Clinical radiology最新文献

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SCOUT® radar reflectors for impalpable lesion localisation in the breast and axilla: our experience in the first 500 patients.
IF 2.1 3区 医学
Clinical radiology Pub Date : 2024-12-12 DOI: 10.1016/j.crad.2024.106777
S Siddiqui, M Povey, M Rowland, S Sharma
{"title":"SCOUT® radar reflectors for impalpable lesion localisation in the breast and axilla: our experience in the first 500 patients.","authors":"S Siddiqui, M Povey, M Rowland, S Sharma","doi":"10.1016/j.crad.2024.106777","DOIUrl":"https://doi.org/10.1016/j.crad.2024.106777","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to detail our experience of using SCOUT® radar reflector for lesion localisation in the breast and axilla.</p><p><strong>Materials and methods: </strong>This is a prospective cohort study describing our clinical experience with the first 500 patients who received SCOUT® to localise lesions in the breast and axilla (from 23 July 2020 to 4 April 2022). Study measures include patient demographics, lesion location, diagnostic pathways (screening or symptomatic), imaging, and surgical and pathology outcomes.</p><p><strong>Results: </strong>Of the 500 patients, most patients (n = 424; 84.8%) had a single device inserted. A total of 361 had SCOUT® inserted under ultrasound guidance, 128 under stereotactic guidance, and 11 under dual mammographic and ultrasonographic guidance. We successfully inserted SCOUT® in 33 patients for lymph node identification for potential targeted axillary dissection. The mean time between SCOUT® insertion and the planned surgical procedure was 40.6 days.</p><p><strong>Conclusion: </strong>Our results suggest that SCOUT® is a promising preoperative localisation device for nonpalpable breast and axillary lesions. Its implementation has the potential to optimise the clinical workflow by eliminating the need for a separate localisation procedure using conventional localisation markers and streamlining the treatment pathway.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"106777"},"PeriodicalIF":2.1,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthetic diffusion-weighted imaging in prostate cancer diagnosis: a comparison study with different B-value combinations.
IF 2.1 3区 医学
Clinical radiology Pub Date : 2024-12-07 DOI: 10.1016/j.crad.2024.106770
L He, Z Zhang, J Zhang, J Xia, Y Wang, J Zhu
{"title":"Synthetic diffusion-weighted imaging in prostate cancer diagnosis: a comparison study with different B-value combinations.","authors":"L He, Z Zhang, J Zhang, J Xia, Y Wang, J Zhu","doi":"10.1016/j.crad.2024.106770","DOIUrl":"https://doi.org/10.1016/j.crad.2024.106770","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the impact of different b-value combinations on synthetic diffusion-weighted imaging (sDWI) and determine the sDWI with an optimal b-value combination for prostatic cancer (PCa) diagnosis.</p><p><strong>Material and methods: </strong>A retrospective analysis of 68 patients with abnormal prostate-specific antigen (PSA) was conducted. The sDWI images with b value of 1500 s/mm<sup>2</sup> were separately reconstructed by the following five b-value combinations: b=0, 200s/mm<sup>2</sup> (sDWI<sub>0-200</sub>); b=600, 800s/mm<sup>2</sup> (sDWI<sub>600-800</sub>); b=0, 600s/mm<sup>2</sup> (sDWI<sub>0-600</sub>); b=200, 800s/mm<sup>2</sup> sDWI<sub>200-800</sub>); b=0, 800s/mm<sup>2</sup> (sDWI<sub>0-800</sub>). Quantitative analysis was performed on the acquired DWI (aDWI) images with b=1500s/mm<sup>2</sup> (aDWI<sub>1500</sub>) and all sDWI images. These six image groups were scored in five aspects for image quality and further reviewed by two radiologists via six protocols: Protocol Ⅰ, T<sub>2</sub>WI+sDWI<sub>0-200</sub>; Protocol Ⅱ, T<sub>2</sub>WI+sDWI<sub>600-800</sub>; Protocol Ⅲ, T<sub>2</sub>WI+sDWI<sub>0-600</sub>; Protocol Ⅳ, T<sub>2</sub>WI+sDWI<sub>200-800</sub>; Protocol Ⅴ, T<sub>2</sub>WI+sDWI<sub>0-800</sub>; Protocol Ⅵ, T<sub>2</sub>WI+aDWI<sub>1500</sub>. The corresponding diagnostic efficacies for PCa were evaluated using receiver operating characteristic (ROC) curves.