Insecticidal efficacy and structure activity relationship study of some synthesized cyano-benzylidene and bisbenzylidene derivatives against Aphis nerii

Q2 Chemistry

Current Chemistry Letters Pub Date : 2023-01-01 DOI:10.5267/j.ccl.2023.3.003

M. El-Gaby, M. Bakry, Modather F. Hussein, Faraghally A. Faraghally, A. Khalil, Mohamed A Gad, A. Drar

引用次数: 2

Abstract

In this study, seven cyano-benzylidene and bisbenzylidene derivatives were designed and synthesized. All synthesized compounds were evaluated to determine their insecticidal activities as potential insecticides against nymphs and adults of Aphis nerii. These efforts led to the discovery of compounds 3a-d, 5, 7 and 10 with potent insecticidal activity (LC50 range from 0.0141 to 3.4351ppm). Compound 5 exhibited the highest insecticidal potency with 0.0141ppm. In addition, it indicated that compound 3b is less toxic than benzylidene and other precursors. Therefore, our results suggest that compound 5 has strong potential as a candidate component for developing a novel eco-friendly insecticide for control Aphids.

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合成的几种氰亚苄基和双亚苄基衍生物对灰蚜的杀虫效果及构效关系研究

本研究设计并合成了七种氰基苄基和双苄基衍生物。对所有合成的化合物进行了杀虫活性评价，测定了它们对灰蚜若虫和成虫的潜在杀虫活性。这些努力导致化合物3a-d, 5, 7和10具有有效的杀虫活性(LC50范围为0.0141至3.4351ppm)。化合物5的杀虫力最高，为0.0141ppm。此外，化合物3b的毒性低于苄基和其他前体。因此，我们的研究结果表明，化合物5作为一种新型的生态友好型杀虫剂具有很强的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Chemistry Letters Chemistry-Chemistry (all)

CiteScore

4.90

自引率

0.00%

发文量

审稿时长

20 weeks

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