Addiction最新文献

{"title":"Commentary on Ezard et al.: Prescribed psychostimulant medications for methamphetamine use disorder - an urgent path forward.","authors":"Adam Bisaga","doi":"10.1111/add.70058","DOIUrl":"https://doi.org/10.1111/add.70058","url":null,"abstract":"","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic validity of drinking behaviour for identifying alcohol use disorder: Findings from a representative sample of community adults and an inpatient clinical sample.","authors":"Molly L Garber, Andriy Samokhvalov, Yelena Chorny, Onawa LaBelle, Brian Rush, Jean Costello, James MacKillop","doi":"10.1111/add.70037","DOIUrl":"https://doi.org/10.1111/add.70037","url":null,"abstract":"<p><strong>Background and aims: </strong>Alcohol consumption is an inherent feature of alcohol use disorder (AUD), and drinking patterns may be diagnostically informative. This study had three aims: (1) to examine the classification accuracy of several individually analysed drinking behavior measures in a large sample of US community adults; (2) to extend the findings to an adult clinical sample; and (3) to examine potential sex differences.</p><p><strong>Design: </strong>In cross-sectional epidemiological and clinical datasets, receiver operating characteristic (ROC) curves were used to evaluate diagnostic classification using area under the curve (AUC), accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV).</p><p><strong>Setting and participants: </strong>Two samples were examined: a large random sample of US community adults who reported past-year drinking (n = 25 773, AUD = 20%) and a clinical sample from a Canadian inpatient addiction treatment centre (n = 1341, AUD = 82%).</p><p><strong>Measurements: </strong>Classifiers included measures of quantity/frequency (e.g. drinks/drinking day, largest drinks/drinking day, number of drinking days and heavy drinking frequency). The clinical criterion (reference standard) was AUD diagnostic status per structured clinical interview (community sample) or a symptom checklist (clinical sample).</p><p><strong>Findings: </strong>All drinking indicators were statistically significant classifiers of AUD (AUCs = 0.60-0.92, Ps<0.0001). Heavy drinking frequency indicators performed optimally in both the community (AUCs = 0.78-0.87; accuracy = 0.72-0.80) and clinical (AUCs = 0.85-0.92; accuracy = 0.77-0.89) samples. Collectively, the most discriminating drinking behaviours were number of heavy drinking episodes and frequency of exceeding drinking low-risk guidelines. No substantive sex differences were observed across drinking metrics.</p><p><strong>Conclusions: </strong>Quantitative drinking indices appear to perform well at classifying alcohol use disorder (AUD) in both a large community adult and inpatient sample, robustly identifying AUD at rates much better than chance and above accepted clinical classification benchmarks, with limited differences by sex. These findings broadly support the potential clinical utility of quantitative drinking indicators in routine patient assessment.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drinking and pleasure: Interdisciplinarity points the way forward.","authors":"James Nicholls, Geoffrey Hunt","doi":"10.1111/add.70065","DOIUrl":"https://doi.org/10.1111/add.70065","url":null,"abstract":"","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acknowledging the crucial role of Max Glatt in the development of the Jellinek curve and the enduring relevance of his model of recovery from problem drinking.","authors":"Kevin McInerney, David Best","doi":"10.1111/add.70053","DOIUrl":"https://doi.org/10.1111/add.70053","url":null,"abstract":"<p><strong>Background and aims: </strong>Shortly after Max Glatt published a 'Chart of Alcohol Addiction and Recovery' in 1954, a misnomer emerged and it became known as the 'Jellinek Curve'. The current article aims to investigate the contributions that both Max Glatt and Morton Jellinek made towards the misnamed 'Jellinek Curve', how the misnomer may have emerged and the relevance of Jellinek's addiction concept and Glatt's model of recovery with contemporary theories of addiction and recovery.</p><p><strong>Method: </strong>Warlingham Park Hospital housed the first residential alcohol detoxification and rehabilitation unit in the UK's National Health Service, a model created and developed by Max Glatt. Much of the data that informed Glatt's model came from ex-Warlingham Park Hospital patients in recovery. The current article assumes an ethnographic approach. Literature searches were undertaken and the Warlingham Park Hospital archives were scrutinized.</p><p><strong>Conclusions: </strong>Max Glatt's 'Chart of Alcohol Addiction and Recovery' has mistakenly been referred to as the 'Jellinek Curve' for the last seven decades. 