</p><p><strong>Results: </strong>Contrast ratio values of all sDWI images were higher than those of aDWI<sub>1500</sub> images. Contrast-to-noise ratio values of sDWI<sub>0-200</sub> and sDWI<sub>600-800</sub> images were lower than those of the rest sDWI images. All subjective quality scores of sDWI<sub>0-600</sub>, sDWI<sub>200-800,</sub> and sDWI<sub>0-800</sub> were significantly higher than other groups except for background signal suppression. The area under the curve (AUC) of Protocol Ⅲ, Ⅳ, Ⅴ, and Ⅵ was significantly larger than those of other protocols.</p><p><strong>Conclusion: </strong>Different b-value combinations impact the image quality and diagnostic accuracy of sDWI for PCa detection. The combination of b≤200s/mm<sup>2</sup> and b≥600s/mm<sup>2</sup> revealed to be optimal.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"106770"},"PeriodicalIF":2.1,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating the challenges in radiology training expansion: costs and benefits.
IF 2.1 3区 医学
Clinical radiology Pub Date : 2024-12-06 DOI: 10.1016/j.crad.2024.106767
R S Oeppen, H Rafiee, P Suresh, A Rajesh, A Parekh
{"title":"Navigating the challenges in radiology training expansion: costs and benefits.","authors":"R S Oeppen, H Rafiee, P Suresh, A Rajesh, A Parekh","doi":"10.1016/j.crad.2024.106767","DOIUrl":"https://doi.org/10.1016/j.crad.2024.106767","url":null,"abstract":"<p><p>Clinical and interventional radiology services play a vital role in the provision of modern healthcare, but there is a widening gap between the capacity of the imaging workforce and increasing demand. In recent years there has been a programme of training expansion in England supported by tariff level funding from NHS England (Workforce Training and Education Directorate), enhancing long-term radiology workforce sustainability and bringing quality benefits for patients, departments, and trusts. Expansion is a multifaceted and challenging process in the current NHS climate, involving coordination of funding, capacity, and sustained educational quality. These challenges need to be overcome through collaborative working by NHS England, local NHS trusts, and the Royal College of Radiologists.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"106767"},"PeriodicalIF":2.1,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exercise electrocardiogram combined with cadmium zinc tellurium (CZT) cardiac-dedicated single photon emission computed tomography (SPECT) predicts coronary artery disease.
IF 2.1 3区 医学
Clinical radiology Pub Date : 2024-12-05 DOI: 10.1016/j.crad.2024.106769
M Wu, Z Xu, Q Huang, J Shi, K Zhou, Y Hong, Y Zhan, N Zhou
{"title":"Exercise electrocardiogram combined with cadmium zinc tellurium (CZT) cardiac-dedicated single photon emission computed tomography (SPECT) predicts coronary artery disease.","authors":"M Wu, Z Xu, Q Huang, J Shi, K Zhou, Y Hong, Y Zhan, N Zhou","doi":"10.1016/j.crad.2024.106769","DOIUrl":"https://doi.org/10.1016/j.crad.2024.106769","url":null,"abstract":"<p><strong>Aim: </strong>Coronary artery disease (CAD) is a primary cause of mortality, prompting ongoing research into noninvasive diagnostic modalities. This study aimed to evaluate the diagnostic efficacy of exercise electrocardiography testing (EET) combined with cadmium zinc tellurium cardiac-dedicated single photon emission computed tomography (CZT-SPECT) imaging for CAD.