ACS Central Science最新文献_第7页

Plastic Pores for Switchable and Optimized Adsorption Behaviors 可切换和优化吸附行为的塑料孔

IF 12.7 1区化学

ACS Central Science Pub Date : 2025-03-13 DOI: 10.1021/acscentsci.4c0215510.1021/acscentsci.4c02155

Xue-Wen Zhang, Rong-Hua Wang, Jie-Peng Zhang* and Xiao-Ming Chen,

{"title":"Plastic Pores for Switchable and Optimized Adsorption Behaviors","authors":"Xue-Wen Zhang, Rong-Hua Wang, Jie-Peng Zhang* and Xiao-Ming Chen, ","doi":"10.1021/acscentsci.4c0215510.1021/acscentsci.4c02155","DOIUrl":"https://doi.org/10.1021/acscentsci.4c02155https://doi.org/10.1021/acscentsci.4c02155","url":null,"abstract":"Similar to conventional solids, porous materials have demonstrated rigid and flexible behaviors. Here, we show that flexible pores can be not just elastic but also plastic. By variation of the hydrogen-bonding ability and steric hindrance of ligand side groups, the energy difference and barrier between metastable states of a porous framework are fine-tuned to enable the plastic behavior. All metastable pore structures can transform to the target ones in atmospheres of the target guests with sufficiently high pressures, and all shaped pores can remain unchanged after guest removal, resulting in optimized host–guest recognitions for the target guests. Up to a 6-fold increase of adsorption selectivity and 9-fold increase of purification productivity for CO2 capture and coalmine CH4 upgrading, and even inversion of CO2/C2H2 selectivity, have been achieved by reversible pore-shaping of a single plastic-pore adsorbent. The realization of plastic pores creates an opportunity for on-demand switching of adsorption and separation functions with optimized performances.While porous materials possess rigid or flexible/elastic pores, a plastic pore is realized for the first time, which can be shaped by target guest molecules to meet needs of different applications.","PeriodicalId":10,"journal":{"name":"ACS Central Science","volume":"11 3","pages":"479–485 479–485"},"PeriodicalIF":12.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acscentsci.4c02155","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143696536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Spin-Phonon Relaxation Mechanism of Single-Molecule Magnets in the Presence of Strong Exchange Coupling 强交换耦合存在下单分子磁体的自旋声子弛豫机制

IF 12.7 1区化学

ACS Central Science Pub Date : 2025-03-13 DOI: 10.1021/acscentsci.4c0213910.1021/acscentsci.4c02139

Sourav Mondal, Julia Netz, David Hunger, Simon Suhr, Biprajit Sarkar, Joris van Slageren, Andreas Köhn and Alessandro Lunghi*,

{"title":"The Spin-Phonon Relaxation Mechanism of Single-Molecule Magnets in the Presence of Strong Exchange Coupling","authors":"Sourav Mondal, Julia Netz, David Hunger, Simon Suhr, Biprajit Sarkar, Joris van Slageren, Andreas Köhn and Alessandro Lunghi*, ","doi":"10.1021/acscentsci.4c0213910.1021/acscentsci.4c02139","DOIUrl":"https://doi.org/10.1021/acscentsci.4c02139https://doi.org/10.1021/acscentsci.4c02139","url":null,"abstract":"Magnetic relaxation in coordination compounds is largely dominated by the interaction of the spin with phonons. Although a comprehensive understanding of spin-phonon relaxation has been achieved for mononuclear complexes, only a qualitative picture is available for polynuclear compounds. Large zero-field splitting and exchange coupling values have been empirically found to strongly suppress spin relaxation and have been used as the main guideline for designing molecular compounds with long spin lifetime, also known as single-molecule magnets, but no microscopic rationale for these observations is available. Here we fill this critical knowledge gap by providing a full first-principles description of spin-phonon relaxation in an air-stable Co(II) dimer with both large single-ion anisotropy and exchange coupling. Simulations reproduce the experimental relaxation data with excellent accuracy and provide a microscopic understanding of Orbach and Raman relaxation pathways and their dependency on exchange coupling, zero-field splitting, and molecular vibrations. Theory and numerical simulations show that increasing cluster nuclearity to just four cobalt units would lead to a complete suppression of low-temperature Raman relaxation. These results hold a general validity for polynuclear single-molecule magnets, providing a deeper understanding of their relaxation and revised strategies for their improvement.Spin relaxation in polynuclear coordination complexes is unraveled through ab initio open quantum system simulations, revealing new strategies to fully suppress Raman relaxation at low temperature.","PeriodicalId":10,"journal":{"name":"ACS Central Science","volume":"11 4","pages":"550–559 550–559"},"PeriodicalIF":12.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acscentsci.4c02139","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polyacrylamide-Based Antimicrobial Copolymers to Replace or Rescue Antibiotics. 基于聚丙烯酰胺的抗菌共聚物取代或挽救抗生素。

