Addiction最新文献

筛选
英文 中文
Commentary on Jackson et al.: The role of regional tobacco control in centralised nations. Jackson等人评论:中央集权国家区域烟草控制的作用。
IF 5.2 1区 医学
Addiction Pub Date : 2025-06-23 DOI: 10.1111/add.70112
Nathan Davies, Tessa Langley
{"title":"Commentary on Jackson et al.: The role of regional tobacco control in centralised nations.","authors":"Nathan Davies, Tessa Langley","doi":"10.1111/add.70112","DOIUrl":"https://doi.org/10.1111/add.70112","url":null,"abstract":"","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The lawsuit on tobacco point-of-sale displays in Hong Kong: An urgent call for the display ban. 香港烟草销售点陈列的诉讼:紧急呼吁禁止陈列。
IF 5.2 1区 医学
Addiction Pub Date : 2025-06-21 DOI: 10.1111/add.70113
Cara Hor Yine Cheung, Man Ping Wang, Yee Tak Derek Cheung
{"title":"The lawsuit on tobacco point-of-sale displays in Hong Kong: An urgent call for the display ban.","authors":"Cara Hor Yine Cheung, Man Ping Wang, Yee Tak Derek Cheung","doi":"10.1111/add.70113","DOIUrl":"10.1111/add.70113","url":null,"abstract":"","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trajectories of hospital-presenting alcohol-related disorders between early and late adulthood: Exploring the role of mortality in a prospective study of a 1953 cohort. 成年早期和晚期住院酒精相关疾病的发展轨迹:1953年一项前瞻性研究中死亡率的作用
IF 5.2 1区 医学
Addiction Pub Date : 2025-06-20 DOI: 10.1111/add.70107
Lauren Bishop, Lars Brännström, Ylva B Almquist
{"title":"Trajectories of hospital-presenting alcohol-related disorders between early and late adulthood: Exploring the role of mortality in a prospective study of a 1953 cohort.","authors":"Lauren Bishop, Lars Brännström, Ylva B Almquist","doi":"10.1111/add.70107","DOIUrl":"10.1111/add.70107","url":null,"abstract":"<p><strong>Background and aims: </strong>Alcohol-related disorders (ARDs) are associated with severe attributable harms that evolve throughout the life course, comprising distinct trajectories. Yet, how mortality affects the identification, shape and number of trajectory groups remains poorly understood. This study aimed to: (1) derive trajectories of hospital-presenting ARDs between early and late adulthood; (2) compare trajectories that include mortality information versus trajectories excluding individuals who died during follow-up; and (3) predict trajectory membership based on exposure to familial risk factors between ages 0-19.</p><p><strong>Design: </strong>Prospective cohort study using group-based trajectory modeling to identify hospital-presenting ARD trajectories.</p><p><strong>Setting: </strong>Stockholm, Sweden.</p><p><strong>Participants: </strong>1953 birth cohort (n = 14 608), with 43 years of follow-up data (ages 20-63), comprising two study samples: total sample (alive at age 20, n = 14 559) and surviving sample (alive at age 63, n = 13 276).</p><p><strong>Measurements: </strong>Hospital-presenting ARDs were measured using national inpatient care data (1973-2016). Familial risk factors were assessed using national and local records on parental alcohol-related offenses, mental health problems, criminality and investigations by child welfare services.</p><p><strong>Findings: </strong>Five distinct hospital-presenting ARD trajectories were identified in the total sample; four were identified in the surviving sample. Mortality disproportionately affected individuals assigned to the two trajectories characterized by medium-to-high peaks of hospital-presenting ARDs (64.9% and 80.6% attrition due to death, respectively). The most severe trajectory was not identified in the surviving sample. Familial risk factors were significant predictors of trajectory membership for both samples, with odds ratios ranging between 1.67 and 8.10, though with largely overlapping 95% confidence intervals between the two risk groups and across trajectories.</p><p><strong>Conclusions: </strong>Mortality may disproportionately affect individuals assigned to trajectories of hospital-presenting alcohol-related disorders (ARDs) characterized by severe alcohol-attributable harms. Longitudinal studies of ARDs that exclude deceased participants may therefore underrepresent the most vulnerable groups: those with chronic or escalating ARDs.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extended-release buprenorphine treatment for opioid use disorder: A mixed-methods study of response and experience. 丁丙诺啡缓释治疗阿片类药物使用障碍:反应和经验的混合方法研究。