'The Matthew Effect' presents a possible explanation for the misnomer: the notion that eminent scientists are likely to receive greater credit than lesser-known scientists, regardless of their contribution. The recovery slope of Glatt's 'Chart' may be just as relevant today as when it was first published.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addiction Lives: Shekhar Saxena.","authors":"Virginia Berridge","doi":"10.1111/add.70034","DOIUrl":"https://doi.org/10.1111/add.70034","url":null,"abstract":"","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on Kersbergen et al.: Same Price, same choices? Proportional pricing and the heaviest drinkers.","authors":"Robyn Burton, Nick Sheron","doi":"10.1111/add.70046","DOIUrl":"https://doi.org/10.1111/add.70046","url":null,"abstract":"","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How effective are remote and/or digital interventions as part of alcohol and drug treatment and recovery support? A systematic review and meta-analysis.","authors":"Irene Kwan, Helen Elizabeth Denise Burchett, Wendy Macdowall, Preethy D'Souza, Claire Stansfield, Dylan Kneale, Katy Sutcliffe","doi":"10.1111/add.70021","DOIUrl":"https://doi.org/10.1111/add.70021","url":null,"abstract":"<p><strong>Background and aims: </strong>Although remote drug/alcohol interventions have been widely reviewed, their effectiveness specifically for people in treatment remains unclear. We aimed to systematically review the effectiveness of remote interventions (delivered by telephone or computer) in alcohol/drug treatment and recovery support.</p><p><strong>Methods: </strong>We searched 29 databases including Medline and PsycINFO for randomised controlled trials (RCTs) of remote interventions for adults diagnosed with alcohol/drug use disorder conducted in Organization for Economic Co-operation and Development (OECD) countries published 2004-2023. We grouped interventions according to whether they supplemented or replaced/partially replaced in-person care. We used random effects meta-analyses to estimate pooled odds ratios (OR) for relapse, and standardised mean differences (SMD) for days of alcohol/drug use. We appraised outcomes using Cochrane Risk of Bias 2.</p><p><strong>Results: </strong>We identified 34 RCTs (6461 participants) evaluating 42 remote interventions, with diverse therapeutic approaches. Over 70% of outcomes were judged to be at high risk-of-bias. When remote interventions supplemented in-person care, there was a 39% lower odds of relapse [17 interventions; OR 0.61; 95% confidence interval (CI) = 0.46, 0.81; P = 0.001; I² = 40.3%) and a reduction in the mean days of use (17 interventions; SMD -0.18; 95% CI = -0.28 to -0.08; P = 0.001; I² = 27.3%) compared with in-person care alone. When remote interventions replaced/partially replaced in-person care, there was a 49% lower odds of relapse (7 interventions; OR 0.51; 95% CI = 0.34, 0.76; P = 0.001; I² = 39.7%) and a very slight and uncertain reduction in mean days of use (8 interventions; SMD -0.08; 95% CI = -0.24 to 0.07; P = 0.301; I² = 48.4%) compared with in-person care. Subgroup analyses by type of substance and therapeutic approach were mixed and inconclusive.</p><p><strong>Conclusions: </strong>Remote interventions which supplement in-person alcohol/drug treatment appear to reduce relapse and days of use. The evidence is less conclusive regarding remote interventions that replace/partially replace in-person care due to a smaller body of evidence and uncertainty (days of use). High risk-of-bias means findings should be interpreted with caution.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying relevant intersections in relation to motivation and attempt to stop smoking by using a combination of methods to develop robust predictive models and resampling techniques: A cross-sectional study of the German population.","authors":"Sabina Ulbricht, Adrian Richter, Daniel Kotz, Sabrina Kastaun","doi":"10.1111/add.70045","DOIUrl":"https://doi.org/10.1111/add.70045","url":null,"abstract":"<p><strong>Aims: </strong>To illustrate robust intersections of co-occurring factors for two predictors of smoking cessation, motivation to stop smoking (MTSS) and past year-quit attempts (QA), by using means to develop robust predictive models such as bootstrap resampling, scoring rules to evaluate the predictive accuracy and spline functions.</p><p><strong>Design, setting and participants: </strong>Cross-sectional data from the German Study on Tobacco Use (DEBRA). Past-years smokers (≥18 years, n = 13 245) from 22 survey waves (2016-2020) were included. The sample (mean age 46.8 years, 46.7% women) was randomly divided into learning (70%) and validation data (30%). Less than 20% in both data sets had tried to stop smoking within the preceding 12 months.