Clinical radiology最新文献_第3页

T1 mapping of the sagittal images of the cervical cord: a potential biomarker to predict the severity of cervical spondylotic myelopathy 颈髓矢状图像的T1映射：预测脊髓型颈椎病严重程度的潜在生物标志物

IF 2.1 3区医学

Clinical radiology Pub Date : 2025-05-27 DOI: 10.1016/j.crad.2025.106974

X. Wang , X. Tian , Y. Peng , D. Zhang , Y. Wang , L. Zhang

{"title":"T1 mapping of the sagittal images of the cervical cord: a potential biomarker to predict the severity of cervical spondylotic myelopathy","authors":"X. Wang , X. Tian , Y. Peng , D. Zhang , Y. Wang , L. Zhang","doi":"10.1016/j.crad.2025.106974","DOIUrl":"10.1016/j.crad.2025.106974","url":null,"abstract":"<div><h3>Aims</h3><div>To investigate the applied value of quantitative assessment of the cervical spondylotic myelopathy (CSM) severity using T1 mapping of cervical spinal cord.</div></div><div><h3>Materials and Methods</h3><div>A total of 133 patients with CSM (CSM group) and 30 healthy volunteers (control group) were prospectively recruited between September 2023 and March 2024. Patients with CSM were categorized into a mild group (mJOA ≥12) and a severe group (mJOA <12) according to the modified Japanese Orthopedic Association scores (mJOA). Cervical axial and sagittal T2WI, as well as sagittal T1 mapping were performed on all subjects. In the control group, native T1 was measured at each disc level (C2–C7); in the CSM group, native T1 was measured at the stenotic location, the disc level above and below the stenotic location (T1<sub>stenosis</sub>,T1<sub>above</sub> and T1<sub>below</sub>). Interobserver agreement, univariate analyses, pearson's correlations, and ROC curves were performed.</div></div><div><h3>Results</h3><div>Native T1 showed excellent interobserver agreement in the control group. The mean T1 value of the control group (772.94 ± 57.87 ms) was significantly lower than the T1<sub>stenosis</sub>(908.89 ± 135.61ms),T1<sub>above</sub> (844.66 ± 126.97ms) and T1 <sub>below</sub> (855.99 ± 125.52ms).The distribution of mJOA, T2(+), T1 <sub>stenosis</sub>, T1<sub>above</sub> and T1<sub>below</sub> between the mild and severe groups differed (P<0.05). All native T1 of CSM group showed negative correlations with mJOA. AUCs of T1 <sub>stenosis</sub>,T1<sub>above</sub> and T1<sub>below</sub> identified the severity of CSM patients as 0.857, 0.711, and 0.733, respectively.</div></div><div><h3>Conclusions</h3><div>T1 mapping can quantitatively assess the severity of CSM patients, and native T1 of spinal cord at the stenosis level is a valuable parameter to differentiate between patients with mild and severe CSM.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106974"},"PeriodicalIF":2.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A novel cervical MRI-vertebral bone quality score system for assessment of bone density in LenKe 5/6 type adolescent idiopathic scoliosis 一种评估LenKe 5/6型青少年特发性脊柱侧凸骨密度的新型颈椎mri椎体骨质量评分系统

