Current Hypertension Reports最新文献

A Scoping Review of Asymptomatic Hypertension: Definitions, Diagnosis, and Management in the Emergency Department. 无症状高血压的范围回顾：定义、诊断和急诊部门的管理。

IF 3.9 2区医学

Current Hypertension Reports Pub Date : 2025-06-17 DOI: 10.1007/s11906-025-01335-6

Aleksandra Degtyar, Marceé E Wilder, Lynne D Richardson, Kimberly T Souffront

{"title":"A Scoping Review of Asymptomatic Hypertension: Definitions, Diagnosis, and Management in the Emergency Department.","authors":"Aleksandra Degtyar, Marceé E Wilder, Lynne D Richardson, Kimberly T Souffront","doi":"10.1007/s11906-025-01335-6","DOIUrl":"https://doi.org/10.1007/s11906-025-01335-6","url":null,"abstract":"Background: This scoping review examines the existing literature to reveal consensus or absence thereof regarding the definition and management strategies for asymptomatic hypertension.Methods: The review used Joanna Briggs Institute guidelines. We searched the CINAHL (EBSCO), Scopus, Ovid EMBASE, and PubMed (MEDLINE) databases using keywords and index terms to identify adult patients with hypertension in an emergency or outpatient setting. After review and quality assessment, we included 35 texts.Results: The definition of \"asymptomatic hypertension\" varied widely. There was significant variation in which society or academic guideline served as the reference and what the blood pressure cut offs were; all specified a lack of end-organ damage. End-organ damage was poorly defined- studies instead described the absence of hypertensive emergency. Of the texts which provided recommendations, all recommended a thorough history and physical examination. Only one study recommended additional testing for asymptomatic patients. Treatment recommendations relied predominantly on ACEP clinical policy, with a majority of studies advocating for gradual reduction of blood pressure as well as referral for outpatient management.Conclusion: Unified guidelines on the definition and management of asymptomatic hypertension are needed to ensure effective and consistent patient care. There is no consensus for diagnostic testing in patients with a negative history and physical exam, nor whether treatment should be initiated in the emergency department. Addressing this gap would enhance clinical outcomes and streamline healthcare processes across systems. Future research should focus on establishing consensus and developing management strategies that are adaptable to both emergency and primary care environments.","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"27 1","pages":"18"},"PeriodicalIF":3.9,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex Difference of Alcoholic Hypertension: Mechanism and Targeted Therapy. 酒精性高血压的性别差异：机制和靶向治疗。

IF 3.9 2区医学

Current Hypertension Reports Pub Date : 2025-06-10 DOI: 10.1007/s11906-025-01334-7

Lu Xiao, Sicong Yang, Yali Song, Jia Xiao

{"title":"Sex Difference of Alcoholic Hypertension: Mechanism and Targeted Therapy.","authors":"Lu Xiao, Sicong Yang, Yali Song, Jia Xiao","doi":"10.1007/s11906-025-01334-7","DOIUrl":"https://doi.org/10.1007/s11906-025-01334-7","url":null,"abstract":"Purpose of review: This review provides a critical examination of the sex-specific impact of alcohol consumption on the development and progression of hypertension. Specifically, it elucidates the differential roles of alcohol metabolism and blood pressure regulatory mechanisms in men and women. Finally, it explores promising sex-specific therapeutic strategies for the management of alcoholic hypertension.Recent findings: Emerging evidence indicates significant sex-based disparities in alcohol pharmacokinetics and pharmacodynamics, with women exhibiting heightened susceptibility to alcohol-induced cardiovascular sequelae. Crucially, key mechanistic insights reveal the differential modulation of the renin-angiotensin-aldosterone system (RAAS), oxidative stress pathways, and the intricate interplay of sex hormones, including the protective effects of estrogen and the potential pro-hypertensive effects of testosterone. Consequently, contemporary therapeutic avenues are increasingly focusing on targeting these sex-specific pathophysiological mechanisms. Alcoholic hypertension manifests with distinct sex-related etiologies and underlying mechanisms, necessitating the development of tailored therapeutic interventions. Effective management strategies should prioritize addressing sex-specific differences in oxidative stress, RAAS activation, and the implementation of personalized lifestyle modifications.","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"27 1","pages":"17"},"PeriodicalIF":3.9,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secondary Hypertension in Children-Identifying and Investigating at Risk Children. 儿童继发性高血压——识别和调查高危儿童。

