械通气-一项随机试验方案。

IF 1.1 4区医学

Danish medical journal Pub Date : 2026-03-19 DOI: 10.61409/A09250733

Janne Bøgh Stokholm, Simone Henrietta Lisa Küchen, Kirsten Møller, Mona Ring Gätke, Kirsten Svenstrup, Anne Kathrine Staehr-Rye

{"title":"Outpatient versus inpatient initiation of home mechanical ventilation in patients with amyotrophic lateral sclerosis - a protocol for a randomised trial.","authors":"Janne Bøgh Stokholm, Simone Henrietta Lisa Küchen, Kirsten Møller, Mona Ring Gätke, Kirsten Svenstrup, Anne Kathrine Staehr-Rye","doi":"10.61409/A09250733","DOIUrl":"10.61409/A09250733","url":null,"abstract":"Introduction: In-home non-invasive ventilation (NIV) is associated with prolonged life and improved quality of life in patients with hypoventilation due to amyotrophic lateral sclerosis (ALS). The initiation of NIV is scheduled for a 1-2-night hospital stay. Telemedicine enables remote monitoring and adjustment of respiratory treatment. These possibilities should be examined to improve patients' experiences and adherence to treatment while freeing up resources in the healthcare system. We hypothesise that outpatient initiation of NIV combined with close telemonitoring in patients with ALS is non-inferior to standard initiation of NIV in adherence to treatment.Methods: This is a randomised, controlled, non-inferiority study. A total of 46 patients with ALS scheduled for initiation of NIV are randomised to start NIV either as an outpatient combined with close telemonitoring or during hospitalisation for 1-2 nights. The primary outcome is NIV adherence after three months, measured as minutes per day for the past seven days. Secondary outcomes are patient satisfaction with NIV treatment and its initiation after three months, assessed on a 1-5 rating scale.Conclusions: The study is the first randomised, controlled study assessing the combination of outpatient initiation of NIV and close telemedical follow-up in patients with a progressive neuromuscular disease. The results may be applicable to other patient populations initiating NIV, e.g., patients with obesity hypoventilation syndrome.Funding: The study was supported by grants from ALS-fonden and Muskelsvindfonden.Trial registration: NCT05829330.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 4","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tokyo Guidelines' performance in predicting acute cholangitis among emergency department patients. 东京指南在预测急诊科患者急性胆管炎中的表现。

IF 1.1 4区医学

Danish medical journal Pub Date : 2026-03-19 DOI: 10.61409/A09250722

Amalie Kuno Riis, Christina Søndergaard Willumsen, Annmarie Touborg Lassen, Flemming Schønning Rosenvinge, Isik Somunco Johansen, Christian Backer Mogensen, Stig Borbjerg Laursen

{"title":"Tokyo Guidelines' performance in predicting acute cholangitis among emergency department patients.","authors":"Amalie Kuno Riis, Christina Søndergaard Willumsen, Annmarie Touborg Lassen, Flemming Schønning Rosenvinge, Isik Somunco Johansen, Christian Backer Mogensen, Stig Borbjerg Laursen","doi":"10.61409/A09250722","DOIUrl":"10.61409/A09250722","url":null,"abstract":"Introduction: Acute cholangitis (AC) is associated with a high mortality even among treated patients. Therefore, early diagnosis and treatment are important for improving prognosis. We investigated the discriminatory ability of the Tokyo Guidelines 2018 (TG18) regarding the presence of inflammation (A criterion) and affected liver parameters (B criterion) as a guide to diagnose AC among unselected patients in the emergency department (ED).Methods: The study was designed as a cohort study of adult ED patient visits in the Region of Southern Denmark. The cohort included patient visits collected from seven EDs between 1 January 2016 and 20 March 2018. We examined the diagnostic accuracy of the TG18 A and B criteria. This project was approved by the Danish Patient Safety Authority (identifier 3-3013-2272/1). The Region of Southern Denmark authorised data storage (identifier 17/24904, amendment identifier 20/24502).Results: We included 202,881 ED patient visits, of which 19,816 met the TG18 A and B criteria. A total of 517 patient visits had a discharge diagnosis compatible with AC. The TG18 had a sensitivity of 85.1% (95% CI: 81.7-88.1%) and a specificity of 90.4% (95% CI: 90.3-90.6%).Conclusions: The TG18 A and B criteria demonstrated high diagnostic accuracy for predicting AC, even among unselected adult patients in the ED, and were effective at identifying patients who required radiological imaging to confirm or rule out suspected AC.Funding: None.Trial registration: Not relevant.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 4","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shared decision-making in medical education - a systematic review. 医学教育中的共同决策——系统回顾。