IF 5.2 1区 医学
Addiction Pub Date : 2025-06-20 DOI: 10.1111/add.70106
Natalie Lowry, Andrew McKechnie, Edward Day, Eilish Gilvarry, Fiona Cowden, Rachel Evans, Rosie Locke, Robbie Murray, Rob Vanderwaal, Stacey Johnstone, Zoe Hoare, Michael Kelleher, Luke Mitcheson, John Marsden
{"title":"Extended-release buprenorphine treatment for opioid use disorder: A mixed-methods study of response and experience.","authors":"Natalie Lowry, Andrew McKechnie, Edward Day, Eilish Gilvarry, Fiona Cowden, Rachel Evans, Rosie Locke, Robbie Murray, Rob Vanderwaal, Stacey Johnstone, Zoe Hoare, Michael Kelleher, Luke Mitcheson, John Marsden","doi":"10.1111/add.70106","DOIUrl":"10.1111/add.70106","url":null,"abstract":"<p><strong>Background and aims: </strong>An investigation of 24 weeks of extended-release buprenorphine (BUP-XR; Sublocade®) treatment for adults with opioid use disorder (OUD). Study aims were to characterise variations in clinical response, investigate personal factors influencing BUP-XR experience and identify opportunities to tailor treatment interventions.</p><p><strong>Design: </strong>A convergent parallel mixed-methods evaluation embedded in a five-centre, phase 3, randomised controlled trial of BUP-XR versus daily oral methadone or sublingual buprenorphine.</p><p><strong>Setting: </strong>Four of five National Health Service addictions treatment clinics in England and Scotland from the trial.</p><p><strong>Participants: </strong>Participants were recruited after they completed the 24-week endpoint. Forty-nine participants (31%) from the trial completed the qualitative interview.</p><p><strong>Measurements: </strong>Three outcome measures from the trial's dataset were used descriptively: (1) fortnightly clinic visit administered TimeLine Follow-Back interview and urine drug screen data on use of non-medical opioids, cocaine and benzodiazepines; (2) the frequency version of the 11-item Craving Experience Questionnaire administered at baseline and endpoint; and (3) the Structured Clinical Interview for DSM-5 disorders for diagnosis of early OUD and cocaine use disorder (CUD) remission. Data visualisation (by heatmap) identified drug use response sub-groups. A topic-guided, semi-structured qualitative interview was analysed by Interactive Categorisation.</p><p><strong>Findings: </strong>Three response sub-groups were identified: Group 1 [14 (28.5%) of 49 participants] had the highest level of response, characterised by continuous abstinence from opioids, cocaine and benzodiazepines, improvements in craving control and mental and physical health in the majority, and a high level of remission and satisfaction with care; Group 2 [14 (28.5%) of 49 participants] had the next level of response, characterised by continuous abstinence from opioids, but some with opioid craving and some with compensatory use of cocaine and benzodiazepine to cope with anxiety and stress; Group 3 [21 (43.0%) of 49 participants] were not continuously abstinent from opioids during follow-up, the majority had dual OUD and CUD at trial enrolment, some reported breakthrough opioid withdrawal symptoms during follow-up, the majority reported improvements in mental health, but many reported opioid and cocaine cravings and compensatory use of cocaine and benzodiazepines.</p><p><strong>Conclusions: </strong>There appears to be variation in response and experience of extended-release buprenorphine during the first six months of treatment, depending on substance use and physical health. This highlights the need for tailored treatment plans based on differing individual needs.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimating recent trends in alcohol sales in the United Kingdom from alcohol duty revenue. 根据酒精税收入估计英国酒精销售的最新趋势。
IF 5.2 1区 医学
Addiction Pub Date : 2025-06-19 DOI: 10.1111/add.70109