IF 2.1 3区医学

Clinical radiology Pub Date : 2025-05-27 DOI: 10.1016/j.crad.2025.106975

D. Yang , Y. Chen , J. Gao , Y. Zhu , C. Liu

{"title":"A novel cervical MRI-vertebral bone quality score system for assessment of bone density in LenKe 5/6 type adolescent idiopathic scoliosis","authors":"D. Yang , Y. Chen , J. Gao , Y. Zhu , C. Liu","doi":"10.1016/j.crad.2025.106975","DOIUrl":"10.1016/j.crad.2025.106975","url":null,"abstract":"<div><h3>Aim</h3><div>To explore the application of the cervical vertebral bone quality (C-VBQ) score based on MRI in assessing bone mineral density (BMD) in LenKe 5/6 type adolescent idiopathic scoliosis (AIS) patients.</div></div><div><h3>Materials and Methods</h3><div>Lenke 5/6 AIS patients were retrospectively included between January 2016 and January 2024 and then were divided into normal and low BMD groups according to quantitative computed tomography (QCT). The VBQ scores and HU values were measured from MRI and CT. Three types of C-VBQs were obtained through different calculation methods, namely C-VBQ1/2/3. The correlations between QCT Z-score and C-VBQ scores/HU value were analyzed with Pearson correlation and linear regression. Receiver operating characteristic (ROC) analysis was performed to evaluate the diagnostic accuracy of C-VBQs and HU.</div></div><div><h3>Results</h3><div>One hundred and forty patients (52 in the normal group, 88 in the low BMD group) were included. Significant differences in HU value, C-VBQ1 and C-VBQ3 were found between groups. HU value, C-VBQ1 and C-VBQ3 were all significantly correlated to QCT Z-score (correlation coefficient (r): HU: 0.704, C-VBQ1: -0.493, C-VBQ3: -0.391, <em>P</em><0.001). The area-under-curve (AUC) of the ROC curve was calculated (HU: 0.816, C-VBQ1: 0.79, C-VBQ3: 0.701). The AUC of the combination of C-VBQ1 and HU value was 0.851. According to the Youden index, when a cutoff value was set at 326.37, 3.325 and 3.16 respectively, HU value, C-VBQ1 and C-VBQ3 had the best diagnosis performance in distinguishing low BMD.</div></div><div><h3>Conclusion</h3><div>The cervical-VBQ score was a promising tool in distinguishing low BMD in Lenke 5/6 type AIS patients and could be useful as opportunistic assessment for screening and complementary evaluation before surgery.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106975"},"PeriodicalIF":2.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144470981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on “Exploring the correlation between high-risk coronary plaque and hepatic fat fraction in non-alcoholic fatty liver disease using spectral CT” 《利用频谱CT探讨非酒精性脂肪肝患者高危冠状动脉斑块与肝脏脂肪分数的相关性》一文点评

IF 2.1 3区医学

Clinical radiology Pub Date : 2025-05-26 DOI: 10.1016/j.crad.2025.106970

R. Sah MD , A. Mathur MDS

引用次数: 0

Comment on “combining conventional MRI parameters with clinicopathologic data for differentiation of the three-tiered HER2 status in breast cancer” 对“结合常规MRI参数与临床病理资料鉴别乳腺癌HER2三级状态”的评析

IF 2.1 3区医学

Clinical radiology Pub Date : 2025-05-26 DOI: 10.1016/j.crad.2025.106971

R. Mehta, R. Sah

引用次数: 0

Morphological changes in the muscle layer associated with invasion of bladder cancer 膀胱癌侵袭后肌肉层形态学改变

IF 2.1 3区医学

Clinical radiology Pub Date : 2025-05-24 DOI: 10.1016/j.crad.2025.106973

T. Ohta , K. Okamoto , H. Inai , T. Takayama , K. Uchida

{"title":"Morphological changes in the muscle layer associated with invasion of bladder cancer","authors":"T. Ohta , K. Okamoto , H. Inai , T. Takayama , K. Uchida","doi":"10.1016/j.crad.2025.106973","DOIUrl":"10.1016/j.crad.2025.106973","url":null,"abstract":"<div><h3>AIM</h3><div>Although multiparametric magnetic resonance imaging (mpMRI) has been validated for depth diagnosis of bladder cancer (BC), this study was performed to examine the morphological changes in the muscle layer in cases with BC and to re-evaluate the diagnostic capability of T2-weighted imaging (T2WI).</div></div><div><h3>MATERIAL AND METHODS</h3><div>The study population consisted of 89 patients with BC examined by preoperative MRI. Morphological findings in the muscle layer were compared between cases of muscle-invasive bladder cancer (MIBC) and non–muscle-invasive bladder cancer (NMIBC), and the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of these findings were calculated.</div></div><div><h3>RESULTS</h3><div>Localised wall thickening, spinate elevation, and disruption or interruption were more common in MIBC, while NMIBC more commonly showed no such abnormal findings. In addition, the sensitivity, specificity, PPV, NPV, and diagnostic accuracy were 88.9%, 75.0%, 62.1%, 93.6%, and 79.4% for localised wall thickening; 96.0%, 93.8%, 87.6%, 98.1%, and 94.5% for spinate elevation; 100.0%, 83.6%, 73.7%, 100.0%, and 88.7% for disruption or interruption; and 72.9%, 98.1%, 94.6%, 88.8%, and 90.2% for any morphological changes.</div></div><div><h3>CONCLUSION</h3><div>Focussing on morphological changes in the bladder wall, T2WI may be useful for depth diagnosis of BC, as well as functional assessments such as diffusion-weighted imaging (DWI), dynamic contrast enhancement (DCE) imaging, and/or mpMRI such as VI-RADS.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106973"},"PeriodicalIF":2.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imaging and intervention for soft tissue tumours in the era of locoregional therapies and immunotherapy 局部治疗和免疫治疗时代软组织肿瘤的成像与干预。