</p><p><strong>Materials and methods: </strong>CZT-SPECT and EET were examined in 124 patients aged 20-85 years, followed by coronary angiography to evaluate the sensitivity, specificity, positive predictive value, and negative predictive value of EET/CZT-SPECT alone and in combination. CAD was defined as the presence of > 50% stenosis at the time of coronary angiography.</p><p><strong>Results: </strong>The sensitivity of the EET test alone was 31.58%, the specificity was 80%, the positive predictive value (PPV) was 22.22%, and the negative predictive value (NPV) was 86.6%. The corresponding values of CZT-SPECT alone were 36.07%, 92.06%, 81.48% and 59.79%, respectively. The combined results showed that the sensitivity, specificity, PPV, and NPV were 60.00%, 90.57%, 54.55%, and 92.31%, respectively. In this study, the positive likelihood ratio (PLR) diagnosed with EET alone was 1.58, the PLR diagnosed with CZT-SPECT alone was 4.54, and the PLR diagnosed with combination was 6.36.</p><p><strong>Conclusion: </strong>The combination of CZT-SPECT and EET showed significantly improved CAD diagnostic accuracy compared with either approach alone.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"106769"},"PeriodicalIF":2.1,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamic CT-perfusion parameters as indicators of microcirculation: investigation in patients without obstructive coronary artery disease. 作为微循环指标的动态 CT 灌注参数:对无阻塞性冠状动脉疾病患者的研究。
IF 2.1 3区 医学
Clinical radiology Pub Date : 2024-12-05 DOI: 10.1016/j.crad.2024.106766
M Takafuji, K Kitagawa, M Ishida, M Kubooka, S Nakamura, M Fujita, E Nakamura, S Okabe, K Kawabe, H Sakuma
{"title":"Dynamic CT-perfusion parameters as indicators of microcirculation: investigation in patients without obstructive coronary artery disease.","authors":"M Takafuji, K Kitagawa, M Ishida, M Kubooka, S Nakamura, M Fujita, E Nakamura, S Okabe, K Kawabe, H Sakuma","doi":"10.1016/j.crad.2024.106766","DOIUrl":"https://doi.org/10.1016/j.crad.2024.106766","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the relationship between each CTP parameter and that between CTP parameters and patient characteristics in patients without obstructive coronary artery disease (CAD).</p><p><strong>Materials and methods: </strong>Seventy-seven (28 female; 65.0±10.3 years) patients with suspected CAD who underwent coronary CT angiography (CCTA) and dynamic CTP with vasodilator stress were included. Patients with obstructive coronary stenosis (≥50%) on CCTA were excluded. Myocardial blood flow (MBF) and myocardial blood volume (MBV) were calculated using the slope and peak of the time-attenuation curves of the myocardium and blood. Perfused capillary blood volume (PCBV), extravascular extracellular volume (EEV), and flow extraction product (FE) were calculated using the extended Tofts model.</p><p><strong>Results: </strong>MBF, MBV, and PCBV were strongly correlated with each other (all r > 0.80 and all p < 0.001), whereas FE and EEV were strongly correlated with each other (r = 0.88 and p < 0.001). In univariate linear regression analysis, male sex and smoking status were significantly associated with MBF, MBV, and PCBV, while age was significantly associated with FE and EEV (all p < 0.05). In stepwise multivariate analysis, smoking status was independently associated with MBF, MBV. and PCBV, while age was the only factor associated with FE and EEV (all p < 0.05).</p><p><strong>Conclusion: </strong>FE and EEV may reflect different mechanisms of microvascular dysfunction than MBF, MBV, and PCBV.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"106766"},"PeriodicalIF":2.1,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Centrilobular nodules are predictive chest computed tomography (CT) findings related to adult T-cell leukemia/lymphoma development in human T-lymphotropic virus type I carriers.
