Clinical radiology最新文献

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Cardiac magnetic resonance imaging to predict left ventricular reverse remodelling in non-ischaemic dilated cardiomyopathy: a systematic review and meta-analysis 心脏磁共振成像预测非缺血性扩张型心肌病左心室反向重构:系统回顾和荟萃分析
IF 2.1 3区 医学
Clinical radiology Pub Date : 2025-05-09 DOI: 10.1016/j.crad.2025.106950
B.S. Berdibekov, S.A. Alexandrova, N.I. Bulaeva, E.Z. Golukhova
{"title":"Cardiac magnetic resonance imaging to predict left ventricular reverse remodelling in non-ischaemic dilated cardiomyopathy: a systematic review and meta-analysis","authors":"B.S. Berdibekov,&nbsp;S.A. Alexandrova,&nbsp;N.I. Bulaeva,&nbsp;E.Z. Golukhova","doi":"10.1016/j.crad.2025.106950","DOIUrl":"10.1016/j.crad.2025.106950","url":null,"abstract":"<div><h3>AIM</h3><div>This systematic review and meta-analysis aimed to evaluate the predictive value of cardiac magnetic resonance (CMR) imaging parameters for left ventricular reverse remodelling (LVRR) in patients with nonischaemic dilated cardiomyopathy (DCM).</div></div><div><h3>MATERIALS AND METHODS</h3><div>Electronic databases were searched for studies examining late gadolinium enhancement (LGE), native T1, and extracellular volume (ECV). A random-effect meta-analysis was conducted, with heterogeneity assessed using the I<sup>2</sup> statistic.</div></div><div><h3>RESULTS</h3><div>Seventeen studies involving 1,465 participants (mean age: 54.3 years; LGE prevalence: 31%-69%) were included, with an average follow-up of 18.6 months. LGE was a strong univariate predictor of LVRR (pooled odds ratio [OR]: 3.65; 95% confidence interval [CI]: 2.45 to 5.45). A meta-analysis of three studies showed that LGE remained predictive after adjustment for baseline characteristics (pooled adjusted OR: 2.84; 95% CI: 1.50-5.37). Patients without LVRR had a greater LGE extent (weighted mean difference [MD]: 4.19%; 95% CI: 2.40%-5.97%), longer native T1 times (weighted MD: 44.84 ms; 95% CI: 25.92-63.76 ms), and higher ECV (weighted MD: 4.33%; 95% CI: 2.40%-6.26%).</div></div><div><h3>CONCLUSION</h3><div>The absence of LGE is a robust predictor of LVRR, even after adjustment for baseline characteristics. Patients with LVRR demonstrated lower LGE extent, shorter T1 times, and lower ECV, underscoring the utility of these CMR markers as indicators of myocardial recovery. Future research should focus on incorporating CMR parameters into clinical decision-making algorithms to enhance the management and outcomes of patients with DCM.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106950"},"PeriodicalIF":2.1,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intra-Sylvian versus intracerebral haematoma associated with ruptured middle cerebral artery aneurysm: initial and follow-up imaging features 脑中动脉瘤破裂伴脑内血肿与脑内血肿:初始和随访影像特征
IF 2.1 3区 医学
Clinical radiology Pub Date : 2025-05-09 DOI: 10.1016/j.crad.2025.106951
J.I. Hwang , D.Y. Yoon , E.S. Kim , H.J. Jeon , J.Y. Lee , Y.L. Seo , E.J. Yun
{"title":"Intra-Sylvian versus intracerebral haematoma associated with ruptured middle cerebral artery aneurysm: initial and follow-up imaging features","authors":"J.I. Hwang ,&nbsp;D.Y. Yoon ,&nbsp;E.S. Kim ,&nbsp;H.J. Jeon ,&nbsp;J.Y. Lee ,&nbsp;Y.L. Seo ,&nbsp;E.J. Yun","doi":"10.1016/j.crad.2025.106951","DOIUrl":"10.1016/j.crad.2025.106951","url":null,"abstract":"<div><h3>AIM</h3><div>The aim of this study was to evaluate and compare the initial and follow-up imaging features of intra-Sylvian haematoma (ISH) and intracerebral haematoma (ICH) from a ruptured middle cerebral artery (MCA) aneurysm.