IF 3.9 2区医学

Current Hypertension Reports Pub Date : 2025-05-31 DOI: 10.1007/s11906-025-01333-8

Fang Chao Linda Ding, Blake J Sandery

{"title":"Secondary Hypertension in Children-Identifying and Investigating at Risk Children.","authors":"Fang Chao Linda Ding, Blake J Sandery","doi":"10.1007/s11906-025-01333-8","DOIUrl":"https://doi.org/10.1007/s11906-025-01333-8","url":null,"abstract":"Purpose of review: We aim to review the most recent literature on demographic features and diagnostic workup of children with secondary hypertension, in order to provide a framework for health providers to determine which hypertensive pediatric patients warrant further investigation for secondary causes. By highlighting the utility of various diagnostic investigations, we aim to minimize unnecessary testing burden.Recent findings: A recent meta-analysis revealed that hypertensive children and adolescents with any of the following features were at increased risk of secondary hypertension: < 6 years of age, history of prematurity, family history of secondary hypertension, body mass index (BMI) < 10th percentile. Based on available evidence, we suggest a testing schema that is stratified by both age and BMI. Limited evidence suggest renal ultrasound may be one of the most useful initial investigations for secondary causes in asymptomatic hypertensive children. Lipid profile in overweight/obese children, and echocardiogram for end organ involvement may have high yield of abnormal results. Further studies on the diagnostic utility of tests for secondary hypertension are required, as the current body of evidence is limited.","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"27 1","pages":"16"},"PeriodicalIF":3.9,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Remote Blood Pressure Monitoring in Pregnancies at Risk of Developing Preeclampsia. 远程血压监测妊娠发生子痫前期的风险。

IF 3.9 2区医学

Current Hypertension Reports Pub Date : 2025-05-28 DOI: 10.1007/s11906-025-01332-9

Theepika Rajkumar, Annemarie Hennessy, Angela Makris

{"title":"Remote Blood Pressure Monitoring in Pregnancies at Risk of Developing Preeclampsia.","authors":"Theepika Rajkumar, Annemarie Hennessy, Angela Makris","doi":"10.1007/s11906-025-01332-9","DOIUrl":"10.1007/s11906-025-01332-9","url":null,"abstract":"Purpose of review: This review examines the literature on remote blood pressure monitoring (RBPM) for pregnant women at high risk of hypertensive disorders of pregnancy (HDP).Recent findings: Hypertensive disorders of pregnancy are a leading cause of maternal and perinatal morbidity. High risk women often require frequent outpatient review for blood pressure monitoring which can be resource-intensive. RBPM is an organised framework which allows patients to monitor their own blood pressure with clinician guidance, improving healthcare utilisation and potentially saving healthcare costs without worsening maternal and fetal outcomes. Following the COVID-19 pandemic and the growing research interest in mobile health, RBPM has been integrated into international guidelines for managing high-risk pregnancies. Yet there is significant heterogeneity across RBPM frameworks described in the literature, and a lack of clear guidance on the development and implementation of this strategy. RBPM offers promising additional surveillance for high-risk pregnant women. However, challenges remain in its safe implementation, including patient selection, technology, costs, and adequate training to ensure accuracy in blood pressure readings.","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"27 1","pages":"15"},"PeriodicalIF":3.9,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12119646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"Gut Microbiota as a Therapeutic Target for Hypertension: Challenges and Insights for Future Clinical Applications" "Gut Microbiota and Hypertension Therapy". “肠道微生物群作为高血压的治疗靶点：对未来临床应用的挑战和见解”“肠道微生物群与高血压治疗”。

IF 3.9 2区医学

Current Hypertension Reports Pub Date : 2025-04-22 DOI: 10.1007/s11906-025-01331-w

