D. Gilland, B. Welch, Seung Joon Lee, B. Kross, A. Weisenberger
{"title":"A prototype gamma tomosynthesis system for molecular breast imaging","authors":"D. Gilland, B. Welch, Seung Joon Lee, B. Kross, A. Weisenberger","doi":"10.1109/NSSMIC.2015.7582258","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582258","url":null,"abstract":"We are developing an improved gamma camera for molecular breast imaging (MBI) that allows tomographic imaging and improved signal-to-noise over conventional planar methods. We have built a novel gamma camera for MBI that utilizes limited angle tomography, similar to x-ray tomosynthesis, to generate images with depth information and improved signal-to-noise. A unique feature of the gamma tomosynthesis system is a variable-angle slant hole (VASH) collimator. This collimator allows the camera to remain flush against the compression paddle during the tomographic acquisition, which achieves high spatial resolution and simplified detector motion. We constructed a VASH collimator from a stack of tungsten sheets, each sheet containing a matrix of holes created by photo-etching. With the holes of the sheets aligned, a parallel-hole collimator is created; shearing the sheets creates a variable angle slant hole collimator. The shearing is controlled by a motorized mechanism. The collimator was mounted on a commercial MBI camera and projection data were acquired of a set of capillary tube line sources over a 50° range of angles. The projection data were reconstructed using the iterative MLEM method. Results demonstrated the ability of the system to resolve in the depth dimension, and spatial resolution matched expected values. We conclude that the proposed gamma tomosynthesis system has the potential to provide improved signal-to-noise over conventional MBI methods and allow a reduction in the administered radioactivity and patient dose.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117016489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of a digital unrestrained mouse phantom with non-periodic deformable motion","authors":"I. Klyuzhin, G. Stortz, V. Sossi","doi":"10.1109/NSSMIC.2015.7582140","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582140","url":null,"abstract":"We describe a method to generate a digital phantom of an unrestrained rodent that incorporates non-periodic motion with deformation. The phantom is represented by a deformable point cloud with time-dependent point coordinates, activity and attenuation. Motion is simulated by applying time-varying mesh deformation operators to the point cloud. To compare the simulated motion to the motion of a live rodent, the behavior of an unrestrained mouse was recorded using a depth camera, and the kinematic parameters of motion were measured. To generate simulated coincidence data, the phantom is voxelized and used in the Monte-Carlo emission simulation. The combined emission and motion data can be used for the development and validation of the image reconstruction algorithms with deformable motion correction.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117018658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Grodzicka, T. Szczesniak, M. Moszynski, L. Swiderski, M. Szawłowski
{"title":"Silicon photomultipliers in scintillation detectors used for gamma-ray energies up to 6.1 MeV","authors":"M. Grodzicka, T. Szczesniak, M. Moszynski, L. Swiderski, M. Szawłowski","doi":"10.1109/NSSMIC.2015.7581742","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581742","url":null,"abstract":"The aim of this paper is to study usefulness of SiPM light readout in detection of gamma rays up to 6.1MeV in combination with various scintillators. The reported measurements were made with 3 samples of one type of Hamamatsu TSV (Through Silicon Via technology) MPPC arrays. These 4×4 channel arrays have a 50×50 μm2 cell size and 12×12 mm2 effective active area. All the tests were done in a climatic chamber. The following scintillators were used: CsI(Tl), CeBr3, NaI(Tl). The studies are focused on optimization of the MPPC performance for practical use in detection of high energy gamma rays. The optimization includes selection of the optimum operating voltage in respect to the energy resolution, verification of the dynamic range, linearity and pulse amplitude. The energy spectra for energies between 320keV and 6.1MeV are presented and compared with data acquired with a classic photomultiplier. Such comparison allowed study of nonlinearity of the tested MPPCs, correction of the energy spectra and proper analysis of the energy resolution. The temperature tests show strong breakdown voltage dependence on the temperature change and define requirements for the stabilization method in real life applications.