</div></div><div><h3>MATERIALS AND METHODS</h3><div>We retrospectively evaluated and compared the imaging features of 24 patients with ISH and 46 with ICH from ruptured MCA aneurysms. The following features in initial computed tomography, computed tomography angiography, and magnetic resonance (MR) imaging were investigated: density (Hounsfield unit) and margin of the haematoma, low density surrounding the haematoma, morphological parameters of the aneurysm, early severe vasospasm of M1 and M2 segments, active rebleeding, and high b1000 signal intensity and low apparent diffusion coefficient (ADC) surrounding the haematoma on MR diffusion-weighted imaging (DWI). Additionally, we assessed delayed severe vasospasm and the distribution of cerebromalacia on follow-up imaging examinations.</div></div><div><h3>RESULTS</h3><div>Compared to the ICH group, the ISH group showed a more frequent haematoma with serrated margins (100% vs 21.7%, <em>P</em>=0.000), absent or uniform thickness low density surrounding the haematoma (75.0% vs 15.2%, <em>P</em>=0.000), early severe vasospasm of M1 and M2 segments (83.3% vs 41.3%, <em>P</em>=0.001), thick (&gt;5 mm) high b1000 signal intensity and low ADC surrounding the haematoma on MR DWI (100% vs 27.8%, <em>P</em>=0.001), delayed severe vasospasm at days 7 (±1) (100% vs 61.5%, <em>P</em>&lt;0.05), and cerebromalacia involving brain surrounding the Sylvian fissure at 3 to 12 months (71.4% vs 0%, <em>P</em>=0.000).</div></div><div><h3>CONCLUSION</h3><div>Initial and follow-up imaging features can help differentiate between ISH and ICH associated with ruptured MCA aneurysm, facilitating appropriate treatment in the course of the disease.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106951"},"PeriodicalIF":2.1,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of thyroid-associated ophthalmopathy activity using corrected standardised uptake value maximum (SUVmax) and uptake ratios from 99Tcm-diethylene triamine pentaacetic acid single photon emission computed tomography/computed tomography (99Tcm-DTPA SPECT/CT) imaging 使用99tcm -二乙烯三胺五乙酸单光子发射计算机断层扫描/计算机断层扫描(99Tcm-DTPA SPECT/CT)成像的校正标准最大摄取值(SUVmax)和摄取比率评估甲状腺相关眼病活动性
IF 2.1 3区 医学
Clinical radiology Pub Date : 2025-05-06 DOI: 10.1016/j.crad.2025.106946
J. Sun , L. Ma , M. Wang , X. Yuan
{"title":"Assessment of thyroid-associated ophthalmopathy activity using corrected standardised uptake value maximum (SUVmax) and uptake ratios from 99Tcm-diethylene triamine pentaacetic acid single photon emission computed tomography/computed tomography (99Tcm-DTPA SPECT/CT) imaging","authors":"J. Sun ,&nbsp;L. Ma ,&nbsp;M. Wang ,&nbsp;X. Yuan","doi":"10.1016/j.crad.2025.106946","DOIUrl":"10.1016/j.crad.2025.106946","url":null,"abstract":"<div><h3>Aim</h3><div>This study evaluated the utility of corrected maximum standardized uptake value (SUVmax) in assessing thyroid-associated ophthalmopathy (TAO) activity through 99Tcm-diethylene triamine pentaacetic acid (99Tcm-DTPA) SPECT/CT imaging.</div></div><div><h3>Materials and Methods</h3><div>A total of 166 orbits from 83 TAO patients were analyzed, alongside 22 orbits from 11 healthy controls. Participants were cate gorized into active (CAS ≥ 3), inactive (CAS &lt;3), and control groups based on the clinical activity score (CAS). Corrected SUVmax and uptake ratios (UR) were quantitatively measured using Q.Metrix software. Statistical analyses, including Kruskale-Wallis tests, Spearman correlations, and ROC curve evaluations, were employed to examine group differences and diagnostic performance.