Elsayed M Mahgoup

{"title":"\"Gut Microbiota as a Therapeutic Target for Hypertension: Challenges and Insights for Future Clinical Applications\" \"Gut Microbiota and Hypertension Therapy\".","authors":"Elsayed M Mahgoup","doi":"10.1007/s11906-025-01331-w","DOIUrl":"https://doi.org/10.1007/s11906-025-01331-w","url":null,"abstract":"Purpose of review: Systemic hypertension is a major risk factor for cardiovascular disease and remains challenging to manage despite the widespread use of antihypertensive medications and lifestyle modifications. This review explores the role of gut microbiota in hypertension development and regulation, highlighting key mechanisms such as inflammation, gut-brain axis modulation, and bioactive metabolite production. We also assess the potential of microbiota-targeted therapies for hypertension management.Recent findings: Emerging evidence indicates that microbial dysbiosis, high-salt diets, and gut-derived metabolites such as short-chain fatty acids (SCFAs) and bile acids significantly influence blood pressure regulation. Preclinical and early clinical studies suggest that interventions targeting gut microbiota, including probiotics, prebiotics, synbiotics, fecal microbiota transplantation (FMT), and dietary modifications, may help modulate hypertension. However, variability in gut microbiota composition among individuals and limited human trial data pose challenges to translating these findings into clinical practice. While microbiota-based therapies show promise for hypertension management, further research is needed to establish their efficacy and long-term effects. Large-scale, standardized clinical trials are crucial for understanding the therapeutic potential and limitations of gut microbiota interventions. A deeper understanding of the gut-hypertension axis could lead to novel, personalized treatment strategies for hypertension.","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"27 1","pages":"14"},"PeriodicalIF":3.9,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypertension in Childhood Cancer Survivors: Causes, Screening, and Management. 儿童癌症幸存者的高血压：原因、筛查和管理。

IF 3.9 2区医学

Current Hypertension Reports Pub Date : 2025-03-14 DOI: 10.1007/s11906-025-01330-x

Natalie L Wu, Coral D Hanevold

{"title":"Hypertension in Childhood Cancer Survivors: Causes, Screening, and Management.","authors":"Natalie L Wu, Coral D Hanevold","doi":"10.1007/s11906-025-01330-x","DOIUrl":"10.1007/s11906-025-01330-x","url":null,"abstract":"Purpose of review: Survivors of childhood cancer and hematopoietic cell transplant are at risk for developing chronic health conditions, including hypertension. Studies have identified hypertension as an influential risk factor for late kidney dysfunction and cardiovascular disease in childhood cancer survivors. The overall risk of hypertension depends on the specific cancer treatment, from chemotherapy to surgery to radiation. In this report, we aim to review the main causes of hypertension in childhood cancer survivors, with a focus on newer therapies, as well as the current recommendations for screening and management of hypertension in this patient population.Recent findings: Novel targeted therapies and immunotherapies are being increasingly used in pediatric cancer treatment, with unclear impact on long-term health. Screening guidelines for hypertension in the survivor population have been issued by various childhood cancer cooperative groups based on best available evidence and expert opinion. Newer studies have focused on individual risk prediction, which may help improve the diagnosis and management of hypertension, particularly in higher-risk individuals. Despite the importance of hypertension as one of the few modifiable risk factors for cardiovascular and renal health, studies have yet to define optimal blood pressure targets, screening parameters, or management strategies in childhood cancer survivors. Additionally, further studies are needed to demonstrate improvement in outcomes following interventions for hypertension specifically in this patient population.","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"27 1","pages":"13"},"PeriodicalIF":3.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypertension, Obesity, and Target Organ Injury in Children: An Emerging Health Care Crisis. 儿童高血压、肥胖症和靶器官损伤：新出现的医疗危机。

IF 3.9 2区医学

Current Hypertension Reports Pub Date : 2025-02-27 DOI: 10.1007/s11906-025-01329-4

