Current Hypertension Reports最新文献

{"title":"Environmental Determinants of Sleep and Hypertension: A Critical Review of Evidence and Mechanisms.","authors":"Kushagra Vashist, Jelaina Shipman-Lacewell, Shenita Peterson, Kiara Phillips, Dayna A Johnson","doi":"10.1007/s11906-026-01366-7","DOIUrl":"10.1007/s11906-026-01366-7","url":null,"abstract":"<p><p>PURPOSE OF REVIEW: Examine current evidence on the impact of environmental exposures including noise, light at night, air pollution, temperature, metals, greenspace, and neighborhood on sleep and hypertension.  RECENT FINDINGS: Light exposure during sleep, air pollution (especially ozone), higher temperature, and neighborhood disadvantage were consistently associated with poor sleep; associations for noise (children), metals (adults), greenspace, and walkability were mixed. For hypertension, air pollution, increased ambient heat, and neighborhood disadvantage showed consistent associations whereas findings for noise, light, and greenspace had mixed findings. Neighborhood reinvestment, social cohesion, and safer environment was associated with healthier sleep and normal blood pressure.  Minoritized and low-socioeconomic status populations face greater environmental exposures and had higher risk of poor sleep and hypertension. Pregnancy represents a window of vulnerability to the effects of air pollution, heat, humidity, and metals on hypertension. Future research should employ personal sensors for better exposure assessments and longitudinal designs to determine causal pathways. </p>","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147716407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Resistance Training Provide Benefits that Are Comparable to Aerobic Exercise in Hypertension?","authors":"Hirofumi Tanaka, Rodrigo Ferrari","doi":"10.1007/s11906-026-01369-4","DOIUrl":"10.1007/s11906-026-01369-4","url":null,"abstract":"<p><p>PURPOSE OF REVIEW: Historically, blood pressure (BP) guidelines emphasized the implementation of aerobic exercise. However, more recent guidelines started highlighting the benefits of resistance exercise. The primary aim of this brief review is to determine if resistance training offers comparable benefits to aerobic exercise on BP in individuals with hypertension. RECENT FINDINGS: Aerobic exercise training consistently produces the greatest effect, lowering systolic/diastolic BP by ~ 7/5 mmHg in individuals with hypertension. Dynamic resistance training elicits more modest reductions (~ 2/2 mmHg), whereas isometric resistance training, though evaluated in fewer and smaller studies, has shown clinically meaningful reductions of ~ 5/5 mmHg. However, the impacts of resistance exercise training on ambulatory BP remain non-significant and marginal. Strategies to reduce BP should prioritize aerobic exercise rather than resistance training, especially when the primary goal is BP management. </p>","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13068723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147644407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attributable Risk of Hypertension for Cardiovascular Disease.","authors":"Hunter P Mace, Donald Clark","doi":"10.1007/s11906-026-01363-w","DOIUrl":"10.1007/s11906-026-01363-w","url":null,"abstract":"<p><p>PURPOSE OF REVIEW: Cardiovascular disease (CVD) remains the leading cause of mortality worldwide, and hypertension is a modifiable risk factor with the strongest association for developing heart disease. This review evaluates the attributable risk of hypertension for CVD at the population level and examines how this risk varies by demographic, geographic, and socioeconomic factors. Understanding the extent to which hypertension contributes to CVD can help inform targeted prevention and intervention treatment strategies. RECENT FINDINGS: Recent studies have examined the attributable risk of hypertension for CVD across different populations. Hypertension had the highest population attributable risk (PAR) and population attributable fraction (PAF) values for overall CVD, stroke, heart failure, and coronary heart disease, especially among Black adults, younger individuals, and residents of low- and middle-income countries. Although hypertension prevalence has increased over time, some high-income countries have observed a decline in its attributable risk for CVD. This decline is likely due to improved blood pressure management and public health interventions. In the US, recent data shows blood pressure control among adults remains low. Population-level interventions such as sodium restrictions in the food supply, standardized treatment protocols to improve blood pressure control, and improved healthcare access have been shown to mitigate the burden of hypertension. Despite advancements in