Clinical radiology最新文献

{"title":"RCR meetings","authors":"","doi":"10.1016/S0009-9260(25)00079-0","DOIUrl":"10.1016/S0009-9260(25)00079-0","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"83 ","pages":"Article 106874"},"PeriodicalIF":2.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paid MBP advert: 250120_Thoracic Imaging-CR-210x280-v2","authors":"","doi":"10.1016/S0009-9260(25)00080-7","DOIUrl":"10.1016/S0009-9260(25)00080-7","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"83 ","pages":"Article 106875"},"PeriodicalIF":2.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One class classification-empowered radiomics for noninvasively accurate prediction of glioma isocitrate dehydrogenase mutation using multiparametric magnetic resonance imaging","authors":"J. Jian ,&nbsp;L. Xu ,&nbsp;C. Gong ,&nbsp;S. Ding ,&nbsp;X. Gong ,&nbsp;X. Yuan ,&nbsp;W. Zheng ,&nbsp;X. Wang ,&nbsp;Y. Zhang","doi":"10.1016/j.crad.2025.106866","DOIUrl":"10.1016/j.crad.2025.106866","url":null,"abstract":"<div><h3>Background</h3><div>Noninvasive detection of isocitrate dehydrogenase (<em>IDH</em>) mutations is crucial for preoperative decision-making in patients with glioma. While radiomics has been applied, data imbalance—specifically between <em>IDH</em> wild-type and mutated genes—remains underexplored. We developed a one-class classification-empowered radiomics (OCCR) model, trained exclusively on <em>IDH</em> wild-type patients, to distinguish them from <em>IDH</em> mutation cases.</div></div><div><h3>Materials and Methods</h3><div>This study included 495 patients from the UCSF Preoperative Diffuse Glioma MRI dataset. T1, T1ce, and FLAIR sequences were registered to T2 and resampled to a 1-mm isotropic resolution. The coregistered data were skull-stripped, and the tumor region was segmented using an ensemble model, followed by manual refinement. We extracted 386 radiomics features from the four MRI sequences and input them into an auto-encoder with 7 hidden layers for reconstruction. The OCCR model was trained on wild-type <em>IDH</em> patients, using the mean square error between the original and reconstructed features as guidance. During validation, reconstruction error was used to differentiate <em>IDH</em> mutations from the wild type.</div></div><div><h3>Results</h3><div>The hold-out validation demonstrated that OCCR performance improved as the number of training samples increased, achieving a peak area under the receiver operating characteristic curve of 0.8018. Visualization of reconstruction errors highlighted first-order and gray-level co-occurrence matrix features in the T1ce sequence.</div></div><div><h3>Conclusions</h3><div>This study demonstrates the feasibility of integrating one-class classification into radiomics for the determination of preoperative <em>IDH</em> mutation status in patients with glioma using multiparametric MRI. This versatile model holds potential for other diseases with substantial data imbalance.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"84 ","pages":"Article 106866"},"PeriodicalIF":2.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143725937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative prediction of muscle invasion in bladder cancer in the Indian population using the Vesical Imaging-Reporting and Data System (VI-RADS) score and individual multiparametric magnetic resonance imaging (MRI) characteristics","authors":"A. Selvaraju ,&nbsp;N.K. Patbamniya ,&nbsp;M. Kumar ,&nbsp;A. Seth ,&nbsp;S. Kaushal ,&nbsp;C.J. Das","doi":"10.1016/j.crad.2025.106862","DOIUrl":"10.1016/j.crad.2025.106862","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to prospectively validate the Vesical Imaging-Reporting and Data System (VI-RADS) score in the preoperative prediction of muscle invasion in bladder cancer in the Indian population.</div></div><div><h3>Materials and Methods</h3><div>The study prospectively reviewed patients with bladder masses who underwent 1.5T multiparametric magnetic resonance imaging between December 2018 and April 2023. Clinical and pathological data were collected, and bladder tumors were evaluated using a 5-point VI-RADS scoring system. Independent measurements of quantitative parameters (maximum tumor diameter [DMax] and tumor contact length [TCL]) were performed. These parameters and VI-RADS scores were compared to postoperative pathology to assess muscle invasion. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated using a cutoff score of 4. Receiver Operating Characteristic (ROC) analysis evaluated the diagnostic performance of quantitative values.</div></div><div><h3>Results</h3><div>A total of 55 patients were included in the analysis, of whom 36 were non–muscle invasive and 19 were muscle invasive on the final histopathological report. A VI-RADS score of ≥4 as the cutoff for muscle invasion yielded a sensitivity and specificity of 94.7% (95% CI 72.7%–99.9%) and 97.2% (95% CI 85%–99.9%), with PPV and NPV value of 94.7% and 97.2%, respectively. The receiver operating curve showed an area under the curve (AUC) of 0.958 (95% CI 0.89-1.0). The AUC of TCL and TCL/DMax values for muscle invasion were 0.811 and 0.835, respectively.</div></div><div><h3>Conclusions</h3><div>The VI-RADS scoring system, qualitative parameters, as well as the TCL and TCL/Dmax exhibits a strong correlation with pathological staging, indicating to be an effective method for the preoperative determination of muscle invasion in bladder cancer.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"84 ","pages":"Article 106862"},"PeriodicalIF":2.1,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143680939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adrenal vein sampling: accuracy of earlier sampling post adrenocorticotropic hormone (ACTH) administration","authors":"Q.X. Tee ,&nbsp;J.C.G. Doery ,&nbsp;A. Desra ,&nbsp;P.J. Fuller ,&nbsp;J. Yang ,&nbsp;K.K. Lau","doi":"10.1016/j.crad.2025.106861","DOIUrl":"10.1016/j.crad.2025.106861","url":null,"abstract":"<div><h3>Aim</h3><div>Multiple studies recommend sampling at least 15-30-minutes post administration of ACTH. The aim of this retrospective study was to determine the impact on adrenal vein sampling (AVS) result interpretation when obtaining post-ACTH blood samples earlier, at 5- and 10-minutes, compared to the standard 15-30 minutes.</div></div><div><h3>Materials and methods</h3><div>All consecutive adult patients who underwent AVS using the simultaneous sampling method between August 2023 and March 2024 were included. The differences in adrenal vein aldosterone and cortisol levels at 5- and 10-minutes were compared to the referenced 15-minute samples.</div></div><div><h3>Results</h3><div>A total of 46 AVS studies were included. On average, there was an 11- and 9-fold increase in the SI between the pre- and post-ACTH samples on the right and left respectively, indicating appropriate adrenal vein cannulation. Most of the percentage differences between the levels of cortisol and aldosterone at 5- and 10-minutes compared to those at 15-minutes were within 1 standard deviation from the median. There was no significant difference in LI or overall lateralisation between the 5-minute (paired t-test <em>P</em> = 0.18) and the 10-minute sample (paired t-test <em>P</em> = 0.61) compared to the 15-minute sample. The LI at 5-minutes and 10 minutes demonstrated strong correlation with that at 15-minutes. There was one exception where the LI of the 5- and 10-minute samples were discordant with the 15-minute sample, but concordant with the pre-ACTH sample.</div></div><div><h3>Conclusion</h3><div>AVS can be a lengthy and technically challenging procedure. Being able to sample much earlier post-ACTH may help improve procedural efficiency, reduce procedural risks and minimize patient discomfort.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"84 ","pages":"Article 106861"},"PeriodicalIF":2.1,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143682069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Roles of triglyceride-glucose index in aortic valve calcification progression: a prospective and Mendelian randomization analysis","authors":"Q.-Y. Hao ,&nbsp;J.-W. Gao ,&nbsp;Y.-H. Zeng ,&nbsp;S.-L. Zhang ,&nbsp;Z.-C. Xiong ,&nbsp;S.-C. Li ,&nbsp;Z.-W. Lin ,&nbsp;P.-Z. Yang ,&nbsp;P.-M. Liu ,&nbsp;Z.-H. Li","doi":"10.1016/j.crad.2025.106860","DOIUrl":"10.1016/j.crad.2025.106860","url":null,"abstract":"<div><h3>Aim</h3><div>The triglyceride-glucose (TyG) index, recognized as a surrogate marker for insulin resistance, is an established cardiovascular risk factor. We aimed to prospectively investigate the association between the TyG index and aortic valve calcific (AVC) progression, as well as its relationship with incident calcific aortic valve stenosis (CAVS).