IF 12.7 1区化学

ACS Central Science Pub Date : 2025-03-13 eCollection Date: 2025-03-26 DOI: 10.1021/acscentsci.4c01973

Shoshana C Williams, Madeline B Chosy, Carolyn K Jons, Changxin Dong, Alexander N Prossnitz, Xinyu Liu, Hector Lopez Hernandez, Lynette Cegelski, Eric A Appel

{"title":"Polyacrylamide-Based Antimicrobial Copolymers to Replace or Rescue Antibiotics.","authors":"Shoshana C Williams, Madeline B Chosy, Carolyn K Jons, Changxin Dong, Alexander N Prossnitz, Xinyu Liu, Hector Lopez Hernandez, Lynette Cegelski, Eric A Appel","doi":"10.1021/acscentsci.4c01973","DOIUrl":"10.1021/acscentsci.4c01973","url":null,"abstract":"Antibiotics save countless lives each year and have dramatically improved human health outcomes since their introduction in the 20th century. Unfortunately, bacteria are now developing resistance to antibiotics at an alarming rate, with many new strains of \"superbugs\" showing simultaneous resistance to multiple classes of antibiotics. To mitigate the global burden of antimicrobial resistance, we must develop new antibiotics that are broadly effective, safe, and highly stable to enable global access. In this manuscript, we report the development of polyacrylamide-based copolymers as a class of broad-spectrum antibiotics with efficacy against several critical pathogens. We demonstrate that these copolymer drugs are selective for bacteria over mammalian cells, indicating a favorable safety profile. We show that they kill bacteria through a membrane disruption mechanism, which allows them to overcome traditional mechanisms of antimicrobial resistance. Finally, we demonstrate their ability to rehabilitate an existing small-molecule antibiotic that is highly subject to resistance development by improving its potency and eliminating the development of resistance in a combination treatment. This work represents a significant step toward combating antimicrobial resistance.","PeriodicalId":10,"journal":{"name":"ACS Central Science","volume":"11 3","pages":"486-496"},"PeriodicalIF":12.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Spin-Phonon Relaxation Mechanism of Single-Molecule Magnets in the Presence of Strong Exchange Coupling. 强交换耦合存在下单分子磁体的自旋声子弛豫机制。

IF 12.7 1区化学

ACS Central Science Pub Date : 2025-03-13 eCollection Date: 2025-04-23 DOI: 10.1021/acscentsci.4c02139

Sourav Mondal, Julia Netz, David Hunger, Simon Suhr, Biprajit Sarkar, Joris van Slageren, Andreas Köhn, Alessandro Lunghi