awareness and treatment, hypertension continues to be a major driver of the global CVD burden. The meaningful attributable risk for CVD highlights the need for improved public health protocols. Interventions that combine clinical management with population-level prevention strategies offer the greatest potential for reducing disparities and improving cardiovascular outcomes. </p>","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13021759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147519950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-Dose Aspirin Recommendations for Preeclampsia Risk Reduction: A Systematic Review Focused on Black Patients : Current Hypertension Reports.","authors":"Yitian Zha, Natalie J Mikhailov, Krishna H Brucia, Juan Gao, Emily Alleman, Keith C Ferdinand","doi":"10.1007/s11906-026-01373-8","DOIUrl":"10.1007/s11906-026-01373-8","url":null,"abstract":"<p><p>PURPOSE: Daily low-dose aspirin (LDA) is guideline recommended for preeclampsia prevention, but racial/ethnic disparities persist in its implementation. This systematic review examines disparities in LDA prescription, recommendation and adherence for preeclampsia risk reduction among Black patients compared with other racial/ethnic groups in the United States. RECENT FINDINGS: Overall, LDA prescription/recommendation rates range widely across included studies, from 10.7% to 95% among eligible patients. Black patients are shown to have a similar prescription/recommendation rate compared to White patients. Adherence rates average around 70%, with Black patients showing lower adherence rates despite similar prescription/recommendation rates than White patients. Barriers identified included inconsistent counseling, limited access to prenatal care, and distrust of the healthcare system. While prescribing practices for LDA appear increasingly equitable across racial/ethnic groups, significant disparities remain in adherence among Black women, potentially contributing to worse maternal outcomes. Reducing these gaps requires culturally tailored patient education, improved physician–patient communication, and systems-level interventions that integrate adherence monitoring into prenatal care. </p>","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13002697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Updates in the 2025 AHA/ACC Hypertension Guideline.","authors":"Carly Brown, Donald Clark, Daniel W Jones","doi":"10.1007/s11906-026-01372-9","DOIUrl":"10.1007/s11906-026-01372-9","url":null,"abstract":"<p><p>PURPOSE OF REVIEW: Hypertension remains a leading cause of cardiovascular morbidity and mortality in the United States. The 2025 American Heart Association (AHA)/American College of Cardiology (ACC) Guideline for the Management of High Blood Pressure in Adults provides the first major update since 2017. It reveals new evidence in the diagnosis, risk assessment, and treatment of hypertension. This review summarizes key updates, contrasts them with prior recommendations, and discusses implications for clinical practice. RECENT FINDINGS: The 2025 AHA/ACC Hypertension Guideline introduces several major updates that reshape risk assessment, diagnosis, and treatment strategy. Adoption of the PREVENT risk calculator replaces the pooled cohort equations, improving cardiovascular risk estimation by incorporating renal function, statin use, and social drivers of health. Screening for primary aldosteronism is expanded to all patients with stage 2 or resistant hypertension, addressing underdiagnosis of this secondary cause. Renal denervation is introduced as an adjunctive option for select patients with resistant hypertension. The guideline also provides expanded recommendations for special populations, including those with chronic kidney disease, diabetes, pregnancy, and neurologic disorders. Enhanced emphasis on home blood pressure monitoring, lifestyle modification, and team-based care highlights the growing importance of patient engagement and coordinated care. The 2025 AHA/ACC Hypertension Guideline marks a pivotal shift toward risk-based, patient-centered hypertension management. It reinforces the need for tailored strategies that bridge clinical practice and population health. Effective implementation will depend on interdisciplinary collaboration and equitable access to preventative and therapeutic resources. </p>","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12995957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147472252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aorto-Renal Dysplasia in Childhood: The Overlap of Neurofibromatosis Type 1 and Pediatric Renovascular Hypertension.","authors":"Eden Singh, Kevin Meyers, Dawn M Coleman, Santhi K Ganesh","doi":"10.1007/s11906-025-01350-7","DOIUrl":"10.1007/s11906-025-01350-7","url":null,"abstract":"<p><p>PURPOSE