Current Chemistry Letters最新文献_第2页

Batch and merging-zone flow injection methods for determination of tetracycline hydrochloride 间歇式和混区流动注射法测定盐酸四环素的含量

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.6.001

Esraa Rasool Radhi, K. Ali, Fatima Hydar Abdul Hussein

引用次数: 1

In vitro biological assessment of 1,3,4-oxadiazole sandwiched by azinane and acetamides supported by molecular docking and BSA binding studies 1,3,4-恶二唑夹氮烷和乙酰胺的体外生物学评价，分子对接和BSA结合研究

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2022.12.004

N. Virk, J. Iqbal, A. Aziz-ur-Rehman, M. Abbasi, S. Z. Siddiqui, S. Rasool, Mehr-un-Nisa Mehr-un-Nisa, M. Abid, H. Khalid, Fatiqa Zafar, Huraiza Javaid

{"title":"In vitro biological assessment of 1,3,4-oxadiazole sandwiched by azinane and acetamides supported by molecular docking and BSA binding studies","authors":"N. Virk, J. Iqbal, A. Aziz-ur-Rehman, M. Abbasi, S. Z. Siddiqui, S. Rasool, Mehr-un-Nisa Mehr-un-Nisa, M. Abid, H. Khalid, Fatiqa Zafar, Huraiza Javaid","doi":"10.5267/j.ccl.2022.12.004","DOIUrl":"https://doi.org/10.5267/j.ccl.2022.12.004","url":null,"abstract":"The 1,3,4-Oxadiazole is an aromatic heterocyclic moiety recognized in drug research for its low lipophilicity. The multiple functionalities, heterocyclic azinane, sulfonamide, 1,3,4-oxadiazole and acetamide, are combined collectively to enhance the bioactivity potential of synthesized molecules. All the compounds were acquired by following microwave assisted and conventional techniques in a comparative way. The synthesized derivatives were screened for their antibacterial and enzyme inhibition potential. Furthermore, BSA binding analysis was executed to infer about the interaction with serum albumin. The spectral data of IR, EI-MS, 1H-NMR and 13C-NMR were used to elucidate the final structures of compounds. The synthesized compounds had a modest antibacterial potential. Compound 8f bearing 2-methyl-4,5-dinitrophenyl group was the most active one against all the bacterial strains taken into account and α-glucosidase enzyme. Compound 8d bearing 4-nitrophenyl group was the best acetyl cholinesterase inhibitor and 8i bearing phenylethyl group was the best urease inhibitor.","PeriodicalId":10942,"journal":{"name":"Current Chemistry Letters","volume":"181 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72541166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metal contents of some selected vegetables grown in Bodoland territorial region of Assam, India 在印度阿萨姆邦博多兰地区种植的一些选定蔬菜的金属含量

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.3.009

Bimal Boro, Sanjay Basumatary, B. Das

{"title":"Metal contents of some selected vegetables grown in Bodoland territorial region of Assam, India","authors":"Bimal Boro, Sanjay Basumatary, B. Das","doi":"10.5267/j.ccl.2023.3.009","DOIUrl":"https://doi.org/10.5267/j.ccl.2023.3.009","url":null,"abstract":"Metals play a crucial role in the metabolic pathways during the growth of vegetable plants. The presence of heavy metals or trace metals also takes a vital role in the nutrient quality of a vegetable. The vegetables are an inevitable part of the human diet and provide essential nutrients to maintain the normal functioning of human health and growth. The application of fertilizers and pesticides facilitates the accumulation of heavy metals by the vegetables grown in the fields. Consumption of heavy metals beyond the permissible limit along with vegetables may impact human health. Moreover, the production of nutritious food and its safety is an important aspect of the measure of any nation’s economy. Considering all these points, the present work was undertaken to analyze the heavy metal contents in the six mostly produced and consumed vegetables grown in Bodoland Territorial Region (BTR), a tribal-dominated region of the state Assam, India. The vegetables analyzed were fern leaves (Diplazium esculentum), jute leaves (Corchorus olitorius), green arum leaves (Colocasia esculenta), pointed gourd (Trichosanthes dioica), yard long bean (Vigna unguiculata ssp. Sesquipedalis) and spiny gourd (Momordica dioica). The metals analyzed were Cu, Fe, Ni, and Zn. The presence of heavy metals was detected in all the vegetable samples.","PeriodicalId":10942,"journal":{"name":"Current Chemistry Letters","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85212012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of phthalimide and naphthalimide derived Biginelli compounds and evaluation of their anti-inflammatory and anti-oxidant activities 邻苯二胺及萘酰亚胺衍生物Biginelli化合物的合成及其抗炎抗氧化活性评价

