Current Traditional Medicine最新文献

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Li Qi Huo Xue Di Wan Attenuates Cardiac and Lung Injury in Mice Exposed to Hypoxia Through Suppression of Apoptosis 利气活血地丸通过抑制细胞凋亡减轻缺氧小鼠心肺损伤
Current Traditional Medicine Pub Date : 2025-02-13 DOI: 10.2174/0122150838341550250121114736
Yiyue Zhang, Chao Zhuang, Can Tang, Qi-Ling Dou, Xiu‐Ju Luo, Xiu‐Ju Luo, Jun Peng
{"title":"Li Qi Huo Xue Di Wan Attenuates Cardiac and Lung Injury in Mice Exposed to Hypoxia Through Suppression of Apoptosis","authors":"Yiyue Zhang, Chao Zhuang, Can Tang, Qi-Ling Dou, Xiu‐Ju Luo, Xiu‐Ju Luo, Jun Peng","doi":"10.2174/0122150838341550250121114736","DOIUrl":"https://doi.org/10.2174/0122150838341550250121114736","url":null,"abstract":"Background: Li Qi Huo Xue Di Wan (LQHXDW), a traditional Chinese medicine, is used to treat patients with the symptoms of palpitations, chest tightness, chest pain, and shortness of breath. It is not known, however, whether LQHXDW can reduce high-altitude hypoxia-induced cardiopulmonary injury, what are the specific active ingredients, and what is the exact mechanism behind its cardiopulmonary protection. Objectives: This study intends to investigate the effect of LQHXDW on hypoxia-induced cardiopulmonary injury and the underlying mechanisms. Methods: The components of LQHXDW were identified by UPLC-QTOF-MS. The potential targets of LQHXDW against high-altitude hypoxia were screened via network pharmacology. Mice were subjected to an animal hypoxic chamber for 5 days to establish a high-altitude hypoxia animal model. Rat heart-derived H9c2 cells and human pulmonary artery endothelial cells (HPAECs) were cultured in glucose-free medium under hypoxic conditions (O2 /N2 /CO2, 3/92/5) for 72 h to mimic the high-altitude hypoxia in vivo. Results: The study found that LQHXDW can target apoptosis and inflammation pathways under the condition of high-altitude hypoxia . In mice exposed to hypoxia, LQHXDW reduced cardiac and lung injury, decreased inflammatory responses, and improved cardiac function. In vitro, LQHXDW increased cell viability and reduced apoptosis in cardiomyocytes and pulmonary artery endothelial cells. It also inhibited the activities of caspase-8 and caspase-3, preventing cardiopulmonary apoptosis. Discussion: The study investigates the impact of LQHXDW on hypoxia-induced heart and lung injury using UPLC-QTOF-MS and animal and cell models. Results show that LQHXDW can attenuate injury, prevent apoptosis, and protect the heart and lungs from hypoxia injury. It also demonstrates anti-inflammatory activity, suggesting LQHXDW as a potential candidate for traditional Chinese medicine in high-altitude sickness treatment. Conclusion: LQHXDW can be used as a potential inhibitor of apoptosis for treating high-altitude hypoxia. This study provided a clue for future studies to identify the exact active components of LQHXDW for targeting the pathways of apoptosis.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147917435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Overview of Traditional Chinese Medicine Nursing for Patients with COVID-19 新型冠状病毒肺炎患者的中医药护理综述
Current Traditional Medicine Pub Date : 2025-01-07 DOI: 10.2174/0122150838304552241129094342
Ping Chen, Baibai Ye, Cheng Lin, Jia Chen, Chunping Xia, Linfu Li
{"title":"An Overview of Traditional Chinese Medicine Nursing for Patients with COVID-19","authors":"Ping Chen, Baibai Ye, Cheng Lin, Jia Chen, Chunping Xia, Linfu Li","doi":"10.2174/0122150838304552241129094342","DOIUrl":"https://doi.org/10.2174/0122150838304552241129094342","url":null,"abstract":"COVID-19 is a severe challenge facing the world today and poses a serious threat to the global public health security. Traditional Chinese medicine (TCM) nursing has played an active role in the treatment and prevention of COVID-19. This study investigated the role of the TCM in the nursing of COVID-19 patients, aiming to provide a comprehensive understanding of its effectiveness and application. This article conducted