</div></div><div><h3>Results</h3><div>The corrected SUVmax and UR values were significantly higher in the active group compared to inactive and control groups (P&lt;0.001). Corrected SUVmax demonstrated strong reproducibility (ICC = 0.958) and a positive correlation with CAS (rs = 0.537, P&lt;0.001), outperforming UR in consistency (ICC = 0.632). ROC analysis revealed that the corrected SUVmax threshold of 10.440 offered 70.7% sensitivity and 82.1% specificity for predicting TAO activity. UR exhibited comparable diagnostic performance but with reduced reproducibility.</div></div><div><h3>Conclusion</h3><div>These findings highlight corrected SUVmax as a robust and reliable parameter for quantifying TAO inflammatoryactivity. Its strong correlation with CAS and high interobserver agreement establish its potential for clinical use in guiding TAO treatment and monitoring disease progression. Further multicenter studies are warranted to validate these findings and expand clinical applications.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106946"},"PeriodicalIF":2.1,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reduction of radiation dose and contrast medium volume in computed tomography pulmonary angiography: adaptation of dual-energy computed tomography (CT) protocols to the body mass index 计算机断层肺血管造影中降低辐射剂量和造影剂体积:双能计算机断层扫描(CT)方案对身体质量指数的适应
IF 2.1 3区 医学
Clinical radiology Pub Date : 2025-04-30 DOI: 10.1016/j.crad.2025.106944
X. Zhang , H. Huang , Y. Huang , Y. Sun , Z. Chen , M. Chen , J. Xu
{"title":"Reduction of radiation dose and contrast medium volume in computed tomography pulmonary angiography: adaptation of dual-energy computed tomography (CT) protocols to the body mass index","authors":"X. Zhang ,&nbsp;H. Huang ,&nbsp;Y. Huang ,&nbsp;Y. Sun ,&nbsp;Z. Chen ,&nbsp;M. Chen ,&nbsp;J. Xu","doi":"10.1016/j.crad.2025.106944","DOIUrl":"10.1016/j.crad.2025.106944","url":null,"abstract":"<div><h3>Aim</h3><div>To evaluate the image quality and diagnostic value of a body mass index (BMI)-based dual-energy computed tomography (CT) protocol in computed tomography pulmonary angiography (CTPA) for reduction of radiation dose and contrast medium (CM) volume.</div></div><div><h3>Materials and Methods</h3><div>Patients suspected of having pulmonary embolism were prospectively included and randomly assigned to one of three protocols: Protocol A (a standard protocol, 100 kV/140 mAs/50 mL iodinated CM), B (a conventional dual-energy protocol, 80–140 kV switching/automatic tube current/weight-dependent CM volume) and C (a BMI-based dual-energy protocol, 80–140 kV switching/BMI-based tube current/weight-dependent CM volume, BMI-based CM injection rate). Subjective and objective image analysis were performed by two radiologists independently. Diagnostic accuracy of pulmonary embolism were evaluated. Inter-group comparison was performed.</div></div><div><h3>Results</h3><div>Ninety patients (mean age 54.1 ± 13.3 years, 57 men) were included, with 30 patients in each group. The CT values, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) of the pulmonary arteries in group C were significantly higher than those in group B (358.2 ± 50.5 vs 324.9 ± 57.2, <em>p</em>=0.047, 17.8 ± 3.2 vs 15.3 ± 2.9, <em>p</em>=0.010, 19.2 ± 4.1 vs 15.7 ± 3.8, <em>p</em>=0.014). The dose length product (DLP) and CM volume were significantly reduced in groups B and C (A vs B vs C, DLP, 287.9 ± 34.0 vs 177.2 ± 39.2 vs 183.8 ± 23.1 mGy·cm), <em>p</em>&lt;0.001, CM, 50.0 ± 0.0 vs 22.1 ± 3.0 vs 23.2 ± 4.0 ml, <em>p</em>&lt;0.001). There were no significant differences in diagnostic accuracy or subjective image quality among the three groups.</div></div><div><h3>Conclusion</h3><div>The BMI-based dual-energy CT protocol can reduce radiation exposure and iodine burden compared to routine CTPA without affecting the image quality and diagnostic accuracy in patients with a BMI under 30 kg/m<sup>2</sup>.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106944"},"PeriodicalIF":2.1,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144105895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal function and iodinated contrast media: a National Institute for Health and Care Excellence update 肾功能和碘造影剂:国家健康和护理卓越研究所更新
