Current opinion in microbiology最新文献_第3页

The cell envelope of diderm bacteria: a unified scaffold, not a stack of layers diderm细菌的细胞包膜：一个统一的支架，而不是一层一层的堆叠

IF 7.5 2区生物学

Current opinion in microbiology Pub Date : 2025-12-01 Epub Date: 2025-11-07 DOI: 10.1016/j.mib.2025.102681

Michaël Deghelt , Elisa S. Pierre Despas , Jean-François Collet

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引用次数: 0

Applicability of synthetic communities of the infant gut microbiota to understand microbial dynamics in an interchanging glycan landscape 婴儿肠道微生物群的合成群落的适用性，以了解相互交换的聚糖景观中的微生物动力学

IF 7.5 2区生物学

Current opinion in microbiology Pub Date : 2025-12-01 Epub Date: 2025-08-30 DOI: 10.1016/j.mib.2025.102659

Athanasia Ioannou, Clara Belzer

引用次数: 0

The role of mobile genetic elements in adaptation of the microbiota to the dynamic human gut ecosystem 移动遗传因子在微生物群适应动态人类肠道生态系统中的作用

IF 7.5 2区生物学

Current opinion in microbiology Pub Date : 2025-12-01 Epub Date: 2025-09-27 DOI: 10.1016/j.mib.2025.102675

Katherine Schubert, Teni Shosanya, Leonor García-Bayona

引用次数: 0

Trace gas oxidation as a novel microbial dispersal trait 微量气体氧化是一种新的微生物扩散特性

IF 7.5 2区生物学

Current opinion in microbiology Pub Date : 2025-12-01 Epub Date: 2025-09-10 DOI: 10.1016/j.mib.2025.102666

Lucas Barbieri Oliveri , Pok Man Leung

引用次数: 0

Circadian interactions between plants and microorganisms 植物和微生物之间的昼夜相互作用

IF 7.5 2区生物学

Current opinion in microbiology Pub Date : 2025-12-01 Epub Date: 2025-08-15 DOI: 10.1016/j.mib.2025.102655

Jack Dorling, Georgia Love, Isobel K. Banks, Antony N. Dodd

{"title":"Circadian interactions between plants and microorganisms","authors":"Jack Dorling, Georgia Love, Isobel K. Banks, Antony N. Dodd","doi":"10.1016/j.mib.2025.102655","DOIUrl":"10.1016/j.mib.2025.102655","url":null,"abstract":"<div><div>Life on Earth evolved in environmental conditions that fluctuate with a daily cycle. Organisms from all kingdoms of life, including plants and their associated microorganisms, harbour circadian clocks as an adaptation to these environmental changes. We review the involvement of circadian clocks in associations between plants and microbes, focusing first on mechanisms of specific circadian clock-regulated plant–microbe interactions. We then discuss more general ecological and evolutionary consequences of clock regulation of plant–microbe interactions and argue that circadian clocks can choreograph complex plant–microbe community interactions across multiple levels of biological organisation. We also discuss the difficulties in determining the precise nature of interactions in such communities, for both individual rhythmic interactions and the emergent rhythmic properties of these communities. An understanding of the regulation of these interactions by circadian clocks is likely to have implications for crop performance, fertiliser and pesticide use, soil and ecosystem health, biogeochemical cycling, and the impacts of global warming.</div></div>","PeriodicalId":10921,"journal":{"name":"Current opinion in microbiology","volume":"88 ","pages":"Article 102655"},"PeriodicalIF":7.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144841909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diversity and evolution of alphaproteobacterial dimorphism α变形菌二态性的多样性和进化

IF 7.5 2区生物学

Current opinion in microbiology Pub Date : 2025-12-01 Epub Date: 2025-09-09 DOI: 10.1016/j.mib.2025.102661

