Current diabetes reviews最新文献_第7页

Novel Approaches to Control Diabetes. 控制糖尿病的新方法。

IF 3.3

Current diabetes reviews Pub Date : 2024-01-01 DOI: 10.2174/1573399820666230809152742

Malissa Mathew Dmello, Geeta Bhagwat

引用次数: 0

Potential use of Acrocomia aculeata Pulp Oil in the Modulation of Chronic Non-communicable Diseases, Especially in Diabetes: A Systematic Review. Acrocomia aculeata果肉油在调节慢性非传染性疾病，尤其是糖尿病方面的潜在用途：系统综述。

IF 3.3

Current diabetes reviews Pub Date : 2024-01-01 DOI: 10.2174/1573399820666230913105935

Maurílio de Souza Cazarim, Davi Trombini Aleixo, Estael Luzia Coelho da Cruz-Cazarim, Mohamed A Abd El-Salam, Frederico Pittella

{"title":"Potential use of Acrocomia aculeata Pulp Oil in the Modulation of Chronic Non-communicable Diseases, Especially in Diabetes: A Systematic Review.","authors":"Maurílio de Souza Cazarim, Davi Trombini Aleixo, Estael Luzia Coelho da Cruz-Cazarim, Mohamed A Abd El-Salam, Frederico Pittella","doi":"10.2174/1573399820666230913105935","DOIUrl":"10.2174/1573399820666230913105935","url":null,"abstract":"Introduction: The fruit oil from Acrocomia aculeata (Macauba or Bocaiuva) is highly rich in antioxidants and other bioactive compounds, emerging as a natural source of high potential for the modulation of chronic non-communicable diseases (NCDs), like diabetes. Its effects on chronic NCDs are poorly studied yet. This review aimed to evaluate the therapeutic results of pharmaceutical preparations containing Acrocomia aculeata pulp oil that are used for chronic NCDs.Method: A search was performed using PICO acronyms in English, Portuguese, and Spanish languages in the MEDLINE®, PubMed, EMBASE, Scopus, LILACs, and CENTRAL Cochrane Library databases. The degree of agreement for selection and eligibility was significant (Kappa= 0.992; 95% CI: 0.988-0.996). The difference between the intervention and control groups for blood glucose reduction was 63.5 ± 69.5 mg/dL (p<0.0001).Result: Overall, an improvement percentage of 55.1 ± 0.1 was observed for the variables associated with chronic NCDs, which represented 89.96% of the relative risk reduction (efficacy).Conclusion: The Acrocomia aculeate pulp oil exhibited promising results in experimental studies for glycemic control and reduction of a specific tumor, indicating a good potential to be explored for chronic NCDs treatment.","PeriodicalId":10825,"journal":{"name":"Current diabetes reviews","volume":" ","pages":"e130923221014"},"PeriodicalIF":3.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10247091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Insight of Naturally Occurring Phytoconstituents and Novel Approaches Towards the Treatment of Diabetes. 洞察天然植物成分和治疗糖尿病的新方法。

IF 3.3

Current diabetes reviews Pub Date : 2024-01-01 DOI: 10.2174/1573399820666230829094724

