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Did the United States smokeless tobacco industry use cigarette industry strategies to sponsor and manipulate research? 美国无烟烟草行业是否利用卷烟行业的策略来赞助和操纵研究?
IF 5.2 1区 医学
Addiction Pub Date : 2025-03-15 DOI: 10.1111/add.70039
David S Timberlake, Bryan D Nguyen, Andrew T Nguyen
{"title":"Did the United States smokeless tobacco industry use cigarette industry strategies to sponsor and manipulate research?","authors":"David S Timberlake, Bryan D Nguyen, Andrew T Nguyen","doi":"10.1111/add.70039","DOIUrl":"https://doi.org/10.1111/add.70039","url":null,"abstract":"<p><strong>Background and aim: </strong>The cigarette industry in the United States (US) laid the foundation for sponsoring research to improve public relations and defend against product liability cases. Fewer threats of litigation facing the US smokeless tobacco (SLT) industry may have contributed to the sponsorship of independent research on SLT use and health outcomes. This study aimed to determine whether the SLT industry used cigarette industry strategies to manipulate research on health risks.</p><p><strong>Methods: </strong>Internal industry documents (e.g. letters, memos) from the 1970s through 1990s were accessed through the online Truth Tobacco Industry Documents Library at the University of California, San Francisco. A framework of tobacco industry strategies and criteria for evaluating sponsored research formed the basis for categorizing and synthesizing documents identified via snowball sampling (n = 177). Summaries of awarded projects in annual reports of the Smokeless Tobacco Research Council (STRC) were coded for content (n = 189, 1982-1997).</p><p><strong>Results: </strong>Guided by legal counsel, the SLT industry sponsored research to support its interest group position; advocated against research on tobacco-specific carcinogens such as N-nitrosonornicotine (NNN); heavily criticized a case-control study on oropharyngeal cancer; and relied on a cadre of grantees and STRC leadership to testify against SLT restrictions. The STRC awarded a high proportion of projects on nicotine (78/189), including use for therapy (e.g. Tourette's syndrome), but underfunded epidemiologic research (n = 3). However, the STRC awarded projects on extracts or constituents (e.g. NNN, n = 30) that may have implicated SLT's role in carcinogenesis.</p><p><strong>Conclusions: </strong>While the Smokeless Tobacco Research Council awarded some research that may have weakened the industry, the Council's imbalanced portfolio of projects and inextricable link to industry likely favored the interest group position. Thus, we cannot conclude that the smokeless tobacco industry sponsored research solely for scientific discovery. Greater independence of industry-sponsored research could be achieved by delegating scientific decision-making to scientists (not legal counsel), limiting governance to those unaffiliated with the industry sponsor and not relying on grantees to defend the interest group position.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amphetamine use and mental health difficulties across adolescence and young adulthood: An integrative data analysis of four Australasian cohort studies. 安非他明的使用与青春期和青年期的心理健康问题:四项澳大利亚队列研究的综合数据分析。
IF 5.2 1区 医学
Addiction Pub Date : 2025-03-15 DOI: 10.1111/add.70033
Christopher J Greenwood, James Foulds, Rebecca McKetin, Stephanie R Aarsman, Delyse Hutchinson, Jessica Kerr, Jessica A Heerde, John W Toumbourou, Joseph M Boden, Tim Slade, Yvonne Bonomo, Primrose Letcher, Craig A Olsson
{"title":"Amphetamine use and mental health difficulties across adolescence and young adulthood: An integrative data analysis of four Australasian cohort studies.","authors":"Christopher J Greenwood, James Foulds, Rebecca McKetin, Stephanie R Aarsman, Delyse Hutchinson, Jessica Kerr, Jessica A Heerde, John W Toumbourou, Joseph M Boden, Tim Slade, Yvonne Bonomo, Primrose Letcher, Craig A Olsson","doi":"10.1111/add.70033","DOIUrl":"https://doi.org/10.1111/add.70033","url":null,"abstract":"<p><strong>Background and aims: </strong>The use of amphetamines (including amphetamine and methamphetamine) has been consistently associated with mental health difficulties; however, the direction of potential causal relationships has not yet been established. This study aimed to assess the direction relationships between illicit amphetamine use and mental health difficulties across adolescence and young adulthood.