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117077944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wavelet analysis of high and low resolution gamma-ray spectra: An investigation of peak finding techniques","authors":"C. I. Thompson, K. Vaughan, R. Turner","doi":"10.1109/NSSMIC.2015.7582000","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582000","url":null,"abstract":"For the detection of radiological materials, peak identification within gamma spectroscopy data is a useful tool. This paper discusses the application of wavelet analysis as a peak finding technique to high resolution data recorded by high purity germanium (HPGe) detectors. Whilst the wavelet method has been previously applied to high efficiency/low resolution data, this work considers the applicability of wavelet analysis to high resolution spectral datasets with varying levels of background. An algorithm has been developed that automatically locates wavelet transform modulus maxima (WTMM) lines; the method identifies local maxima and minima of the scalogram joining data points within the same potential. The approach was applied to analyse a range of experimental recorded radiation spectra, both from shielded and un-shielded sources. Peak locations were found by comparing peak widths with those expected based on the detector resolution function (DRF), alongside WTMM straightness and line length filter tests. Findings indicated that, when implemented in this approach, the wavelet analysis method was applicable to the identification of high-resolution photopeaks when concealed within varying levels of background.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128377065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Aleotti, Giorgio Micconi, S. Caselli, G. Benassi, N. Zambelli, D. Calestani, M. Zanichelli, M. Bettelli, A. Zappettini
{"title":"Unmanned aerial vehicle equipped with spectroscopic CdZnTe detector for detection and identification of radiological and nuclear material","authors":"J. Aleotti, Giorgio Micconi, S. Caselli, G. Benassi, N. Zambelli, D. Calestani, M. Zanichelli, M. Bettelli, A. Zappettini","doi":"10.1109/NSSMIC.2015.7582264","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582264","url":null,"abstract":"Localization and identification of nuclear and radiological material are main issues in case of nuclear accident or terrorist attack. In these cases, the use of a unmanned aerial vehicle would be highly recommended in order to preserve the safety of the human operators. For this purpose, we have integrated a compact, light, low power operating, CZT-based gamma ray detector on a commercially available UAV. The system allows exploration of potentially dangerous areas without a close exposure of the human operator. The operator is able to provide motion commands to the UAV while receiving force feedback from a 3DOF haptic interface. Force feedback provides an attractive basin around the location of the most intense detected radiation. A field experiment has been carried out and a 192Ir nuclear source has been localized and identified exploiting the novel teleoperation system.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128641185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Moscatelli, P. Maccagnani, D. Passeri, G. Bilei, L. Servoli, A. Morozzi, G. Betta, R. Mendicino, M. Boscardin, N. Zorzi
{"title":"Measurements and TCAD simulations of bulk and surface radiation damage effects in silicon detectors","authors":"F. Moscatelli, P. Maccagnani, D. Passeri, G. Bilei, L. Servoli, A. Morozzi, G. Betta, R. Mendicino, M. Boscardin, N. Zorzi","doi":"10.1109/NSSMIC.2015.7581944","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581944","url":null,"abstract":"In this work we propose the application of a radiation damage model based on the introduction of deep level traps/recombination centers suitable for device level numerical simulation of radiation detectors at very high fluences (e.g. 1÷2×1016 1-MeV equivalent neutrons per square centimeter) combined with a surface damage model developed by using experimental parameters extracted from measurements from gamma irradiated p-type dedicated test structures.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129153072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Pacher, E. Monteil, A. Rivetti, N. Demaria, M. D. Da Rocha Rolo