Zulfa Nooreen, Awani Kumar Rai, Fariha Summayya, Sudeep Tandon

{"title":"An Insight of Naturally Occurring Phytoconstituents and Novel Approaches Towards the Treatment of Diabetes.","authors":"Zulfa Nooreen, Awani Kumar Rai, Fariha Summayya, Sudeep Tandon","doi":"10.2174/1573399820666230829094724","DOIUrl":"10.2174/1573399820666230829094724","url":null,"abstract":"Background: The rising in diabetes incidents has clearly become one main worldwide health problem. Individuals suffering from diabetes are still more susceptible to many long-term and short-term side effects, which most often cause fatalities. Even though chemically synthesized anti-diabetic entities are capable of helping manage and treat, there has been significant risks related with their prolong and repetitive use. Hence, there is a requirement for safer and novel approaches that might be formed and utilized.Objective: Aim of the present review is to explain the naturally occurring phytochemicals and novel approach as anti-diabetic agents in the treatment of diabetes and its related issues.Method: A survey of Google scholar, Research Gate, Pubmed, Science Direct, NCBI database was carried out conducted to determine a most hopeful phytochemicals and novel drug delivery systems in the management of diabetes.Result: The study stressed the significance of phytomolecules and some novel approaches researched or reported in the literature for the management and cure of diabetes. It is suggested that changes in lifestyle can help patients and like nutritional support, assessment and lifestyle guidance must be individualized based on physical and functional capacity. Further evaluations and improved preventative medicine were the result of improving patient outcomes.Conclusion: Conventional or synthetic drugs provide relief for short time but nanoformulations of phytomolecules offer an improved therapeutic with fewer negative side effects. Herbal medicines are rich in phytoconstituents and possess variety of health benefits. This review is compilation of phytoconstituents and novel drug delivery system of phytomolecules i.e. nanoparticles, niosomes, microsphere, microparticle and others.","PeriodicalId":10825,"journal":{"name":"Current diabetes reviews","volume":" ","pages":"e290823220456"},"PeriodicalIF":3.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10113284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insulin Glargine in Type 1 Diabetes Mellitus: A Review of Clinical Trials and Real-world Evidence Across Two Decades. 格列奈胰岛素治疗 1 型糖尿病：回顾二十年来的临床试验和现实世界的证据。

IF 3.3

Current diabetes reviews Pub Date : 2024-01-01 DOI: 10.2174/1573399819666230310150905

Banshi Saboo, Hemraj Chandalia, Sujoy Ghosh, Jothydev Kesavadev, I P S Kochar, K M Prasannakumar, Archana Sarda, Ganapathi Bantwal, R N Mehrotra, Madhukar Rai

{"title":"Insulin Glargine in Type 1 Diabetes Mellitus: A Review of Clinical Trials and Real-world Evidence Across Two Decades.","authors":"Banshi Saboo, Hemraj Chandalia, Sujoy Ghosh, Jothydev Kesavadev, I P S Kochar, K M Prasannakumar, Archana Sarda, Ganapathi Bantwal, R N Mehrotra, Madhukar Rai","doi":"10.2174/1573399819666230310150905","DOIUrl":"10.2174/1573399819666230310150905","url":null,"abstract":"Background: Over the past two decades, insulin glargine 100 U/mL (Gla-100) has emerged as the \"standard of care\" basal insulin for the management of type 1 diabetes mellitus (T1DM). Both formulations, insulin glargine 100 U/mL (Gla-100) and glargine 300 U/mL (Gla- 300) have been extensively studied against various comparator basal insulins across various clinical and real-world studies. In this comprehensive article, we reviewed the evidence on both insulin glargine formulations in T1DM across clinical trials and real-world studies.Methods: Evidence in T1DM for Gla-100 and Gla-300 since their approvals in 2000 and 2015, respectively, were reviewed.Results: Gla-100 when compared to the second-generation basal insulins, Gla-300 and IDeg-100, demonstrated a comparable risk of overall hypoglycemia, but the risk of nocturnal hypoglycemia was higher with Gla-100. Additional benefits of Gla-300 over Gla-100 include a prolonged (>24- hours) duration of action, a more stable glucose-lowering profile, improved treatment satisfaction, and greater flexibility in the dose administration timing.Conclusion: Both glargine formulations are largely comparable to other basal insulins in terms of glucose-lowering properties in T1DM. Further, risk of hypoglycemia is lower with Gla-100 than Neutral Protamine Hagedorn but comparable to insulin detemir.","PeriodicalId":10825,"journal":{"name":"Current diabetes reviews","volume":" ","pages":"e100323214554"},"PeriodicalIF":3.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10909813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9076588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioactive Vitamins and Epigenetic Modifications in Diabetes: A Perspective. 糖尿病中的生物活性维生素和表观遗传修饰：透视。