IF 2.1 3区 医学
Clinical radiology Pub Date : 2025-04-30 DOI: 10.1016/j.crad.2025.106940
R.D. Proctor , W.S. McKane , F. Awan , T. Oates , J.A. Stephenson , T. Sands , A. Morris , M. Brady , A.J.P. Lewington , J.S. Murray
{"title":"Renal function and iodinated contrast media: a National Institute for Health and Care Excellence update","authors":"R.D. Proctor ,&nbsp;W.S. McKane ,&nbsp;F. Awan ,&nbsp;T. Oates ,&nbsp;J.A. Stephenson ,&nbsp;T. Sands ,&nbsp;A. Morris ,&nbsp;M. Brady ,&nbsp;A.J.P. Lewington ,&nbsp;J.S. Murray","doi":"10.1016/j.crad.2025.106940","DOIUrl":"10.1016/j.crad.2025.106940","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106940"},"PeriodicalIF":2.1,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differentiation of benign, intermediate, and malignant soft-tissue tumours by using multiple diffusion-weighted imaging models 利用多重弥散加权成像模型鉴别软组织良性、中度和恶性肿瘤
IF 2.1 3区 医学
Clinical radiology Pub Date : 2025-04-26 DOI: 10.1016/j.crad.2025.106942
K. Zhang , Y. Dai , C. Yu , J. Liu , Y. Cheng , Y. Zhou , Y. Liu , J. Tao , L. Zhang , S. Wang
{"title":"Differentiation of benign, intermediate, and malignant soft-tissue tumours by using multiple diffusion-weighted imaging models","authors":"K. Zhang ,&nbsp;Y. Dai ,&nbsp;C. Yu ,&nbsp;J. Liu ,&nbsp;Y. Cheng ,&nbsp;Y. Zhou ,&nbsp;Y. Liu ,&nbsp;J. Tao ,&nbsp;L. Zhang ,&nbsp;S. Wang","doi":"10.1016/j.crad.2025.106942","DOIUrl":"10.1016/j.crad.2025.106942","url":null,"abstract":"<div><h3>AIM</h3><div>The aim of this study was to determine whether intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) can differentiate benign, intermediate, and malignant soft-tissue tumours (STTs) of the extremities and trunk.</div></div><div><h3>MATERIALS AND METHODS</h3><div>We prospectively recruited 100 STT patients (32, 15, and 53 patients with benign, intermediate, and malignant tumours, respectively). The patients underwent IVIM and DKI, and the following parameters were measured: standard apparent diffusion coefficient (ADC), perfusion fraction (<em>f</em>), true diffusion coefficient (D<sub>slow</sub>), pseudo-diffusion coefficient (D<sub>fast</sub>), water diffusion heterogeneity index (α), distributed diffusion coefficient (DDC), mean diffusivity (MD), and mean kurtosis (MK). Statistical analyses were performed using receiver operating characteristic curves, the Kruskal-Wallis H test, and post hoc test with Bonferroni correction.</div></div><div><h3>RESULTS</h3><div>Standard ADC, D<sub>slow</sub>, DDC, and MD values gradually decreased from benign to intermediate and malignant STTs. Intermediate STTs displayed a lower <em>f</em> value than benign tumours (<em>P</em>=0.029). The MK value was higher in malignant tumours than in intermediate and benign tumours (<em>P</em>=0.021 and &lt;0.001, respectively). The DDC value best differentiated benign tumours from nonbenign (intermediate and malignant) tumours (area under the curve [AUC] = 0.884, 0853, and 0.892, respectively). The optimal MK cut-off value for differentiating intermediate and malignant tumours was 0.65 (sensitivity: 73.33%, specificity: 81.13%, accuracy: 79.41%).</div></div><div><h3>CONCLUSION</h3><div>IVIM and DKI parameters were helpful for differentiating benign, intermediate, and malignant STTs and can complement conventional MRI, with DDC and MK values showing high diagnostic efficacy.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106942"},"PeriodicalIF":2.1,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144105847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the correlation between high-risk coronary plaque and hepatic fat fraction in non-alcoholic fatty liver disease using spectral computed tomography (CT) 非酒精性脂肪性肝病高危冠状动脉斑块与肝脏脂肪分数的相关性研究
