Current Opinion in Electrochemistry最新文献

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Implantable electrochemical biosensors: Challenges, strategies, and applications 植入式电化学生物传感器:挑战、策略和应用
IF 6.9 2区 化学
Current Opinion in Electrochemistry Pub Date : 2025-08-19 DOI: 10.1016/j.coelec.2025.101745
Sondes Ben-Aissa, Suryasnata Tripathy, Anthony Edward George Cass
{"title":"Implantable electrochemical biosensors: Challenges, strategies, and applications","authors":"Sondes Ben-Aissa,&nbsp;Suryasnata Tripathy,&nbsp;Anthony Edward George Cass","doi":"10.1016/j.coelec.2025.101745","DOIUrl":"10.1016/j.coelec.2025.101745","url":null,"abstract":"<div><div>Applying biosensor technologies to continuous, real-time measurements in living creatures, including humans, offers an exciting range of possibilities for a better understanding of both normal physiology and disease. It also comes with a collection of technical, ethical and regulatory needs that render the transition of electrochemical biosensors from in vitro to in vivo exceptionally challenging. In this review, we address the advances in the components of implantable electrochemical biosensors. These include the integration of molecular recognition elements, materials design, supply of electrical power, fabrication of instrumentation packages and communications protocols. Significant challenges that remain include those associated with biocompatibility, sterility, device lifetime, calibration and user acceptability. Regulatory aspects whether of medical or consumer devices are essential to address and need to be an early consideration in device design, as are the use cases to which the implanted sensor will ultimately address.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"54 ","pages":"Article 101745"},"PeriodicalIF":6.9,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145046148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Confined electrochemistry in nanocavities: Perspective and techniques 纳米空腔中的受限电化学:观点与技术
IF 6.9 2区 化学
Current Opinion in Electrochemistry Pub Date : 2025-08-14 DOI: 10.1016/j.coelec.2025.101747
Din Zelikovich , Pavel Savchenko , Daniel Mandler
{"title":"Confined electrochemistry in nanocavities: Perspective and techniques","authors":"Din Zelikovich ,&nbsp;Pavel Savchenko ,&nbsp;Daniel Mandler","doi":"10.1016/j.coelec.2025.101747","DOIUrl":"10.1016/j.coelec.2025.101747","url":null,"abstract":"<div><div>The understanding that chemical reactions carried out under nanoconfinement behave significantly differently than in the bulk has motivated electrochemists to study electrochemical processes in nanometer-sized volumes. Significant work has been performed in nanopores where the reactants and products enter and leave at different places. This has been primarily applied to protein and DNA sequencing. Yet, fewer studies have been devoted to studying electrochemical reactions in nanocavities where there is only a single opening. This review summarizes the growing activity in this relatively new area, which includes the approaches for making nanocavities, the ways the nanocavities are analyzed, and the present and future applications.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"54 ","pages":"Article 101747"},"PeriodicalIF":6.9,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decoupling activity and selectivity in catalysis reactions with plasma electrochemical systems 等离子体电化学系统催化反应的去耦活性和选择性
IF 6.9 2区 化学
Current Opinion in Electrochemistry Pub Date : 2025-08-13 DOI: 10.1016/j.coelec.2025.101746
Janiennid Alicea Tirado , Gina DelMonache , Shwetha Prakash, Pratahdeep Gogoi, Xiaoli Ge, Yuguang C. Li
{"title":"Decoupling activity and selectivity in catalysis reactions with plasma electrochemical systems","authors":"Janiennid Alicea Tirado ,&nbsp;Gina DelMonache ,&nbsp;Shwetha Prakash,&nbsp;Pratahdeep Gogoi,&nbsp;Xiaoli Ge,&nbsp;Yuguang C. Li","doi":"10.1016/j.coelec.2025.101746","DOIUrl":"10.1016/j.coelec.2025.101746","url":null,"abstract":"<div><div>Electrochemical systems are considered key technologies for integrating directly with renewable energy sources. However, the development and industrial adoption of certain electrochemical systems are hindered by low efficiencies and current densities, particularly for the activation of inert chemical bonds. Plasma-electrochemical systems have emerged as a transformative approach to overcoming these challenges by decoupling the requirement for bond activation and reaction selectivity. This hybrid configuration allows plasma to drive the activation of strong chemical bonds, while the electrochemical interface controls product formation. As a result, activity and selectivity can be optimized independently, offering a significant advantage over conventional approaches. Plasma-electrochemical systems have been successfully applied in ammonia synthesis, CO<sub>2</sub> reduction, methane activation, and environmental pollutant remediation. This review discusses recent advancements in plasma-electrochemical experimental setups and key chemical mechanisms involved in various catalytic conversions.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"54 ","pages":"Article 101746"},"PeriodicalIF":6.9,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144921562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomedical field applications of electrochemical biosensors as diagnostic tools: A short review 电化学生物传感器作为诊断工具在生物医学领域的应用:简要综述