{"title":"A low-power low-noise synchronous pixel front-end chain in 65 nm CMOS technology with local fast ToT encoding and autozeroing for extreme rate and radiation at HL-LHC","authors":"L. Pacher, E. Monteil, A. Rivetti, N. Demaria, M. D. Da Rocha Rolo","doi":"10.1109/NSSMIC.2015.7581969","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581969","url":null,"abstract":"A low-power and low-noise synchronous front-end chain in a commercial 65 nm CMOS technology suitable for the future pixel upgrades at the CERN Large Hadron Collider (LHC) is presented. A shaper-less Charge-Sensitive Amplifier (CSA) with constant current feedback provides triangular pulse shaping for linear Time-over-Threshold (ToT) charge measurement. The sensor leakage current is compensated by the same feedback network. A track-and-latch voltage comparator is adopted for the hit discrimination. The hit generation is synchronized with a 40 MHz clock, minimizing time-walk issues in the time-stamp assignment. Fast ToT charge encoding up to 8-bit resolution can be retrieved at the pixel level exploiting a high-frequency self-generated clock signal. This is obtained by turning the latch into a voltage-controlled oscillator (VCO) using asynchronous logic. Pixel-to-pixel threshold variations are compensated by means of an autozeroed scheme, thus avoiding the need of a on-pixel D/A converter. An array of 8 × 8 cells with 50 μm × 50 μm pixel size has been prototyped. Design specifications, implementation and test results are discussed.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129309995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Formation of diode detectors by nanosecond laser irradiation of CdTe-In interface from the semiconductor side","authors":"K. Zelenska, D. Gnatyuk, T. Aoki","doi":"10.1109/NSSMIC.2015.7582277","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582277","url":null,"abstract":"We suggest the principally improved technique of the laser-induced doping by irradiation of the In/CdTe structures from the CdTe side with YAG:Nd laser pulses (λ = 1064 nm, τ = 8 ns). The computer simulation of laser heating and temperature calculations were used to choose the optimal regimes for achieving the effective In doping of thin and thicker CdTe layers near the CdTe-In interface under laser irradiation through the CdTe bulk. The formed M-p-n In/CdTe/Au diodes were tested by electrical and spectral measurements. The diode detectors showed sharp rectification with low leakage current and good energy resolution.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"209 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124706155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenyuan Qi, T. Xia, Xiaofeng Niu, Changguo Ji, Mark Winkler, E. Asma, Wenli Wang
{"title":"A non-local means post-filter with spatially adaptive filtering strength for whole-body PET","authors":"Wenyuan Qi, T. Xia, Xiaofeng Niu, Changguo Ji, Mark Winkler, E. Asma, Wenli Wang","doi":"10.1109/NSSMIC.2015.7582060","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582060","url":null,"abstract":"We propose a spatially adaptive Non-Local Means (NLM) post-filtering approach for whole-body clinical Positron Emission Tomography (PET) imaging. Our approach is aimed at avoiding different effective smoothing strengths in different organs that result from with traditional non-adaptive NLM. We vary the smoothing strength according to the intensity level around a given voxel such that regions with low absolute noise levels are smoothed less and those with high absolute noise levels are smoothed more. We evaluated this approach and compared it to alternative filtering techniques by inserting lesions of known size and activity into clinical datasets acquired on a Toshiba CelesteionTM TOF-PET/CT scanner. Images were reconstructed with list-mode Ordered-Subset Expectation-Maximization (OSEM) algorithm with all physical corrections inside the system model prior to post-filtering. We qualitatively evaluated the techniques by comparing the differences between filtered and original images and quantitatively evaluated them using lesion contrast vs. background variability curves. Both evaluations showed that the proposed method could better accommodate varying noise statistics in whole-body PET images and better preserve lesion contrast across different anatomical regions.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129661177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"8-Channels high-resolution TDC in FPGA","authors":"N. Lusardi, A. Geraci","doi":"10.1109/NSSMIC.2015.7581245","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581245","url":null,"abstract":"In this contribution we presented the implementation of a tapped-delay-line (TDL) TDC with 8-channels in a Xilinx Kintex-7 FPGA device with r.m.s. value of the resolution around 20 ps. Main features of the instrument are the resource-saving and low-power architecture, the presence of an edge detector able to sense the position of the transition propagating along the delay line within one clock cycle, the interface through a USB 3.0 communication gate.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126812172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}