Current Traditional Medicine最新文献

{"title":"Important Regulatory Guidelines on Natural Products","authors":"Abhisar Sahu, Nimisha srivastava, Devashish Jena, Aayushee Singh, Satya Kumar, Iti Chauhan","doi":"10.2174/0122150838226206230922043839","DOIUrl":"https://doi.org/10.2174/0122150838226206230922043839","url":null,"abstract":"Abstract: Ayurvedic cosmeceuticals are alluded to as products of various passable magnificence substances to shape the base in which one or more ayurvedic parts are utilized to give benefits and various ailments. The Drugs and Cosmetics Act of 1940 controls the approaches concerning the making, dealing, amassing, allotment, and importing of drugs in essentially a comparable manner to radiance care things in India. Quality control and assessment of Ayurvedic drugs must ensure the effectiveness of the drug. Given their crucial role, it involves evaluating their physical, chemical, and physiochemical qualities, as well as conducting in-vitro and in-vivo tests. Natural ingredients have consistently been our primary source of medicines, and dosage forms determine how drug molecules or plant components are delivered to the site of action within the body. Good agricultural and collection practices (GACP) rules have been given by the WHO (World Health Organization) for the differentiation and planning of regular items. There are primarily two legal regulatory bodies within the AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) sector i.e., Central Council of Indian Medicine (CCIM) and the Central Council of Homeopathy.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135618642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Woodfordia fruticosa (L. Kurz): An Evidence-based Study of Its Phytochemical and Pharmacological Activity","authors":"Kuldeep Singh, Jeetendra Kumar Gupta, Devender Pathak, Shivendra Kumar, Ateet Srivastava, Avinash Kumar Mishra, Aman Patel, Harshit Prajapati","doi":"10.2174/0122150838258736231007045743","DOIUrl":"https://doi.org/10.2174/0122150838258736231007045743","url":null,"abstract":"Abstract: Woodfordia fruticosa (L.) Kurz, a member of the 'Lythraceae' family, has been used in traditional medicine to cure common diseases since ancient times. It is traditionally used to treat a variety of maladies such as the common cold, toothache, blood infection, leprosy, dysentery, wounds, rheumatic pain, fever, urinary issues, inflammation, antifertility, and menstrual problems. The huge potential and impacts of this plant have been thoroughly confirmed in in vitro and in vivo studies. The most current research on the plant Woodfordia fruticosa is critical for identifying the bioactive components responsible for its medicinal efficacy. Phytochemical studies reveal the existence of several chemicals extracted from various components of the plant, including glycosides, terpenes, flavonoids, tannins, sterols, phenolics, and essential oils. According to pharmacological studies, the plant has many medicinal properties, such as hypoglycemic, antioxidant, analgesic, hepatoprotective, antibacterial, gastric protective, and wound healing. Most of the pharmacological effects of raw extracts of this plant have been described. Only a few researchers have reported the activity of chemicals isolated from this plant. Therefore, this research will help to discover the many different medicinal properties of the plant as well as its pharmacological effects on various diseases and will show that further research is needed to explore its practical applications.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135618409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nature’s Signature in Ayurveda with an Ethnopharmacological Approach: A Narrative Review","authors":"Acharya Balkrishna, Shalini Mishra, Rajesh Kumar Mishra, Maneesha Rana, Shalini Singh, Vedpriya Arya","doi":"10.2174/0122150838270781231006184609","DOIUrl":"https://doi.org/10.2174/0122150838270781231006184609","url":null,"abstract":"Abstract: The nature's signature in Āyurveda i.e. Doctrine of Signatures (DOS), which calls for utilizing natural substances that resemble a particular body part or organ, is consistent with the ethnopharmacological practice of choosing therapeutic plants based on their visible physical qualities. In order to promote health and treat ailments, the ancient Indian medical system known as Āyurveda employs natural ingredients including plants, minerals, and animal products. The study of conventional medicine and the application of natural products for therapeutic reasons are known as ethno-pharmacology. This review explores various