</div></div><div><h3>Materials and Methods</h3><div>A post hoc analysis was conducted on 5589 participants from the Multi-Ethnic Study of Atherosclerosis (MESA) database. The TyG index was calculated using ln (fasting triglycerides [mg/dL] × fasting glucose [mg/dL]/2). Multivariate Cox regression assessed the association between baseline TyG index and AVC progression. Two-sample Mendelian randomization (MR) analysis was employed to evaluate the potential causality between the TyG index and CAVS.</div></div><div><h3>Results</h3><div>Over a median 2.4 years follow up, 567 cases of AVC progression were idenrified. After adjusting for traditional cardiovascular risk factors, each 1-SD increase in the TyG index was associated with a 20.8% increased risk of AVC progression. Robustness was confirmed in sensitivity analyses and nearly all subgroups. Two sample MR analysis supported a causal relationship between a higher TyG index and increased risk of CAVS.</div></div><div><h3>Conclusion</h3><div>A higher TyG index independently predicts AVC progression and causally influences CAVS incidence in the general population.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"84 ","pages":"Article 106860"},"PeriodicalIF":2.1,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143637689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT and MRI findings of intraorbital wooden foreign bodies","authors":"C. Song,&nbsp;J. Li,&nbsp;T. Wang,&nbsp;T. Jiang,&nbsp;M. Zhang,&nbsp;A. Gao,&nbsp;S. Cui,&nbsp;X. Zhao,&nbsp;D. Hao","doi":"10.1016/j.crad.2025.106859","DOIUrl":"10.1016/j.crad.2025.106859","url":null,"abstract":"<div><div>AIM: To characterize the computed tomography (CT) and magnetic resonance imaging (MRI) findings of intraorbital wooden foreign bodies (IOWFB) and to evaluate their diagnostic value.</div></div><div><h3>MATERIALS AND METHODS</h3><div>CT and MRI findings of 10 patients with surgically proven IOWFB were retrospectively examined. The image features of IOWFB assessed included location, geometry, margin, size, attenuation on CT, and signal intensity on MRI.</div></div><div><h3>RESULTS</h3><div>On CT (n=10) and MRI (n=5), the IOWFB appeared as rods in eight cases and as wedges in two cases. All 10 IOWFB exhibited clear margins. The sizes of IOWFB ranged from 8 × 6.4 mm to 46 × 5.5 mm, with a mean of 26.6 × 5.4 mm. Hypoattenuation between the attenuation of fat and air was observed in eight patients (acute stage) with IOWFB, with a mean value of −252.77 HU (Hounsfield Unit) on CT. One of these patients (subacute stage) showed hyperattenuation with a mean value of 97.28 HU above that of extraocular muscle on CT performed 15 days post injury. In two patients (chronic stage), the IOWFB exhibited hyperattenuation on CT and were encapsulated by granulation tissue with attenuation of 79.08 HU and 212.95 HU. On the MRI of all five patients, the IOWFB showed hypointense signal intensity on T1-weighted images and hypointense signal intensity on T2-weighted/fat-suppressed T2-weighted images.</div></div><div><h3>CONCLUSION</h3><div>CT and MRI offer respective advantages in the diagnosis of IOWFB. CT is the preferred modality for patients with suspected IOWFB, while MRI provides valuable supplementary information.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"84 ","pages":"Article 106859"},"PeriodicalIF":2.1,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Sigmoid take-off” to define recto-sigmoid junction and its impact on rectal cancer classification, staging, and management","authors":"A. Augustine ,&nbsp;G.H. Cecil ,&nbsp;A. Lakhani ,&nbsp;H.V. Kanamathareddy ,&nbsp;R. John ,&nbsp;B. Simon ,&nbsp;A. Eapen ,&nbsp;R. Mittal ,&nbsp;A. Chandramohan","doi":"10.1016/j.crad.2025.106858","DOIUrl":"10.1016/j.crad.2025.106858","url":null,"abstract":"<div><h3>Aim</h3><div>The primary objective of this study was to determine the clinical impact of using sigmoid take-off (STO) in the management of rectal cancer. We also evaluated the inter-observer reliability in the identification of STO.