Current Directions in Biomedical Engineering最新文献_第9页

Towards AI-driven minimally invasive needle interventions 走向人工智能驱动的微创针头干预

Current Directions in Biomedical Engineering Pub Date : 2023-09-01 DOI: 10.1515/cdbme-2023-1140

Moritz Spiller, Nazila Esmaeili, Thomas Sühn, Axel Boese, Michael Friebe, Alfredo Illanes, Salmai Turial

引用次数: 0

Digital personalized medical insole process 数字化个性化医疗鞋垫工艺

Current Directions in Biomedical Engineering Pub Date : 2023-09-01 DOI: 10.1515/cdbme-2023-1008

Diana Völz, Julia Schneider, Ulrich Wuttke

{"title":"Digital personalized medical insole process","authors":"Diana Völz, Julia Schneider, Ulrich Wuttke","doi":"10.1515/cdbme-2023-1008","DOIUrl":"https://doi.org/10.1515/cdbme-2023-1008","url":null,"abstract":"Abstract Medical insoles are used to correct patient’s foot malpositions or to relieve certain foot areas from pressure. The required insole type depends largely on the presenting clinical picture and the individual’s needs. Accurate fit of medical insoles is critical to wearer acceptance, which is a necessary precondition where further serious injury is to be prevented. An end-to-end digital process offers the potential to better adapt insoles to the personalized patients’ foot geometry and pressure load. Furthermore, the whole gait-cycle could be included in the digitalization process and the adaption could consider special needs of different gait phases. This hasn’t been done, yet. For this purpose, a digital process chain was developed and prototypically tested in collaboration with an orthopaedist. 3D scans of the foot geometry in various loaded conditions were compiled and the corresponding gait analysis images were mapped. Both results were overlaid in a CAD program to create a model and identify the clinical picture. Adapted to the geometry of the foot, a volumetric model of the medical insole was built, individual stress zones were separated and filled with lattice structures of different parameters. The insole was 3D printed. The results of the present examination show benefits in using the loaded foot scan to model insoles, as malpositions can be checked automatically via standard (digital) tests. While it is possible to model and print medical insoles in one piece with differing strengths, there is limited information about the influence of the designed lattice structure on a specific printing result (i. e. the material behaviour).","PeriodicalId":10739,"journal":{"name":"Current Directions in Biomedical Engineering","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135394987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The potential role of 3D-printed phantoms in quality control of artificial intelligence-based algorithms in medical imaging 3d打印幻影在医疗成像中基于人工智能算法的质量控制中的潜在作用

Current Directions in Biomedical Engineering Pub Date : 2023-09-01 DOI: 10.1515/cdbme-2023-1074

Ali Pashazadeh, Christoph Hoeschen

{"title":"The potential role of 3D-printed phantoms in quality control of artificial intelligence-based algorithms in medical imaging","authors":"Ali Pashazadeh, Christoph Hoeschen","doi":"10.1515/cdbme-2023-1074","DOIUrl":"https://doi.org/10.1515/cdbme-2023-1074","url":null,"abstract":"Abstract To ensure accurate and consistent imaging of patients, medical imaging systems are controlled and tested using phantoms. Despite the availability of commercial standard phantoms for decades, 3D printing technology has gained special attention as a tool for producing accurate and costeffective tissue-mimicking phantoms. As artificial intelligence (AI) becomes increasingly prevalent in medical imaging, dedicated phantoms are needed for testing their reliability, robustness, and quality before they are implemented in clinical settings. In this context, 3D-printed imaging phantoms, which have specific requirements relevant to AI models, can play a crucial role. Due to its unique ability to create phantoms of almost any complexity, 3D printing technology seems a suitable approach for the quality control of AI models in medical imaging. The following reviews some of the works that used 3D-printed technology to create custom-built phantoms for use in Computed Tomography (CT), nuclear imaging, Magnetic Resonance Imaging (MRI), and ultrasound imaging. The focus of this short review is on the accuracy of 3D-printed technology in creating imaging phantoms. In the end, the potential of the 3D-printed phantoms in testing and quality control of AI-based algorithms in radiology is discussed.","PeriodicalId":10739,"journal":{"name":"Current Directions in Biomedical Engineering","volume":"165 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135394998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multifrequency bioimpedance device based on the Analog Discovery 2: performance and characterization 基于模拟发现的多频生物阻抗器件2:性能与表征

Current Directions in Biomedical Engineering Pub Date : 2023-09-01 DOI: 10.1515/cdbme-2023-1134

