Ethnopharmacological Insights on Therapeutic Potential of Oleanolic Acid: A Review

Introduction: Plants have long been utilised as a supplement or alternative treatment for chronic conditions due to their therapeutic capabilities. Objectives: The objective of this study is to explore the ethnopharmacological aspects and therapeutic potential of naturally occurring oleanolic acid. Method: Information regarding oleanolic acid was collected from electronic databases, such as ScienceDirect, Web of Science, PubMed, Springer, Journal websites, Google Scholar, Taylor and Francis, Scopus and Wiley Online Library. Result: The article covered a wide range of immunomodulatory, antihypertensive, anticancer, antiinflammatory, antianxiety, antidepressant, antiischemic, antiviral, and other effects of triterpenoids. One such triterpenoid is oleanolic acid, which was reported to be present in a number of plants with a wide range of pharmacological potential. This article discussed the promising possibilities for alternative neurodegenerative disease treatment and management through oleanolic acid and its derivatives. Conclusion: The goal of this systematic review was to review the medicinal importance of oleanolic acid, extracted from a variety of plants used as a dietary source, such as apple, pomegranate, lemon, grapes, pears, olive, a highly powerful molecule with a wide range of biological actions, such as anti-microbial, anti-viral, anti-diabetic, hepatoprotective, antihypertensive, antiinflammatory, anticancer, anti-ischemic, antiviral, and cytotoxic properties.