</p><p><strong>Design: </strong>Observational study of four population-level cohorts participating in the Monitoring Illicit Substance Use (MISUse) Consortium.</p><p><strong>Setting: </strong>Australia and New Zealand.</p><p><strong>Participants: </strong>A total of 7527 participants (51% female) were used: Christchurch Health and Development Study (n = 1056), Australian Temperament Project (n = 1644), Victorian Adolescent Health Cohort Study (n = 1943) and International Youth Development Study (n = 2884).</p><p><strong>Measurements: </strong>Assessments were used to derive binary indicators of amphetamine use (≥monthly) and mental health difficulties during both adolescence (age 10-17 years) and young adulthood (age 18-30 years).</p><p><strong>Findings: </strong>Associations were estimated as Risk Ratios (RRs) with 95% confidence internals (CIs) using G-computation procedures, while accounting for 15 potential confounding factors and interactions between exposure and both study cohort and participant sex. The risk of mental health difficulties in young adulthood was 21% greater (RR = 1.21, 95% CI = 1.04, 1.41) for those who reported monthly or more frequent amphetamine use in adolescence. The risk of monthly or higher amphetamine use in young adulthood was 19% greater (RR = 1.19, 95% CI = 0.99, 1.45) in those who reported mental health difficulties in adolescence. There was also some evidence to suggest that in males the strongest association was from amphetamine use to mental health difficulties (RR = 1.24, 95% CI = 0.95, 1.60), while in females the strongest association was from mental health difficulties to amphetamine use (RR = 1.33, 95% CI = 0.99, 1.78).</p><p><strong>Conclusions: </strong>There appears to be a bidirectional association between monthly or more frequent amphetamine use and mental health difficulties from adolescence to young adulthood.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Over a decade later and Addiction journal is still committed to publishing qualitative research. 十多年后,《成瘾》杂志仍然致力于发表定性研究。
IF 5.2 1区 医学
Addiction Pub Date : 2025-03-14 DOI: 10.1111/add.70047
Joanne Neale, Brian C Kelly, Jordan M Braciszewski, Joanna Kesten, Stephen Lankenau, Paula Mayock, Jennifer Merrill
{"title":"Over a decade later and Addiction journal is still committed to publishing qualitative research.","authors":"Joanne Neale, Brian C Kelly, Jordan M Braciszewski, Joanna Kesten, Stephen Lankenau, Paula Mayock, Jennifer Merrill","doi":"10.1111/add.70047","DOIUrl":"https://doi.org/10.1111/add.70047","url":null,"abstract":"","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decentering alcohol: Non-drug pleasure and reinforcement as an alternative target 去中心化酒精:非药物愉悦和强化作为替代目标。
IF 5.2 1区 医学
Addiction Pub Date : 2025-03-14 DOI: 10.1111/add.70048
Samuel F. Acuff, Justin C. Strickland
{"title":"Decentering alcohol: Non-drug pleasure and reinforcement as an alternative target","authors":"Samuel F. Acuff,&nbsp;Justin C. Strickland","doi":"10.1111/add.70048","DOIUrl":"10.1111/add.70048","url":null,"abstract":"&lt;p&gt;The opinion and debate piece by Nicholls and Hunt [&lt;span&gt;1&lt;/span&gt;] stimulates an interesting discussion on the importance of pleasure in public health-oriented research on alcohol. We agree that pleasure is an important concept in understanding alcohol use as well as other substance use, and that public health discourse limits its own efficacy by focusing primarily on harm without acknowledging many of the benefits people report experiencing from drinking (or other drug use). This idea is broadly consistent with the behavioral science literature, which posits that alcohol can function as a positive reinforcer by producing desirable effects (e.g. enhancing social connection, inducing pleasant subjective effects) that increase the likelihood of future alcohol use.