T. Pan , X. Tian , Y. Liu , H.-Q. Yang , G.-J. Ma , X.-N. Han , C.-Y. Li
{"title":"Corrigendum to “The role of the right atrial appendage and right atrium in post-radiofrequency ablation recurrence in different types of atrial fibrillation [Clin Radiol 79 (11) (2024) e1312–e1320]”","authors":"T. Pan , X. Tian , Y. Liu , H.-Q. Yang , G.-J. Ma , X.-N. Han , C.-Y. Li","doi":"10.1016/j.crad.2025.106945","DOIUrl":"10.1016/j.crad.2025.106945","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"86 ","pages":"Article 106945"},"PeriodicalIF":2.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
X. Wang , X. Tian , Y. Peng , D. Zhang , Y. Wang , L. Zhang
{"title":"T1 mapping of the sagittal images of the cervical cord: a potential biomarker to predict the severity of cervical spondylotic myelopathy","authors":"X. Wang , X. Tian , Y. Peng , D. Zhang , Y. Wang , L. Zhang","doi":"10.1016/j.crad.2025.106974","DOIUrl":"10.1016/j.crad.2025.106974","url":null,"abstract":"<div><h3>Aims</h3><div>To investigate the applied value of quantitative assessment of the cervical spondylotic myelopathy (CSM) severity using T1 mapping of cervical spinal cord.</div></div><div><h3>Materials and Methods</h3><div>A total of 133 patients with CSM (CSM group) and 30 healthy volunteers (control group) were prospectively recruited between September 2023 and March 2024. Patients with CSM were categorized into a mild group (mJOA ≥12) and a severe group (mJOA <12) according to the modified Japanese Orthopedic Association scores (mJOA). Cervical axial and sagittal T2WI, as well as sagittal T1 mapping were performed on all subjects. In the control group, native T1 was measured at each disc level (C2–C7); in the CSM group, native T1 was measured at the stenotic location, the disc level above and below the stenotic location (T1<sub>stenosis</sub>,T1<sub>above</sub> and T1<sub>below</sub>). Interobserver agreement, univariate analyses, pearson's correlations, and ROC curves were performed.</div></div><div><h3>Results</h3><div>Native T1 showed excellent interobserver agreement in the control group. The mean T1 value of the control group (772.94 ± 57.87 ms) was significantly lower than the T1<sub>stenosis</sub>(908.89 ± 135.61ms),T1<sub>above</sub> (844.66 ± 126.97ms) and T1 <sub>below</sub> (855.99 ± 125.52ms).The distribution of mJOA, T2(+), T1 <sub>stenosis</sub>, T1<sub>above</sub> and T1<sub>below</sub> between the mild and severe groups differed (P<0.05). All native T1 of CSM group showed negative correlations with mJOA. AUCs of T1 <sub>stenosis</sub>,T1<sub>above</sub> and T1<sub>below</sub> identified the severity of CSM patients as 0.857, 0.711, and 0.733, respectively.</div></div><div><h3>Conclusions</h3><div>T1 mapping can quantitatively assess the severity of CSM patients, and native T1 of spinal cord at the stenosis level is a valuable parameter to differentiate between patients with mild and severe CSM.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106974"},"PeriodicalIF":2.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on “Exploring the correlation between high-risk coronary plaque and hepatic fat fraction in non-alcoholic fatty liver disease using spectral CT”","authors":"R. Sah MD , A. Mathur MDS","doi":"10.1016/j.crad.2025.106970","DOIUrl":"10.1016/j.crad.2025.106970","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106970"},"PeriodicalIF":2.1,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144297916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on “combining conventional MRI parameters with clinicopathologic data for differentiation of the three-tiered HER2 status in breast cancer”","authors":"R. Mehta, R. Sah","doi":"10.1016/j.crad.2025.106971","DOIUrl":"10.1016/j.crad.2025.106971","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106971"},"PeriodicalIF":2.1,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144297917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Rehman, C McCarthy, M Chetan, Y-L Li, M Gillies, T Cosker, F Wu, P C Lyon
