Current Opinion in Electrochemistry最新文献

Double-Layer Capacitance on Pt(111): Notes and Hypotheses on Experimental Challenges Pt（111）上的双层电容：实验挑战的注解和假设

IF 6.9 2区化学

Current Opinion in Electrochemistry Pub Date : 2026-05-09 DOI: 10.1016/j.coelec.2026.101866

Jun Huang

引用次数: 0

Electrochemical impedance spectroscopy for characterizing neural electrodes 表征神经电极的电化学阻抗谱

IF 6.9 2区化学

Current Opinion in Electrochemistry Pub Date : 2026-04-01 Epub Date: 2026-01-03 DOI: 10.1016/j.coelec.2025.101807

Cynthia C. Eluagu , Bernard W. Biney , Stuart F. Cogan , Kevin J. Otto , Mark E. Orazem

引用次数: 0

CRISPR-integrated electrochemical biosensors for precision molecular diagnostics 用于精确分子诊断的crispr集成电化学生物传感器

IF 6.9 2区化学

Current Opinion in Electrochemistry Pub Date : 2026-04-01 Epub Date: 2026-01-14 DOI: 10.1016/j.coelec.2026.101813

Lorelai Schoch , Ryan Preska , Deependra K. Ban , Kiana Aran

{"title":"CRISPR-integrated electrochemical biosensors for precision molecular diagnostics","authors":"Lorelai Schoch , Ryan Preska , Deependra K. Ban , Kiana Aran","doi":"10.1016/j.coelec.2026.101813","DOIUrl":"10.1016/j.coelec.2026.101813","url":null,"abstract":"<div><div>Electrochemical biosensors have significantly advanced diagnostics, particularly point-of-care glucose monitoring, due to their speed, affordability, and portability. Despite these successes, expanding their application to detect DNA, RNA, and microRNA remains challenging, primarily due to limited sensitivity and insufficient specificity for nucleotide modifications. In this regard, CRISPR-Cas systems have revolutionized molecular diagnostics by offering precise and programmable recognition of nucleic acids (i.e., DNA/RNA). In this review, we specifically explore how integrating CRISPR-Cas systems with electrochemical biosensors can advance biomolecule detection capabilities. First, we outline the fundamental components of electrochemical sensing, followed by a discussion of the key challenges in detecting biomolecules within complex biological environments. Thereafter, we describe the core components and molecular mechanisms of the CRISPR-Cas system and explore how these have been leveraged in electrochemical platforms for detecting disease-specific nucleic acids (DNA and RNA), as well as their emerging potential in protein detection. Next, we highlight approaches to enhance CRISPR-based electrochemical sensing through signal amplification, sensitivity improvement methods, and microfluidic integration. Moreover, we also discuss the growing role of artificial intelligence in improving data interpretation and enhancing CRISPR-based electrochemical sensor diagnostic performance. Finally, we address the broader challenges of implementing CRISPR-Cas-based electrochemical sensor diagnostics and conclude by outlining future perspectives for the development of affordable, scalable, and precise electrochemical diagnostic platforms enabled by CRISPR-Cas technologies.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"56 ","pages":"Article 101813"},"PeriodicalIF":6.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What is the implication of electrons behaving as waves in electrochemically gated molecular structures? 电子在电化学门控分子结构中表现为波的含义是什么？

IF 6.9 2区化学

Current Opinion in Electrochemistry Pub Date : 2026-04-01 Epub Date: 2026-01-19 DOI: 10.1016/j.coelec.2026.101811

Paulo Roberto Bueno

{"title":"What is the implication of electrons behaving as waves in electrochemically gated molecular structures?","authors":"Paulo Roberto Bueno","doi":"10.1016/j.coelec.2026.101811","DOIUrl":"10.1016/j.coelec.2026.101811","url":null,"abstract":"<div><div>Reorganization energy, the energy required to rearrange the system environment during electron transfer, should capture both classical and quantum effects in electrochemically gated molecular structures. This is due to the operation of an isoscopic regime, which can be defined as a situation in which the electrolyte adjusts the classical environmental potential to exactly counterbalance the quantum state charging energy (so <em>E</em> = −<em>E</em><sub><em>e</em></sub>). Traditionally, reorganization energy was defined using classical models. However, recent work demonstrates that quantum concepts provide further insight. For example, quantum capacitance—the ability of a system to store charge in a quantum state—and quantum resistance—resistance arising when electrons behave as waves—help explain reaction rates. The universal value of the quantum resistance, <em>R</em><sub><em>q</em></sub> ≈ 12.9 kΩ, serves as the definitive quantitative evidence of coherent transport. In this context, classical views emerge as a special case of a more general quantum description. Correspondingly, quantum-rate theory, a model that incorporates quantum mechanics into rate calculations, extends earlier frameworks to both electron transfer and quantum transport at room temperature. By broadening the definition of reorganization energy to encompass both classical (<em>E</em><sub><em>e</em></sub>) and quantum (<em>E</em>) states, the overlap between these regimes and the role of quantum coherence—the maintenance of a constant phase relationship between quantum states—in electron transfer and nanoscale electronics becomes clearer. Recognizing this as an isoscopic regime has major implications: it can inform the construction of coherent nanoscale devices and enhance chemical reactions, including catalysis. Adopting this integrated perspective can enable researchers to pursue quantum coherence control in experiments and to design advanced quantum-electrochemical devices.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"56 ","pages":"Article 101811"},"PeriodicalIF":6.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Next-generation polymer interphases for durable zinc anodes: From dendrite suppression to corrosion control 用于耐用锌阳极的下一代聚合物界面：从枝晶抑制到腐蚀控制