OF REVIEW: This narrative review aims to summarize what is currently understood about Neurofibromatosis Type 1 (NF-1) and renovascular hypertension (RVH) in children, including clinical presentation and diagnosis, epidemiology, genetics, and management considerations including advances in treatment modalities. RECENT FINDINGS: Most of what is currently understood about NF-1 and arterial dysplasia leading to RVH relies on the inclusion of patients with NF-1 in single-institution reports. The management of pediatric RVH often requires multi-modal therapies inclusive of anti-hypertensive medications and revascularization for refractory cases, through catheter-based (i.e., endovascular) and open surgical means. There is a need to develop genotype-targeted guidelines for the diagnosis and management of pediatric aorto-renal dysplasia resulting in RVH in patients with NF-1. While our understanding of pediatric RVH and NF-1 has evolved over the past decade, critical research questions have emerged that encompass epidemiology, etiology and genetics. These research questions require immediate attention to establish and optimize standardized diagnostic and treatment guidelines. </p>","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12992459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic Opportunities Targeting the ACE2/Ang-(1-7)/MasR Pathway in Cardiometabolic Disease.","authors":"Thilina U Jayawardena, Dineth P Nagahawatta, Maria B Grant, Mark C Chappell, Gavin Y Oudit","doi":"10.1007/s11906-026-01364-9","DOIUrl":"10.1007/s11906-026-01364-9","url":null,"abstract":"<p><p>PURPOSE OF REVIEW: This review examines the protective angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas receptor axis of the renin–angiotensin system. We sought to integrate evidence from preclinical and early human studies on how activation of this pathway influences vascular, cardiac, renal, hepatic and metabolic health, and to identify methodological lessons for developing future therapies. RECENT FINDINGS: Animal models show that augmenting this axis improves endothelial function, limits cardiac remodelling, enhances insulin sensitivity, reduces renal injury and mitigates hepatic steatosis associate with MASH/NAFLD. Early-phase trials of recombinant angiotensin-converting enzyme 2 and angiotensin-(1–7) analogues demonstrate favourable safety profiles and clear pharmacodynamic target engagement but inconsistent immediate clinical effects. Emerging work highlights the value of biomarker ratios, gene and lifestyle based modulation and patient stratification strategies. Activation of the angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas receptor axis offers a promising route to address cardiometabolic disease. Filling gaps in long-term outcomes, receptor-specific mechanisms and precision patient selection could transform this counter-regulatory pathway into a cornerstone of next-generation therapies. </p>","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension Disparities in Immigrant and Refugee Populations: Screening, Treatment Access, and Cultural Barriers.","authors":"Oluwabunmi Ogungbe, Oluwalonimi Adebowale, Ruth-Alma N Turkson-Ocran, Thomas Hinneh, Faith E Metlock, Tiwaloluwa A Ajibewa, Abeer Alharthi, Janice Dugbartey, Asma Rayani, Elohor Oborevwori, Biruk Teshome, Binu Koirala, Diana-Lyne Baptiste, Tala Al-Rousan, Yvonne Commodore-Mensah","doi":"10.1007/s11906-025-01344-5","DOIUrl":"10.1007/s11906-025-01344-5","url":null,"abstract":"<p><p>Hypertension affects over 120 million Americans, yet immigrant and refugee populations face disproportionate barriers to effective hypertension care. With nearly 48 million immigrants and growing refugee populations in the US, understanding these disparities has become a crucial public health issue. This review synthesizes current evidence on hypertension disparities among immigrant and refugee populations, examining barriers across the hypertension care cascade from screening through control, and discusses promising interventions. Hypertension prevalence varies across immigrant populations. These populations face multiple barriers throughout care: limited screening access, delayed treatment initiation, and poor long-term control. The intersectionality of structural barriers, cultural factors, economic limitations, and healthcare system limitations creates a cumulative cycle of disadvantages. The political threats and \"othering\" process, discrimination and cultural marginalization, further worsen these challenges, affecting trust, care-seeking behavior, and treatment adherence.Evidence-based interventions show that culturally responsive, community-centered approaches can meaningfully reduce disparities. Community health worker programs achieved remarkable improvements in blood pressure control among immigrant populations. Technology-enhanced interventions, partnerships with faith-based organizations, culturally adapted educational resources, and Clinician cultural humility training often show promising results. However, addressing these disparities requires approaches at the individual, community, healthcare system, and policy levels to be implemented simultaneously. There need to be a sustained commitment to health equity, recognizing that the health of immigrants affects community well-being and the stability of the national and global healthcare system.