IF 2.1 3区 医学
Clinical radiology Pub Date : 2025-04-26 DOI: 10.1016/j.crad.2025.106943
Q. Li , T. Cui , H. Ding , X. Shi , Y. Zhang , P. Jiang , J. Han , J. Li , J. Liu
{"title":"Exploring the correlation between high-risk coronary plaque and hepatic fat fraction in non-alcoholic fatty liver disease using spectral computed tomography (CT)","authors":"Q. Li ,&nbsp;T. Cui ,&nbsp;H. Ding ,&nbsp;X. Shi ,&nbsp;Y. Zhang ,&nbsp;P. Jiang ,&nbsp;J. Han ,&nbsp;J. Li ,&nbsp;J. Liu","doi":"10.1016/j.crad.2025.106943","DOIUrl":"10.1016/j.crad.2025.106943","url":null,"abstract":"<div><h3>Aim</h3><div>To quantitatively assess the fat volume fraction (FVF) in nonalcoholic fatty liver disease (NAFLD) using the spectral computed tomography (CT) multimaterial decomposition (MMD) algorithm and to investigate its association with high-risk coronary plaques (HRP).</div></div><div><h3>Materials and Methods</h3><div>This retrospective study included patients diagnosed with coronary artery disease (CAD) from August 2023 to August 2024 who underwent coronary CT angiography and abdominal enhanced spectral CT imaging. Patients were categorised into three groups based on HRP imaging features (positive remodelling, low-density plaques, spotty calcification, and napkin ring sign): no plaque (n = 57), non-HRP (n = 54), and HRP (n = 48) groups. FVF was measured using the spectral CT MMD algorithm to quantify liver fat content. Clinical characteristics, biochemical markers, and imaging differences among the groups were analysed. Univariate and multivariate logistic regression analyses were performed to determine the association between FVF and HRP.</div></div><div><h3>Results</h3><div>FVF values were significantly higher in the HRP group (13.2%) compared to the non-HRP group (9.2%) and the no plaque group (6.5%) (P&lt;0.001). Multivariate binary logistic regression analysis identified FVF as an independent risk factor for HRP (odds ratio [OR]: 2.55, P&lt;0.001), along with high-sensitivity C-reactive protein (hs-CRP) (OR: 1.94, P=0.025) and diabetes mellitus (OR: 9.83, P=0.002). Additionally, FVF correlated epicardial and pericoronary adipose tissue (PCAT) volume and CT attenuation (P&lt;0.001).</div></div><div><h3>Conclusion</h3><div>The spectral CT MMD algorithm enables quantitative assessment of FVF, which is independently associated with coronary HRP formation in NAFLD patients. Elevated FVF serves as a risk factor for CAD in patients with NAFLD.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106943"},"PeriodicalIF":2.1,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144105850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breast tumour classification in DCE-MRI via cross-attention and discriminant correlation analysis enhanced feature fusion 基于交叉注意和判别相关分析的DCE-MRI乳腺肿瘤分类增强了特征融合
IF 2.1 3区 医学
Clinical radiology Pub Date : 2025-04-24 DOI: 10.1016/j.crad.2025.106941
F. Pan , B. Wu , X. Jian , C. Li , D. Liu , N. Zhang
