Ethnopharmacological Insights on Therapeutic Potential of Oleanolic Acid: A Review

IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Current Traditional Medicine Pub Date : 2023-10-10 DOI:10.2174/2215083810666230914165353

None Hemlata, Neeru Vasudeva, Sunil Sharma, Archana Kapoor

{"title":"Ethnopharmacological Insights on Therapeutic Potential of Oleanolic Acid: A Review","authors":"None Hemlata, Neeru Vasudeva, Sunil Sharma, Archana Kapoor","doi":"10.2174/2215083810666230914165353","DOIUrl":null,"url":null,"abstract":"Introduction: Plants have long been utilised as a supplement or alternative treatment for chronic conditions due to their therapeutic capabilities. Objectives: The objective of this study is to explore the ethnopharmacological aspects and therapeutic potential of naturally occurring oleanolic acid. Method: Information regarding oleanolic acid was collected from electronic databases, such as ScienceDirect, Web of Science, PubMed, Springer, Journal websites, Google Scholar, Taylor and Francis, Scopus and Wiley Online Library. Result: The article covered a wide range of immunomodulatory, antihypertensive, anticancer, antiinflammatory, antianxiety, antidepressant, antiischemic, antiviral, and other effects of triterpenoids. One such triterpenoid is oleanolic acid, which was reported to be present in a number of plants with a wide range of pharmacological potential. This article discussed the promising possibilities for alternative neurodegenerative disease treatment and management through oleanolic acid and its derivatives. Conclusion: The goal of this systematic review was to review the medicinal importance of oleanolic acid, extracted from a variety of plants used as a dietary source, such as apple, pomegranate, lemon, grapes, pears, olive, a highly powerful molecule with a wide range of biological actions, such as anti-microbial, anti-viral, anti-diabetic, hepatoprotective, antihypertensive, antiinflammatory, anticancer, anti-ischemic, antiviral, and cytotoxic properties.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"109 1","pages":"0"},"PeriodicalIF":0.6000,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Traditional Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/2215083810666230914165353","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction: Plants have long been utilised as a supplement or alternative treatment for chronic conditions due to their therapeutic capabilities. Objectives: The objective of this study is to explore the ethnopharmacological aspects and therapeutic potential of naturally occurring oleanolic acid. Method: Information regarding oleanolic acid was collected from electronic databases, such as ScienceDirect, Web of Science, PubMed, Springer, Journal websites, Google Scholar, Taylor and Francis, Scopus and Wiley Online Library. Result: The article covered a wide range of immunomodulatory, antihypertensive, anticancer, antiinflammatory, antianxiety, antidepressant, antiischemic, antiviral, and other effects of triterpenoids. One such triterpenoid is oleanolic acid, which was reported to be present in a number of plants with a wide range of pharmacological potential. This article discussed the promising possibilities for alternative neurodegenerative disease treatment and management through oleanolic acid and its derivatives. Conclusion: The goal of this systematic review was to review the medicinal importance of oleanolic acid, extracted from a variety of plants used as a dietary source, such as apple, pomegranate, lemon, grapes, pears, olive, a highly powerful molecule with a wide range of biological actions, such as anti-microbial, anti-viral, anti-diabetic, hepatoprotective, antihypertensive, antiinflammatory, anticancer, anti-ischemic, antiviral, and cytotoxic properties.

查看原文本刊更多论文

齐墩果酸治疗潜力的民族药理学研究综述

植物长期以来一直被用作慢性疾病的补充或替代治疗，因为它们的治疗能力。目的:本研究的目的是探索天然齐墩果酸的民族药理学方面和治疗潜力。方法:从ScienceDirect、Web of Science、PubMed、Springer、Journal websites、Google Scholar、Taylor and Francis、Scopus和Wiley Online Library等电子数据库收集齐墩果酸相关信息。结果:三萜具有广泛的免疫调节、降压、抗癌、抗炎、抗焦虑、抗抑郁、抗缺血、抗病毒等作用。齐墩果酸就是这样一种三萜，据报道，齐墩果酸存在于许多植物中，具有广泛的药理潜力。本文讨论了齐墩果酸及其衍生物治疗和管理神经退行性疾病的可能性。结论:本系统综述的目的是回顾齐墩果酸的药用价值，它是从多种植物中提取的，如苹果、石榴、柠檬、葡萄、梨、橄榄等，是一种具有广泛生物作用的强效分子，如抗微生物、抗病毒、抗糖尿病、保肝、抗高血压、抗炎、抗癌、抗缺血、抗病毒和细胞毒性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Traditional Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Current Traditional Medicine covers all the aspects of the modernization and standardization research on traditional medicine of the world, e.g. chemistry, pharmacology, molecular mechanism, systems biology, proteomics, genomics, metabolomics, safety, quality control, clinical studies of traditional Chinese, Ayurvedic, Unani, Arabic and other ethnomedicine. Each issue contains updated comprehensive in-depth/mini reviews along with high quality original experimental research articles. Current Traditional Medicine is a leading and important international peer-reviewed journal reflecting the current outstanding scientific research progresses of the global traditional, indigenous, folk and ethnologic medicine. It provides a bridge connected the tradition medicine system to the modern life science with the efforts of top scientists, as well as a resource to pursuit the solutions for the existing common issues in the traditional medicine.