IF 2.1 3区 医学
Clinical radiology Pub Date : 2024-12-04 DOI: 10.1016/j.crad.2024.106765
H Sato, F Okada, Y Asayama, M Ogata, K Takano, E Ohtsuka
{"title":"Centrilobular nodules are predictive chest computed tomography (CT) findings related to adult T-cell leukemia/lymphoma development in human T-lymphotropic virus type I carriers.","authors":"H Sato, F Okada, Y Asayama, M Ogata, K Takano, E Ohtsuka","doi":"10.1016/j.crad.2024.106765","DOIUrl":"https://doi.org/10.1016/j.crad.2024.106765","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate predictive chest computed tomography (CT) findings associated with the development of adult T-cell leukemia/lymphoma (ATLL) in human T-lymphotropic virus type I (HTLV-1) carriers.</p><p><strong>Materials and methods: </strong>This retrospective study examined 171 adult T-cell leukemia/lymphoma and 158 HTLV-1 carriers who were treated from November 2004 to April 2021. The radiological features of 888 chest CT scans in total were retrospectively assessed by two chest radiologists who were unaware of the underlying diagnoses and compared between the groups.</p><p><strong>Results: </strong>In patients with aggressive type ATLL (acute type and lymphoma type), lymph node enlargement was the most frequently observed abnormality (65.2%), followed by ground-glass opacity (33.3%) and pleural effusion (30.4%). In patients with indolent type (chronic type and smoldering type), lymph node enlargement, and bronchiectasis were the most frequently observed abnormalities (5.6% and 5.6%, respectively). In each type, centrilobular nodules were observed in none and in one patient, respectively. In the 158 HTLV-1 carriers, centrilobular nodules (n = 62; 39.2%) were the most frequently observed abnormality. Centrilobular nodules were significantly frequently observed in HTLV-1 carriers compared with ATLL patients. No HTLV-1 carrier with centrilobular nodules on CT developed ATLL during the duration of care. A comparative analysis between CT scans performed before ATLL development in ATLL patients and those of HTLV-1 carriers showed that no centrilobular nodules were observed on the pre-ATLL CT scans, and a statistically-significant difference in centrilobular nodules was found between these two groups.</p><p><strong>Conclusion: </strong>The presence of centrilobular nodules may be an indicative CT finding in HTLV-1 carriers who are less likely to develop ATLL.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"106765"},"PeriodicalIF":2.1,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative prognostic prediction for invasive pulmonary adenocarcinoma: Impact of 18F-FDG PET/CT semi-quantitative parameters associated with new histological subtype classification. 浸润性肺腺癌术前预后预测:与新组织学亚型分类相关的 18F-FDG PET/CT 半定量参数的影响。
IF 2.1 3区 医学
Clinical radiology Pub Date : 2024-12-01 Epub Date: 2024-09-04 DOI: 10.1016/j.crad.2024.08.034
K Wang, N Tu, H Feng, Y Zhou, L Bu
{"title":"Preoperative prognostic prediction for invasive pulmonary adenocarcinoma: Impact of <sup>18</sup>F-FDG PET/CT semi-quantitative parameters associated with new histological subtype classification.","authors":"K Wang, N Tu, H Feng, Y Zhou, L Bu","doi":"10.1016/j.crad.2024.08.034","DOIUrl":"10.1016/j.crad.2024.08.034","url":null,"abstract":"<p><strong>Aims: </strong>To explore the preoperative predictive value of <sup>18</sup>F-FDG PET/CT for poor prognostic histologic subtypes of invasive pulmonary adenocarcinoma (IPA) under new classification.</p><p><strong>Materials and methods: </strong>This study included 316 patients. Histopathology of IPA was evaluated by recording the percentage of each histologic component. PET/CT parameters were compared among IPAs with different risks of recurrence. Optimum cutoff values of PET/CT parameters were calculated using ROC curve analysis. Overall survival (OS) and disease-free survival (DFS) were calculated using Kaplan-Meier method, and survival differences between groups were tested using log-rank test. Multivariate analysis for survival was performed using the Cox regression model.