a systematic review of recent studies and clinical cases, analyzed the theoretical basis of TCM nursing for COVID-19, explored the role of TCM nursing in COVID-19 prevention and control from multiple perspectives, such as Chinese medicine treatment, acupuncture and massage treatment, and clinical nursing. Findings indicated that TCM nursing interventions significantly improved patient recovery rates, reduced symptoms, and enhanced overall well-being. In TCM clinical practice, clearing heat, herbs resolving dampness, and relieving exterior symptoms are commonly used. These are complemented by phlegm-resolving, Qi-regulating, and purgative herbs. Acupoints that can serve to support the body's righteousness and attempt to eliminate evil are very common.. Massage should mainly affect the lung meridian and its interior counterpart, the large intestine meridian, as well as regulate the Zhongjiao and overall body condition through the spleen, stomach, and Ren-Du meridians. Clinical nursing should not only address symptoms closely related to COVID-19, such as fever and respiratory issues, but also consider digestion, sleep, and emotions of the patient. TCM nursing provided a valuable complement to conventional treatments for COVID-19, emphasizing the need for further integration of TCM practices in global health strategies.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"11 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147880476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Exploring the Anti-melanogenic, Antioxidant, and Anti-inflammatory Activities of a Composition: Glabridin, Resveratrol and Ellagic Acid 光甘草定、白藜芦醇和鞣花酸的抗黑素、抗氧化和抗炎活性研究
Current Traditional Medicine Pub Date : 2024-12-02 DOI: 10.2174/0122150838296794240610130259
Jie Huang, Chong Xie, Zhi Quan Pan, Mengya Lin, Qingsheng Chen, Shengzhao Gong, Shengzhao Gong, Yadong Huang
{"title":"Exploring the Anti-melanogenic, Antioxidant, and Anti-inflammatory Activities of a Composition: Glabridin, Resveratrol and Ellagic Acid","authors":"Jie Huang, Chong Xie, Zhi Quan Pan, Mengya Lin, Qingsheng Chen, Shengzhao Gong, Shengzhao Gong, Yadong Huang","doi":"10.2174/0122150838296794240610130259","DOIUrl":"https://doi.org/10.2174/0122150838296794240610130259","url":null,"abstract":"Background: Plant extracts have wide applications in food, nutrition, and cosmetics, which results in a deeper investigation of natural ingredients. Numerous natural ingredients have been demonstrated to exhibit multiple activities, including antioxidation, anti-inflammation, and anti-melanogenesis. However, their combinations have not been well investigated, which could provide stronger performance with less toxicity and easier applications. Methods: We used B16F10 cells treated with alpha-melanocyte stimulating hormone (αMSH) for melanogenesis-related studies, including cellular melanin content, tyrosinase activity, and gene or protein expression. MTT assay was used to evaluate cell viability. DPPH scavenging activity was measured for antioxidation. Nitric oxide (NO) content was evaluated in lipopolysaccharide (LPS) treated RAW264.7 cells to indicate the performance on anti-inflammation. Results: In this study, six different compounds and their combinations were tested for melanogenesis. The results showed that the combination of glabridin, resveratrol, and ellagic acid (GRE) exhibited the highest efficiency, which was mainly manifested as inhibition of melanin production and tyrosinase activity, higher DPPH scavenging rate, and inhibition of nitric oxide (NO) production. Meanwhile, our results showed that GRE could significantly downregulate the expression of microphthalmia-associated transcription factor (MITF) related genes and proteins and could also inhibit the phosphorylation of cyclic AMP response element-binding protein (CREB), which was the upstream signal of MITF. Conclusion: The results suggest GRE exhibits high efficiency in inhibiting anti-melanogenesis, antioxidation, and anti-inflammation. Furthermore, GRE could downregulate the phosphorylation of the CREB and MITF signal pathway, which provides a theoretical basis for its application in pigmentation disorder disease and cosmetics.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"11 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Yinxieling Inhibits Keratin 17 to Enhance Mitochondrial Function and Ameliorates Psoriasis-like Lesions 银泻灵抑制角蛋白17增强线粒体功能,改善银屑病样病变
