Clinical radiology最新文献

{"title":"Open- source computed tomography (CT)-based sarcopenia assessment in women with suspicious adnexal masses: a feasibility and reproducibility study","authors":"P.M. Badran ,&nbsp;C.M. Stecca ,&nbsp;J.T. de Souza de Castro ,&nbsp;H. de Jesus Ferreira ,&nbsp;R.M. Jales","doi":"10.1016/j.crad.2025.107088","DOIUrl":"10.1016/j.crad.2025.107088","url":null,"abstract":"<div><h3>Aim</h3><div>Ovarian cancer is the most lethal gynecologic malignancy, with prognosis linked to stage at diagnosis. Ultrasonography is the first-line tool for adnexal mass evaluation, while computed tomography (CT) supports staging and surgical planning. Sarcopenia—low skeletal muscle mass—is a prognostic factor in oncology and measurable on routine CT. Its role in women with indeterminate or malignant adnexal masses remains unclear. This study aimed to assess the feasibility, reproducibility, and clinical utility of CT-based sarcopenia analysis using open-source software in this population.</div></div><div><h3>Materials and Methods</h3><div>In this prospective pilot study, 38 women with suspicious adnexal masses (classified as indeterminate or malignant by International Ovarian Tumor Analysis Simple Rules, Ovarian-Adnexal Reporting and Data System, or subjective assessment) underwent CT-based sarcopenia analysis. Axial CT images at the L3 level were segmented using 3D Slicer. Skeletal muscle index (SMI, cm²/m²) was calculated, with sarcopenia defined as SMI &lt;38.5 cm²/m². Interobserver agreement was evaluated with Bland–Altman plots and Cohen’s kappa. Associations were tested using chi-square, and diagnostic performance for malignancy prediction was assessed by sensitivity, specificity, predictive values, likelihood ratios, and area under the receiver operating characteristic curve.</div></div><div><h3>Results</h3><div>Sarcopenia analysis was feasible and reproducible (κ = 0.839). Significant associations were observed with advanced tumor stage (P = .028) and peritoneal carcinomatosis (P = .033), but not with histopathological malignancy, lymphadenopathy, adjacent invasion, or suspicion of alternative primary tumor. Diagnostic performance for malignancy prediction was limited.</div></div><div><h3>Conclusion</h3><div>CT-based sarcopenia analysis using open-source software is feasible and reproducible. Although associated with advanced disease, sarcopenia did not enhance malignancy prediction and should not guide preoperative risk stratification. Its potential value may lie in identifying patients who could benefit from prehabilitation or targeted nutritional support before treatment.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"91 ","pages":"Article 107088"},"PeriodicalIF":1.9,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145265167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatic and pericardial fat in coronary computed tomography angiography and its association with coronary artery disease","authors":"O. Konukoglu,&nbsp;M. Kaya,&nbsp;C. Gungor,&nbsp;B.C. Arslan","doi":"10.1016/j.crad.2025.107080","DOIUrl":"10.1016/j.crad.2025.107080","url":null,"abstract":"<div><h3>AIM</h3><div>The aim of this study was to evaluate the association of both hepatosteatosis and epicardial adipose tissue (EAT) and paracardial adipose tissue (PAT) with coronary artery disease (CAD).</div></div><div><h3>MATERIALS AND METHODS</h3><div>The coronary computed tomography angiography (CCTA) images of 331 consecutive patients were retrospectively analysed. Epicardial and paracardial fat areas and hepatic attenuation values were measured on the same images. The presence and severity of coronary artery stenosis were assessed, and the coronary calcium burden was calculated.</div></div><div><h3>RESULTS</h3><div>No correlation was observed between the presence or severity of CAD and steatosis in either group. However, the proportion of patients with moderate and severe calcium scores was significantly higher in the steatosis group (<em>P</em>=0.016). EAT and PAT values were statistically significantly higher in the steatosis group than in the nonsteatosis group across both readers (<em>P</em>&lt;0.05). Similarly, in patients with CAD, EAT and PAT values were statistically significantly higher than in those without CAD across both readers (<em>P</em>&lt;0.05). The logistic regression analysis showed that PAT measurements significantly differed between individuals with and without CAD, with consistent results from both readers.</div></div><div><h3>CONCLUSION</h3><div>EAT and PAT values may be considered more useful than hepatosteatosis in assessing the risk of CAD. These parameters could serve as independent markers for determining the presence and severity of CAD.