Colin Angus, Jonas Schöley
{"title":"Estimating recent trends in alcohol sales in the United Kingdom from alcohol duty revenue.","authors":"Colin Angus, Jonas Schöley","doi":"10.1111/add.70109","DOIUrl":"https://doi.org/10.1111/add.70109","url":null,"abstract":"<p><strong>Background and aims: </strong>The onset of the COVID-19 pandemic led to significant changes in individual-level alcohol consumption and a sharp increase in heavy drinking in the United Kingdom (UK). More recently, high rates of inflation, the resulting 'cost of living crisis' and reforms to alcohol taxation have affected the affordability of alcohol, but little is understood about how these changes have impacted on alcohol sales and consumption. We aimed to measure recent trends in alcohol sales by assessing changes in alcohol duty revenue collected by the UK government since 2020.</p><p><strong>Methods: </strong>We used published data on UK alcohol duty revenue to model trends from 2010 to 2019. We forecasted these trends through to January 2025 using a novel statistical approach and compared these forecasts with observed receipts. Measurements included monthly inflation-adjusted alcohol duty receipts received by the UK Treasury in pounds sterling for beer, cider, spirits and wine.</p><p><strong>Results: </strong>During the pandemic, alcohol duty receipts fell during lockdowns and rose as restrictions were subsequently lifted. Since 2022 alcohol duty receipts have been consistently statistically significantly below the historical trend, with a cumulative deficit of £10.3bn (-12.3%). This has not been uniform across beverage types, with a gradually increasing deficit in wine receipts and a comparable deficit in spirits receipts that began sharply in late 2022 compared with smaller deficits for beer and cider. The reforms to the alcohol duty system in August 2023 do not appear to have substantially affected these trends.</p><p><strong>Conclusions: </strong>The 'cost of living crisis' in 2022/2023 appears to have been associated with a fall in alcohol sales in the United Kingdom relative to the pre-pandemic trend. The magnitude of this fall differs by beverage type, indicating that wine and spirits drinkers may have changed their behaviour more than beer and cider drinkers.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144323913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age-period-cohort analysis of past 12-month cannabis use in Germany (1995-2021). 德国过去12个月大麻使用的年龄期队列分析(1995-2021)。
IF 5.2 1区 医学
Addiction Pub Date : 2025-06-19 DOI: 10.1111/add.70087
Natalie S Schöllner, Adrian Glos, Justin Möckl, Eva-Maria Krowartz, Eva Hoch, Sally Olderbak
{"title":"Age-period-cohort analysis of past 12-month cannabis use in Germany (1995-2021).","authors":"Natalie S Schöllner, Adrian Glos, Justin Möckl, Eva-Maria Krowartz, Eva Hoch, Sally Olderbak","doi":"10.1111/add.70087","DOIUrl":"10.1111/add.70087","url":null,"abstract":"<p><strong>Background and aims: </strong>In 2024, cannabis was partially legalized for recreational purposes in Germany. With a growing prevalence of persons who used cannabis in the past 12 months, and the health risks associated with cannabis use, it is imperative to examine usage behavior patterns in greater detail. The present analysis measured the impact of age, time period and birth cohort on the prevalence of cannabis consumption in the past 12 months in Germany.</p><p><strong>Design: </strong>Longitudinal study using data from 10 waves (1995-2021) of the German Epidemiological Survey of Substance Abuse (ESA), a cross-sectional nationally representative household survey of individuals between the ages of 18 and 59 or 64 years.</p><p><strong>Setting: </strong>Germany.</p><p><strong>Participants: </strong>N<sub>total</sub> = 78 678 German-speaking adults between the ages of 18 and 59 years.</p><p><strong>Measurements: </strong>Self-report of cannabis use in the last 12 months as well as alcohol use and smoking conventional tobacco products in the last 30 days.