IF 1.1 4区医学

Danish medical journal Pub Date : 2026-03-19 DOI: 10.61409/A04250257

Anna Sofie Kiel Ørom, Peter Musaeus

{"title":"Shared decision-making in medical education - a systematic review.","authors":"Anna Sofie Kiel Ørom, Peter Musaeus","doi":"10.61409/A04250257","DOIUrl":"10.61409/A04250257","url":null,"abstract":"Introduction: This systematic review examined teaching strategies used to enhance medical students' skills in shared decision-making (SDM) and their impact on students' learning and educational outcomes.Methods: Twenty-three studies published between 2014 and 2025 were identified through systematic searches of PubMed, Scopus and Embase. Eligible studies evaluated SDM-focused educational interventions for medical students and reported SDM-related outcomes.Results: Teaching approaches varied widely, most often involving role-play with SPs or peers, case-based discussions and blended or online modules. Despite heterogeneous outcome measures, experiential methods consistently enhanced students' confidence, communication and attitudes towards SDM. Most studies relied on self-reported data rather than validated, performance-based tools, and few studies included follow-up.Conclusions: Although heterogeneity limits firm conclusions, active, experiential approaches appear most promising in developing SDM competencies among medical students. This review synthesises current approaches to SDM training and highlights key research gaps, including the need for validated, performance-based, longitudinal studies to determine which teaching strategies most effectively support long-term competence in SDM.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 4","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A study protocol for a randomised trial of bracing after ankle fracture. 踝关节骨折后支架的随机试验研究方案。

IF 1.1 4区医学

Danish medical journal Pub Date : 2026-03-19 DOI: 10.61409/A09250748

Jonas Ammundsen Ipsen, Anders Holsgaard-Larsen, Charlotte Abrahamsen, Per Hviid Gundtoft, Matthew Costa, Stinus Storm Mikkelsen, Asbjørn Hróbjartsson, Bjarke Viberg

{"title":"A study protocol for a randomised trial of bracing after ankle fracture.","authors":"Jonas Ammundsen Ipsen, Anders Holsgaard-Larsen, Charlotte Abrahamsen, Per Hviid Gundtoft, Matthew Costa, Stinus Storm Mikkelsen, Asbjørn Hróbjartsson, Bjarke Viberg","doi":"10.61409/A09250748","DOIUrl":"10.61409/A09250748","url":null,"abstract":"Introduction: Ankle fractures are common and debilitating injuries usually treated with immobilisation using a foot-ankle brace (walker). Emerging evidence suggests that a less restrictive ankle stirrup may accelerate recovery without increasing complications, and patients tend to prefer ankle stirrups. However, evidence supporting their non-inferiority is inconclusive. The aim of this study is to assess whether ankle stirrups are non-inferior to walkers in improving function and pain measured by the Manchester-Oxford Foot Questionnaire three months after ankle fracture.Methods: The trial will be a two-phase, multicentre, pragmatic, non-inferiority randomised controlled trial. Patients ≥ 18 years with surgically or non-surgically treated ankle fractures will be included. A three-month pilot phase will assess trial feasibility, including recruitment rates. The full trial will randomise a maximum of 1,400 patients. The sample size is estimated to be sufficient to assess non-inferiority in the overall population and to explore non-inferiority in six subgroups stratified by sex and age (males 18-39 years, males 40-59 years and 60+ years) and treatment (surgical or non-surgical).Conclusions: The bracing after ankle fracture trial will determine whether ankle stirrups are non-inferior to walkers in terms of patient-reported function and pain. Secondarily, the study will assess whether the ankle stirrup facilitates faster recovery of function, earlier return to work, and reduced healthcare costs. Findings will support evidence-based decision-making with respect to patient preferences.Funding: Independent Research Fund Denmark, Grant no. 10.46540/4308-00191B.Trial registration: Clinicaltrials: NCT07163091.","PeriodicalId":11119,"journal":{"name":"Danish medical journal","volume":"73 4","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0