{"title":"The Spin-Phonon Relaxation Mechanism of Single-Molecule Magnets in the Presence of Strong Exchange Coupling.","authors":"Sourav Mondal, Julia Netz, David Hunger, Simon Suhr, Biprajit Sarkar, Joris van Slageren, Andreas Köhn, Alessandro Lunghi","doi":"10.1021/acscentsci.4c02139","DOIUrl":"https://doi.org/10.1021/acscentsci.4c02139","url":null,"abstract":"Magnetic relaxation in coordination compounds is largely dominated by the interaction of the spin with phonons. Although a comprehensive understanding of spin-phonon relaxation has been achieved for mononuclear complexes, only a qualitative picture is available for polynuclear compounds. Large zero-field splitting and exchange coupling values have been empirically found to strongly suppress spin relaxation and have been used as the main guideline for designing molecular compounds with long spin lifetime, also known as single-molecule magnets, but no microscopic rationale for these observations is available. Here we fill this critical knowledge gap by providing a full first-principles description of spin-phonon relaxation in an air-stable Co(II) dimer with both large single-ion anisotropy and exchange coupling. Simulations reproduce the experimental relaxation data with excellent accuracy and provide a microscopic understanding of Orbach and Raman relaxation pathways and their dependency on exchange coupling, zero-field splitting, and molecular vibrations. Theory and numerical simulations show that increasing cluster nuclearity to just four cobalt units would lead to a complete suppression of low-temperature Raman relaxation. These results hold a general validity for polynuclear single-molecule magnets, providing a deeper understanding of their relaxation and revised strategies for their improvement.","PeriodicalId":10,"journal":{"name":"ACS Central Science","volume":"11 4","pages":"550-559"},"PeriodicalIF":12.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143950899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polyacrylamide-Based Antimicrobial Copolymers to Replace or Rescue Antibiotics 基于聚丙烯酰胺的抗菌共聚物取代或挽救抗生素

IF 12.7 1区化学

ACS Central Science Pub Date : 2025-03-13 DOI: 10.1021/acscentsci.4c0197310.1021/acscentsci.4c01973

Shoshana C. Williams, Madeline B. Chosy, Carolyn K. Jons, Changxin Dong, Alexander N. Prossnitz, Xinyu Liu, Hector Lopez Hernandez, Lynette Cegelski and Eric A. Appel*,

{"title":"Polyacrylamide-Based Antimicrobial Copolymers to Replace or Rescue Antibiotics","authors":"Shoshana C. Williams, Madeline B. Chosy, Carolyn K. Jons, Changxin Dong, Alexander N. Prossnitz, Xinyu Liu, Hector Lopez Hernandez, Lynette Cegelski and Eric A. Appel*, ","doi":"10.1021/acscentsci.4c0197310.1021/acscentsci.4c01973","DOIUrl":"https://doi.org/10.1021/acscentsci.4c01973https://doi.org/10.1021/acscentsci.4c01973","url":null,"abstract":"Antibiotics save countless lives each year and have dramatically improved human health outcomes since their introduction in the 20th century. Unfortunately, bacteria are now developing resistance to antibiotics at an alarming rate, with many new strains of “superbugs” showing simultaneous resistance to multiple classes of antibiotics. To mitigate the global burden of antimicrobial resistance, we must develop new antibiotics that are broadly effective, safe, and highly stable to enable global access. In this manuscript, we report the development of polyacrylamide-based copolymers as a class of broad-spectrum antibiotics with efficacy against several critical pathogens. We demonstrate that these copolymer drugs are selective for bacteria over mammalian cells, indicating a favorable safety profile. We show that they kill bacteria through a membrane disruption mechanism, which allows them to overcome traditional mechanisms of antimicrobial resistance. Finally, we demonstrate their ability to rehabilitate an existing small-molecule antibiotic that is highly subject to resistance development by improving its potency and eliminating the development of resistance in a combination treatment. This work represents a significant step toward combating antimicrobial resistance.Polyacrylamide-based copolymers function as broad-spectrum antibiotics via a membrane disruption mechanism. They can prevent or delay the onset of resistance and rehabilitate existing antibiotics.","PeriodicalId":10,"journal":{"name":"ACS Central Science","volume":"11 3","pages":"486–496 486–496"},"PeriodicalIF":12.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acscentsci.4c01973","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143696537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plastic Pores for Switchable and Optimized Adsorption Behaviors. 可切换和优化吸附行为的塑料孔。

IF 12.7 1区化学

ACS Central Science Pub Date : 2025-03-13 eCollection Date: 2025-03-26 DOI: 10.1021/acscentsci.4c02155