</p><p><strong>Results: </strong>Patients were divided into low (LRR), intermediate (IRR), and modified high (mHRR) risk of recurrence group incorporating typical (HRR-T) and nontypical (HRR-NT) subgroups based on histologic patterns. There were significant differences in SUV<sub>max</sub>, SUV<sub>mean</sub>, SUV<sub>min</sub>, SUV<sub>SD</sub>, TLG, and tumor size among three groups. HRR-NT had lower SUV<sub>max</sub>, SUV<sub>mean</sub>, SUV<sub>min</sub>, SUV<sub>SD</sub> and TLG than HRR-T subgroup, and higher SUV<sub>max</sub>, SUV<sub>mean</sub>, SUV<sub>min</sub>, SUV<sub>SD</sub>, MTV, TLG and tumor size than IRR group. ROC curve analysis showed that SUV<sub>max</sub> had highest AUC (0.815) in distinguishing LRR and IRR. TLG had highest AUC (0.741) in distinguishing IRR and mHRR. Multivariable analysis showed that tumor size and SUV<sub>max</sub> were independent predictors of DFS and OS.</p><p><strong>Conclusions: </strong>High risk of recurrence of IPA exhibited higher <sup>18</sup>F-FDG uptake and tumor size. Tumor size and SUV<sub>max</sub> could be used as preoperative surrogates for the IASLC grading system. <sup>18</sup>F-FDG PET/CT can improve the preoperative prognostic prediction for IPA patients.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":" ","pages":"e1539-e1548"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of an automated report comparison tool on trainee report modification rate at a tertiary hospital. 自动报告比较工具对一家三级医院学员报告修改率的影响。
IF 2.1 3区 医学
Clinical radiology Pub Date : 2024-12-01 Epub Date: 2024-09-06 DOI: 10.1016/j.crad.2024.09.001
M J Stewart, R P Lim, J Feldman, N Yang
{"title":"Impact of an automated report comparison tool on trainee report modification rate at a tertiary hospital.","authors":"M J Stewart, R P Lim, J Feldman, N Yang","doi":"10.1016/j.crad.2024.09.001","DOIUrl":"10.1016/j.crad.2024.09.001","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to compare trainee-modified report percentage rate and trainee/consultant satisfaction regarding the feedback process before and after implementation of an automated report comparison tool.</p><p><strong>Materials and methods: </strong>An automated report comparison tool utilising natural language processing, presenting the trainee's preliminary report beside the final consultant report with changes highlighted, was used in a prospective interventional study. Modification rates, including character counts, of co-authored computed tomography (CT) studies were recorded before and after tool implementation over two 6-month periods and compared with Student's t-test. Trainees and consultants were surveyed before and after the interventional period for time spent and feedback satisfaction.</p><p><strong>Results: </strong>In total, 3851 (81.7%) of 4175 reports were modified in the baseline preimplementation phase, and 5215 (69.6%) of 7489 reports were modified during the postimplementation phase (p < .001). The average character count change preimplementation was 132, corresponding to 9.0% of the original preliminary report, compared with 91 characters and 7.1% postimplementation, respectively (p < .001). This statistically significant difference generally applied regardless of the level of trainee experience. Prospective data collected in the preimplementation period revealed that for more than two-thirds of after-hours shifts, trainees spent fewer than 5 minutes receiving feedback on their after-hours work. At the conclusion of the implementation phase, 92.3% of trainees and 70% of consultants agreed that the report comparison tool improved feedback.</p><p><strong>Conclusion: </strong>Following the implementation of an automated report comparison tool, there was a reduction in trainee report modification rates and subjectively improved trainee feedback. This adjunct to existing feedback mechanisms presents a relatively simple intervention to facilitate efficient case review and feedback.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":" ","pages":"e1423-e1432"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of multiple sclerosis lesions by susceptibility-weighted imaging-A systematic review and meta-analyses. 通过感性加权成像检测多发性硬化病变--系统综述和荟萃分析。
IF 2.1 3区 医学
Clinical radiology Pub Date : 2024-12-01 Epub Date: 2024-09-19 DOI: 10.1016/j.crad.2024.09.009
R Afkandeh, I Abedi, M Zamanian