Alberto Battistel, Hegoa Craamer Lizarraga, Maite Termenon, Knut Möller

{"title":"Multifrequency bioimpedance device based on the Analog Discovery 2: performance and characterization","authors":"Alberto Battistel, Hegoa Craamer Lizarraga, Maite Termenon, Knut Möller","doi":"10.1515/cdbme-2023-1134","DOIUrl":"https://doi.org/10.1515/cdbme-2023-1134","url":null,"abstract":"Abstract Bioimpedance spectroscopy can be used to investigate the composition and monitor the human body, organs, tissues, or cell cultures by measuring the voltage developed by the injection of small alternating currents at different frequencies. These currents are injected sequentially through a frequency sweep and a with a Howland current source or one of its modifications. However, the frequency sweep is not time efficient and introduces problems with data coherence in the case of bioinstability. On the other hand, the Howland current source requires high precision matching between its components. In this contribution we developed a custom-made device for bioimpedance measurements based on a multisine current waveform and on a negative-feedback topology for the current source. Measurements on passive elements showed that the device had less than 1Ω and 0.05∘ uncertainty in the frequency range between 500 Hz and 200 kHz for impedance between 1 kΩ and 10 kΩ. The measurements were affected by an inductive artifact connected with the limited common-mode rejection at high frequencies. Nevertheless, we could characterize the artifacts through a fitting procedure to recover the expected value of the targeted impedance.","PeriodicalId":10739,"journal":{"name":"Current Directions in Biomedical Engineering","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135393474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep Learning by Domain Transfer for Early Tumor Detection in the Urinary Bladder 基于领域转移的深度学习用于膀胱早期肿瘤检测

Current Directions in Biomedical Engineering Pub Date : 2023-09-01 DOI: 10.1515/cdbme-2023-1014

Thomas Wittenberg, Thomas Eixelberger, Stephan Kruck, Sebastian Belle, Maximilian Kriegmair, Christian Bolenz, Philip Maisch

{"title":"Deep Learning by Domain Transfer for Early Tumor Detection in the Urinary Bladder","authors":"Thomas Wittenberg, Thomas Eixelberger, Stephan Kruck, Sebastian Belle, Maximilian Kriegmair, Christian Bolenz, Philip Maisch","doi":"10.1515/cdbme-2023-1014","DOIUrl":"https://doi.org/10.1515/cdbme-2023-1014","url":null,"abstract":"Abstract Background: Bladder cancer (BCa) is the second most common genitourinary malignancy and has a mortality of 165,000 deaths p.a. The diagnosis of BCa is mostly carried out using cystoscopy - the visual examination of the urinary bladder with an endoscope. White light cystoscopy is currently considered as gold standard for the diagnosis. Nevertheless, especially flat, small or weakly textured lesions, are very difficult to detect and diagnose. Objective: With the advent of deep learning and already commercially available systems for the detection of adenomas in colonoscopy, it is investigated how such a system - for colonoscopy - performs if retrained and tested with cystoscopy images. Methods: A deep neural network with a YOLOv7-tiny architecture was pre-trained on 35,699 colonoscopy images (partially from Mannheim), yielding a precision = 0.92, sensitivity = 0.90, F1 = 0.91 on public colonoscopy data collections. Results: Testing this adenomadetection network with cystoscopy images from three sources (Ulm, Erlangen, Pforzheim), F1 scores in the range of 0.67 to 0.74 could be achieved. The network was then retrained with 12,066 cystoscopy images (from Mannheim), yielding improved F1 scores in the range of 0.78 to 0.85. Conclusion: It could be shown that a deep learning network for adenoma detection in colonoscopy is ad-hoc able to detect approximately 75% of the lesions in the urinary bladder in cystoscopy images, suggesting that these lesions have a similar appearance. After retraining the network with additional cystoscopy data, the performance for urinary lesion detection could be improved, indicating that a domain-shift with adequate additional data is feasible.","PeriodicalId":10739,"journal":{"name":"Current Directions in Biomedical Engineering","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135393935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PH-triggered drug release of ciprofloxacin from layer-by-layer coatings on titanium ph触发的环丙沙星从钛上逐层涂层中释放

Current Directions in Biomedical Engineering Pub Date : 2023-09-01 DOI: 10.1515/cdbme-2023-1009