IF 6.9 2区 化学
Current Opinion in Electrochemistry Pub Date : 2025-08-05 DOI: 10.1016/j.coelec.2025.101738
Ahmet Cetinkaya , S. Irem Kaya , Sibel A. Ozkan
{"title":"Biomedical field applications of electrochemical biosensors as diagnostic tools: A short review","authors":"Ahmet Cetinkaya ,&nbsp;S. Irem Kaya ,&nbsp;Sibel A. Ozkan","doi":"10.1016/j.coelec.2025.101738","DOIUrl":"10.1016/j.coelec.2025.101738","url":null,"abstract":"<div><div>Electrochemical biosensors are preferred in many areas due to their advantages, such as high sensitivity, miniaturization, low cost, and versatility. Early and accurate diagnosis of diseases is the primary step in preventing the spread and progression of the disease and in applying the proper treatment options, which is possible thanks to diagnostic biomarkers. In this context, electrochemical biosensors are practical and effective tools for rapidly and reliably determining biomarkers. Many studies are in the literature due to the versatility of electrochemical biosensors and the ability to improve performance through integration with fields such as nanotechnology and molecular imprinting technology. This short review highlights the most recent and interesting studies on this subject and provides insight into future developments.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"53 ","pages":"Article 101738"},"PeriodicalIF":6.9,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144863195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances in graphene-based electrochemical biosensors for major non-communicable diseases 用于重大非传染性疾病的石墨烯电化学生物传感器的最新进展
IF 6.9 2区 化学
Current Opinion in Electrochemistry Pub Date : 2025-07-25 DOI: 10.1016/j.coelec.2025.101737
Tathagata Bhattacharjya , Martin–Alex Nalepa , Ivan Dědek , Petr Jakubec , David Panáček , Michal Otyepka
{"title":"Recent advances in graphene-based electrochemical biosensors for major non-communicable diseases","authors":"Tathagata Bhattacharjya ,&nbsp;Martin–Alex Nalepa ,&nbsp;Ivan Dědek ,&nbsp;Petr Jakubec ,&nbsp;David Panáček ,&nbsp;Michal Otyepka","doi":"10.1016/j.coelec.2025.101737","DOIUrl":"10.1016/j.coelec.2025.101737","url":null,"abstract":"<div><div>Non-communicable diseases, including cancer, cardiovascular diseases, diabetes, and neurological disorders, represent a growing global health challenge, driving an urgent need for rapid, sensitive, and affordable diagnostic technologies. Graphene-based materials, with their exceptional physicochemical properties, offer transformative potential for the development of next-generation electrochemical biosensors. This review highlights recent advancements in the use of graphene derivatives (such as reduced graphene oxide, graphene quantum dots, laser-induced graphene, and covalently functionalized graphene) for the electrochemical detection of key biomarkers associated with major non-communicable diseases. We critically analyze strategies for enhancing biosensor performance, discuss innovations in biomarker recognition and real-sample validation, and underscore emerging trends toward wearable, minimally invasive platforms. Particular emphasis is placed on the challenges of selectivity, stability, and clinical translation, as well as on the need for reproducible material synthesis and device standardization. By bridging material science with biomedical applications, graphene-based biosensors are poised to enable earlier diagnosis, continuous monitoring, and improved management of non-communicable diseases, ultimately contributing to the advancement of global healthcare.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"53 ","pages":"Article 101737"},"PeriodicalIF":6.9,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144829523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impedimetric aptasensors: Emerging tools for sensitive detection in health, food, and environmental monitoring 阻抗感应传感器:用于健康、食品和环境监测中敏感检测的新兴工具
IF 6.9 2区 化学
Current Opinion in Electrochemistry Pub Date : 2025-07-25 DOI: 10.1016/j.coelec.2025.101736
Arzum Erdem, Huseyin Senturk, Cengiz Altınsoy