Andrew H Tran, Aaron Walsh, Elaine M Urbina

{"title":"Hypertension, Obesity, and Target Organ Injury in Children: An Emerging Health Care Crisis.","authors":"Andrew H Tran, Aaron Walsh, Elaine M Urbina","doi":"10.1007/s11906-025-01329-4","DOIUrl":"10.1007/s11906-025-01329-4","url":null,"abstract":"Purpose of review: To review data regarding the association between hypertension and childhood obesity on target organ damage. We will also review data regarding the impact of intervening on hypertension and childhood obesity on target organ damage.Recent findings: The prevalence of hypertension and obesity are rising in children despite efforts to address these risk factors. Health disparities play a role in contributing to the rise in prevalence. Hypertension and obesity promote pro-inflammatory cytokines that activate the renin-angiotensin-aldosterone system and sympathetic nervous system which result in adverse effects on blood pressure regulation and renal function. Adverse cardiac, vascular, renal, neurocognitive, and retinal changes can be seen with elevated blood pressure. Recent intervention studies are few, but adequate treatment of hypertension and obesity can result in improvement in target organ damage. Hypertension and obesity have significant impacts upon target organs. Interventions to decrease blood pressure and treat obesity are associated with reductions in left ventricular hypertrophy, improvement in measures of systolic and diastolic function, and improvement in renal outcomes. Appropriate screening and management of these conditions can lessen potential future cardiovascular impact.","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"27 1","pages":"12"},"PeriodicalIF":3.9,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11868356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urinary Biomarkers Of Kidney Function As Predictors Of Cardiovascular Health: A Systematic Review. 预测心血管健康的肾功能尿液生物标志物：系统回顾

IF 3.9 2区医学

Current Hypertension Reports Pub Date : 2025-02-21 DOI: 10.1007/s11906-025-01328-5

A Degenaar, R Kruger, A Jacobs, C M C Mels

{"title":"Urinary Biomarkers Of Kidney Function As Predictors Of Cardiovascular Health: A Systematic Review.","authors":"A Degenaar, R Kruger, A Jacobs, C M C Mels","doi":"10.1007/s11906-025-01328-5","DOIUrl":"10.1007/s11906-025-01328-5","url":null,"abstract":"Purpose of review: The growing burden of cardiovascular diseases has become a significant concern in both adult and youth populations. Urinary biomarkers of kidney function could provide useful insights that may aid in the early identification of individuals at higher risk of adverse cardiovascular outcomes. This systematic review aimed to assess associations between urinary biomarkers of kidney function and different measures of cardiovascular health.Recent findings: PubMed, Scopus, and EBSCOhost were searched for articles published between January 2018 and December 2023. Studies exploring associations between urinary kidney biomarkers (alpha-1 microglobulin (uA1M), neutrophil gelatinase-associated lipocalin (uNGAL), uromodulin (uUMOD) and CKD273 classifier) and measures of cardiovascular health (blood pressure and markers of target organ damage) were included. We identified 1186 articles, with 22 studies eligible for inclusion. Among 12 studies reporting associations between uA1M and measures of cardiovascular health, six studies indicated positive associations with office blood pressure and three studies observed associations with different markers of target organ damage. Out of the nine studies that explored the link between uUMOD and cardiovascular health parameters, four found negative associations between uUMOD and blood pressure. With regard to uNGAL, only two out of the seven studies analysed reported varying associations with blood pressure, while neither of the two studies focusing on CKD273 observed any statistically significant results. Biomarkers of kidney tubule function, represented by uA1M and uUMOD, are relevant in the setting of cardiovascular health and should be assessed for utilisation in clinical practice to identify adverse cardiovascular outcomes at an early stage allowing for timely intervention.","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"27 1","pages":"11"},"PeriodicalIF":3.9,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with preeclampsia and the hypertensive disorders of pregnancy amongst Indigenous women of Canada, Australia, New Zealand, and the United States: A systematic review and meta-analysis. 与加拿大、澳大利亚、新西兰和美国土著妇女妊娠期子痫前期和高血压疾病相关的因素：一项系统回顾和荟萃分析

IF 3.9 2区医学

Current Hypertension Reports Pub Date : 2025-02-20 DOI: 10.1007/s11906-025-01327-6

Jacqueline Stephens, Eleonora Dal Grande, Tayla Roberts, Marianne Kerr, Celine Northcott, Tahlia Johnson, Jessie Sleep, Courtney Ryder