IF 2.1 3区医学

Clinical radiology Pub Date : 2025-05-24 DOI: 10.1016/j.crad.2025.106969

S. Rehman , C. McCarthy , M. Chetan , Y.-L. Li , M. Gillies , T. Cosker , F. Wu , P.C. Lyon

{"title":"Imaging and intervention for soft tissue tumours in the era of locoregional therapies and immunotherapy","authors":"S. Rehman , C. McCarthy , M. Chetan , Y.-L. Li , M. Gillies , T. Cosker , F. Wu , P.C. Lyon","doi":"10.1016/j.crad.2025.106969","DOIUrl":"10.1016/j.crad.2025.106969","url":null,"abstract":"<div><div>As part of a multidisciplinary team, clinical radiology plays key roles in the diagnosis, staging and treatment response assessment for soft tissue sarcoma (STS) and desmoid tumours (DTs), typically using a combination of ultrasound and magnetic resonance imaging (MRI) modalities. There is an increasing role for interventional radiology in the treatment of recurrent and oligometastatic disease in these tumour types. This clinical radiology review is aimed primarily at non-specialist cross-sectional consultant radiologists and more junior radiology consultants/specialist trainees with a special interest in musculoskeletal oncology.</div><div>The existing role of F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and MRI for assessment of treatment response in STS and DT, including the emerging role of whole-body MRI is outlined. Response metrics including Response Evaluation Criteria in Solid Tumors 1.1 (RECIST 1.1), modified RECIST, Positron Emission Tomography Response Criteria in Solid Tumours (PERCIST), immune Response Evaluation Criteria in Solid Tumors, iPERCIST and non-perfused volume ratio are also discussed in context.</div><div>We introduce the potential role for locoregional therapies (LRTs), including microwave, cryotherapy and therapeutic ultrasound-based treatments as adjunctive treatments for selected cases within the current UK guidelines. We discuss the potential of high intensity focused ultrasound and other LRTs to release sarcoma tumour antigens systemically with the potential to enhance anti-tumour immunity (the ‘abscopal’ effect).</div><div>With increasing indications and availability of locoregional therapies (LRTs) and the first indications of immunotherapy for selected subtypes of STS, potential future directions in functional imaging capability for STS and DT are also discussed.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106969"},"PeriodicalIF":2.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to Editor regarding, “Clinical effect of catheter-directed thrombolysis combined with intermittent pneumatic compression on lower extremity deep venous thrombosis” 致编辑关于“导管溶栓联合间歇气压加压治疗下肢深静脉血栓的临床效果”的信

IF 2.1 3区医学

Clinical radiology Pub Date : 2025-05-23 DOI: 10.1016/j.crad.2025.106972

G. Gambhir

引用次数: 0

High-risk breast cancer screening with MRI: diagnostic performance of a local scoring system 高危乳腺癌MRI筛查：局部评分系统的诊断性能

