Current Chemistry Letters最新文献_第3页

Silica-zinc chloride (SiO2-ZnCl2) catalyzed Michael addition reaction of active methylene compounds to β-nitrostyrenes: Synthesis of functionalized pyrazole derivatives 二氧化硅-氯化锌(SiO2-ZnCl2)催化活性亚甲基化合物与β-硝基苯乙烯的Michael加成反应:功能化吡唑衍生物的合成

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2022.10.001

V. Krishnan, Santha Kumari Merugu, V. K. Reddy, H. Bollikolla

引用次数: 0

Isotherms, kinetics, and thermodynamics of methionine adsorption onto poorly crystalline hydroxyapatite with different Ca/P ratios 不同钙磷比下蛋氨酸在低结晶羟基磷灰石上吸附的等温线、动力学和热力学

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.4.003

A. E. Rhilassi, Oumaima Oukkass, M. Bennani-Ziatni

{"title":"Isotherms, kinetics, and thermodynamics of methionine adsorption onto poorly crystalline hydroxyapatite with different Ca/P ratios","authors":"A. E. Rhilassi, Oumaima Oukkass, M. Bennani-Ziatni","doi":"10.5267/j.ccl.2023.4.003","DOIUrl":"https://doi.org/10.5267/j.ccl.2023.4.003","url":null,"abstract":"The adsorption properties of hydroxyapatite of low crystallinity towards methionine have been examined. The chemical composition of hydroxyapatite was taken as an experimental variable in order to have a point of view on the parameters of the adsorption process and the mechanisms established between adsorbent-adsorbate. The adsorption kinetics are relatively fast, and the high amounts adsorbed at saturation are obtained for non-stoichiometric hydroxyapatite, containing more HPO42- ions and having a high specific surface area. The good agreement of the experimental data with kinetic models confirms that the mechanism can be perfectly described by pseudo-second-order kinetics. Adsorption isotherm models show that Langmuir's model gives a better fit of experimental data compared to that of Freundlich, Temkin and Dubinin-Kaganer-Radushkevich. Fourier transform infrared spectroscopy confirmed the interaction between the -COO- ions of methionine and the Ca2+ ions of hydroxyapatite. The thermodynamic parameters, the isoelectric point of methionine and the point of zero charge of hydroxyapatite with different Ca/P ratios show that the adsorption process is considered spontaneous, exothermic and often controlled by physisorption with interactions electrostatic.","PeriodicalId":10942,"journal":{"name":"Current Chemistry Letters","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84900273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insecticidal activity and structure activity relationship study of some synthesized hydrazone, dihydropyridine and 3-cyano-1, 4-dihydro-pyradazin-4-one derivatives against Aphis nerii 合成的腙类、二氢吡啶类和3-氰基- 1,4 -二氢吡达嗪-4- 1类衍生物对灰蚜的杀虫活性及构效关系研究

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.2.003

M. El-Gaby, Modather F. Hussein, Faraghally A. Faraghally, A. Drar, Mohamed A Gad

引用次数: 2

Insecticidal efficacy and structure activity relationship study of some synthesized cyano-benzylidene and bisbenzylidene derivatives against Aphis nerii 合成的几种氰亚苄基和双亚苄基衍生物对灰蚜的杀虫效果及构效关系研究

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.3.003

M. El-Gaby, M. Bakry, Modather F. Hussein, Faraghally A. Faraghally, A. Khalil, Mohamed A Gad, A. Drar

引用次数: 2

Design, synthesis, and anti-bacterial activities of piperazine based phthalimide derivatives against superbug-Methicillin-Resistant Staphylococcus aureus 哌嗪类酞酰亚胺衍生物的设计、合成及其对超级细菌耐甲氧西林金黄色葡萄球菌的抗菌活性研究