</div></div><div><h3>Material and Methods</h3><div>This retrospective study reviewed staging MRI of patients with mid and high-rectal cancers performed between January 2019 and December 2022. The location of the tumour was reclassified based on STO as defined by D'Souza <em>et al.</em> (2018) and compared with the location determined based on distance from the anal verge. The proportions of cases that show a change in tumour location from rectal cancer to sigmoid cancer and the potential change in treatment were noted. The interobserver agreement for the location of STO and the location of tumours from STO was studied among four subspecialised abdominal radiologists.</div></div><div><h3>Results</h3><div>Out of 134 rectal cancer patients included, STO-based assessment resulted in the reclassification of 13.4% (n=18) cases into sigmoid cancer. There was, however, no change in the stage of cancer. Among these 18 patients, there would have been a change in management in 5 patients had the initial assessment been a sigmoid cancer. There was excellent agreement among the radiologists for measuring the distance of STO from the anal verge (ICC = 0.883, p&lt;0.001) and determining the location of the tumour based on STO (K = 0.82, p&lt;0.001).</div></div><div><h3>Conclusions</h3><div>Using STO changed the location of tumours in 13.4% of high- and mid-rectal cancers. There was excellent agreement among radiologists regarding determining STO and identifying tumour locations using STO.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"84 ","pages":"Article 106858"},"PeriodicalIF":2.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiomics analysis based on 18F-fluorodeoxyglucose positron emission tomography/computed tomography for differentiating the histological classification of peripheral neuroblastic tumours","authors":"L. Feng ,&nbsp;X. Yao ,&nbsp;C. Wang ,&nbsp;H. Zhang ,&nbsp;W. Wang ,&nbsp;J. Yang","doi":"10.1016/j.crad.2025.106851","DOIUrl":"10.1016/j.crad.2025.106851","url":null,"abstract":"<div><h3>Aim</h3><div>To create a radiomics nomogram based on ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography and assess the efficacy of this nomogram in differentiating ganglioneuroblastoma from neuroblastoma in peripheral neuroblastic tumours (PNTs).</div></div><div><h3>Materials and Methods</h3><div>One hundred and ninety-nine patients with PNTs were retrospectively included, including 115 neuroblastoma patients and 84 ganglioneuroblastoma patients, who were randomly split into the training and test sets according to a ratio of 7:3. The 3D slicer was used to delineate the primary tumour, then radiomics features were extracted and selected, and a radiomics model was built using the optimal radiomics features. The clinical model was constructed from independent clinical risk factors. A radiomics nomogram was developed by multivariate logistic regression analysis incorporating independent clinical risk factors and radiomics features. Model performance was assessed using receiver operating characteristic curves and decision curve analysis.</div></div><div><h3>Results</h3><div>The radiomics model based on the selection of 14 radiomics features was developed. The clinical model was constructed by combining age at diagnosis and 1p aberrations. The radiomics nomogram demonstrated the optimal diagnostic value in distinguishing between ganglioneuroblastoma and neuroblastoma, with an area under the receiver operating characteristic curve of 0.857 and 0.795 in the training and test sets, respectively. The decision curve analysis and calibration curves also showed good performance for the nomogram.</div></div><div><h3>Conclusions</h3><div>The radiomics nomogram could improve diagnostic performance by differentiating the histological classification of PNTs.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"84 ","pages":"Article 106851"},"PeriodicalIF":2.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Utility of zero echo time (ZTE) sequence for assessing bony lesions of skull base and calvarium: Challenges and expanding the applications of ZTE MRI in paediatric radiology","authors":"T.S.E. Tan","doi":"10.1016/j.crad.2025.106855","DOIUrl":"10.1016/j.crad.2025.106855","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"84 ","pages":"Article 106855"},"PeriodicalIF":2.1,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143578167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}