Current Traditional Medicine Pub Date : 2024-10-24 DOI: 10.2174/0122150838312001241002094020
Shilei Wang, Helin Pan, Chenxi Zhao, Wanqun Chen, Jinwei Zhang
{"title":"Yinxieling Inhibits Keratin 17 to Enhance Mitochondrial Function and Ameliorates Psoriasis-like Lesions","authors":"Shilei Wang, Helin Pan, Chenxi Zhao, Wanqun Chen, Jinwei Zhang","doi":"10.2174/0122150838312001241002094020","DOIUrl":"https://doi.org/10.2174/0122150838312001241002094020","url":null,"abstract":"Background: Psoriasis is a chronic skin disease characterized by erythema, scaling, and thickening. Yinxieling is a representative prescription for treating psoriasis developed by Professor Guowei Xuan, a master of traditional Chinese medicine. Keratin 17 is a key biomarker for the diagnosis and treatment of psoriasis, and its overexpression has been shown to impair mitochondrial function. Objectives: This study investigates the mechanism of action of Yinxieling in the treatment of psoriasis. Methods: In vivo, BALB/c mice were induced by imiquimod to create psoriasis-like mice model. Different doses of Yinxieling were administered to the psoriasis-like mice and PASI scores, thickness of epidermis and Keratin 17 expression of psoriasis-like mice were measured. In vitro, Ha- CaT cells were induced by IL-17A, IL-22 and TNF-alpha to establish psoriasis-like cells model. Yinxieling with different concentrations was administered to the psoriasis-like cells and Keratin 17 expression, adenosine triphosphate levels, and oxygen consumption rates were measured. Furthermore, the psoriasis-like cells were transfected with keratin 17 plasmids. Yinxieling intervened in these psoriasis-like cells with continuous high expression of keratin 17 and adenosine triphosphate levels and oxygen consumption rates were measured. Results: Yinxieling significantly improved PASI scores and decreased their epidermal thickness in psoriasis-like mice; Yinxieling also inhibited Krt17 expression in psoriasis-like mice and cells. Yinxieling improved ATP levels and oxygen consumption rate in psoriasis-like cells, and this effect of Yinxieling was abolished when the psoriasis-like cells were transfected with keratin 17 plasmids. Discussion: These findings suggest that Yinxieling alleviates psoriatic inflammation and improves mitochondrial function by downregulating KRT17. The study provides new mechanistic insights into the traditional use of Yinxieling and underscores the link between keratin dysregulation and mitochondrial impairment in psoriatic pathology. Conclusion: Yinxieling inhibits keratin 17 to enhance mitochondrial function and ameliorates psoriasis- like lesions.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147904770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Carrageenan on Pharmascience 卡拉胶对药物科学的影响
IF 0.6
Current Traditional Medicine Pub Date : 2024-01-11 DOI: 10.2174/0122150838266638231117180516
Akanksha Bhatt, Nidhi Nainwal, Priyank Purohit
{"title":"The Impact of Carrageenan on Pharmascience","authors":"Akanksha Bhatt, Nidhi Nainwal, Priyank Purohit","doi":"10.2174/0122150838266638231117180516","DOIUrl":"https://doi.org/10.2174/0122150838266638231117180516","url":null,"abstract":"\u0000\u0000Carrageenan (CG) a sulfated polysaccharide (SP) is produced using a variety of seaweeds from the Rhodophyceae family. This type of seaweed is available in areas, like the Atlantic Ocean close to Great Britain, Europe, and North America. Carrageenan has been permitted\u0000for the use as food items with the European additive E-number E407. Carrageenan is a widely\u0000used polysaccharide derived from red seaweed and is known