Xue-Wen Zhang, Rong-Hua Wang, Jie-Peng Zhang, Xiao-Ming Chen

{"title":"Plastic Pores for Switchable and Optimized Adsorption Behaviors.","authors":"Xue-Wen Zhang, Rong-Hua Wang, Jie-Peng Zhang, Xiao-Ming Chen","doi":"10.1021/acscentsci.4c02155","DOIUrl":"10.1021/acscentsci.4c02155","url":null,"abstract":"Similar to conventional solids, porous materials have demonstrated rigid and flexible behaviors. Here, we show that flexible pores can be not just elastic but also plastic. By variation of the hydrogen-bonding ability and steric hindrance of ligand side groups, the energy difference and barrier between metastable states of a porous framework are fine-tuned to enable the plastic behavior. All metastable pore structures can transform to the target ones in atmospheres of the target guests with sufficiently high pressures, and all shaped pores can remain unchanged after guest removal, resulting in optimized host-guest recognitions for the target guests. Up to a 6-fold increase of adsorption selectivity and 9-fold increase of purification productivity for CO2 capture and coalmine CH4 upgrading, and even inversion of CO2/C2H2 selectivity, have been achieved by reversible pore-shaping of a single plastic-pore adsorbent. The realization of plastic pores creates an opportunity for on-demand switching of adsorption and separation functions with optimized performances.","PeriodicalId":10,"journal":{"name":"ACS Central Science","volume":"11 3","pages":"479-485"},"PeriodicalIF":12.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modulating Neutrophil Extracellular Trap Formation In Vivo with Locoregional Precision Using Differently Charged Self-Assembled Hydrogels 利用不同电荷的自组装水凝胶调节中性粒细胞胞外陷阱在体内的局部精确形成

IF 12.7 1区化学

ACS Central Science Pub Date : 2025-03-12 DOI: 10.1021/acscentsci.4c0219810.1021/acscentsci.4c02198

Tania L. Lopez-Silva, Caleb F. Anderson and Joel P. Schneider*,

{"title":"Modulating Neutrophil Extracellular Trap Formation In Vivo with Locoregional Precision Using Differently Charged Self-Assembled Hydrogels","authors":"Tania L. Lopez-Silva, Caleb F. Anderson and Joel P. Schneider*, ","doi":"10.1021/acscentsci.4c0219810.1021/acscentsci.4c02198","DOIUrl":"https://doi.org/10.1021/acscentsci.4c02198https://doi.org/10.1021/acscentsci.4c02198","url":null,"abstract":"Neutrophil extracellular traps (NETs) are DNA networks released by neutrophils, first described as a defense response against pathogens but have since been associated with numerous inflammatory diseases. Diverse physical material properties have been shown to promote NET formation. Herein, we report the discovery that the charge of self-assembled peptide hydrogels predictably modulates the formation of NETs in vivo within the implanted material. Positively charged gels induce rapid NET release, whereas negatively charged gels do not. This differential immune response to our self-assembled peptide gels enabled the development of a material platform that allows rheostat-like modulation over the degree of NET formation with anatomical and locoregional control.Self-assembled peptide-based hydrogel strategy for controlling the formation of neutrophil extracellular traps (NETs) in vivo with anatomical and locoregional precision, and the ability to regulate the degree of the response.","PeriodicalId":10,"journal":{"name":"ACS Central Science","volume":"11 3","pages":"465–478 465–478"},"PeriodicalIF":12.7,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acscentsci.4c02198","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143696295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modulating Neutrophil Extracellular Trap Formation In Vivo with Locoregional Precision Using Differently Charged Self-Assembled Hydrogels. 利用不同电荷的自组装水凝胶调节中性粒细胞胞外陷阱在体内的局部精确形成。

IF 12.7 1区化学

ACS Central Science Pub Date : 2025-03-12 eCollection Date: 2025-03-26 DOI: 10.1021/acscentsci.4c02198

Tania L Lopez-Silva, Caleb F Anderson, Joel P Schneider

引用次数: 0

Challenging Reaction Prediction Models to Generalize to Novel Chemistry. 具有挑战性的反应预测模型推广到新的化学。

IF 12.7 1区化学

ACS Central Science Pub Date : 2025-03-12 eCollection Date: 2025-04-23 DOI: 10.1021/acscentsci.5c00055