</p>","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Insights Into Pediatric Hypertension, Cardiac Consequences, and Physical Activity.","authors":"Douglas R Corsi, Andrew O Agbaje","doi":"10.1007/s11906-026-01370-x","DOIUrl":"10.1007/s11906-026-01370-x","url":null,"abstract":"<p><p>PURPOSE OF REVIEW: To summarize important novel but controversial discoveries in pediatric hypertension and prevention. This review also aims to provide some answers to previously unexpected findings in randomized clinical trials that failed to lower blood pressure in youth. RECENT FINDINGS: Emerging longitudinal investigations have elucidated the temporal progression of cardiac structural changes, revealing that arterial stiffness precedes the development of hypertension and cardiac remodeling. These temporal insights have important implications for physical activity interventions, as traditional recommendations emphasizing moderate-to-vigorous physical activity to lower blood pressure have demonstrated limited efficacy in randomized controlled trials. Recent evidence suggests that light physical activity provides superior blood pressure-lowering capacity compared to moderate-to-vigorous physical activity due to the confounding effect of muscle mass. Moreover, sedentary behavior may be a causal risk factor for progressive cardiovascular deterioration.  Elevated blood pressure and hypertension during childhood and adolescence represent a critical risk factor for premature cardiovascular morbidity and mortality in adulthood. While the association between pediatric hypertension and adverse cardiovascular events is well-established, the temporal sequencing of pathophysiological mechanisms leading from blood pressure elevation to end-organ damage remains unclear. This comprehensive review synthesizes emerging evidence regarding the temporal relationships between pediatric hypertension and cardiac consequences, highlighting temporal trends that could inform evidence-based physical activity interventions for optimizing cardiovascular health trajectories from childhood through young adulthood. </p>","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12953251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147343983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension in Women Across the Life Cycle: Unique Aspects and Challenges.","authors":"Rachel M Bond, Vikramjit Purewal, Natalie Cameron, Kardie Tobb, Demilade Adedinsewo, Ijeoma Isiadinso, Kameelah Phillips","doi":"10.1007/s11906-026-01362-x","DOIUrl":"10.1007/s11906-026-01362-x","url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a major driver of cardiovascular morbidity and mortality in women, with risk trajectories that evolve across the female life course. From reproductive years through menopause, sex-specific biological, hormonal, and social factors contribute to unique patterns of blood pressure risk and cardiovascular vulnerability.</p><p><strong>Objective: </strong>To provide a life-course review of hypertension in adult women and highlight stage-specific risk factors, clinical considerations, and opportunities for prevention and management.</p><p><strong>Content: </strong>Women experience distinct exposures that influence hypertension risk, including hypertensive disorders of pregnancy, adverse pregnancy outcomes, psychosocial stressors, cardiometabolic changes, and the transition through menopause. This review integrates key recommendations from the 2025 American College of Cardiology/American Heart Association High Blood Pressure Guideline and emphasizes practical, stage-specific approaches to screening, risk stratification, and treatment tailored to women.</p><p><strong>Conclusions: </strong>A life-stage-specific, sex-informed approach to hypertension is essential to improve early identification, optimize treatment, and reduce long-term cardiovascular risk in women. Addressing persistent evidence gaps and prioritizing implementation of sex-specific care strategies will be critical to advancing equitable cardiovascular outcomes.</p>","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12923406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}