research on ayurvedic herbs, their doctrinal signature, and the status of our understanding of ethno-pharmacology. However, by integrating Āyurveda plants' doctrinal signatures with ethnopharmacological methods, it might be better to comprehend the therapeutic potential of plants and create novel treatments for a range of ailments. Combining these two perspectives might assist in understanding how nature may heal and how natural medicines could improve health and wellness. It was believed that a plant containing parts that resembled portions of human bodies, animals, or other items had practical use for those parts, animals, or objects. This philosophy was shown in some of the Indian medicinal plants that are discussed in this article.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135619999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gallic Acid: A Wonderful Remedy in Medicinal Field","authors":"Anmol saini, Vishakha D. Saini, Renu Saharan, Suresh Kumar","doi":"10.2174/0122150838266828231005055236","DOIUrl":"https://doi.org/10.2174/0122150838266828231005055236","url":null,"abstract":"Abstract: GA (Gallic acid) belongs to the phenolic molecule that is naturally present in plants, and has an assortment of medicinal benefits on inflammation, obesity, cancer, the heart, neurological system, and the proliferation of cells. In more recent research, the anti-cancer effects via biological mechanisms such as angiogenesis, migration, metastasis, cell cycle arrest, and apoptosis have been demonstrated. Anti-cancer activities of gallic acid are affected through the biological methods which involve reluctance of tumor migration, inflammation, etc. Numerous degenerative diseases, namely blood-vascular, ageing, inflammatory contagion and malignancy are brought on owing to the free radical damage because of the excess amount of free radicals produced and accretion. We carried out a comprehensive examination of the literature employing the expression of gallic acid. To review the most current advancements and clinical investigations for the pharmacological effects of gallic acid, recognized research from various reputable organizations and sites including Scopus, ClinicalTrails.gov, Science Direct, and PubMed were analyzed. This review, which offers a succinct description of gallic acid, updates the contents of clinical research and patent data, it brings forth the elaborate attainment regarding the various abundant therapeutic efficacies along with the extraction methodology of the drug that is used to obtain it, including microwave-assisted extraction and maceration extraction, among others, as well as non-chromatographic and chromatographic techniques for its isolation and quantification. Antifungal, antiulcer, antiviral, anticancer, and antibacterial properties are just a few of the pharmacological effects of naturally occurring gallic acid.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136213247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Nanoparticulate Cosmeceuticals: Boon for Hyperpigmentation","authors":"Prashant L. Pingale, Rupali A. Patil, Anjali P. Bedse, Shilpa S. Raut","doi":"10.2174/0122150838266844230927052225","DOIUrl":"https://doi.org/10.2174/0122150838266844230927052225","url":null,"abstract":"Abstract: Recently nanotechnology has emerged with more attention to the cosmetic industry. Formulations for skin whitening are widely applied but hyperpigmentation treatment remains unnoticed. This review summarises use of nanotechnology in hyperpimentaion. Various organic and inorganic nanoparticles used in cosmeceuticals are explained. Various approaches for treatment of hyperpigmentation, barriers for Nanodelivery, availability of organic and inorganic synthetic nanoparticles are stated in the study. The advantages and disadvantages of these organic and inorganic compounds are enlisted. Special emphasis has been given to natural substances including arbutin, Aloesin, hesperidin, niacinamide, liquorice, mulberry, polyphenols, ginseng, gingko which are used used in hyperpigmentation. Regulatory challenges and issues for clinical translation, Patents and publications available in last 20 years related to nanotechnology in hyperpigmentation are discussed in brief. It has been observed that amongst nanocosmeceuticals used for hyperpigmentation, lipid nanoparticles are most widely used due to more skin permeability, biocompatibility, and biodegradable nature. Nonetheless, investigation on health effects and safety profile of nanomaterials are essential for understanding the impact of using these materials.