{"title":"Imaging and intervention for soft tissue tumours in the era of locoregional therapies and immunotherapy.","authors":"S Rehman, C McCarthy, M Chetan, Y-L Li, M Gillies, T Cosker, F Wu, P C Lyon","doi":"10.1016/j.crad.2025.106969","DOIUrl":"https://doi.org/10.1016/j.crad.2025.106969","url":null,"abstract":"<p><p>As part of a multidisciplinary team, clinical radiology plays key roles in the diagnosis, staging and treatment response assessment for soft tissue sarcoma (STS) and desmoid tumours (DTs), typically using a combination of ultrasound and magnetic resonance imaging (MRI) modalities. There is an increasing role for interventional radiology in the treatment of recurrent and oligometastatic disease in these tumour types. This clinical radiology review is aimed primarily at non-specialist cross-sectional consultant radiologists and more junior radiology consultants/specialist trainees with a special interest in musculoskeletal oncology. The existing role of F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and MRI for assessment of treatment response in STS and DT, including the emerging role of whole-body MRI is outlined. Response metrics including Response Evaluation Criteria in Solid Tumors 1.1 (RECIST 1.1), modified RECIST, Positron Emission Tomography Response Criteria in Solid Tumours (PERCIST), immune Response Evaluation Criteria in Solid Tumors, iPERCIST and non-perfused volume ratio are also discussed in context. We introduce the potential role for locoregional therapies (LRTs), including microwave, cryotherapy and therapeutic ultrasound-based treatments as adjunctive treatments for selected cases within the current UK guidelines. We discuss the potential of high intensity focused ultrasound and other LRTs to release sarcoma tumour antigens systemically with the potential to enhance anti-tumour immunity (the 'abscopal' effect). With increasing indications and availability of locoregional therapies (LRTs) and the first indications of immunotherapy for selected subtypes of STS, potential future directions in functional imaging capability for STS and DT are also discussed.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":" ","pages":"106969"},"PeriodicalIF":2.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to Editor regarding, “Clinical effect of catheter-directed thrombolysis combined with intermittent pneumatic compression on lower extremity deep venous thrombosis”","authors":"G. Gambhir","doi":"10.1016/j.crad.2025.106972","DOIUrl":"10.1016/j.crad.2025.106972","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106972"},"PeriodicalIF":2.1,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144297915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Ziada, M. Siu, R. Gatt, N. Jallad, N. Hartley, G. McDonald, M. Al-Attar
{"title":"High-risk breast cancer screening with MRI: diagnostic performance of a local scoring system","authors":"K. Ziada, M. Siu, R. Gatt, N. Jallad, N. Hartley, G. McDonald, M. Al-Attar","doi":"10.1016/j.crad.2025.106968","DOIUrl":"10.1016/j.crad.2025.106968","url":null,"abstract":"<div><h3>Aim</h3><div>Breast MRI is widely used for screening high-risk women, though its high cost and false positive rates pose challenges. There is growing research exploring the potential integration of breast MRI into the screening of other patient groups, including women with dense breasts and/or an intermediate lifetime risk for breast cancer. We evaluated the diagnostic performance of Leicester scoring system (LSS) in managing lesions detected at high-risk screening breast MRI.</div></div><div><h3>Materials and Methods</h3><div>In this retrospective study, 73 lesions from 174 high-risk breast MRI studies over a 10-year period (2014–2024) were analyzed. Included lesions were masses, foci, and linear/ductal non–mass-like enhancement. Lesions were classified and scored using the LSS, which combines five MRI descriptors: margins, signal patterns, internal enhancement, contrast kinetics, and DWI patterns.</div></div><div><h3>Results</h3><div>All 10 malignant lesions had LSS scores ≥2 (mean: 4.6). Of the 40 benign lesions (excluding IMLNs), 87.5% had scores <2 (mean: 1.1). The optimal cut-off of 2 achieved 100% sensitivity and 87.5% specificity (<em>p</em><0.001). Typical IMLNs, which often mimic malignancy on imaging, should be excluded from scoring and considered benign when they are not significant by size criteria. Using LSS could potentially avoid biopsy in 48% of lesions, or up to 79% if IMLNs are excluded, without missing any cancers. The inter-reader agreement was very good, with a K-value of 0.81 (<em>p</em><0.001).</div></div><div><h3>Conclusion</h3><div>Leicester Scoring System has the potential to avoid up to 79% of unnecessary biopsies without compromising cancer detection. Our results challenge the assumption that cancers may present with exclusively benign features in this cohort of women.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106968"},"PeriodicalIF":2.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144307136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Riley , S. Elgarwany , P. Arundel , N.J. Bishop , A.C. Offiah