for its various applications in the\u0000chemical, biological, and pharmaceutical fields. It delves into its versatile applications across\u0000various sub areas, spanning from the food to the pharmaceutical industry. A significant emphasis\u0000is placed on the intricate roles of carrageenan in pharmaceutical science, where it serves as both\u0000a drug carrier agent and an active ingredient, owing to its noteworthy biological activity. This\u0000review aims to provide a comprehensive overview of carrageenan`s versatile applications, with a\u0000focus on its chemical properties, biological activities, and pharmaceutical uses. The\u0000pharmaceutical applications of carrageenan are further categorized into various subparts,\u0000including its role in treating diseases and its use in drug delivery systems, such as topical, oral,\u0000nasal, and unconventional routes. The review also incorporates the most recent developments in\u0000clinical trials involving carrageenan and its updated applications, drawing from authoritative\u0000sources. This comprehensive analysis aims to offer readers a clear understanding of\u0000carrageenan's multifaceted nature and its evolving significance in diverse industries.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"12 9","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139438698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pro-oxidant Effects of Repeatedly Heated Sunflower Oil and the PossibleAmeliorative Potential of Elaeodendron transvaalense Leaf Powder inSprague Dawley Rats 反复加热的葵花籽油的促氧化作用和横叶桉叶粉对布拉格道利大鼠的可能改善潜力
IF 0.6
Current Traditional Medicine Pub Date : 2024-01-03 DOI: 10.2174/0122150838268705230928080148
T. Kwape, Kabo Masisi, Laone Kelaotswe, Keagile Bati, Phazha Baeti
{"title":"Pro-oxidant Effects of Repeatedly Heated Sunflower Oil and the Possible\u0000Ameliorative Potential of Elaeodendron transvaalense Leaf Powder in\u0000Sprague Dawley Rats","authors":"T. Kwape, Kabo Masisi, Laone Kelaotswe, Keagile Bati, Phazha Baeti","doi":"10.2174/0122150838268705230928080148","DOIUrl":"https://doi.org/10.2174/0122150838268705230928080148","url":null,"abstract":"\u0000\u0000Repeated heating of cooking oils induces the overproduction of reactive\u0000oxygen species with an overwhelmed cellular antioxidant defense system, resulting in oxidative\u0000stress, the known cause of cardiovascular diseases. Elaeodendron transvaalense is a medicinal\u0000plant believed to have phytochemicals that help ameliorate the effects of oxidative stress.\u0000\u0000\u0000\u0000This study investigated the pro-oxidant effects of repeatedly heated sunflower oil and\u0000the possible ameliorative potential of Elaeodendron transvaalense leaf powder in Sprague Dawley\u0000rats.\u0000\u0000\u0000\u0000Four groups of male Sprague Dawley rats were fed for 4-weeks a standard diet supplemented\u0000without (a) control or with (b) 15% (w/w) repeatedly heated sunflower oil (RHSO),\u0000(c) 15% (w/w) non-heated sunflower oil, (d) 15% (w/w) RHSO and 1.5% ETLP.\u0000\u0000\u0000\u0000Endogenous antioxidants: Catalase and SOD activities were observed to rise significantly\u0000(p <0.05) in Group 2 when compared to Group 1 and Group 3 respectively. A significant\u0000decline in the SOD and catalase activities was observed in group 4 fed RHSO + ETLP. No significant\u0000differences were observed in the body, liver, and kidney weights of Group 2 when compared\u0000with Groups 1, 3 and 4 respectively, and no significant differences were observed when\u0000comparing Group 4 to Groups 1, 2 and 3. The levels of Lipid profiles; Low-density Lipoproteins\u0000(LDL), Total cholesterol (TC), and Triglycerides (TG) were observed to rise significantly (p\u0000<0.05) in Group 2 when compared to Group 1 and 3, while their significant (p <0.05) decline\u0000was observed in Group 4 fed with RHSO + ETLP. The levels of HDL showed no significant difference\u0000across all groups because the p-values for the difference between groups exceeded the\u0000null hypothesis (p <0.05).