Nina Ehlert, Desiree Rieks, Andreas Kampmann, Nils-Claudius Gellrich

引用次数: 0

Method for CAD/CAM-based production of patient-specific anatomical bone surrogates from polyurethane rigid foams of different densities for various clinical applications 基于CAD/ cam的基于不同密度聚氨酯硬泡沫的临床应用的患者特异性解剖骨替代物生产方法

Current Directions in Biomedical Engineering Pub Date : 2023-09-01 DOI: 10.1515/cdbme-2023-1020

Philipp Sembdner, Karl Blaurock, Kristin Paetzold-Byhain

{"title":"Method for CAD/CAM-based production of patient-specific anatomical bone surrogates from polyurethane rigid foams of different densities for various clinical applications","authors":"Philipp Sembdner, Karl Blaurock, Kristin Paetzold-Byhain","doi":"10.1515/cdbme-2023-1020","DOIUrl":"https://doi.org/10.1515/cdbme-2023-1020","url":null,"abstract":"Abstract Physical models of bony areas are used in the medical environment for training, patient information or for various examinations. These are idealized average models which, however, do not reflect the individuality of a respective patient. Furthermore, the mechanical properties of the bony structure with cortical bone and cancellous bone are not considered in most models. A few manufacturers, such as SawBone, offer models and material blocks that approximate the properties of the bone. However, these are not patientspecific either. This paper presents a proposal for a method to create patient-specific physical bone models with CAD/CAM technologies that approximate shape and mechanical properties. The models are made of two different rigid polyurethane foams for cortical bone and cancellous bone. The methodical development includes the elaboration of a framework starting from the patient's CT data, through design derivation, to fabrication. Furthermore, a possible process for fabrication in the form of a demonstrator and its application in sawing tests will be demonstrated.","PeriodicalId":10739,"journal":{"name":"Current Directions in Biomedical Engineering","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135393943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enabling Data-Driven Nursing Innovations: User-centered Development of a Nursing Data Module 实现数据驱动的护理创新:以用户为中心的护理数据模块开发

Current Directions in Biomedical Engineering Pub Date : 2023-09-01 DOI: 10.1515/cdbme-2023-1085

Maren Warnecke, Daniela Holle, Anja Burmann

引用次数: 0

Fabrication and characterization of CMOS-compatible perforated micromembranes for biomedical applications 生物医学用cmos兼容穿孔微膜的制备与表征

Current Directions in Biomedical Engineering Pub Date : 2023-09-01 DOI: 10.1515/cdbme-2023-1110

Noah Brechmann, Marvin Michel, Alina Bola, Franziska Renz, Andreas Pickhinke, Karsten Seidl

引用次数: 0

Temporal bone phantom for decoupled cochlear implant electrode insertion force measurement 解耦人工耳蜗电极插入力测量的颞骨模体

Current Directions in Biomedical Engineering Pub Date : 2023-09-01 DOI: 10.1515/cdbme-2023-1033

Jakob Cramer, Niklas Dassow, Georg Böttcher-Rebmann, Thomas Lenarz, Thomas S. Rau, Leon Budde

{"title":"Temporal bone phantom for decoupled cochlear implant electrode insertion force measurement","authors":"Jakob Cramer, Niklas Dassow, Georg Böttcher-Rebmann, Thomas Lenarz, Thomas S. Rau, Leon Budde","doi":"10.1515/cdbme-2023-1033","DOIUrl":"https://doi.org/10.1515/cdbme-2023-1033","url":null,"abstract":"Abstract In research on cochlear implants, preclinical testing of newly developed electrode arrays and surgical tools is an essential procedure, which requires the availability of a suitable testing environment. For this purpose, human temporal bone specimens are most realistic, but their availability is limited and additional parameters such as insertion forces are hardly measurable. Therefore, the aim of this study was to develop a temporal bone phantom with realistic anatomical structures for intracochlear force measurement. The temporal bone was segmented from CBCT data of a human cadaver head. The segmented model was 3D printed with an additional artificial skin layer to enable the simulated use of surgical instruments such as a self-retaining retractor. A mechanically decoupled artificial cochlear model was realistically positioned within the temporal bone and was furthermore attached to a force sensor. The usability of the phantom was evaluated by performing automated EA insertions using an automated hydraulic insertion device. The experiments showed that the insertion forces within the cochlea could be measured without interferences from surrounding structures. Moreover, the artificial skin provided a rigid interface for the insertion tool. The new phantom is a realistic testing and training platform for cochlear implant electrode insertions with the advantage of measureable insertion forces.","PeriodicalId":10739,"journal":{"name":"Current Directions in Biomedical Engineering","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135394993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0