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"255 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136213371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of COVID-19 Pandemic by Immunity-modulating Ayurvedic Interventions: A Bright Panacea","authors":"Ruchi Sharma, Shalini Rai, Heena Saini, Dimpal Rochlani, Varnika Singh, Richa Tripathi","doi":"10.2174/0122150838262609231003071619","DOIUrl":"https://doi.org/10.2174/0122150838262609231003071619","url":null,"abstract":"Abstract: COVID-19, or SARS-CoV-2 or novel coronavirus 2019 (nCoV-2019), first reported in Wuhan, China, has become a global pandemic due to human-to-human transmission with no specific treatment available. This review highlights the history of coronavirus, its diagnosis, treatment, and prevention by immunity-modulating Ayurvedic interventions to manage the disease during the early chaotic days of the COVID-19 outburst. Immunity modulation is a documented mode of action for many Ayurvedic drugs, including Tinospora cordifolia, Withania somnifera, Andrographis paniculata, Glycerrhiza glabra, Boerhaevia diffusa, Ocimum sanctum, Tribulus terrestris, Curcuma longa, Emblica officinalis, Terminalia chebula, Terminalia bellirica, etc. Several studies have been performed, and many trials have been registered to evaluate the effects of these herbal drugs to combat infectious diseases like COVID-19. Studies have also shown that Ayurvedic drugs, healthy diet, good lifestyle, and psychological aspects all have been researched over the years and found to have a significant role in increasing immunity and decreasing the number of comorbidities; hence, they should be considered in designing a module for the prevention and treatment of COVID-19 infection.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"255 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136213246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical, Ethnobotanical, and Global Perspectives of Genus Echinacea: A Panoramic Review","authors":"Disha Arora, Smriti Parashar, Rupesh K. Gautam, Rajat Goyal","doi":"10.2174/0122150838260749230926072326","DOIUrl":"https://doi.org/10.2174/0122150838260749230926072326","url":null,"abstract":"Nature has always been a wonderful supply of therapeutic substances, providing us\u0000with a range of medicinal plants that produce helpful phytochemicals. The native species of the\u0000genus Echinacea, which are found in North America and are well-known among medicinal\u0000plants, are members of the Asteraceae family. Though there are nine different species of echinacea, only three Echinacea angustifolia DC, Echinacea purpurea (L.) Moench, and Echinacea\u0000pallida (Nutt.)-are utilized as medicinal herbs with a variety of therapeutic uses. Contrary to other plant families, the Asteraceae family of plants is one of the most well-known and renowned,\u0000and as a result, many of its members have been employed for therapeutic purposes. The availability of substances with a variety of medicinal characteristics is to blame for this. This review\u0000has included the investigation of the morphological traits, ethnopharmacology, and diverse\u0000pharmacological properties of the Echinacea genus. The chemistry of the genus is extensively\u0000understood, and various chemical component groups-including alkamides and caffeic acid derivatives-are believed to be crucial for activity.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136213370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnopharmacological Insights on Therapeutic Potential of Oleanolic Acid: A Review","authors":"None Hemlata, Neeru Vasudeva, Sunil Sharma, Archana Kapoor","doi":"10.2174/2215083810666230914165353","DOIUrl":"https://doi.org/10.2174/2215083810666230914165353","url":null,"abstract":"Introduction: Plants have long been utilised as a supplement or alternative treatment for chronic conditions due to their therapeutic capabilities. Objectives: The objective of this study is to explore the ethnopharmacological aspects and therapeutic potential of naturally occurring oleanolic acid. Method: Information regarding oleanolic acid was collected from electronic databases, such as ScienceDirect, Web of Science, PubMed, Springer, Journal websites, Google Scholar, Taylor and Francis, Scopus and Wiley Online Library. Result: The article covered a wide range of immunomodulatory, antihypertensive, anticancer, antiinflammatory, antianxiety, antidepressant, antiischemic, antiviral, and other effects of triterpenoids. One such triterpenoid is oleanolic acid, which was reported to be present in a number of plants with a wide range of pharmacological potential. This article discussed the promising possibilities for alternative neurodegenerative disease treatment and management through oleanolic acid and its derivatives. Conclusion: The goal of this systematic review was to review the medicinal importance of oleanolic acid, extracted from a variety of plants used as a dietary source, such as apple, pomegranate, lemon, grapes, pears, olive, a highly powerful molecule with a wide range of biological actions, such as anti-microbial, anti-viral, anti-diabetic, hepatoprotective, antihypertensive, antiinflammatory, anticancer, anti-ischemic, antiviral, and cytotoxic properties.