{"title":"An observational study of the prevalence of classic metaphyseal fractures in children with osteogenesis imperfecta in the first two years of life","authors":"E. Riley , S. Elgarwany , P. Arundel , N.J. Bishop , A.C. Offiah","doi":"10.1016/j.crad.2025.106964","DOIUrl":"10.1016/j.crad.2025.106964","url":null,"abstract":"<div><h3>AIM</h3><div>Classic metaphyseal fractures are highly suggestive of inflicted injury. Osteogenesis imperfecta (OI) is an important differential in infants presenting with unexplained fracture(s), and some argue that classic metaphyseal fractures occur accidentally in children with OI. This study sought to assess the prevalence of classic metaphyseal fractures in children with OI during the first 2 years of life.</div></div><div><h3>MATERIALS AND METHODS</h3><div>This was a retrospective observational cohort study of children with OI less than 2 years of age between 01/01/2010 and 31/12/2021. Radiographs and reports were reviewed by two observers. The site and type of fractures were recorded along with other radiological features of OI. Descriptive and inferential statistics were used to analyse the results.</div></div><div><h3>RESULTS</h3><div>There were 109 eligible patients (53 female) who had a total of 3,142 images (1,949 images in those less than 1 year old). There were 87 patients (79.8%) with a total of 462 long bone fractures, of which 386 (83.5%) were diaphyseal and 76 (16.5%) were at the junction of the diaphysis and metaphysis. No classic metaphyseal fractures were identified.</div></div><div><h3>CONCLUSION</h3><div>The absence of classic metaphyseal fractures in this large cohort suggests that OI is rarely, or not at all, associated with such fractures. However, metadiaphyseal fractures, reflecting bone fragility, are common; distinction should be made between ‘classic metaphyseal’ and ‘metadiaphyseal’ fractures to facilitate clinical decision-making. The unspecified term ‘metaphyseal fracture’ should be avoided. Children less than 2 years old with OI and classic metaphyseal fractures should be thoroughly investigated to exclude inflicted injury.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106964"},"PeriodicalIF":2.1,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144253815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
X. Sun , W. Xu , X. Liu , J. Long , P. Dou , H. Zhang , A. Sun , S. Zhang , K. Xu , Y. Meng
{"title":"Comparison of perfusion defects parameters in dual-energy computed tomography (CT) pulmonary angiography across arterial phase and venous phase","authors":"X. Sun , W. Xu , X. Liu , J. Long , P. Dou , H. Zhang , A. Sun , S. Zhang , K. Xu , Y. Meng","doi":"10.1016/j.crad.2025.106963","DOIUrl":"10.1016/j.crad.2025.106963","url":null,"abstract":"<div><h3>AIM</h3><div>This study aims to compare dual-energy computed tomography pulmonary angiography (DE-CTPA) perfusion defects (PD) parameters between the arterial (AP) and venous phases (VP).</div></div><div><h3>MATERIALS AND METHODS</h3><div>This retrospective study analysed the database of patients who underwent dual-phase DE-CTPA examinations. The patients were categorised into three groups based on their Qanadli (Q) scores (Group A: Q = 0%, Group B: 0% < Q < 50%, and Group C: Q ≥ 50%). PD parameters, including perfusion defect volume (PDV) and its percentage relative to total lung volume (<sub>Rel</sub>PDV), were derived from the dual-phase DE-CTPA images. Differences in PD parameters were assessed between phases and among the three groups.</div></div><div><h3>Results</h3><div>A total of 81 consecutive patients were included in the study (44 females [54.3%]; mean age: 68.37 ± 13.01 years). <sub>Rel</sub>PDV was significantly higher in the AP compared to the VP (P0.030). Phase comparisons within each group showed no statistically significant differences in PDV between the AP and VP for Group C. However, in Groups A and B, both PDV and <sub>Rel</sub>PDV were higher in the AP than in the VP (all P<0.05). When comparing the three groups, there were no statistically significant differences in PDV or <sub>Rel</sub>PDV for AP. In VP, PDV, and <sub>Rel</sub>PDV increased with higher Q scores, with Group C showing statistically significant differences compared to Groups A and B.</div></div><div><h3>Conclusion</h3><div>The PD parameters of DE-CTPA differed between AP and VP. This study highlights the limitations of relying on iodine maps in AP to estimate lung perfusion.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"87 ","pages":"Article 106963"},"PeriodicalIF":2.1,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144253742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}