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"91 ","pages":"Article 107080"},"PeriodicalIF":1.9,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145264193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artefacts in contrast-enhanced mammography and their clinical management","authors":"D.E. Tekcan Sanli ,&nbsp;A.N. Sanli","doi":"10.1016/j.crad.2025.107084","DOIUrl":"10.1016/j.crad.2025.107084","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"91 ","pages":"Article 107084"},"PeriodicalIF":1.9,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145264247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"British Society of Urogenital Radiology (BSUR) commentary: agreement criteria for expert-level reporting during the prostate magnetic resonance imaging (MRI) learning curve","authors":"T. Barrett ,&nbsp;S.J. Withey ,&nbsp;I. Caglic","doi":"10.1016/j.crad.2025.107082","DOIUrl":"10.1016/j.crad.2025.107082","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"91 ","pages":"Article 107082"},"PeriodicalIF":1.9,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145265169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and sonographic factors influencing diagnostic yield of ultrasound-guided core biopsy of cervical lymph nodes","authors":"A. Yahav-Dovrat ,&nbsp;M. Saban ,&nbsp;G. Merhav ,&nbsp;N. Beck Razi","doi":"10.1016/j.crad.2025.107093","DOIUrl":"10.1016/j.crad.2025.107093","url":null,"abstract":"<div><h3>AIM</h3><div>Cervical lymphadenopathy can indicate various benign or malignant conditions. While ultrasound-guided core biopsy is commonly used for diagnosis, its effectiveness can vary. Our study aimed to determine factors that affect the diagnostic yield of this procedure, potentially guiding appropriate patient referrals towards either more invasive diagnostic procedures, such as open biopsy or less intensive approaches like ongoing follow-up.</div></div><div><h3>MATERIALS AND METHODS</h3><div>A retrospective study was conducted evaluating ultrasound-guided core biopsies performed for cervical lymphadenopathy at a single institution. Imaging features and technical details were documented. Two radiologists collected data from formal procedure reports and recorded sonographic images. Data were then correlated with histopathologic reports.</div></div><div><h3>RESULTS</h3><div>The study included 136 patients with final diagnoses of lymphoproliferative disease (95 patients, 69.8%), reactive lymphadenopathy (24 patients, 17.6%), and carcinoma (17 patients, 12.5%). Twenty-four of the initial biopsies were nondiagnostic (17.6%), requiring diagnosis through surgery, follow-up, or repeated biopsy. Of the 24 nondiagnostic biopsies, 17 were eventually identified as reactive lymph nodes, and 7 harboured lymphoproliferative disease. All carcinoma cases were detected on the initial biopsy.</div><div>Larger lymph node size correlated with higher diagnostic yield (<em>P</em> &lt; 0.01). No correlation was found with needle gauge (<em>P</em> = 0.13), proximity to large vessels (<em>P</em> = 0.68), or overshoot potential (<em>P</em> = 0.26).</div></div><div><h3>CONCLUSION</h3><div>Our study results show that smaller lymph node size and the presence of a fatty hilum are correlated with reduced diagnostic yield. Patients with unfavourable characteristics should be considered for imaging surveillance, fine-needle aspiration (FNA), or an open biopsy.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"91 ","pages":"Article 107093"},"PeriodicalIF":1.9,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145291430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"JBREAS code for incidental breast lesions","authors":"D.E. Tekcan Sanli ,&nbsp;A.N. Sanli","doi":"10.1016/j.crad.2025.107089","DOIUrl":"10.1016/j.crad.2025.107089","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"91 ","pages":"Article 107089"},"PeriodicalIF":1.9,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145264248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT and MRI activity in England: insights from the diagnostic imaging dataset.","authors":"R Swann, S Dixon, K Roberts, S Black, K Memon, F Fardus-Reid, L Ironmonger, G Maskell, J Shelton, M Richards","doi":"10.1016/j.crad.2025.107087","DOIUrl":"https://doi.org/10.1016/j.crad.2025.107087","url":null,"abstract":"<p><strong>Aims: </strong>This study aimed to examine increases and variations in CT and MRI activity in England.</p><p><strong>Materials and methods: </strong>Trends in CT and MRI activity between 2016/17 and 2023/24 were assessed from the Diagnostic Imaging Dataset; measured by source of request (A&E, inpatient, outpatient and GP direct access), body part, age, gender and integrated care board (ICB). Trust imaging activity by the number of scanners was assessed using the National Imaging Data Collection.</p><p><strong>Results: </strong>CT activity increased by 60% (average 6% p.a.) and MRI by 31% (3% p.a.). Apart from the first year of the pandemic, increases over time were observed in all subgroups analysed. Particular increases were observed in the use of CT head/torso, angiographic procedures and whole body. Outpatient requests accounted for the largest number of MRI scans (63%) with A&E/inpatients and GP direct access each accounting for around 16%. MRI of the head accounted for 25% of all MRI activity in 2023/24, with MRI of the spine (26%) and MRI of limbs (16%). However, MRI of the whole body, prostate and radiotherapy planning accounted for the largest proportional increases over time. Major variations were observed between ICBs both for CT and MRI, with the widest variations being for patients referred through GP direct access. Wide variations in activity were seen between trusts with the same number of CT and MRI scanners.</p><p><strong>Conclusions: </strong>These analyses could contribute to assessments of likely future demand on services and supporting ICBs and trusts in benchmarking activity.