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"109 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136254753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical Mapping to Comprehend the Bioactivity of Bixa orellana L.","authors":"Mamta Thakur, Rashmi Saxena Pal, Yogendra Pal, MVNL Chaitanya","doi":"10.2174/0122150838261199230925055621","DOIUrl":"https://doi.org/10.2174/0122150838261199230925055621","url":null,"abstract":"Abstract: The \"lipstick tree\" is another name for the ornamental plant Bixa orellana L., which is indigenous to South and Central America, the Caribbean Islands, and other regions of Asia. The plant, also known as \"Sinduri\" or \"Latkan,\" is utilized in India's food, dye, cosmetics, and traditional medicine sectors. Commercially, the plant seeds are significant because they yield bixin, a carotenoid that colours dairy products and is used to manufacture \"sindur\" and \"lipstick.\" The primary substances present in various portions of this plant include carotenoids, apo carotenoids, terpenes, terpenoids, sterols, and aliphatic chemicals. The various plant parts exhibit a variety of possible health advantages, including antibacterial, anti-hyperglycemic, anti-histaminic, anti-diarrheal, anti-cancer, anti-inflammatory, and antioxidant qualities. The current study provides an overview of Bixa orellana L.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136358651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Yoga and Meditation in the Treatment of Neurological and Psychiatric Disorders","authors":"Debabrata Ghosh Dastidar, Payel Bhattacharjee, Pratyush Das, Bachaspati Jana, Anirban Bhunia","doi":"10.2174/0122150838246321231003015837","DOIUrl":"https://doi.org/10.2174/0122150838246321231003015837","url":null,"abstract":"Background:: According to the Global Burden of Disease (GBD) study, the global health impact of neurological and psychiatric disorders has been underestimated for years. Neuropsychiatric disorders are now recognised as significant threats to public health. In conjunction with modern pharmaceutical interventions, the clinical application of yoga and meditation techniques has been increasingly recognised for their efficacy in treating various mental health conditions. Objective:: This article aimed to provide a comprehensive review summarizing the influence of yoga and meditation on the human brain, specifically focusing on their clinical implementation for neurological and psychiatric disorders. Methods:: A systematic search was conducted across PubMed and Google Scholar databases utilizing diverse combinations of keywords, including yoga, meditation, neurogenesis, neurological disorder, mental health, mindfulness, thought process, neuroimaging, and brain, to identify pertinent literature for this review. Results:: Prevalent neurological and psychiatric ailments in our society encompass multiple sclerosis, epilepsy, migraine, fibromyalgia, cerebrovascular disease, Alzheimer's disease, major depression, anxiety disorder, and chronic stress. Scientifically corroborated by clinical studies, the advantageous effects of yoga and spiritual practices on these disorders have been substantiated. As our understanding of the complex psychology and functionalities of the human brain progresses, it becomes apparent that yoga and meditation facilitate neurogenesis and restore chemical equilibrium. Such practices aid in dispelling intrusive thoughts, negating negative emotions, and ameliorating stress, thereby offering relief to patients and progressively diminishing their reliance on conventional medication. Conclusion:: The integration of yoga and spiritual practices as complementary and non-invasive adjunctive therapies represents a promising approach to addressing the spectrum of neurological disorders plaguing modern society.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"2015 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136358100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}