{"title":"Impedimetric aptasensors: Emerging tools for sensitive detection in health, food, and environmental monitoring","authors":"Arzum Erdem,&nbsp;Huseyin Senturk,&nbsp;Cengiz Altınsoy","doi":"10.1016/j.coelec.2025.101736","DOIUrl":"10.1016/j.coelec.2025.101736","url":null,"abstract":"<div><div>Electrochemical impedance spectroscopy (EIS)-based aptasensors combine the high selectivity of aptamers as biorecognition elements with the label-free, sensitive, and noninvasive measurement capabilities of EIS. Owing to these features, they have recently attracted considerable attention, offering a wide range of applications from the early diagnosis of numerous biomarkers in the field of healthcare to food safety and environmental analysis. In this review, the fundamental principles of impedimetric aptasensors are discussed, and studies published over the last two years in the fields of health, food, and environment are comprehensively examined. In this context, recent original research on the development of aptasensors for the detection of various analytes including cancer biomarkers, viral and bacterial pathogens, mycotoxins, antibiotic residues, hormones, and heavy metals has been analyzed in detail. Moreover, recent findings supporting the applicability of these aptasensors in complex biological (e.g. serum, plasma, saliva, urine), food (e.g. milk, fruit juice, cereal products), and environmental (e.g. wastewater, river water) sample matrices have been summarized. Additionally, key application-oriented challenges such as optimization of surface chemistry for aptamer immobilization, minimization of matrix effects, sensor surface stability, repeatability/reproducibility, multiplex detection, and integration into portable platforms have been thoroughly discussed. Furthermore, innovative solutions that could facilitate the transition of this technology into clinical and field applications, as well as future perspectives regarding commercialization, have been presented. In this regard, it is emphasized that impedimetric aptasensors possess strong potential not only at the laboratory scale but also as powerful tools for real-world diagnostic and monitoring applications.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"53 ","pages":"Article 101736"},"PeriodicalIF":6.9,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144863194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Next-generation plasma-sprayed electrodes for water electrolysis and beyond: Recent advances and future directions 用于水电解及其他领域的下一代等离子喷涂电极:最新进展和未来方向
IF 6.9 2区 化学
Current Opinion in Electrochemistry Pub Date : 2025-07-22 DOI: 10.1016/j.coelec.2025.101732
Glen McClea , Laura Titheridge , Steven Matthews , Aaron T. Marshall
{"title":"Next-generation plasma-sprayed electrodes for water electrolysis and beyond: Recent advances and future directions","authors":"Glen McClea ,&nbsp;Laura Titheridge ,&nbsp;Steven Matthews ,&nbsp;Aaron T. Marshall","doi":"10.1016/j.coelec.2025.101732","DOIUrl":"10.1016/j.coelec.2025.101732","url":null,"abstract":"<div><div>Conventional industrial alkaline water electrolysis electrodes made using plasma spray deposition are unable to produce and sustain the demanding performance requirements needed to achieve economic targets. State-of-the-art lab-scale alkaline electrolysis configurations can achieve these higher performances; however, given their complex electrode architecture and production methods, often suffer from practical limitations regarding scale-up. Proven and trusted by industry, plasma spraying offers a pragmatic and cost-effective method for fabricating these next-generation electrodes at scale. This review explores the most recent advances in plasma-sprayed electrode development, covering its use to form both the active catalyst layer and the porous transport layer. We also highlight how these findings can be transferred to benefit the development of other industrial process electrodes. This review aims to provide pathways for future research, showing how novel lab-scale electrodes can be replicated at scale, with the latest in plasma-spray technology.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"53 ","pages":"Article 101732"},"PeriodicalIF":6.9,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144828230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shaping the next-generation of fused deposition modeling three-dimensional-printing-based electrochemical (bio)sensing: Drawing a realistic horizon 塑造下一代熔融沉积建模三维打印电化学(生物)传感:绘制现实的地平线
IF 6.9 2区 化学
Current Opinion in Electrochemistry Pub Date : 2025-07-15 DOI: 10.1016/j.coelec.2025.101730
Miriam Chávez , Fabiana Arduini , Alberto Escarpa