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":" ","pages":"107087"},"PeriodicalIF":1.9,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145274057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial on computed tomography (CT) and magnetic resonance imaging (MRI) activity in England: insights from the diagnostic imaging dataset.","authors":"S P Harden, H C Addley, R D Proctor","doi":"10.1016/j.crad.2025.107086","DOIUrl":"https://doi.org/10.1016/j.crad.2025.107086","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":" ","pages":"107086"},"PeriodicalIF":1.9,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145312540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A computed tomography (CT)-based ternary classification model for predicting the invasiveness of pure ground-glass nodules","authors":"Y. Gao ,&nbsp;C. Yan ,&nbsp;Z. Cao ,&nbsp;Z. Xie ,&nbsp;H. Shi ,&nbsp;D. Yang ,&nbsp;J. Wang","doi":"10.1016/j.crad.2025.107081","DOIUrl":"10.1016/j.crad.2025.107081","url":null,"abstract":"<div><h3>OBJECTIVE</h3><div>To develop and validate a multinomial logistic regression model utilising computed tomography (CT) features for the classification of the invasiveness of pulmonary pure ground-glass nodules (pGGNs).</div></div><div><h3>MATERIALS AND METHODS</h3><div>This retrospective study involved 1572 pathologically confirmed cases of pGGNs, which included atypical adenomatous hyperplasia (AAH), adenocarcinoma <em>in situ</em> (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IAC). These cases were categorised into three groups based on invasiveness: precursor glandular lesions (PGLs, AAH + AIS), MIA, and IAC. The cohort was randomly divided into training (70%), testing (15%), and validation (15%) sets using stratified sampling. Univariate and multivariate analyses were conducted to identify candidate predictors, and L1-regularised (Lasso) feature selection was employed to reduce dimensionality. Subsequently, a multinomial logistic regression model was constructed. The model’s performance was evaluated using the area under the receiver operating characteristic curve (AUC), sensitivity, and specificity in both the testing and validation sets.</div></div><div><h3>RESULTS</h3><div>The mean patient age was 54.9 ± 12.6 years, with 32.4% being male. Seventeen features were identified as significant predictors following Lasso selection. In the testing set, the overall macro-average AUC was 0.793 (95% CI: 0.731-0.853), with a sensitivity of 0.564 and specificity of 0.789. In the validation set, the macro-average AUC was 0.764 (95% CI: 0.696-0.827), with a sensitivity of 0.589 and specificity of 0.803.</div></div><div><h3>CONCLUSION</h3><div>The proposed CT-based multinomial logistic regression model effectively stratifies pGGNs by invasiveness, providing a noninvasive tool to guide personalised management and enhance preoperative decision-making.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"90 ","pages":"Article 107081"},"PeriodicalIF":1.9,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145217581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of balanced steady-state free precession for portosystemic shunts prior to balloon-occluded retrograde transvenous obliteration","authors":"K. Matsushita ,&nbsp;K. Kageyama ,&nbsp;A. Yamamoto ,&nbsp;A. Jogo ,&nbsp;S. Harada ,&nbsp;K. Murai ,&nbsp;M. Nakano ,&nbsp;D. Takemori ,&nbsp;T. Norimasa ,&nbsp;Y. Miki","doi":"10.1016/j.crad.2025.107083","DOIUrl":"10.1016/j.crad.2025.107083","url":null,"abstract":"<div><h3>AIM</h3><div>This study visualised portosystemic shunts (PSSs), referring to gastrorenal or splenorenal shunts, on balanced steady-state free precession (bSSFP) imaging and assessed its accuracy compared with contrast-enhanced computed tomography (CECT).</div></div><div><h3>MATERIALS AND METHODS</h3><div>Patients with bSSFP and CECT imaging of a PSS prior to balloon-occluded retrograde transvenous obliteration from March 2017 to September 2021 were included. The quality of both images was graded based on whether the entire PSS pathway from the afferent vein to the efferent vein was traceable as “well-visualised,” “poorly visualised,” or “not visualised.” Factors contributing to well-visualised on bSSFP images were investigated, including sex, age, height, weight, diagnosis (gastric varices or hepatic encephalopathy), type of PSS, maximum short-axis diameter of the PSS, signal intensity of the surrounding tissue around the PSS, and motion artifacts. Visualisation of collateral drainage veins of the PSS was also evaluated.</div></div><div><h3>RESULTS</h3><div>Ten of 22 cases were graded well-visualised, 9 poorly visualised, and 3 not visualised on bSSFP images, whereas all cases were graded well-visualised on CECT. There was a significant difference between the two imaging modalities for well-visualised images (<em>P</em>&lt;.001). Univariate analyses identified signal intensity of the surrounding tissue around the PSS and motion artifacts as factors contributing to well-visualised on bSSFP images (both <em>P</em>&lt;.05). Multivariate analysis also showed that the former factor contributed to well-visualised images (<em>P</em>&lt;.001). Of 30 collateral veins visualised on balloon-occluded retrograde transvenous venography , 13 were seen on bSSFP and 20 on CECT.</div></div><div><h3>CONCLUSION</h3><div>Though bSSFP imaging is a potential alternative for visualising PSS, it is less effective than contrast-enhanced computed tomography.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"91 ","pages":"Article 107083"},"PeriodicalIF":1.9,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}