Silica-zinc chloride (SiO2-ZnCl2) catalyzed Michael addition reaction of active methylene compounds to β-nitrostyrenes: Synthesis of functionalized pyrazole derivatives

Q2 Chemistry

Current Chemistry Letters Pub Date : 2023-01-01 DOI:10.5267/j.ccl.2022.10.001

V. Krishnan, Santha Kumari Merugu, V. K. Reddy, H. Bollikolla

引用次数: 0

Abstract

Under solvent-free conditions, a simple and efficient procedure has been developed for the Michael addition reaction of active methylene compounds to β-nitrostyrenes. The resulting Michael adducts are efficiently converted into functionalized pyrazole derivatives with hydrazine hydrate in excellent yields. All the compounds were well characterized by spectroscopic techniques.

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二氧化硅-氯化锌(SiO2-ZnCl2)催化活性亚甲基化合物与β-硝基苯乙烯的Michael加成反应:功能化吡唑衍生物的合成

在无溶剂条件下，建立了一种简单有效的活性亚甲基化合物与β-亚硝基苯乙烯的Michael加成反应。得到的Michael加合物与水合肼有效地转化为功能化吡唑衍生物，收率高。所有化合物都用光谱技术进行了很好的表征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Chemistry Letters Chemistry-Chemistry (all)

CiteScore

4.90

自引率

0.00%

发文量

审稿时长

20 weeks

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