IF 2.1 3区医学

Clinical radiology Pub Date : 2025-05-22 DOI: 10.1016/j.crad.2025.106968

K. Ziada, M. Siu, R. Gatt, N. Jallad, N. Hartley, G. McDonald, M. Al-Attar

{"title":"High-risk breast cancer screening with MRI: diagnostic performance of a local scoring system","authors":"K. Ziada, M. Siu, R. Gatt, N. Jallad, N. Hartley, G. McDonald, M. Al-Attar","doi":"10.1016/j.crad.2025.106968","DOIUrl":"10.1016/j.crad.2025.106968","url":null,"abstract":"<div><h3>Aim</h3><div>Breast MRI is widely used for screening high-risk women, though its high cost and false positive rates pose challenges. There is growing research exploring the potential integration of breast MRI into the screening of other patient groups, including women with dense breasts and/or an intermediate lifetime risk for breast cancer. We evaluated the diagnostic performance of Leicester scoring system (LSS) in managing lesions detected at high-risk screening breast MRI.</div></div><div><h3>Materials and Methods</h3><div>In this retrospective study, 73 lesions from 174 high-risk breast MRI studies over a 10-year period (2014–2024) were analyzed. Included lesions were masses, foci, and linear/ductal non–mass-like enhancement. Lesions were classified and scored using the LSS, which combines five MRI descriptors: margins, signal patterns, internal enhancement, contrast kinetics, and DWI patterns.</div></div><div><h3>Results</h3><div>All 10 malignant lesions had LSS scores ≥2 (mean: 4.6). Of the 40 benign lesions (excluding IMLNs), 87.5% had scores <2 (mean: 1.1). The optimal cut-off of 2 achieved 100% sensitivity and 87.5% specificity (<em>p</em><0.001). Typical IMLNs, which often mimic malignancy on imaging, should be excluded from scoring and considered benign when they are not significant by size criteria. Using LSS could potentially avoid biopsy in 48% of lesions, or up to 79% if IMLNs are excluded, without missing any cancers. The inter-reader agreement was very good, with a K-value of 0.81 (<em>p</em><0.001).</div></div><div><h3>Conclusion</h3><div>Leicester Scoring System has the potential to avoid up to 79% of unnecessary biopsies without compromising cancer detection. Our results challenge the assumption that cancers may present with exclusively benign features in this cohort of women.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106968"},"PeriodicalIF":2.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144307136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MRI-based radiomics model for the preoperative prediction of classification in children with venous malformations 基于mri放射组学模型的儿童静脉畸形术前分类预测

IF 2.1 3区医学

Clinical radiology Pub Date : 2025-05-22 DOI: 10.1016/j.crad.2025.106966

B. Jiao, L. Wang, X. Zhang, Y. Niu, J. Li, Z. Liu, D. Song, L. Guo

{"title":"MRI-based radiomics model for the preoperative prediction of classification in children with venous malformations","authors":"B. Jiao, L. Wang, X. Zhang, Y. Niu, J. Li, Z. Liu, D. Song, L. Guo","doi":"10.1016/j.crad.2025.106966","DOIUrl":"10.1016/j.crad.2025.106966","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to explore the efficacy of MRI-based radiomics models, employing various machine learning techniques, in the preoperative prediction of the digital subtraction angiography (DSA) classification of venous malformations (VMs).</div></div><div><h3>Materials and methods</h3><div>In this retrospective study, 160 VM lesions from 153 children were categorized into a training set (n=128) and a testing set (n=32). Radiomic features were extracted from preoperative MRI scans. Feature selection was executed using the intraclass correlation coefficient test, z-scores, the K-best method, and the least absolute shrinkage and selection operator. Diverse MRI sequences and machine learning methods underpinned the development of the radiomics models. The models' efficacy was evaluated using receiver operating characteristic curves and the area under the curve (AUC).</div></div><div><h3>Results</h3><div>Out of 4528 radiomic features derived from CET1 and T2 images, 9 features were significantly associated with DSA classification differentiation. The most effective model for predicting VMs' DSA classification incorporated these 9 features and employed a random forest classifier. This model achieved an AUC of 0.917 in the training set and an excellent discrimination AUC of 0.891 in the testing set.</div></div><div><h3>Conclusion</h3><div>The random forest model, utilizing CET1 and T2 sequences, exhibited outstanding predictive performance in the preoperative distinction of VMs' DSA classification.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106966"},"PeriodicalIF":2.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of the junior doctors’ industrial action on the efficiency of a radiology department 初级医生工业行动对放射科工作效率的影响

IF 2.1 3区医学

Clinical radiology Pub Date : 2025-05-22 DOI: 10.1016/j.crad.2025.106965

Isobel Saoirse Kelsh

引用次数: 0