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.1.004

Pradeep Rameshrao Totawar, Dr. Ravi Varala, Vijay Kotra, J. Pulle

引用次数: 2

Toxicity assessment of certain insecticides on the red soft scale insect, Pulvinaria tenuivalvata (Newstead) infesting sugarcane plants 某些杀虫剂对甘蔗红软蚧虫毒力评价

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2022.11.002

M. Bakry, A. Badawy, L. Mohamed

引用次数: 0

Synthesis, spectroscopic characterization and biological activities of some metal complexes with new heterocyclic azodye ligand 2-(2-hydroxynaphthalen-1-yl azo)-pyridin-3-ol 新型杂环偶氮染料配体2-(2-羟基萘-1-酰基偶氮)-吡啶-3-醇金属配合物的合成、光谱表征及生物活性

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2022.9.006

V. Vidya, V. Sadasivan

{"title":"Synthesis, spectroscopic characterization and biological activities of some metal complexes with new heterocyclic azodye ligand 2-(2-hydroxynaphthalen-1-yl azo)-pyridin-3-ol","authors":"V. Vidya, V. Sadasivan","doi":"10.5267/j.ccl.2022.9.006","DOIUrl":"https://doi.org/10.5267/j.ccl.2022.9.006","url":null,"abstract":"Metal complexes of [2-(2-hydroxynaphthalen-1-ylazo)-pyridin-3-ol] are derived from 2-amino-3-hydroxypyridine and β-naphthol was synthesized and characterized by thermal, spectral and analytical tools. The ligand was reacted with Mn(II), Fe(II), Co(II), Ni(II), Cu(II) and Zn(II) in 1:2 stoichiometry. The IR spectra confirms the azo ligand coordination to metal ions via azo nitrogen and phenolic oxygen of pyridine after deprotonation. Both IR and 1HNMR spectra recorded involvement of deprotonated hydroxyl groups with proton displacement. The magnified fluorescence was shown by Mn(II) and Ni(II) complexes. None of the prepared ligands or complexes show any NLO activity with KDP as standard. The DNA cleavage and anticancerous activities done. The influence of zinc chelates on cure characteristics of rubber compounds was estimated based on rheometer measurements. The ligand and metal complexes are tested in vitro against some bacteria and fungi species. The antioxidant activities, DNA cleavage and anticancerous activities done. Ligand and its complexes catalysed cleavage of DNA.","PeriodicalId":10942,"journal":{"name":"Current Chemistry Letters","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85944237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Studies on Nile river pollution and water quality indicators in Egypt 埃及尼罗河污染及水质指标研究

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2022.8.009

Ahmed M. K. Abouhalima, Liang Yingxia

引用次数: 0

Sorption characteristics and thermodynamic parameters of bispyribac-sodium and metribuzin on alluvial soil with difference in particle size and pH value 不同粒径和pH值下双嘧菌酯钠和甲霉嗪在冲积土上的吸附特性及热力学参数

