2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)最新文献_第6页

Simulation for CaLIPSO PET scanner CaLIPSO PET扫描仪的仿真

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582246

O. Kochebina, S. Jan, Viatcheslav Sharyy, X. Mancardi, P. Verrecchia, E. Ramos, D. Yvon

引用次数: 2

An analytical method for quantitative reconstruction of X-ray fluorescence computed tomography with attenuation correction 衰减校正的x射线荧光计算机断层成像定量重建分析方法

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582032

Wei Feng, Zheng Li, Dong Han, Tianyi Yangdai

引用次数: 0

Highly multiplexed DOI PET detector based on SiPM sensors 基于SiPM传感器的高复用DOI PET检测器

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582150

R. Chil, G. Konstantinou, M. Desco, J. Vaquero

引用次数: 0

Multi-pixel photon counter module for MRI compatible application 用于MRI兼容应用的多像素光子计数器模块

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582021

K. Shimizu, K. Hakamata, T. Sakai, H. Yamauchi, H. Uchida, M. Hirayanagi, S. Nakamura, F. Nishikido, E. Yoshida, M. Suga, T. Obata, T. Yamaya

{"title":"Multi-pixel photon counter module for MRI compatible application","authors":"K. Shimizu, K. Hakamata, T. Sakai, H. Yamauchi, H. Uchida, M. Hirayanagi, S. Nakamura, F. Nishikido, E. Yoshida, M. Suga, T. Obata, T. Yamaya","doi":"10.1109/NSSMIC.2015.7582021","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582021","url":null,"abstract":"A new detector for PET using multi-pixel photon counters (MPPCs) was developed for MRI compatible applications. This module has an 8 × 8 MPPC array, each segment has a 3 mm × 3 mm active area, and the pitch of the array is 4.1 mm in both directions. A temperature sensor is attached to the back of the array for temperature compensation. The MPPC array is connected to the front-end circuit with a detachable flexible printed circuit cable (FPC), which provides flexibility for detector arrangement. The front-end circuit consists of preamplifiers, a register network, buffer amplifiers, a built-in high voltage (HV) unit, and an embedded microprocessor unit. The HV unit is a down-regulator and requires an external HV supply. The preamplifier also has a sum output, which can be used for timing pick-off and energy discrimination. With LYSOs, the timing performance was evaluated using flexible printed cables of two different lengths. Set in a copper shield box, energy spectra and flood images were evaluated with a 3T-MRI Very little interference was observed during simultaneous MRI measurements.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121392350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Impact of time-of-flight image reconstruction in PET parametric imaging 飞行时间图像重构对PET参数成像的影响

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582177

F. Kotasidis, A. Mehranian, H. Zaidi

{"title":"Impact of time-of-flight image reconstruction in PET parametric imaging","authors":"F. Kotasidis, A. Mehranian, H. Zaidi","doi":"10.1109/NSSMIC.2015.7582177","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582177","url":null,"abstract":"Kinetic parameter estimation in dynamic PET imaging requires reconstruction of multiple time frames. Due to the limited counting statistics and reduced signal-to-noise ratio (SNR) in each frame, parametric maps suffer from reduced accuracy and precision. Therefore image reconstruction strategies improving upon the SNR are particularly important in the context of parametric imaging. Time of flight image reconstruction has been shown to improve the SNR and increase the effective sensitivity. However so far the benefit of TOF has only been demonstrated in static imaging applications with potentially substantial benefits when used in dynamic pharmacokinetic imaging applications. Using traditional dynamic 3D as well as direct 4D image reconstruction algorithms we evaluate the benefit of TOF on kinetic parameter estimation using various TOF resolutions, kinetic models and count levels. Initial data suggest that both bias and variance in the kinetic parameters are reduced, with improvements depending on the kinetic model and becoming more significant at increased TOF resolutions. Incorporating TOF within direct 4D image reconstruction and combining the respecting SNR gains results in substantial improvements in parametric maps compared to traditional post reconstruction kinetic analysis.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"581 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116339940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection and characterization of shielded highly enriched uranium under active interrogation through time correlated fission events 利用时间相关裂变事件在主动讯问下探测和表征屏蔽高浓缩铀