John Bradshaw, Anji Zhang, Babak Mahjour, David E Graff, Marwin H S Segler, Connor W Coley

{"title":"Challenging Reaction Prediction Models to Generalize to Novel Chemistry.","authors":"John Bradshaw, Anji Zhang, Babak Mahjour, David E Graff, Marwin H S Segler, Connor W Coley","doi":"10.1021/acscentsci.5c00055","DOIUrl":"https://doi.org/10.1021/acscentsci.5c00055","url":null,"abstract":"Deep learning models for anticipating the products of organic reactions have found many use cases, including validating retrosynthetic pathways and constraining synthesis-based molecular design tools. Despite compelling performance on popular benchmark tasks, strange and erroneous predictions sometimes ensue when using these models in practice. The core issue is that common benchmarks test models in an in-distribution setting, whereas many real-world uses for these models are in out-of-distribution settings and require a greater degree of extrapolation. To better understand how current reaction predictors work in out-of-distribution domains, we report a series of more challenging evaluations of a prototypical SMILES-based deep learning model. First, we illustrate how performance on randomly sampled data sets is overly optimistic compared to performance when generalizing to new patents or new authors. Second, we conduct time splits that evaluate how models perform when tested on reactions published years after those in their training set, mimicking real-world deployment. Finally, we consider extrapolation across reaction classes to reflect what would be required for the discovery of novel reaction types. This panel of tasks can reveal the capabilities and limitations of today's reaction predictors, acting as a crucial first step in the development of tomorrow's next-generation models capable of reaction discovery.","PeriodicalId":10,"journal":{"name":"ACS Central Science","volume":"11 4","pages":"539-549"},"PeriodicalIF":12.7,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143950902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenging Reaction Prediction Models to Generalize to Novel Chemistry 具有挑战性的反应预测模型推广到新的化学

IF 12.7 1区化学

ACS Central Science Pub Date : 2025-03-12 DOI: 10.1021/acscentsci.5c0005510.1021/acscentsci.5c00055

John Bradshaw, Anji Zhang, Babak Mahjour, David E. Graff, Marwin H. S. Segler and Connor W. Coley*,

{"title":"Challenging Reaction Prediction Models to Generalize to Novel Chemistry","authors":"John Bradshaw, Anji Zhang, Babak Mahjour, David E. Graff, Marwin H. S. Segler and Connor W. Coley*, ","doi":"10.1021/acscentsci.5c0005510.1021/acscentsci.5c00055","DOIUrl":"https://doi.org/10.1021/acscentsci.5c00055https://doi.org/10.1021/acscentsci.5c00055","url":null,"abstract":"Deep learning models for anticipating the products of organic reactions have found many use cases, including validating retrosynthetic pathways and constraining synthesis-based molecular design tools. Despite compelling performance on popular benchmark tasks, strange and erroneous predictions sometimes ensue when using these models in practice. The core issue is that common benchmarks test models in an in-distribution setting, whereas many real-world uses for these models are in out-of-distribution settings and require a greater degree of extrapolation. To better understand how current reaction predictors work in out-of-distribution domains, we report a series of more challenging evaluations of a prototypical SMILES-based deep learning model. First, we illustrate how performance on randomly sampled data sets is overly optimistic compared to performance when generalizing to new patents or new authors. Second, we conduct time splits that evaluate how models perform when tested on reactions published years after those in their training set, mimicking real-world deployment. Finally, we consider extrapolation across reaction classes to reflect what would be required for the discovery of novel reaction types. This panel of tasks can reveal the capabilities and limitations of today’s reaction predictors, acting as a crucial first step in the development of tomorrow’s next-generation models capable of reaction discovery.Despite excellent benchmark performance, ML models for reaction prediction can struggle on real-world data─we evaluate these limitations by challenging a model on different out-of-distribution tasks.","PeriodicalId":10,"journal":{"name":"ACS Central Science","volume":"11 4","pages":"539–549 539–549"},"PeriodicalIF":12.7,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acscentsci.5c00055","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0