&lt;/p&gt;&lt;p&gt;These reinforcing effects may, at least during any discrete use occasion, outweigh the costs, acute or chronic, of alcohol use [&lt;span&gt;2&lt;/span&gt;]. Although humans are motivated by costly immediate harms [&lt;span&gt;3&lt;/span&gt;], they are less so by delayed, diffuse, and uncertain ones [&lt;span&gt;4-6&lt;/span&gt;]. This human aversion to immediate harms is matched by an innate, evolutionarily adaptive drive for pleasure or related positive subjective states. From a population perspective, harms associated with alcohol use are characteristically delayed, diffuse and uncertain for most people who use alcohol, if they experience problems at all, and rewards are often immediate and robust. In the case of social connection, for example, alcohol may help to facilitate a basic human need of social bonding [&lt;span&gt;7, 8&lt;/span&gt;] while only inconsistently resulting in harms that lessen this potent reward. Ignoring the reality that many find alcohol to be pleasurable goes against the experience of many who drink and threatens to delegitimize public health messaging. A similar problem can be found in many treatment settings that focus almost exclusively on reiterating harms of alcohol while failing to acknowledge that drinking once served an adaptive function, even if for most it was maladaptive by the time treatment began.&lt;/p&gt;&lt;p&gt;Although perhaps conspicuously absent from public health messaging research, there is a rich history of experimental work describing the pleasurable effects of alcohol and other drugs [&lt;span&gt;9-12&lt;/span&gt;]. These studies, typically conducted in the framework described by the United States Food and Drug Administration Human Abuse Potential guidelines, seek to evaluate subjective effects like ‘Good Effect’ or ‘Drug Liking’ and determine the potential for a drug's future misuse [&lt;span&gt;13&lt;/span&gt;]. Notably, these studies highlight the role that pleasure, or more broadly positive reinforcing effects, play in determining future behavior—behaviors that evoke greater pleasure are more likely to be repeated in the future, and a drug's ‘abuse potential’ is at least in part related to its ability to induce pleasure.&lt;/p&gt;&lt;p&gt;In addition to understanding the importance of the reinforcing efficacy of alcoho","PeriodicalId":109,"journal":{"name":"Addiction","volume":"120 6","pages":"1086-1087"},"PeriodicalIF":5.2,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/add.70048","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Taking pleasure seriously: Should alcohol research say more about fun? ‘No safe level’ advocates must take note 认真对待快乐:酒精研究是否应该更多地说明快乐?“没有安全水平”的倡导者必须注意到这一点。
IF 5.2 1区 医学
Addiction Pub Date : 2025-03-14 DOI: 10.1111/add.70050
James Morris, Emma Davies
{"title":"Taking pleasure seriously: Should alcohol research say more about fun? ‘No safe level’ advocates must take note","authors":"James Morris,&nbsp;Emma Davies","doi":"10.1111/add.70050","DOIUrl":"10.1111/add.70050","url":null,"abstract":"&lt;p&gt;Nicholls and Hunt propose three arguments for why pleasure should be taken more seriously in alcohol research and policy debates [&lt;span&gt;1&lt;/span&gt;]. We concur with each, but focus here on the pragmatic case; namely, that ignoring the experienced pleasures of drinking can undermine public health efforts towards reducing alcohol harm.&lt;/p&gt;&lt;p&gt;Nicholls and Hunt highlight the limitations of health messages for behaviour change, notably observing that a public health ‘expert story’ of alcohol being inherently dangerous ‘runs hard against a public view of drinking’ as generally positive. We believe this is particularly important for public health actors to attend to, especially considering the increasing focus on cancer risks and ‘no safe level of consumption’ messaging. Psychological research has explored a range of phenomena that can inform public health messaging in this regard.