{"title":"Shaping the next-generation of fused deposition modeling three-dimensional-printing-based electrochemical (bio)sensing: Drawing a realistic horizon","authors":"Miriam Chávez ,&nbsp;Fabiana Arduini ,&nbsp;Alberto Escarpa","doi":"10.1016/j.coelec.2025.101730","DOIUrl":"10.1016/j.coelec.2025.101730","url":null,"abstract":"<div><div>The emergence of three-dimensional (3D)-printing as a fabrication tool has revolutionized the development of customized electrochemical (bio)sensors, offering exceptional design flexibility, cost-effective and rapid prototyping. Among the additive manufacturing technologies, fused deposition modeling (FDM) stands out for its affordability, ease of use, and the growing availability of conductive filaments, providing a new approach to produce tailored electrodes with enormous analytical potential and capabilities. This perspective presents a critical overview of the current opportunities and limitations of FDM-3D-printing as a technology for the design and development of electrochemical (bio)sensors, addressing material formulation, electrode architecture, surface modification strategies, analytical performance, and emerging applications. Current challenges and directions to overcome them are identified and discussed, drawing a realistic horizon for the next generation of FDM-3D-printed electrochemical (bio)sensors.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"53 ","pages":"Article 101730"},"PeriodicalIF":6.9,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Local pH engineering to impact electrocatalysis 局部pH工程影响电催化
IF 6.9 2区 化学
Current Opinion in Electrochemistry Pub Date : 2025-07-09 DOI: 10.1016/j.coelec.2025.101728
Maxime Decker , Quentin Lenne , Jalal Ghilane , Carlos M. Sánchez-Sánchez
{"title":"Local pH engineering to impact electrocatalysis","authors":"Maxime Decker ,&nbsp;Quentin Lenne ,&nbsp;Jalal Ghilane ,&nbsp;Carlos M. Sánchez-Sánchez","doi":"10.1016/j.coelec.2025.101728","DOIUrl":"10.1016/j.coelec.2025.101728","url":null,"abstract":"<div><div>Local pH refers to the pH gradient developed within the diffusion layer of the electrode, which can deviate significantly from the bulk value due to proton consumption or generation during electrocatalytic reactions. The proton availability is often a thermodynamic or kinetic limiting factor during electrocatalytic reactions involving proton–electron transfer as the determining step. Thus, controlling local pH can effectively impact both reaction selectivity and activity. In this short review, we present recent advances and strategies that emerged to effectively tune the local pH and impact on different electrocatalytic reactions, such as CO<sub>2</sub> reduction reaction (CO<sub>2</sub>RR), electrochemical nitrate reduction (ENR), O<sub>2</sub> reduction reaction, (ORR) and ethanol oxidation reaction (EOR). The catalyst engineering approach through microenvironment modification, tuning mass transport conditions by catalyst size and porosity, as well as by pulsed potential electrolysis are the strategies described here.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"53 ","pages":"Article 101728"},"PeriodicalIF":6.9,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnetic support-driven electrochemical affinity biosensing: Advancing sensitive, rapid, and simplified determination of clinically relevant analytes 磁支持驱动的电化学亲和生物传感:推进敏感,快速和简化的测定临床相关分析物
IF 7.9 2区 化学
Current Opinion in Electrochemistry Pub Date : 2025-07-08 DOI: 10.1016/j.coelec.2025.101729
Susana Campuzano , Maria Gamella , José M. Pingarrón
{"title":"Magnetic support-driven electrochemical affinity biosensing: Advancing sensitive, rapid, and simplified determination of clinically relevant analytes","authors":"Susana Campuzano ,&nbsp;Maria Gamella ,&nbsp;José M. Pingarrón","doi":"10.1016/j.coelec.2025.101729","DOIUrl":"10.1016/j.coelec.2025.101729","url":null,"abstract":"<div><div>The demand to determine analytes at increasingly lower concentrations in complex samples, while minimizing sample size, treatment and test duration, has driven innovation in electrochemical biotechnologies. Inspired by the principle that affinity reactions gain in efficiency and speed when the biosensing surface seeks the analyte, bioelectrochemical technologies leverage their unique strengths along with those provided by magnetic carriers to improve affinity testing, pushing the boundaries of accuracy and efficiency.</div><div>This minireview focuses primarily on magnetic beads, motors, and gold-coated magnetic nanoparticles dispersible electrodes, considering the remarkable improvements they provide in electrochemical affinity biotechnologies. A timely, comparative, and critical analysis of the opportunities offered by these three magnetic supports in electrochemical affinity biodetection is carried out by highlighting and discussing some of the most innovative research. This minireview also dares to forecast the future potential of these technologies for advancing modern analytical capabilities and accelerating their integration into next-generation point-of-care devices.</div></div>","PeriodicalId":11028,"journal":{"name":"Current Opinion in Electrochemistry","volume":"53 ","pages":"Article 101729"},"PeriodicalIF":7.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144711096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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