{"title":"Factors associated with preeclampsia and the hypertensive disorders of pregnancy amongst Indigenous women of Canada, Australia, New Zealand, and the United States: A systematic review and meta-analysis.","authors":"Jacqueline Stephens, Eleonora Dal Grande, Tayla Roberts, Marianne Kerr, Celine Northcott, Tahlia Johnson, Jessie Sleep, Courtney Ryder","doi":"10.1007/s11906-025-01327-6","DOIUrl":"10.1007/s11906-025-01327-6","url":null,"abstract":"Purpose of the review: Preeclampsia and the Hypertensive Disorders of Pregnancy (HDP) occur more frequently amongst Indigenous women and can have short- and long-term impacts on maternal and infant health and wellbeing. To understand factors associated with increased risk for Indigenous women a systematic review and meta-analysis was conducted. The PRISMA guidelines were adhered to, and the review protocol was registered on PROSPERO (Registration CRD42023381847). EndNote, Covidence and Excel were used to screen and extract data, with studies assessed using JBI critical appraisal tools.Recent findings: Seven studies from Canada, Australia, and the United States (none from New Zealand) were included in this review. Meta-analysis showed women classified as overweight (OR 1.32, 95% CI: 1.09-1.60), obese (OR 1.88, 95% CI: 1.57-2.25), or having high mean BMI (MD 3.02 95% CI: 1.72-4.31), high mean systolic blood pressure (MD 15.19 95% CI: 12.83-17.541), or high mean diastolic blood pressure (MD 15.26 95% CI: 13.05-17.47), pre-pregnancy diabetes (OR 3.63, 95% CI: 1.66-17.94), or high microalbuminuria (OR 2.76, 95% CI: 1.40-5.43) were more likely to be diagnosed with preeclampsia. Smoking (OR 0.77, 95% CI: 0.58-1.03), alcohol consumption (OR 1.70, 95% CI: 0.76-3.81), and gestational diabetes (OR 1.74, 95% CI: 0.90-3.37) were not associated with preeclampsia. Understanding factors associated with increased preeclampsia/HDP risk amongst Indigenous women is important to minimising adverse perinatal events and future health complications. This review demonstrates current gaps in the evidence, specifically in relation to social, economic, and environmental factors.","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"27 1","pages":"10"},"PeriodicalIF":3.9,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does Nocturnal Blood Pressure Matter in Retinal Small Vessels? A Systematic Review and Meta-Analysis of the Literature. 夜间血压对视网膜小血管有影响吗？文献的系统回顾与元分析。

IF 3.9 2区医学

Current Hypertension Reports Pub Date : 2025-01-18 DOI: 10.1007/s11906-025-01326-7

Christina Antza, Smaro Palaska, Panagiota Anyfanti, Dimitris Triantis, Stavros Fyntrilakis, Yusuf ZiyaSener, Vasilios Kotsis

{"title":"Does Nocturnal Blood Pressure Matter in Retinal Small Vessels? A Systematic Review and Meta-Analysis of the Literature.","authors":"Christina Antza, Smaro Palaska, Panagiota Anyfanti, Dimitris Triantis, Stavros Fyntrilakis, Yusuf ZiyaSener, Vasilios Kotsis","doi":"10.1007/s11906-025-01326-7","DOIUrl":"10.1007/s11906-025-01326-7","url":null,"abstract":"Purpose of the review: Τhe association between nocturnal blood pressure (BP) and alterations in the retinal microvasculature remains understudied, with few available studies to provide conflicting results. Therefore, we conducted a systematic review and meta-analysis to determine whether an association exists between retinal microvascular alterations and nocturnal BP patterns, determined by 24h ambulatory BP measurement.Recent findings: Our search concluded to 1002 patients (6 studies). A total of 3 studies (411 patients) were enrolled in the meta-analysis. Central retinal arteriolar equivalent found to be not different between patients with and without dipping status (mean differences [MD]: -0.01; 95% CI: -0.23 to 0.20; I²=0%; P < 0.610). Regarding central retinal venular equivalent, dippers showed significantly lower values compared to non-dippers (MD: -0.25; 95% CI: -0.47 to -0.03; I²=0%; P < 0.024). For the comparison between nighttime and daytime BP regarding the damage in small retinal vessels, we identified only 5 studies. Due to different evaluated outcomes as well as due to the heterogeneity of outcomes and different grouping of patients based on different BP cut-off values, these results couldn't be analyzed quantitatively. In summary, this is the first effort to summarize evidence on the effects of day-to-night variation of BP on the retinal small vessels. According to the findings of the present systematic review and meta-analysis, non-dipping status may be associated with retinal venular dilatation, and elevated nighttime BP with retinal arteriolar narrowing. Further studies are warranted to elucidate the impact of nocturnal BP patterns in the retinal microvasculature.","PeriodicalId":10963,"journal":{"name":"Current Hypertension Reports","volume":"27 1","pages":"9"},"PeriodicalIF":3.9,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0