IF 6.9 2区化学

Current Opinion in Electrochemistry Pub Date : 2026-04-01 Epub Date: 2026-01-14 DOI: 10.1016/j.coelec.2026.101814

Subir K. Pati , Sambedan Jena , N. Swathi , Prabeer Barpanda

{"title":"Next-generation polymer interphases for durable zinc anodes: From dendrite suppression to corrosion control","authors":"Subir K. Pati , Sambedan Jena , N. Swathi , Prabeer Barpanda","doi":"10.1016/j.coelec.2026.101814","DOIUrl":"10.1016/j.coelec.2026.101814","url":null,"abstract":"<div><div>The practical application of zinc-ion batteries (ZIBs) is constrained by persistent anode instabilities arising from nonuniform Zn nucleation, dendritic growth, corrosion, and parasitic hydrogen evolution. To mitigate these issues, polymer coatings have recently emerged as an effective interfacial engineering approach owing to their tuneable chemistry, mechanical adaptability, and ability to regulate ion transport at the metal-electrolyte boundary. This review summarizes recent advances in polymer-based stabilization strategies for Zn metal anodes, with emphasis on polymers containing coordinating functional groups, polymer-carbon hybrid interphases, and hydrophilic or adhesion-enhanced coatings. We discuss how tailored chemical functionalities-such as carbonyl, pyridyl, amine, and sulfonic groups-govern Zn<sup>2+</sup> adsorption strength, surface charge distribution, desolvation behaviour, and preferred crystallographic growth, enabling controlled Zn deposition. Across these platforms, polymeric interphases demonstrate marked improvements in Coulombic efficiency, overpotential, corrosion resistance, and long-term cycling stability, even at high current densities. The review concludes with key design principles and emerging opportunities for next-generation polymer interfaces aimed at realizing highly reversible, dendrite-free Zn metal anodes for durable aqueous energy storage systems.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"56 ","pages":"Article 101814"},"PeriodicalIF":6.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovations in electrochemical biosensing for health monitoring 用于健康监测的电化学生物传感的创新

IF 6.9 2区化学

Current Opinion in Electrochemistry Pub Date : 2026-04-01 Epub Date: 2026-01-12 DOI: 10.1016/j.coelec.2026.101812

Shweta J. Malode , Abdullah N. Alodhayb , Nagaraj P. Shetti

引用次数: 0

Probing electrochemical solid–solid and solid–liquid interface reaction characteristics based on in-situ technologies and theoretical simulations 基于原位技术和理论模拟的电化学固-固和固-液界面反应特性探测

IF 6.9 2区化学

Current Opinion in Electrochemistry Pub Date : 2026-04-01 Epub Date: 2026-01-20 DOI: 10.1016/j.coelec.2026.101815

Pei-Hua Li , Meng Yang , Wen-Qing Liu , Xing-Jiu Huang

{"title":"Probing electrochemical solid–solid and solid–liquid interface reaction characteristics based on in-situ technologies and theoretical simulations","authors":"Pei-Hua Li , Meng Yang , Wen-Qing Liu , Xing-Jiu Huang","doi":"10.1016/j.coelec.2026.101815","DOIUrl":"10.1016/j.coelec.2026.101815","url":null,"abstract":"<div><div>Electrochemical techniques have emerged as promising approaches for on-site detection and long-term monitoring of metal ions in environmental and biological samples, owing to their rapid response, high sensitivity, and portability. Many efforts have focused on employing various nanomaterials as electrode modifiers to enhance their sensing performance and exploring the detection mechanism. However, most studies remain limited to comparing pre- and post-reaction states of electrode interfaces, paying insufficient attention to the dynamic interfacial processes and <em>real-time</em> structural evolution at solid–solid and solid–liquid interfaces during electroanalysis. A deeper understanding and exploration of solid–solid and solid–liquid interface reaction characteristics, influenced by various factors, including electric fields, environmental conditions, surface state of electrodes, adsorbate species, electrolyte component, and pH value, is essential for purposefully designing highly efficient sensing interfaces. This review highlights recent advances in probing solid–solid and solid–liquid interfacial characteristics and reaction dynamics <em>via in-situ</em> techniques, dynamics simulations, DFT calculations, and machine learning.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"56 ","pages":"Article 101815"},"PeriodicalIF":6.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemical tumor ablation: Applications and future prospects 电化学肿瘤消融：应用及未来展望