</p><p><strong>Findings: </strong>We employed binary logistic regression using a generalized additive model to examine age, period and cohort effects, as well as covariate effects on past 12-month cannabis use. Over time, both period and cohort had an increasing effect, while an increase in age corresponded to a decrease in prevalence. Specifically, the odds ratio (OR) for cannabis use decreased from 9.44 [95% confidence interval (CI) = 8.17-10.9] at age 18 years to 0.13 (95 CI = 0.10-0.17) at age 59 years. Period effects also showed an increase, with the OR rising from 0.33 (95% CI = 0.26-0.43) in 1995 to 2.96 (95% CI = 2.55-3.43) in 2021, while cohort effects increased from 0.02 (95% CI = 0.001-0.05) for those born in 1936 to 16.69 (95% CI = 13.8-20.8) for those born in 2002. Additionally, persons using cannabis had a higher likelihood of also drinking alcohol and smoking conventional tobacco products in the last 30 days.</p><p><strong>Conclusions: </strong>In Germany, the odds of being a past-12-month cannabis consumer appears to decline with increasing age, indicating that only a small proportion of consumers engage in cannabis use throughout their whole lives, with a peak prevalence occurring at a younger age.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social cognition and decision-making in people with methamphetamine use disorder. 甲基苯丙胺使用障碍患者的社会认知与决策。
IF 5.2 1区 医学
Addiction Pub Date : 2025-06-16 DOI: 10.1111/add.70108
Justin Mahlberg, Lauren Hanegraaf, Josua Zimmermann, David M Cole, Boris B Quednow, Shalini Arunogiri, Antonio Verdejo-Garcia
{"title":"Social cognition and decision-making in people with methamphetamine use disorder.","authors":"Justin Mahlberg, Lauren Hanegraaf, Josua Zimmermann, David M Cole, Boris B Quednow, Shalini Arunogiri, Antonio Verdejo-Garcia","doi":"10.1111/add.70108","DOIUrl":"https://doi.org/10.1111/add.70108","url":null,"abstract":"<p><strong>Background and aims: </strong>Impairments in social cognition and social decision-making play an important role in the disease burden experienced by individuals with methamphetamine use disorder (MUD). They are also assumed to play a role in the vicious cycle of MUD development and hinder its successful psychotherapy. However, research typically focuses on examining specific types of social cognitive deficits in MUD, rather than profiling the multidimensional social cognition and decision-making impairments that coincide with MUD. Our study, thus, estimated the socio-cognitive and social decision-making profile of people with MUD and compared this profile with a methamphetamine-naïve control group.</p><p><strong>Design: </strong>Cross-sectional case-control comparison of social cognition and decision-making between participants with MUD recruited from clinical services and methamphetamine-naïve controls (CTRL) recruited from the community.</p><p><strong>Setting: </strong>Drug treatment clinics in Melbourne, Australia.</p><p><strong>Participants: </strong>52 participants with MUD (moderate or severe; 77% identified as male) between April 2019 and September 2021 and 51 demographically matched CTRLs (no history of methamphetamine use; 54% identified as male) between May and September of 2021.</p><p><strong>Measurements: </strong>We implemented a social cognition battery that assessed a participant's sensitivity for perceiving emotion from faces (emotion recognition) and their ability to detect accurately the emotional state of others (cognitive empathy) and experience the emotions of others (emotional empathy). We also characterised the propensity to engage in higher-order social decision-making by assessing a participant's willingness to engage in interpersonal trust and aggression in experimental simulations.</p><p><strong>Findings: </strong>Compared with matched controls, people with MUD had a bias toward perceiving happier facial expressions as neutral [Estimate = -5.05, standard error (SE) = 2.05, P = 0.016, 95% confidence interval (95% CI) = (-9.12 to -0.98)], showing lower sensitivity to perceiving happy emotions [Estimate = -6.34, SE = 3.09, P = 0.043, 95% CI = (-12.47 to -0.20)]. People with MUD also showed a propensity to enact more intense punishments [Estimate = 1.48, SE = 0.38, P < 0.001, 95% CI = (0.73-2.23)] and lower levels of trust to others in their decisions [Estimate = -0.11, SE = 0.04, P = 0.002, 95% CI = (-0.18 to -0.04)].