\u0000\u0000\u0000\u0000The findings of this experiment indicate the possible ameliorative potential of\u0000ETLP observed in the significantly (p <0.05) reduced SOD and catalase activities. A significant\u0000(p <0.05) decline in the TC, TG, and LDL to desirable levels further indicated the ameliorative\u0000effects.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"89 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139388153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Euclea natalensis Suppresses Postprandial Hyperglycemia in Rats via theInhibition of α-Glucosidase: In vitro, in vivo, and Molecular Docking Studies Euclea natalensis 通过抑制α-葡萄糖苷酶抑制大鼠餐后高血糖:体外、体内和分子对接研究
IF 0.6
Current Traditional Medicine Pub Date : 2024-01-02 DOI: 10.2174/0122150838259363230922033947
Keagile Bati, R. Majinda, Goabaone Gaobotse, T. Kwape
{"title":"Euclea natalensis Suppresses Postprandial Hyperglycemia in Rats via the\u0000Inhibition of α-Glucosidase: In vitro, in vivo, and Molecular Docking Studies","authors":"Keagile Bati, R. Majinda, Goabaone Gaobotse, T. Kwape","doi":"10.2174/0122150838259363230922033947","DOIUrl":"https://doi.org/10.2174/0122150838259363230922033947","url":null,"abstract":"\u0000\u0000Postprandial hyperglycemia is a key factor in type 2 diabetes, and its\u0000management is critical in alleviating the deleterious consequences of diabetes and its associated\u0000micro and macrovascular complications.\u0000\u0000\u0000\u0000The current study aims to determine the effect of Euclea natalensis leaf extracts on α-\u0000glucosidase inhibition in vitro and postprandial hyperglycemia in vivo in rats.\u0000\u0000\u0000\u0000Sequentially extracted leaf extracts of Euclea natalensis were evaluated for their inhibitory\u0000effects on α-glucosidase in vitro and the suppression of postprandial hyperglycemia in\u0000normoglycemic rats. The extracts were fingerprinted using a Fourier-transform infrared spectrophotometer\u0000(FTIR), and the bioactive compounds were evaluated by molecular docking for their\u0000interaction with α-glucosidase.\u0000\u0000\u0000\u0000FTIR fingerprinting of the extracts showed that they contain functional groups of important\u0000bioactive phytochemicals. The extracts inhibited α-glucosidase in vitro, with the methanol\u0000extract (1 mg/mL) showing the highest inhibitory effect of 93.52 ± 1.50% compared to\u000069.62% ± 1.45 of the standard drug acarbose (0.05 mg/mL). The extracts also reduced postprandial\u0000hyperglycemia in rats in a sucrose tolerance test, where the hexane and methanol extracts\u0000performed similarly to Acarbose. Molecular docking studies showed that 20(29)-lupene-3β-\u0000isoferulate 3 is the most potent α-glucosidase inhibitor with the lowest binding energy of -10.79\u0000kcal/mol, 2 hydrogen bonds with residues ASP1526 and ASP1157, and numerous Van der Waal\u0000interactions with amino acids in the binding pocket of α-glucosidase.\u0000\u0000\u0000\u0000Euclea natalensis leaf extracts were found to suppress postprandial hyperglycemia\u0000by inhibiting α-glucosidase activity; thus, it has a promising potential for use as an antidiabetic\u0000agent.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"26 10","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139452228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation and Standardisation of Ayurvedic Lepa - A Traditional LepaChikitsa Therapy: An Ayurveda Cosmetology from Traditional to ModernPerspective 阿育吠陀 Lepa(一种传统的 LepaChikitsa 疗法)的评估和标准化:从传统到现代的阿育吠陀美容学
IF 0.6
Current Traditional Medicine Pub Date : 2023-12-11 DOI: 10.2174/0122150838226522231113073535
Shuvendhu Gupta, A. Singh, Alok Sharma