&lt;/p&gt;&lt;p&gt;In addition to the risk of failing to change behaviour, messages that run against people's lived experiences risk backfire effects [&lt;span&gt;2&lt;/span&gt;]. Even neutral alcohol risk messages have been found to evoke &lt;i&gt;defensive processing&lt;/i&gt; amongst heavier drinkers, provoking denial, minimization or the avoidance of content, below conscious awareness [&lt;span&gt;3&lt;/span&gt;]. This resistance appears to increase linearly with the level of consumption, indicating that the more individually relevant the risk information, the more likely that drinkers are to reject it [&lt;span&gt;3&lt;/span&gt;]. This is not to infer that risk-based messaging is redundant; rather, the mixed evidence on its effectiveness highlights the need for further understanding of the specific role of message content and key moderating processes, such as perceived relevance, emotional responses and self-efficacy [&lt;span&gt;3-5&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Qualitative research has also identified how heavier drinkers use personal exceptionalism and othering as strategies to construct and place their own drinking as ‘responsible’ in contrast to a stereotyped ‘other’ [&lt;span&gt;6&lt;/span&gt;], including in response to alcohol health warnings [&lt;span&gt;7&lt;/span&gt;]. Drinkers perceive a wide range of positives associated with drinking and are skilled at deploying these to resolve any dissonance invoked by incongruent information [&lt;span&gt;6-8&lt;/span&gt;]. An evolving literature highlights how framing, stigma and identity processes may be involved in rejecting messages that are incongruent with a drinker's own experiences of alcohol use as being largely without problems and pleasurable [&lt;span&gt;3, 4, 9, 10&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;In addition to overlooking pleasure in drinking, ‘no safe level’ messaging may also reinforce the general perception that abstinence is the only acceptable goal. Indeed, abstinence can be perceived as threatening to drinkers and result in resistance or even the stigmatization of non-drinkers [&lt;span&gt;11&lt;/span&gt;]. Rather, it has been argued that an increasing recognition of moderation as an acceptable goal has a number of public health benefits [&lt;span&gt;12&lt;/span","PeriodicalId":109,"journal":{"name":"Addiction","volume":"120 6","pages":"1084-1085"},"PeriodicalIF":5.2,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/add.70050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medication experiences in the treatment of opioid use disorders: Insights from Reddit. 治疗阿片类药物使用障碍的药物经验:来自Reddit的见解。
IF 5.2 1区 医学
Addiction Pub Date : 2025-03-13 DOI: 10.1111/add.70022
Alexandra Almeida, Mike Conway, David J Grelotti, Amarnath Gupta, David Frank, Annick Bórquez
{"title":"Medication experiences in the treatment of opioid use disorders: Insights from Reddit.","authors":"Alexandra Almeida, Mike Conway, David J Grelotti, Amarnath Gupta, David Frank, Annick Bórquez","doi":"10.1111/add.70022","DOIUrl":"https://doi.org/10.1111/add.70022","url":null,"abstract":"<p><strong>Background and aims: </strong>Better understanding the challenges faced by patients on medications for opioid use disorder (MOUD), including methadone and buprenorphine, is critical to increasing their use/retention. Social media platforms such as Reddit offer a space for patients to share their experiences with medications. We aimed to identify and characterize challenges faced by patients taking MOUD through analysis of discussions from the r/Methadone and r/suboxone subreddits.</p><p><strong>Design, setting and participants: </strong>Mixed methods study applying natural language processing methods to 37 278 posts from both subreddits from their origin in 2011 until 31 December 2022. Independent topic analyses used Correlated Topic Models to extract the main themes discussed.</p><p><strong>Measurements: </strong>We labeled, validated and grouped the topics into macro classes and computed topic shares. We interpreted and compared topics across subreddits informed by the patient-centered medication experience framework.</p><p><strong>Findings: </strong>We found 27 and 34 challenge-related topics for the r/Methadone and r/suboxone subreddits, respectively. Topics were grouped into three macro-topics: (i) healthcare-related issues, including misunderstandings/confusion around appointments, prescriptions, bottle checks, telehealth technology and health insurance coverage; (ii) medication-related issues, including withdrawal, cravings, dosage, side effects, mixing with other medications/drugs; and (iii) treatment discontinuation, including tapering protocols. Patients conveyed highly specialized knowledge about dosage and tapering strategies and spoke from experience. Key differences between r/Methadone and r/suboxone were driven by their dispensing requirements (clinic-based vs. take-home), with 20.05% vs 14.74% of posts related to healthcare service, primarily for logistic and interpersonal issues with healthcare providers.