</p><p><strong>Conclusions: </strong>In a clinical research study, people with methamphetamine use disorder appeared to show lower sensitivity to happy emotions, reduced trust and increased aggression toward others, relative to a matched control group.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations of plasma sex-related hormone and protein levels and alcohol dependence. 血浆性相关激素和蛋白质水平与酒精依赖的关系
IF 5.2 1区 医学
Addiction Pub Date : 2025-06-16 DOI: 10.1111/add.70104
Ada Man-Choi Ho, Jennifer R Geske, Vanessa K Pazdernik, T Cameron Waller, Anthony Batzler, Stacey J Winham, Victor M Karpyak
{"title":"Associations of plasma sex-related hormone and protein levels and alcohol dependence.","authors":"Ada Man-Choi Ho, Jennifer R Geske, Vanessa K Pazdernik, T Cameron Waller, Anthony Batzler, Stacey J Winham, Victor M Karpyak","doi":"10.1111/add.70104","DOIUrl":"https://doi.org/10.1111/add.70104","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background and aims: &lt;/strong&gt;Sex-related hormones and proteins may underlie sex differences in alcohol use disorder characteristics and consequences. Previous reports suggest steroid sex hormones may influence alcohol consumption behaviors while proteins that regulate their circulation levels are rarely investigated. Following up on our earlier study of individual sex-related hormones' associations with alcohol dependence (AD), this study measured the associations between the combinations of sex-related hormones and proteins and AD in a larger sample.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Design: &lt;/strong&gt;Sex-stratified case-control comparison and clustering of plasma sex-related hormone and protein levels, plus a genome-wide association study on the AD-associated hormone and protein combinations.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Setting: &lt;/strong&gt;Addiction treatment programs in the United States.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Participants: &lt;/strong&gt;Four hundred treatment-seeking recently abstained AD patients (median = 24.5 days) and 388 age-and-sex-matched controls from a community biobank (male:female ≈ 2:1).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Measurements: &lt;/strong&gt;Plasma levels of total testosterone, estrone (E1), estradiol (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH), sex hormone binding globulin (SHBG) and albumin.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Findings: &lt;/strong&gt;In males, we found higher E2 [β = 0.13, P&lt;sub&gt;unadjusted&lt;/sub&gt; &lt; 0.001, false discovery rate (FDR) = 0.005], progesterone (β = 0.01, P&lt;sub&gt;unadjusted&lt;/sub&gt; = 0.025, FDR = 0.054), LH (β = 0.12, P&lt;sub&gt;unadjusted&lt;/sub&gt; = 0.017, FDR = 0.044) and albumin (β = 0.09, P&lt;sub&gt;unadjusted&lt;/sub&gt; &lt; 0.001, FDR = 0.005) in AD patients than controls; in females, we observed lower E1 (β = -0.24, P&lt;sub&gt;unadjusted&lt;/sub&gt; = 0.024, FDR = 0.113) and progesterone (β = -1.86, P&lt;sub&gt;unadjusted&lt;/sub&gt; = 0.026, FDR = 0.113) and higher albumin (β = 0.18, P&lt;sub&gt;unadjusted&lt;/sub&gt; &lt; 0.001, FDR = 0.001) in AD patients than controls. Three principal components (PCs), reflecting hormone signatures, were statistically significantly associated with AD in each sex: PC1 (TT, E2 and SHBG; β = -0.15, P = 0.016), PC3 (E1, progesterone and albumin; β = 0.28, P = 0.007) and PC4 (SHBG and albumin; β = 0.34, P = 0.001) in males; PC3 (progesterone and albumin; β = -0.38, P = 0.009), PC4 (TT and albumin; β = -0.49, P = 0.001) and PC5 (TT and progesterone; β = 0.54, P = 0.004) in females. Statistically significant SNP × group associations were found in females between PC4 and polymorphisms in RP51004I9.1 (top SNP: rs6082693; P = 5.41E-12) and in males between PC3 and a genomic locus that contained SLC35E4, DUSP18 and OSBP2 (top SNP: rs13053277; P = 1.77E-07).