{"title":"Breast tumour classification in DCE-MRI via cross-attention and discriminant correlation analysis enhanced feature fusion","authors":"F. Pan ,&nbsp;B. Wu ,&nbsp;X. Jian ,&nbsp;C. Li ,&nbsp;D. Liu ,&nbsp;N. Zhang","doi":"10.1016/j.crad.2025.106941","DOIUrl":"10.1016/j.crad.2025.106941","url":null,"abstract":"<div><h3>Aim</h3><div>Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has proven to be highly sensitive in diagnosing breast tumours, due to the kinetic and volumetric features inherent in it. To utilise the kinetics-related and volume-related information, this paper aims to develop and validate a classification for differentiating benign and malignant breast tumours based on DCE-MRI, though fusing deep features and cross-attention-encoded radiomics features using discriminant correlation analysis (DCA).</div></div><div><h3>Materials and methods</h3><div>Classification experiments were conducted on a dataset comprising 261 individuals who underwent DCE-MRI including those with multiple tumours, resulting in 137 benign and 163 malignant tumours. To improve the strength of correlation between features and reduce features’ redundancy, a novel fusion method that fuses deep features and encoded radiomics features based on DCA (eFF-DCA) is proposed. The eFF-DCA includes three components: (1) a feature extraction module to capture kinetic information across phases, (2) a radiomics feature encoding module employing a cross-attention mechanism to enhance inter-phase feature correlation, and (3) a DCA-based fusion module that transforms features to maximise intra-class correlation while minimising inter-class redundancy, facilitating effective classification.</div></div><div><h3>Results</h3><div>The proposed eFF-DCA method achieved an accuracy of 90.9% and an area under the receiver operating characteristic curve of 0.942, outperforming methods using single-modal features.</div></div><div><h3>Conclusion</h3><div>The proposed eFF-DCA utilises DCE-MRI kinetic-related and volume-related features to improve breast tumour diagnosis accuracy, but non–end-to-end design limits multimodal fusion. Future research should explore unified end-to-end deep learning architectures that enable seamless multimodal feature fusion and joint optimisation of feature extraction and classification.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106941"},"PeriodicalIF":2.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144105849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic value of quantitative brain synthetic magnetic resonance imaging in patients with obstructive sleep apnoea 定量脑合成磁共振成像对阻塞性睡眠呼吸暂停的诊断价值
IF 2.1 3区 医学
Clinical radiology Pub Date : 2025-04-24 DOI: 10.1016/j.crad.2025.106939
Y. Li , X. Du , Z. Geng
{"title":"Diagnostic value of quantitative brain synthetic magnetic resonance imaging in patients with obstructive sleep apnoea","authors":"Y. Li ,&nbsp;X. Du ,&nbsp;Z. Geng","doi":"10.1016/j.crad.2025.106939","DOIUrl":"10.1016/j.crad.2025.106939","url":null,"abstract":"<div><h3>Aim</h3><div>Investigating the diagnostic value of quantitative brain synthetic magnetic resonance imaging (SyMRI) in adult patients with obstructive sleep apnoea (OSA) and brain microstructural injury.</div></div><div><h3>Materials and Methods</h3><div>Fifty untreated OSA patients at initial diagnosis who were diagnosed were collected as the OSA group, with 36 non-OSA patients as the normal group. Afterwards, all subjects underwent cranial scans using GE SIGNA Architect 3.0T magnetic resonance imaging. Meanwhile, the differences in grey matter relaxation values, white matter relaxation values, and proton density (PD) values between the 2 groups were compared, followed by an analysis of the correlation between the above parameters and apnoea–hypopnoea index (AHI).