</p><p><strong>Conclusion: </strong>People who post on the r/Methadone and r/suboxone subreddits appear to have detailed knowledge of medications for opioid use disorder and want more control over their dosing, effects, side effects and discontinuation. Acknowledging this expertise and establishing stronger patients' partnerships with the healthcare team and system might result in better treatment outcomes.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying hazardous alcohol use in primary care using phosphatidylethanol: Timing of screening matters. 使用磷脂酰乙醇识别初级保健中的有害酒精使用:筛选事项的时机。
IF 5.2 1区 医学
Addiction Pub Date : 2025-03-13 DOI: 10.1111/add.70036
Viktor Månsson, Maria Hårdstedt, Anders Hammarberg, Anders Hake, Riccardo LoMartire
{"title":"Identifying hazardous alcohol use in primary care using phosphatidylethanol: Timing of screening matters.","authors":"Viktor Månsson, Maria Hårdstedt, Anders Hammarberg, Anders Hake, Riccardo LoMartire","doi":"10.1111/add.70036","DOIUrl":"https://doi.org/10.1111/add.70036","url":null,"abstract":"<p><strong>Background and aims: </strong>Alcohol is a well-established risk factor for numerous health conditions, making screening for hazardous alcohol use in healthcare a critical task. While self-reported data suggest that alcohol consumption varies across seasons, this seasonal fluctuation has not yet been confirmed using objective biological markers. This study aimed to measure whether phosphatidylethanol (PEth) captures variations in hazardous alcohol use across two temporal resolutions: month of the year and day of the week.</p><p><strong>Design: </strong>Observational cross-sectional study based on data from medical records.</p><p><strong>Setting: </strong>Healthcare services, Region Dalarna, Sweden, between 2017 and 2023.</p><p><strong>Participants/cases: </strong>Adult patients (n = 62 431, 50% females) screened for hazardous alcohol use with PEth within primary care.</p><p><strong>Measurements: </strong>This study utilizes test results from PEth, with results >0.30 μmol/l defined as hazardous alcohol use. We compared the prevalence of hazardous alcohol use across months and weekdays using logistic regression while adjusting for sex, age, smoking status, the Charlson Comorbidity Index and psychiatric diagnoses.</p><p><strong>Findings: </strong>The prevalence of hazardous alcohol use increased between May and August, ranging from 13.2% to 15.9%, compared with 10.7% in November. This corresponds to a 48% relative increase in the peak month of July [prevalence ratio (PR) = 1.48, 95% confidence interval (CI) = 1.33-1.64]. Hazardous alcohol use was also more prevalent among patients tested on Mondays (13.0%) compared with Thursdays, with the lowest prevalence (12.0%). The difference was particularly pronounced among female patients, with a 14.0% higher relative prevalence on Mondays (PR = 1.14, 95% CI = 1.02-1.27).</p><p><strong>Conclusions: </strong>In Sweden, the prevalence of hazardous alcohol use appears to fluctuate seasonally and, to a lesser extent, across weekdays, as measured by blood tests for phosphatidylethanol, a biomarker for hazardous alcohol use. November showed the lowest prevalence and July the highest, consistent across age, sex and the year of the observational period. Hazardous alcohol use showed a slight elevation of prevalence during Mondays compared with Tuesday to Friday.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
intEgrating Smoking Cessation treatment As part of usual Psychological care for dEpression and anxiety (ESCAPE): A randomised and controlled, multi-centre, acceptability and feasibility trial with nested qualitative methods 将戒烟治疗作为抑郁和焦虑的常规心理护理的一部分(ESCAPE):一项随机对照、多中心、可接受性和可行性的嵌套定性方法试验。
IF 5.2 1区 医学
Addiction Pub Date : 2025-03-11 DOI: 10.1111/add.16718