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Three sex-related hormone and protein signatures appear to be associated with alcohol dependence in each sex. Peripheral levels of sex-related hormones and proteins, as well as their combinations, could be altered in people with alcohol dependence who have abstained for a few weeks compared with contro","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of acute psychosocial stress on cue-reactivity, attentional bias and implicit associations in women with problematic social network use: An experimental study. 急性社会心理应激对有问题社交网络使用女性的线索反应、注意偏差和内隐联想的影响:一项实验研究。
IF 5.2 1区 医学
Addiction Pub Date : 2025-06-13 DOI: 10.1111/add.70099
Annica Kessling, Astrid Müller, Oliver T Wolf, Christian J Merz, Matthias Brand, Elisa Wegmann
{"title":"Effects of acute psychosocial stress on cue-reactivity, attentional bias and implicit associations in women with problematic social network use: An experimental study.","authors":"Annica Kessling, Astrid Müller, Oliver T Wolf, Christian J Merz, Matthias Brand, Elisa Wegmann","doi":"10.1111/add.70099","DOIUrl":"https://doi.org/10.1111/add.70099","url":null,"abstract":"<p><strong>Background and aims: </strong>Situational triggers such as acute stress may exert significant effects on behavioral execution in addictive behaviors potentially leading to increased cue-reactivity and the expression of implicit cognitions. We measured the effects of acute stress on cue-reactivity, attentional bias and implicit associations to stimuli related to online social networks (SN) in problematic social network use (p-SNU) among women.</p><p><strong>Design, setting and participants: </strong>This was a mixed-method, cross-sectional, between-subjects design with 135 female participants recruited in Germany who were assigned to the group with p-SNU (n = 71) or the control group (n = 64) based on a diagnostic interview using DSM-5 criteria for gaming disorder (applied to p-SNU). Participants were randomly exposed to acute stress using the Trier Social Stress Test (TSST) or a placebo-TSST.</p><p><strong>Measurements: </strong>Participants performed a Cue-Reactivity Paradigm, Implicit Association Test and the Dot Probe Paradigm with SN-related stimuli.</p><p><strong>Findings: </strong>Acute stress led to increased subjective urge to use social networks in both groups [TSST: mean (M) = 2.26, standard deviation (SD) = 0.92, placebo-TSST: M = 2.08, SD = 0.96, F(1,131) = 6.820, P = 0.01, ηp<sup>2</sup> = 0.029]. In the placebo-TSST condition, the p-SNU group showed increased subjective arousal (p-SNU: M = 2.39, SD = 0.74; control group: M = 1.79, SD = 0.90, t<sub>70</sub> = 2.55, P = 0.013, │d│ = 0.30) and urge (p-SNU: M = 2.49, SD = 0.84; control group: M = 1.60, SD = 0.88, t<sub>70</sub> = 5.40,  P < 0.001, │d│ = 0.58) and the control group showed increased attentional bias (p-SNU: M = -1.75, SD = 16.11; control group: M = 6.43, SD = 15.3, t<sub>67</sub> = 2.136, P = 0.036, │d│ = 0.52). No group difference was found regarding the effects of acute stress on implicit associations to SN-related stimuli or an interaction effect of subjective urge and stress on implicit cognitions.</p><p><strong>Conclusions: </strong>Among women in Germany, acute stress appears to lead to an increased subjective urge for the use of social networks. Women with problematic social network use report higher subjective urge independent of stress, whereas women with non-problematic use report an attentional bias.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144281755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gambling website design as a factor in North American betting expansion. 赌博网站设计是北美博彩扩张的一个因素。
IF 5.2 1区 医学
Addiction Pub Date : 2025-06-09 DOI: 10.1111/add.70103
Luke Clark, Paul William Weston
{"title":"Gambling website design as a factor in North American betting expansion.","authors":"Luke Clark, Paul William Weston","doi":"10.1111/add.70103","DOIUrl":"https://doi.org/10.1111/add.70103","url":null,"abstract":"","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信