{"title":"Evaluation and Standardisation of Ayurvedic Lepa - A Traditional Lepa\u0000Chikitsa Therapy: An Ayurveda Cosmetology from Traditional to Modern\u0000Perspective","authors":"Shuvendhu Gupta, A. Singh, Alok Sharma","doi":"10.2174/0122150838226522231113073535","DOIUrl":"https://doi.org/10.2174/0122150838226522231113073535","url":null,"abstract":"\u0000\u0000The skin is the largest and most important organ in the human body.\u0000Taking care of the skin is crucial for maintaining beauty and preventing skin issues.\u0000\u0000\u0000\u0000Recently, Ayurvedic Cosmetology has become very popular due to its availability,\u0000affordability, and long-lasting benefits. Simple formulations like herbal pastes made from natural\u0000substances, peels, juices, and extracts are applied to the face. An ancient Ayurvedic text called\u0000\"The Sharangdhara Samhita\" provides detailed information about skin care, preventing skin disorders,\u0000and enhancing beauty. This text specifically focuses on \"The Lepa,\" which refers to topical\u0000applications for skincare and beauty. It mentions a total of 94 types of lepa, including 26 for\u0000treating skin disorders.\u0000\u0000\u0000\u0000The present work is aimed to formulate four different lepa, which are mentioned\u0000in ancient text and standardization was carried out to confirm its identity and quality. Different\u0000parameters such as loss on drying, total ash, acid insoluble ash value, extraction, pH, and\u0000solubility were performed.\u0000\u0000\u0000\u0000This work highlights a neglected section of Ayurveda that has the potential for future\u0000advancements in skincare and more phytochemical studies are required for the lead identification\u0000of lead molecule.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"7 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138980162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vyadhi-Kshamatava: An Immunotherapeutic Concept in Ayurveda Vyadhi-Kshamatava:阿育吠陀中的免疫治疗概念
IF 0.6
Current Traditional Medicine Pub Date : 2023-12-11 DOI: 10.2174/0122150838211267231113074710
Rashmi Singh, Alok Sharma
{"title":"Vyadhi-Kshamatava: An Immunotherapeutic Concept in Ayurveda","authors":"Rashmi Singh, Alok Sharma","doi":"10.2174/0122150838211267231113074710","DOIUrl":"https://doi.org/10.2174/0122150838211267231113074710","url":null,"abstract":"\u0000\u0000Ayurveda mainly focuses on treating diseases which aims at disease prevention. According\u0000to ayurveda, a disease is caused by inappropriate intellect, constitution, moral conduct,\u0000karma, and inappropriate contact with sensory perceptions such as sound, touch, vision, taste,\u0000and smell. These factors influence how diseases present themselves, whether they are mild, severe,\u0000acute, chronic, easily treatable, or incurable. The concept of \"Vyadhikshamatva\" in Ayurveda\u0000represents the fundamental principles of immunity. Ayurveda uses the terms \"Vyadhi\" and\u0000\"Kshamatva\" to describe illness and adaptation, respectively. According to Ayurveda, an imbalance\u0000in the Doshas leads to the development of diseases. In Ayurveda, immunity is referred to as\u0000\"Vyadhikshamatva\" and according to ayurvedic biology, Vyadhikshamatva can be correlated\u0000with the concept of immunity. Sahaja bala, Kalaja and yuktikrita bala refer to innate immunity\u0000and acquired immunity. The current work is focused on the concept of immunity in ayurveda.\u0000Various literatures have been collected from various sources such as ancient textbooks and references\u0000to highlight ayurvedic immunity concept and the management of disease by executing different\u0000ayurvedic principles. The result highlights the concept of Vyadhikshamatva as mentioned\u0000in Ayurvedic text which is considered Immunity. Therefore, the present work could contribute to\u0000ayurvedic biology and explore the concept of Vyadhikshamatva with the immunity in future.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"18 6","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138978765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunity Boosting Herbs For Fighting COVID-19 抗击 COVID-19 的增强免疫力草药
IF 0.6
Current Traditional Medicine Pub Date : 2023-11-24 DOI: 10.2174/0122150838237067231010041602
Prerna Sharma, N. Rani, Vikas Sharma, Nitin Goel, Sanchit Dhankhar
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