</p><p><strong>Measurements: </strong>Multinomial regression (for MTSS) and logistic regression (for QA) were used to evaluate whether age, sex, education, monthly net household income per person and the region of residence form intersections with relevant differences in the two outcomes.</p><p><strong>Findings: </strong>MTSS compared with the absence of MTSS was associated with middle [95% confidence interval (CI) = 1.02-1.39] and high education (95% CI = 1.37-1.98). Regarding MTSS, the highest probabilities were observed in participants aged 30 to 50 years from lower and middle (30-40 years) income groups. Regarding QA, the probability of at least one past-year QA was highest in females aged between 20 and 40 years and independent from educational level. Similar probabilities in males were seen only among those from the highest educated group. The predictive accuracy of the results was reduced by 3.1% for MTSS and 3.4% for QA when comparing learning with validation data.</p><p><strong>Conclusions: </strong>This German study provides compelling evidence linking highest motivation to stop smoking to those aged 30 to 50 years with lower or middle household income. Regardless of educational level, females' probabilities of reporting at least one past-year quit attempt appears to be highest in those aged 20 to 40 years. These findings highlight the need for adopting an intersectional approach when studying predictors of smoking cessation.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current and future trends in the consumption, sale and purchasing of alcohol-free and low-alcohol products in Great Britain, 2014 to 2023.","authors":"Luke B Wilson, Abigail K Stevely, Inge Kersbergen, Ellen McGrane, Esther C Moore, Rob E Pryce, Jamie Brown, John Holmes","doi":"10.1111/add.70041","DOIUrl":"https://doi.org/10.1111/add.70041","url":null,"abstract":"<p><strong>Background and aims: </strong>The UK Government has committed to reducing alcohol consumption by 2025 through increasing the availability of alcohol-free and low-alcohol (no/lo) drinks. This study estimated current and future trends in key indicators of the availability, sale, purchasing and consumption of no/lo products in Great Britain.</p><p><strong>Design: </strong>Seasonal autoregressive integrated moving average models of market research data and repeat-cross-sectional survey data on alcohol consumption.</p><p><strong>Setting: </strong>Great Britain (England, Scotland and Wales), January 2014-December 2025.</p><p><strong>Participants/measurements: </strong>The study used population-level data on no/lo product availability and sales in the on-trade (e.g. bars, pubs, clubs, restaurants), as well as the off-trade (e.g. supermarkets and convenience stores) (2014-2023), continuous household panel data on purchasing (n ≈ 30 000; 2018-2023) and repeat-cross-sectional survey data on consumption (n ≈ 80 000, 2020-2024) to construct monthly time series for seven indicators. It described current trends and forecast them to December 2025.</p><p><strong>Findings: </strong>All indicators showed increasing trends to 2025. The forecast level of each indicator in December 2025 was: Indicators 1 and 2: Percentage of alcoholic drinks sales volume that is no/lo products: 2.3% (50% Prediction Interval 2.1%-2.9%, off-trade) and 1.0% (50% Prediction Interval 0.8%-1.1%, on-trade); Indicator 3: Percentage of pubs selling draught no/lo products: 6.8% (50% Prediction Interval 6.1%-7.5%); Indicator 4: Percentage of households purchasing off-trade no/lo products but not alcoholic products: 12.3% (50% Prediction Interval 10.9%-13.6%); Indicator 5: Percentage of higher alcohol purchasing households that are increasing off-trade purchasing of no/lo products: 24.3% (50% Prediction Interval 21.3%-30.6%); Indicator 6: Percentage of households increasing off-trade purchasing of no/lo products and decreasing purchasing of alcoholic products: 1.8% (50% Prediction Interval 0.8%-2.8%); Indicator 7: Percentage of risky drinkers using no/lo products in most recent cut-down attempt: 42.4% (50% Prediction Interval 37.2%-53.3%).</p><p><strong>Conclusions: </strong>Consumption of alcohol-free and low-alcohol drinks is increasing in Great Britain but predicted to remain low in 2025 (estimated at 1.0% of on-trade and 2.3% of off-trade alcohol sales volume in servings by the end of 2025). There is some evidence that people are using no/lo drinks in attempts to reduce their alcohol consumption.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Considerations for implementing high-dose buprenorphine for opioid use disorder.","authors":"Suhanee Mitragotri, David T Zhu","doi":"10.1111/add.70051","DOIUrl":"https://doi.org/10.1111/add.70051","url":null,"abstract":"","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143661707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}