High potency cannabis flower use is associated with heavier consumption and risk for cannabis use disorder among young adults in California, United States

IF 5.3 1区医学 Q1 PSYCHIATRY

Addiction Pub Date : 2025-07-30 DOI:10.1111/add.70118

Michael S. Dunbar, Elizabeth J. D'Amico, Rachana Seelam, Jordan P. Davis, Eric R. Pedersen, Anthony Rodriguez, Beau Kilmer

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Abstract

Aims

To measure associations between frequency and quantity consumed of cannabis flower for different levels of delta-9-tetrahydrocannabinol (THC) concentration.

Design

Cross-sectional survey.

Setting

California, USA (survey fielded June 2022–July 2023).

Participants

Young adults (n = 512) with mean age 25.86 (standard deviation = 0.87) years, 48.04% female, from a California-based cohort study, who endorsed past-month cannabis flower use.

Measurements

Individuals completed survey items on cannabis use behavior (e.g. past-month use frequency, quantity consumed), symptoms of cannabis use disorder [using the Cannabis Use Disorder Identification Test - Revised (CUDIT-R)] and self-reported knowledge and perceived THC content (potency) of typical flower used. Multivariable linear and logistic regression models examined associations between perceived flower potency [rated on a scale from No THC (0) to Very High THC (5)], use behavior and CUDIT-R scores, adjusting for sociodemographic characteristics.

Findings

Nearly one in five respondents (18.55%) indicated that they did not know the THC potency of flower typically used. Among those who endorsed knowing potency, nearly half (46.76%) endorsed typically using High or Very High THC flower. Results from separate adjusted linear regression models showed that a one-point increase in the perceived THC potency scale was associated with 3.33 more use days per month [B = 3.33, (standard error, SE = 0.46), P < 0.0001], 0.13 more grams of flower used per day [B = 0.13 (SE = 0.04), P < 0.01] and 1.21 greater CUDIT-R scores [B = 1.21 (SE = 0.29), P < 0.0001].

Conclusions

Self-reported use of higher potency cannabis flower appears to be associated with more frequent and higher-quantity cannabis consumption and greater Cannabis Use Disorder Identification Test - Revised (CUDIT-R) scores, which is inconsistent with the notion that individuals titrate use of higher-potency cannabis.

Abstract Image

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在美国加利福尼亚州的年轻人中，高效力大麻花的使用与更大的消费量和大麻使用障碍的风险有关

目的测定不同浓度δ -9-四氢大麻酚（THC）的吸食频率和吸食量之间的关系。设计横断面调查。美国加利福尼亚州（调查于2022年6月至2023年7月进行）。参与者年轻成人（n = 512），平均年龄25.86岁（标准差= 0.87）岁，48.04%女性，来自加利福尼亚的队列研究，支持过去一个月使用大麻花。个人完成了关于大麻使用行为的调查项目（例如，过去一个月的使用频率、消耗的数量）、大麻使用障碍的症状[使用经修订的大麻使用障碍识别测试（CUDIT-R）]和自我报告所使用的典型花卉的知识和感知的四氢大麻酚含量（效力）。多变量线性和逻辑回归模型检验了感知花效价(从无THC（0)到非常高THC(5)评分）、使用行为和CUDIT-R评分之间的关系，并根据社会人口统计学特征进行了调整。近五分之一（18.55%）的受访者表示，他们不知道通常使用的花卉的四氢大麻酚效力。在那些认可知道效力的人中，近一半（46.76%）的人认可通常使用高或非常高的THC花。单独调整的线性回归模型的结果显示，感知THC效价量表每增加1点，每月使用时间增加3.33天[B = 3.33,（标准误差，SE = 0.46）， P < 0.0001]，每天使用花的克数增加0.13克[B = 0.13 (SE = 0.04), P < 0.01]， CUDIT-R评分增加1.21克[B = 1.21 (SE = 0.29), P < 0.0001]。结论：自我报告使用高效大麻花似乎与更频繁和更高数量的大麻消费以及更高的大麻使用障碍识别测试-修订（CUDIT-R）分数有关，这与个人滴定使用高效大麻的概念不一致。

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来源期刊

Addiction 医学-精神病学

CiteScore

10.80

自引率

6.70%

发文量

319

审稿时长

3 months

期刊介绍： Addiction publishes peer-reviewed research reports on pharmacological and behavioural addictions, bringing together research conducted within many different disciplines. Its goal is to serve international and interdisciplinary scientific and clinical communication, to strengthen links between science and policy, and to stimulate and enhance the quality of debate. We seek submissions that are not only technically competent but are also original and contain information or ideas of fresh interest to our international readership. We seek to serve low- and middle-income (LAMI) countries as well as more economically developed countries. Addiction’s scope spans human experimental, epidemiological, social science, historical, clinical and policy research relating to addiction, primarily but not exclusively in the areas of psychoactive substance use and/or gambling. In addition to original research, the journal features editorials, commentaries, reviews, letters, and book reviews.