IF 6.9 2区化学

Current Opinion in Electrochemistry Pub Date : 2026-04-01 Epub Date: 2026-01-07 DOI: 10.1016/j.coelec.2025.101809

Fei Guo , Xin Song , Kun Qian , Ting Zhu , Qiying Pei

{"title":"Electrochemical tumor ablation: Applications and future prospects","authors":"Fei Guo , Xin Song , Kun Qian , Ting Zhu , Qiying Pei","doi":"10.1016/j.coelec.2025.101809","DOIUrl":"10.1016/j.coelec.2025.101809","url":null,"abstract":"<div><div>Electrochemical tumor ablation, encompassing electrochemical therapy (EchT), irreversible electroporation (IRE), and electroporation and electrolysis (E2), has emerged as a transformative minimally invasive therapy. EchT applies sustained direct current to generate pH gradients (acidic anodes/alkaline cathodes), inducing coagulative necrosis; its procedural simplicity and cost-effectiveness are balanced against tissue dehydration and electrode instability. IRE uses high-voltage pulses to disrupt cell membranes while preserving extracellular matrix integrity, though precise electrode alignment is critical. Emerging protocols like E2 synergize mechanisms of both EchT and IRE to enhance ablation efficacy. Technological advancements, such as bioionic gel electrodes, liquid metal probes, and ultrasound-guided microprobes, improve precision and scalability. Multidisciplinary integration with immunotherapy, reactive oxygen species modulation, and artificial intelligence optimization further boosts outcomes. However, mechanistic ambiguities in electrolytic/electroporation interactions, heterogeneous clinical protocols, and insufficient safety data for novel devices remain critical barriers. Future research needs to prioritize molecular elucidation, multicenter trial validation, and personalized dosing algorithms to advance translational readiness.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"56 ","pages":"Article 101809"},"PeriodicalIF":6.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146045252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ion concentration polarization in small volumes 小体积离子浓度极化

IF 6.9 2区化学

Current Opinion in Electrochemistry Pub Date : 2026-04-01 Epub Date: 2026-01-24 DOI: 10.1016/j.coelec.2026.101818

Beatrise Berzina , Subodha Joris Edirisinghe , Robbyn K. Anand

引用次数: 0

Pulse electrolysis: Temporal innovation for steering CO2RR pathways beyond catalyst design 脉冲电解：引导CO2RR路径超越催化剂设计的时间创新

IF 6.9 2区化学

Current Opinion in Electrochemistry Pub Date : 2026-04-01 Epub Date: 2026-01-13 DOI: 10.1016/j.coelec.2026.101810

Xiaolin Liao , Minghui Quan , Xiang Peng , Abebe Reda Woldu , Liangsheng Hu

{"title":"Pulse electrolysis: Temporal innovation for steering CO2RR pathways beyond catalyst design","authors":"Xiaolin Liao , Minghui Quan , Xiang Peng , Abebe Reda Woldu , Liangsheng Hu","doi":"10.1016/j.coelec.2026.101810","DOIUrl":"10.1016/j.coelec.2026.101810","url":null,"abstract":"<div><div>Electrochemical CO<sub>2</sub> reduction (CO<sub>2</sub>RR) to sustainable fuels and chemicals represents a pivotal strategy for carbon neutrality, yet conventional static methods suffer from limited selectivity, instability, and energy inefficiency. This review examines pulsed CO<sub>2</sub>RR (p-CO<sub>2</sub>RR) as a transformative approach that transcends these limitations by dynamically modulating catalyst microenvironments through temporal control of applied potentials. We first establish the fundamental pulse parameters, potential amplitude, frequency, duty cycle, and period that govern interfacial processes and product distributions. Subsequently, we analyze recent advances in p-CO<sub>2</sub>RR across transition metal catalysts (Cu, Ni, Sn, Fe), highlighting breakthroughs in C<sub>1</sub> (CO, formate, CH<sub>4</sub>) and C<sub>2+</sub> (ethylene, ethanol, branched hydrocarbons) production. By decoupling reaction steps temporally, pulsed strategies enhance Faradaic efficiency, suppress competing hydrogen evolution, and extend catalyst stability. The review concludes with forward-looking perspectives on asymmetric pulse optimization, machine-learning-guided parameter discovery, and scalable reactor designs to accelerate the industrial adoption of dynamic electrocatalysis.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"56 ","pages":"Article 101810"},"PeriodicalIF":6.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146076336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0