IF 3.3

Current diabetes reviews Pub Date : 2024-01-01 DOI: 10.2174/1573399819666230330124035

Mihnea-Alexandru Găman, Elena-Codruța Cozma, Bahadar S Srichawla, Matei-Alexandru Cozma, Hamed Kord Varkaneh, Yongfeng Chen, Amelia Maria Găman, Camelia Cristina Diaconu

引用次数: 0

Effect of Ankle Brachial Index (ABI) and Compression Therapy on Diabetic Foot Ulcer Healing. 踝臂指数（ABI）和加压疗法对糖尿病足溃疡愈合的影响

IF 3.3

Current diabetes reviews Pub Date : 2024-01-01 DOI: 10.2174/1573399819666230331083420

Asmat Burhan, Fitri Arofiati, Vanessa Abreu Da Silva, Septian Mixrova Sebayang

{"title":"Effect of Ankle Brachial Index (ABI) and Compression Therapy on Diabetic Foot Ulcer Healing.","authors":"Asmat Burhan, Fitri Arofiati, Vanessa Abreu Da Silva, Septian Mixrova Sebayang","doi":"10.2174/1573399819666230331083420","DOIUrl":"10.2174/1573399819666230331083420","url":null,"abstract":"Purpose: Knowing the effect of compression therapy on the value of the Ankle Brachial Index in the healing process of Diabetic Foot Ulcer.Design: This study used a quasi-experimental method with pretest-posttest with control group design with purposive sampling and non-equivalent control groups for eight weeks of treatment.Subjects and setting: Patients diagnosed with Diabetic Foot Ulcer have and have Peripheral Artery Disease, patient characteristics are homogenized, age >18 years, wound care every three days, Ankle Brachial Index values between 0.6-1.3 mmHg, research three clinics in Indonesia in February 2021.Methods: The population with Diabetic Foot Ulcer was screened by inclusion criteria with Ankle Brachial Index and Bates-Jensen Wound Assessment Tool instruments, a total of n=140; in the study, thirteen samples were excluded, the intervention group was given Compression Therapy n= 68, and the control group was compression stockings for eight weeks n=59, the data were statistically analyzed non-parametric test using Wilcoxon and Mann-Whitney U.Results: Statistical analysis showed that the mean difference in paired group means was 26.4%. Meanwhile, in the mean analysis, the difference in the post-test healing of diabetic foot ulcers was 2.83%; p=0.000 and improvement of peripheral microcirculation was 33.02%; p=0.000 in the eighth week. Thus, compression therapy intervention in diabetic foot ulcer patients can improve peripheral microcirculation and increase Diabetic Foot Ulcers healing compared to the control group.Conclusion: Compression therapy tailored to the patient's needs and according to standard operating procedures can improve peripheral microcirculation, so that blood flow in the legs becomes normal; it can speed up the healing process of Diabetic Foot Ulcers.","PeriodicalId":10825,"journal":{"name":"Current diabetes reviews","volume":" ","pages":"e310323215277"},"PeriodicalIF":3.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9603386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diabetic Retinopathy: Clinical Features, Risk Factors, and Treatment Options. 糖尿病视网膜病变：临床特征、危险因素和治疗选择。

IF 3.3

Current diabetes reviews Pub Date : 2024-01-01 DOI: 10.2174/0115733998252551231018080419

Sudhanshu Mishra, Pratik Kumar Vishwakarma, Mridani Tripathi, Smriti Ojha, Shivendra Mani Tripathi