</div></div><div><h3>Results</h3><div>Compared with the normal group, T2 values of grey and white matter were significantly decreased, and T1 and PD values of grey matter were slightly decreased in the OSA group, with significant differences (<em>P</em>&lt;005). In the meantime, receiver operating characteristic curves suggested the highest area under the curve (AUC) (0.74) and a high sensitivity (92.0%) of T2 values of white matter, along with a low specificity (52.0%). Additionally, the T1 and T2 values of grey matter shared the same AUC (0.69), which exhibited high specificity (75.0%) and high sensitivity (92.0%), respectively. Furthermore, Spearman correlation analysis indicated that T1 values of grey matter were positively correlated with AHI, while T2 values of grey and white matter were negatively correlated with AHI (<em>P</em>&lt;0.05).</div></div><div><h3>Conclusion</h3><div>SyMRI quantitative imaging parameters are of significant clinical value for adult OSA patients, especially T2 relaxation values, which are beneficial for the early diagnosis of brain microstructural injury.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106939"},"PeriodicalIF":2.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144178327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Initial experience with adrenal vein sampling using 3D cursor and preprocedural computed tomography (CT) scout image 使用3D光标和术前计算机断层扫描(CT)侦察图像进行肾上腺静脉采样的初步经验
IF 2.1 3区 医学
Clinical radiology Pub Date : 2025-04-22 DOI: 10.1016/j.crad.2025.106928
M.S. Kim , H.P. Hong , C.-Y. Park , J.-S. Yun , H. Kwon , J.N. Kim , M. Kim , K.H. Lee
{"title":"Initial experience with adrenal vein sampling using 3D cursor and preprocedural computed tomography (CT) scout image","authors":"M.S. Kim ,&nbsp;H.P. Hong ,&nbsp;C.-Y. Park ,&nbsp;J.-S. Yun ,&nbsp;H. Kwon ,&nbsp;J.N. Kim ,&nbsp;M. Kim ,&nbsp;K.H. Lee","doi":"10.1016/j.crad.2025.106928","DOIUrl":"10.1016/j.crad.2025.106928","url":null,"abstract":"<div><h3>AIM</h3><div>To evaluate the success rate and learning curve of adrenal vein sampling (AVS) performed by a single interventional radiologist, using CT scout image marked with a 3D cursor.</div></div><div><h3>MATERIALS AND METHODS</h3><div>The AVS procedure was conducted on 135 consecutive patients between January 2020 and December 2022 by a single interventional radiologist with no prior experience with AVS. Using a 3D cursor, the positions of the right adrenal vein (RAV), left adrenal vein (LAV), and left renal vein were marked on the CT scout image. AVS procedures were performed based on the marked scout image.</div></div><div><h3>RESULTS</h3><div>Of 135 AVS procedures, 123 (91.1%) were successful with success rates of 82.1% (23/28), 90.4% (47/52), and 96.4% (53/55) in the first, second, and third years, respectively. Among the 12 failures, 10 occurred on the right side and 2 on the left side. The reasons for failure were failure to locate the RAV (n=5), misidentification of a vessel as the adrenal vein (right, n=4; left, n=1), RAV sample haemolysis (n=1), and the absence of adrenocorticotrophic hormone (ACTH) stimulation (LAV, n=1). Three of the failed cases (misidentified RAV, n=1; sample haemolysis, n=1; and no ACTH stimulation, n=1) underwent repeat AVS, and all were successful.</div></div><div><h3>CONCLUSION</h3><div>AVS can be successfully performed by an operator without prior AVS experience using a 3D cursor and CT scout imaging. The success rate of AVS increases with the operator experience.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106928"},"PeriodicalIF":2.1,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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