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2022.9.005

H. Prasad, A. Ananda, Amogh Mukarambi, Navyatha Prashanth Gaonkar, S. Sumathi, H. P. Spoorthy, P. Mallu

{"title":"Design, synthesis, and anti-bacterial activities of piperazine based phthalimide derivatives against superbug-Methicillin-Resistant Staphylococcus aureus","authors":"H. Prasad, A. Ananda, Amogh Mukarambi, Navyatha Prashanth Gaonkar, S. Sumathi, H. P. Spoorthy, P. Mallu","doi":"10.5267/j.ccl.2022.9.005","DOIUrl":"https://doi.org/10.5267/j.ccl.2022.9.005","url":null,"abstract":"A series of piperazine-based phthalimide derivatives 5 (a-l) were synthesized and extensively characterized using a variety of spectrum methods, including LC-MS, 1H-NMR, 13C-NMR, and FT-IR. All the derivatives were examined for their physicochemical, pharmacokinetic, bio-activity score, and PASS analysis. The 5e piperazine-based phthalimide derivative demonstrated promising antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) in the in vitro antibacterial studies. In comparison to streptomycin and bacitracin (10 µg/mL), the minimum inhibitory concentration of 5e against MRSA was discovered to be 45±0.15 micro g/ml. The anti-MRSA activity was validated with membrane damage studies by using SEM, and in silico docking studies were against 3VMT and 6FTB proteins of MRSA. In the toxicity study, 5e derivatives were evaluated against L6 cell lines. The results of the studies show the synthesized 2-(2-(4-((4-chlorophenyl) sulfonyl) piperazin-1-yl) ethyl) isoindoline-1,3-dione (5e) can be used for the development of anti-MRSA drugs.","PeriodicalId":10942,"journal":{"name":"Current Chemistry Letters","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74165863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Synthesis, characterization, and biological activities of five new trivalent lanthanide complexes of hydrazine and 3,3’-thiodipropanoic acid 五种新的联氨和3,3 ' -硫代二丙酸三价镧系配合物的合成、表征和生物活性

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.5.003

K. Kumar, S. Murugesan, T. Muneeswaran, C. M. Ramakritinan

{"title":"Synthesis, characterization, and biological activities of five new trivalent lanthanide complexes of hydrazine and 3,3’-thiodipropanoic acid","authors":"K. Kumar, S. Murugesan, T. Muneeswaran, C. M. Ramakritinan","doi":"10.5267/j.ccl.2023.5.003","DOIUrl":"https://doi.org/10.5267/j.ccl.2023.5.003","url":null,"abstract":"Some new hydrazine complexes of trivalent lanthanide 3,3’-thiodipropanoates of empirical formulae [M(N2H5)(tdp)2] and [Pr(N2H5)(tdp)2·H2O], where M = La, Ce, Sm and Nd, H2tdp = 3,3’-thiodipropanoic acid, have been prepared and characterized by elemental analysis, mass, FTIR, Raman and electronic spectral, powder X-ray diffraction, scanning electron microscopy (SEM) and simultaneous TG–DTA techniques. The presence of bidentate carboxylate anion and coordinated N2H5 in these complexes are confirmed by IR spectra. TGA/DTA results confirmed that all the rare earth metal complexes give the corresponding metal carbonate (heating up to 1000 °C) through a metal oxalate intermediate. SEM images of Pr2O3 residue obtained from its complex show nano-sized clusters, thus the complex may be used as a precursor for nano-Pr2O3 preparation. The synthesized complexes show good antimicrobial activity against six bacteria (Bacillus cereus, Staphylococcus aureus, Proteus vulgaris, Pseudomonas aeruginosa, Escherichia coli, and Serratia species) and four fungi (Candida albicans, Aspergillus niger, Aspergillus fumigatus, and Penicillium variance) as assessed by in vitro biological activity.","PeriodicalId":10942,"journal":{"name":"Current Chemistry Letters","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74313227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and characterization of λ-shaped azo liquid crystals: The effect of terminal alkoxy group λ型偶氮液晶的合成与表征:末端烷氧基的影响

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.1.007

Akshay Thakor, V. Sharma, Suryajitsinji L. Rathod, P. Shrivastav, R. Shah

引用次数: 1

Anticancer properties of some triazolo[3,4-b][1,3,4]thiadiazoles 一些三唑[3,4-b][1,3,4]噻二唑的抗癌性质

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.4.001

I. Myrko, T. Chaban, Y. Horak, olodymyr Ogurtsov, I. Drapak, I. Chaban, V. Matiychuk

引用次数: 0

Pyrrole Based Schiff Base as a Highly Sensitive Fluorescent Sensor for Fe3+ and Sn2+ Ions 吡咯基席夫碱作为Fe3+和Sn2+离子的高灵敏度荧光传感器

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2022.12.003

D. Udhayakumari