{"title":"Diabetic Retinopathy: Clinical Features, Risk Factors, and Treatment Options.","authors":"Sudhanshu Mishra, Pratik Kumar Vishwakarma, Mridani Tripathi, Smriti Ojha, Shivendra Mani Tripathi","doi":"10.2174/0115733998252551231018080419","DOIUrl":"10.2174/0115733998252551231018080419","url":null,"abstract":"Diabetic retinopathy is a common complication of diabetes that affects the eyes and can lead to severe vision loss or blindness if left untreated. Chronic hyperglycemia destroys the blood vessels in the retina, resulting in diabetic retinopathy. The damage can lead to leakage of fluid and blood into the retina, causing edema, hemorrhages, and ischemia. A thorough evaluation by an ophthalmologist is necessary to determine the most appropriate course of treatment for each patient with diabetic retinopathy. The article discusses various surgical treatment options for diabetic retinopathy, including vitrectomy, scleral buckling, epiretinal membrane peeling, retinal detachment repair, and the risk factors of diabetic retinopathy. These surgical techniques can help to address the underlying causes of vision loss and prevent further complications from developing or worsening. To avoid complications and maintain vision, this review emphasizes the significance of early detection and treatment of diabetic retinopathy. Patients with diabetic retinopathy can improve their eyesight and quality of life with the help of some surgical treatments. The article also highlights some case studies in the field of diabetic retinopathy.","PeriodicalId":10825,"journal":{"name":"Current diabetes reviews","volume":" ","pages":"e271023222871"},"PeriodicalIF":3.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71479137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overview of Natural Supplements for the Management of Diabetes and Obesity. 用于治疗糖尿病和肥胖症的天然补充剂概述。

IF 3.3

Current diabetes reviews Pub Date : 2024-01-01 DOI: 10.2174/0115733998262859231020071715

Sonia Singh, Arpit Shukla, Shiwangi Sharma

引用次数: 0

Current Landscape of Various Techniques and Methods of Gene Therapy through CRISPR Cas9 along with its Pharmacological and Interventional Therapies in the Treatment of Type 2 Diabetes Mellitus. 通过CRISPR-Cas9进行基因治疗的各种技术和方法及其在治疗2型糖尿病中的药理学和介入治疗的现状。

IF 3.3

Current diabetes reviews Pub Date : 2024-01-01 DOI: 10.2174/0115733998263079231011073803

Pranay Wal, Namra Aziz, Harshit Prajapati, Shashank Soni, Ankita Wal

{"title":"Current Landscape of Various Techniques and Methods of Gene Therapy through CRISPR Cas9 along with its Pharmacological and Interventional Therapies in the Treatment of Type 2 Diabetes Mellitus.","authors":"Pranay Wal, Namra Aziz, Harshit Prajapati, Shashank Soni, Ankita Wal","doi":"10.2174/0115733998263079231011073803","DOIUrl":"10.2174/0115733998263079231011073803","url":null,"abstract":"Background: Type 2 diabetes mellitus (T2DM) is frequently referred to as a \"lifestyle illness\". In 2000, India (31.7 million) had the greatest global prevalence of diabetes mellitus, followed by China (20.8 million), the United States (17.7 million), and other countries. In recent years, the treatment of gene therapy (T2DM) has attracted intensive interest.Objective: We aimed to critically review the literature on the various techniques and methods, which may be a possible novel approach through the gene therapy CRISPR Cas9 and some other gene editing techniques for T2DM. Interventional and pharmacological approaches for the treatment of T2DM were also included to identify novel therapies for its treatment.Method: An extensive literature survey was done on databases like PubMed, Elsevier, Science Direct and Springer.Conclusion: It can be concluded from the study that recent advancements in gene-editing technologies, such as CRISPR Cas9, have opened new avenues for the development of novel therapeutic approaches for T2DM. CRISPR Cas9 is a powerful tool that enables precise and targeted modifications of the genome.","PeriodicalId":10825,"journal":{"name":"Current diabetes reviews","volume":" ","pages":"e201023222414"},"PeriodicalIF":3.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49689152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Glp-1 Mimetics and Autophagy in Diabetic Milieu: State-of-the-Art. 糖尿病环境中的 Glp-1 拟效物与自噬：最新技术。

IF 2.4

Current diabetes reviews Pub Date : 2024-01-01 DOI: 10.2174/0115733998276570231222105959

Habib Yaribeygi, Mina Maleki, Raul D Santos, Tannaz Jamialahmadi, Amirhossein Sahebkar

引用次数: 0