Gemma M. J. Taylor, Katherine Sawyer, Pamela Jacobsen, Tom P. Freeman, Anna Blackwell, Shadi Daryan, Chris Metcalfe, David Kessler, Marcus R. Munafò, Paul Aveyard
{"title":"intEgrating Smoking Cessation treatment As part of usual Psychological care for dEpression and anxiety (ESCAPE): A randomised and controlled, multi-centre, acceptability and feasibility trial with nested qualitative methods","authors":"Gemma M. J. Taylor,&nbsp;Katherine Sawyer,&nbsp;Pamela Jacobsen,&nbsp;Tom P. Freeman,&nbsp;Anna Blackwell,&nbsp;Shadi Daryan,&nbsp;Chris Metcalfe,&nbsp;David Kessler,&nbsp;Marcus R. Munafò,&nbsp;Paul Aveyard","doi":"10.1111/add.16718","DOIUrl":"10.1111/add.16718","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background and aim&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;There is evidence that smoking cessation may improve depression and anxiety symptoms. We assessed the feasibility of implementing and trialling a smoking cessation intervention in services providing cognitive behavioural therapy (CBT) for common mental illness.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Design, setting and participants&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This study was a pragmatic, two-armed, randomised, multi-centre, acceptability and feasibility trial of a co-designed smoking cessation intervention (ISRCTN99531779) involving United Kingdom National Health Service (NHS)-funded services treating depression or anxiety among four NHS Trusts. Participants comprised adult daily smokers starting CBT for depression or anxiety [mean age 35.6 years, standard deviation (SD) = 12.7, 89.6% white] who smoked 14.3 (SD = 8.2) cigarettes/day with mean Generalised Anxiety Disorder Questionnaire-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9) scores of 13.1 (SD = 4.9) and 14.5 (SD = 6.0). Sixty-eight participants were allocated to the treatment group and 67 to control.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Intervention and control&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Both groups received CBT for depression or anxiety. The treatment group also received up to 12 sessions of integrated smoking cessation support. The control group was signposted to smoking cessation services post-treatment.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Measurements&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Follow-up was at 3 and 6 months. The primary outcome was ‘study completion’ by 3 months. Other outcomes included acceptability, satisfaction, feasibility, data completeness and mental health.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Findings&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;At 3 months, treatment did not affect study completion [odds ratio (OR) = 0.81, 95% confidence interval (CI) = 0.31 to 2.09], did not harm mental health (PHQ-9 difference: coefficient 0.01, 95% CI = −2.19 to 2.22); GAD-7: coefficient 0.65, 95% CI = −1.59 to 2.90), but increased abstinence rates (OR = 8.69, 95% CI = 1.11 to 396.26). Recruitment was acceptable and key stakeholders were satisfied with the intervention.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Among UK adult smokers receiving CBT treatment for depression or anxiety, a smoking cessation intervention within the CBT treatment was well received, did not interfere with the primary treatment goals and increased smoking cessation.&lt;/p&gt;\u0000 ","PeriodicalId":109,"journal":{"name":"Addiction","volume":"120 5","pages":"922-936"},"PeriodicalIF":5.2,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/add.16718","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Let's talk about pleasure: Bridging the sociology and public health divide 让我们谈谈快乐:弥合社会学和公共卫生的鸿沟。
IF 5.2 1区 医学
Addiction Pub Date : 2025-03-10 DOI: 10.1111/add.70035
Amy Pennay, Michael Livingston
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引用次数: 0
Commentary on Day et al.: From concept to practice-Challenges in building a continuum of recovery support services in Belgium. 对Day等人的评论:从概念到实践-在比利时建立连续的恢复支持服务的挑战。
IF 5.2 1区 医学
Addiction Pub Date : 2025-03-05 DOI: 10.1111/add.70020
Wouter Vanderplasschen, Florian De Meyer, Clara De Ruysscher
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引用次数: 0
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