Joel Hallgren , Kristina Jonas

{"title":"Diversity and evolution of alphaproteobacterial dimorphism","authors":"Joel Hallgren , Kristina Jonas","doi":"10.1016/j.mib.2025.102661","DOIUrl":"10.1016/j.mib.2025.102661","url":null,"abstract":"<div><div>Many bacteria have complex pleomorphic lifecycles — a feature particularly widespread across the class <em>Alphaproteobacteria</em> of the phylum <em>Pseudomonadota</em>. While research on bacteria with pleomorphic lifecycles has for many years focused on the dimorphic bacterium <em>Caulobacter crescentus</em>, more recent studies on less established alphaproteobacterial model bacteria have uncovered diverse variations of bacterial pleomorphism. Here, we provide an overview of the diversity and evolution of the complex lifecycles among dimorphic <em>Alphaproteobacteria</em> and highlight the presence of analogous lifecycles in unrelated bacteria across the bacterial domain. We discuss the commonalities and differences between dimorphic species, as well as the selective pressures that might have sculpted their lifecycles. Furthermore, we exemplify how the cellular appendages common among dimorphic <em>Alphaproteobacteria</em>, referred to as prosthecae, are not inherently linked to dimorphism. Finally, we highlight how the large diversity of dimorphic <em>Alphaproteobacteria</em> can be used to shed light onto the evolution of bacterial cell biology.</div></div>","PeriodicalId":10921,"journal":{"name":"Current opinion in microbiology","volume":"88 ","pages":"Article 102661"},"PeriodicalIF":7.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial overview: Antibiotic discovery: Feeding the pipeline or finding new pipes? 编辑概述：抗生素的发现：喂养管道还是寻找新的管道？

IF 7.5 2区生物学

Current opinion in microbiology Pub Date : 2025-12-01 Epub Date: 2025-11-01 DOI: 10.1016/j.mib.2025.102680

Joshua AV Blodgett , Justin R Nodwell

引用次数: 0

Microbial biomolecular condensates: from conserved principles to synthetic biology opportunities 微生物分子凝聚物：从保守原理到合成生物学的机会。

IF 7.5 2区生物学

Current opinion in microbiology Pub Date : 2025-12-01 Epub Date: 2025-10-13 DOI: 10.1016/j.mib.2025.102677

Donté A Stevens, Keren Lasker

引用次数: 0

Decoding the epigenetic blueprint behind Toxoplasma (pre)sexual commitment and chronic persistence 破译弓形虫（前）性承诺和慢性持久性背后的表观遗传蓝图

IF 7.5 2区生物学

Current opinion in microbiology Pub Date : 2025-12-01 Epub Date: 2025-08-30 DOI: 10.1016/j.mib.2025.102662

Martina Shahinas, Belen Pachano, Marie G Robert, Christopher Swale, Mohamed-Ali Hakimi

{"title":"Decoding the epigenetic blueprint behind Toxoplasma (pre)sexual commitment and chronic persistence","authors":"Martina Shahinas, Belen Pachano, Marie G Robert, Christopher Swale, Mohamed-Ali Hakimi","doi":"10.1016/j.mib.2025.102662","DOIUrl":"10.1016/j.mib.2025.102662","url":null,"abstract":"<div><div><em>Toxoplasma gondii</em>, a widespread apicomplexan parasite, navigates a complex life cycle in which it switches back and forth between tachyzoites and bradyzoites to balance acute infection and persistence while also undergoing an often-overlooked one-way commitment to the sexual stage. Emerging evidence suggests that <em>Toxoplasma</em>’s developmental trajectories are orchestrated by an interconnected network of transcriptional switches and chromatin remodeling mechanisms, acting in concert to ensure robust stage transitions. This review outlines an updated epigenetic framework for stage transitions and highlights the functional synergy between an Imitation SWItch family chromatin remodeler and the MORC/HDAC3 repressor complex, which together modulate chromatin accessibility to maintain or shift developmental states. We also spotlight recent findings, showing that simultaneous depletion of AP2XII-1 and AP2XI-2 transcription factors reactivates the presexual program <em>in vitro</em>, eliminating the need for cat hosts and allowing ethical, scalable exploration of sexual stages. Strikingly, the knockdown of these transcription factors also reveals a previously unrecognized hybrid zoite co-expressing bradyzoite and merozoite markers, suggesting a transitional state that defies classical stage definition. This hybrid form, as well as more recent data on bradyzoite development, support a new model in which <em>T. gondii</em> development unfolds along a continuum of epigenetically primed states rather than a rigid sequence of binary fate decisions. These findings provide a powerful conceptual and experimental framework for dissecting parasite transmission and persistence and have far-reaching implications for the biology of other parasites in the phylum.</div></div>","PeriodicalId":10921,"journal":{"name":"Current opinion in microbiology","volume":"88 ","pages":"Article 102662"},"PeriodicalIF":7.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subcellular organization of the archaeal cell 古细菌细胞的亚细胞组织。

IF 7.5 2区生物学

Current opinion in microbiology Pub Date : 2025-12-01 Epub Date: 2025-10-29 DOI: 10.1016/j.mib.2025.102679

Arthur Charles-Orszag , Sonja-Verena Albers

引用次数: 0