{"title":"Detection of multiple sclerosis lesions by susceptibility-weighted imaging-A systematic review and meta-analyses.","authors":"R Afkandeh, I Abedi, M Zamanian","doi":"10.1016/j.crad.2024.09.009","DOIUrl":"10.1016/j.crad.2024.09.009","url":null,"abstract":"<p><strong>Rationale and objectives: </strong>Susceptibility-weighted imaging (SWI) is a valuable method in the diagnosis of multiple sclerosis (MS). SWI can show diagnostic biomarkers and also distinguish MS lesions from similar diseases. This study is a systematic review and meta-analysis of the available literature to investigate the diagnostic accuracy of SWI for the detection of MS lesions in the brain, while, specific aspects of its performance were examined.</p><p><strong>Material and methods: </strong>Using specified keywords, a search of the electronic databases MEDLINE/PubMed, Scopus, Embase/Elsevier-Ovid, and Scholar databases was conducted. The search time filter ranged from the year 2010 to 2023 . Sensitivity and specificity were used as effect sizes, and SE as a precision metric (with 95% confidence interval). The study was performed according to PRISMA 2020 guidelines and the prospective register of systematic reviews (PROSPERO) registration.</p><p><strong>Results: </strong>The number of 19 studies with a total of 2026 patients to examine both automated and nonautomated assessments. The pooled sensitivities for MS lesion (MSL), paramagnetic rim lesions (PRLs), central vein sign (CVS), and PRL with CVS were 62% (53-72), 37% (17-57), and 60% (31-89). Moreover, the pooled specificities were 93% (90-97), 88% (82-94), 100% (100-100), and 78% (50-100), respectively.</p><p><strong>Conclusion: </strong>Adding the SWI method to routine sequences for MS investigation can provide useful diagnostic information.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":" ","pages":"e1522-e1529"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Access to prior screening mammograms affects the specificity but not sensitivity of radiologists' performance. 获得先前的乳房 X 光筛查结果会影响放射医师工作的特异性,但不会影响灵敏度。
IF 2.1 3区 医学
Clinical radiology Pub Date : 2024-12-01 Epub Date: 2024-09-15 DOI: 10.1016/j.crad.2024.09.007
J D Akwo, P D Yun Trieu, M L Barron, T Reynolds, S J Lewis
{"title":"Access to prior screening mammograms affects the specificity but not sensitivity of radiologists' performance.","authors":"J D Akwo, P D Yun Trieu, M L Barron, T Reynolds, S J Lewis","doi":"10.1016/j.crad.2024.09.007","DOIUrl":"10.1016/j.crad.2024.09.007","url":null,"abstract":"<p><strong>Aims: </strong>To establish the impact that access to prior mammograms has on radiologists' performance and the influence of radiologists' characteristics and breast density on their subsequent performance.</p><p><strong>Methods: </strong>Eight participants independently interpreted 72 digital screening mammograms in two reading sessions using the Royal Australian and New Zealand College of Radiologist's classification. In the first reading session, participants were given access to current and prior mammograms. In the second reading session six months later, participants only had access to the current mammograms. Radiologists' specificity, sensitivity, lesion sensitivity, Receiver Operating Characteristic (ROC) curve, and Jacknife Alternative Free-response ROC (JAFROC) were calculated. A Paired T-test was used to compare readings with and without prior mammograms, and to assess if breast density influenced participants performance. Independent Sample T-test was used to compare performance across radiologists' characteristics. A relative risk analysis was conducted to assess the probability of false positives and false negatives when prior mammograms were available.</p><p><strong>Results: </strong>Access to prior mammograms improved specificity in dense and non-dense breasts (p≤0.01) and reduced false positives (p = 0.01) but had no effect on sensitivity (p = 0.37), lesion sensitivity (p = 0.67), ROC (p = 0.16), and JAFROC (p = 0.24). Prior mammogram also reduced the probability of false positives (RR = 0.38; 95%CI:0.26-0.57, p<0.0001) without affecting the false negative rate (RR = 1.14; 95%CI:0.88-1.49, p = 0.30). The impact of prior mammograms on performance was not influenced by breast density or radiologists' characteristics.</p><p><strong>Conclusions: </strong>Access to prior mammograms improves radiologists' specificity and reduces false positives without affecting sensitivity and the false negative rate regardless of radiologists' characteristics and breast density.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":" ","pages":"e1549-e1556"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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