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.3.001

Mohamed R. Fouad, A. F. El-Aswad, M. Aly, Mohamed Alfateh Badawy

{"title":"Sorption characteristics and thermodynamic parameters of bispyribac-sodium and metribuzin on alluvial soil with difference in particle size and pH value","authors":"Mohamed R. Fouad, A. F. El-Aswad, M. Aly, Mohamed Alfateh Badawy","doi":"10.5267/j.ccl.2023.3.001","DOIUrl":"https://doi.org/10.5267/j.ccl.2023.3.001","url":null,"abstract":"The behavior of bispyribac-sodium and metribuzin herbicides was investigated into alluvial soil. Effect of pH, temperature, and particle size of soil on the sorption process was studied. Sorption isotherms by bulk soil and its sand, silt, clay and humic acid (HA) fractions were quantified using the batch equilibration technique. The results showed that sorption of herbicides tested was significantly affected by temperature and was a spontaneous interfacial process into soil. Freundlich equation accurately predicted the sorption behavior of two herbicides. Thermodynamic parameters summarized that the negative values of the standard free energy changes (ΔG˚) were obtained therefore, the adsorption of tested pesticides in soil was spontaneous and small negative values indicate the sorption is physical in nature involving weak forces of attraction. The negative ΔH˚ value, indicating metribuzin and bispyribac-sodium interactions are exothermic processes and products are energetically stable with a high binding of compound to soil sites. There was an increase in the entropy of tested pesticides-soil systems as shown by positive values of ΔS˚. The highest adsorption in soil was at pH 5 for bispyribac-sodium and at pH 7 for metribuzin. The sorption of metribuzin and bispyribac-sodium were significantly greater on HA fraction followed by clay fraction than the bulk soil. The KF and Kd values increase with decreasing particle size particularly in the case of adsorption of metribuzin.","PeriodicalId":10942,"journal":{"name":"Current Chemistry Letters","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90432436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Synthesis of novel pyrazolic analogues of chalcones as potential antibacterial and antifungal agents 新型吡唑类查尔酮潜在抗菌抗真菌药物的合成

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2023.2.001

C. Kumar, S. Manjunatha, B. Nandeshwarappa

引用次数: 0

Synthesis and catalytic activity of Cu (II) complex with 4-phenyl 2, 6-di (thiazol-2-yl) pyridine in the oxidation of para-aminophenol Cu (II)与4-苯基2,6 -二(噻唑-2-基)吡啶配合物氧化对氨基苯酚的合成及催化活性研究

Current Chemistry Letters Pub Date : 2023-01-01 DOI: 10.5267/j.ccl.2022.8.005

A. Goel, M. Rani

{"title":"Synthesis and catalytic activity of Cu (II) complex with 4-phenyl 2, 6-di (thiazol-2-yl) pyridine in the oxidation of para-aminophenol","authors":"A. Goel, M. Rani","doi":"10.5267/j.ccl.2022.8.005","DOIUrl":"https://doi.org/10.5267/j.ccl.2022.8.005","url":null,"abstract":"In the present work the synthesis of 4-phenyl-2, 6-di (thiazol-2-yl) pyridine copper chloride (abbreviated as Cu-DTPy) complex using copper (II) chloride and 2, 6-di (thiazol-2-yl) pyridine has been carried out. The complex has been specified by UV-Vis, FT-IR, CHNS and ESI-MS methods of analysis. The synthesized copper complex has been used as catalyst in the oxidation of p-aminophenol using hexacyanoferrate (III) ions as an oxidant in aqueous alkaline medium by kinetic-spectrophotometric method. This experimental work was carried out at optimum pH 11.0 and temperature 25ºC. The variation of effect of concentration of p-aminophenol (abbreviated as PAP), hexacyanoferrate (III) ions, and Cu-DTPy catalyst on reaction rate has been studied. Thermodynamic parameters such as free energy of activation, activation energy, enthalpy and frequency factor have been evaluated with the change in rate of the reaction at four disparate temperatures i.e. 25-40ᵒC. The oxidation products have been identified by FT-IR and ESI-MS spectroscopic analytical techniques. The major product of this reaction is NN’-bis-(p-hydroxyphenyl)-2-hydroxy-5-amino-1,4-benzoquinone di-imine. Thus, this method is highly efficient and environmentally safe to remove PAP from polluted water resources.","PeriodicalId":10942,"journal":{"name":"Current Chemistry Letters","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83875617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0