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7581767

M. Monterial, P. Marleau, S. Pozzi

{"title":"Detection and characterization of shielded highly enriched uranium under active interrogation through time correlated fission events","authors":"M. Monterial, P. Marleau, S. Pozzi","doi":"10.1109/NSSMIC.2015.7581767","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581767","url":null,"abstract":"The time-correlated pulse-height (TCPH) distribution can be used to differentiate between multiplying (e.g 235U, 239Pu) and non-multiplying (e.g Am-Li, 252Cf) sources. In the past, this approach proved effective at characterizing the multiplication of alpha phase plutonium metal through a passive measurement. Recently, Sandia National Laboratories has completed a measurement campaign with its new Correlated Radiation Signature (CoRS) system involving active interrogation of highly enriched uranium (HEU) with an Am-Li source. An additional obstacle was introduced to the measurement configuration by shielding the HEU with depleted uranium (DU). Simulation results have proven Am-Li source to be a suitable interrogating source because of its relatively low-energy neutron spectrum. The TCPH distribution was successfully used to determine the presence of a multiplying medium inside DU shells. The correlation between multiplication and an empirical parameters broke down for externally driven configurations, but in all cases the presence of a multiplying source was detected.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126267455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of optimized prompt gamma detection strategy for real-time Bragg Peak tracking in proton radiation therapy 质子放射治疗中实时Bragg峰跟踪的优化提示伽马探测策略研究

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582237

M. Zarifi, Y. Qi, S. Guatelli, Brian Hutton, Amir Rosenfeld

{"title":"Investigation of optimized prompt gamma detection strategy for real-time Bragg Peak tracking in proton radiation therapy","authors":"M. Zarifi, Y. Qi, S. Guatelli, Brian Hutton, Amir Rosenfeld","doi":"10.1109/NSSMIC.2015.7582237","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582237","url":null,"abstract":"Prompt gamma (PG) ray signal from proton radiation has been proposed for in vivo beam range verification to provide unique real-time tracking of the Bragg Peak (BP) during proton therapy (PT) delivery. In this study, we investigate possible strategies to optimize PG detection for BP tracking in proton radiation therapy. Extensive Geant4 Monte Carlo (MC) simulations have been used to study the energy spectral, spatial and timing characteristics of PG emission signal from 200 MeV proton pencil beam irradiations with water and PMMA phantoms. These include their relationship with the position of the BP and the background of the neutron field originated by the proton beams. Then the optimal energy window, angular window and timing window for PG imaging detection can be determined. Our results show that there could exist an optimal energy window for PG detection around 4.44 MeV. PG emissions show a backward angular preference while neutron emissions have a forward angular preference. Furthermore, employing a timing window could further improve the PG signal detection from strong background interferences of neutrons. Both energy and time resolved PG detection is a promising solution. These results indicate that there could exist an optimized strategy for PG signal detection. Utilizing appropriate energy window, angular window and timing window, PG image formation could be significantly improved for BP tracking.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126228443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Advancements in microstructured semiconductor neutron detector (MSND)-based instruments 微结构半导体中子探测器(MSND)仪器的研究进展

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7581971

R. Fronk, S. Bellinger, L. C. Henson, D. Huddleston, T. Ochs, M. Reichenberger, C. J. Rietcheck, Colten T. Smith, T. Sobering, J. Shultis, D. Mcgregor

{"title":"Advancements in microstructured semiconductor neutron detector (MSND)-based instruments","authors":"R. Fronk, S. Bellinger, L. C. Henson, D. Huddleston, T. Ochs, M. Reichenberger, C. J. Rietcheck, Colten T. Smith, T. Sobering, J. Shultis, D. Mcgregor","doi":"10.1109/NSSMIC.2015.7581971","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581971","url":null,"abstract":"Microstructured semiconductor neutron detectors (MSNDs) represent a compact, low-cost, high-efficiency means of solid-state thermal neutron detection. Trenches are etched into a 1-cm2 or 4-cm2 active area pn-junction diode and backfilled with 6LiF neutron converting material. Charged-particle reaction products produced from neutron capture within the conversion material can be measured to indicate the presence of neutrons. MSNDs can be arranged into larger instruments due to their small size, high-efficiency, and low power consumption. A small, inexpensive electronics package named the `Domino' was developed to facilitate the deployment of the MSND™ technology. The Domino is a complete electronics package that supports a single MSND™ with all necessary signal processing electronics. The Domino electronics were tiled together to form large-area arrays and portable detector arrays. Both were characterized with a small 252Cf source. A hand-held portable `Briefcase' detector with 84 Dominoes™, forming a 30 cm × 38 cm array, weighed 21 lbs. A vehicle-portable `Panel Array' detector with 480 Dominoes formed a 1 m × 1 m. For a bare 252Cf source, the `Briefcase' detector and the `Panel Array' detector yielded 0.27 ± 0.01 cps ng-1 (at 2 m) and 0.45 ± 0.01 cps ng-1 (at 5 m), respectively. Modified Domino packages (with upgraded MSNDs) were arranged into a 2-in. diameter, 6-in. long cylindrical form factor (HeRep Mk II) for direct 3He replacement, matching the efficiency of a 4-atm 3He with similar dimensions. A third generation helium replacement (HeRep Mk III) was constructed to replace more compact 3He form factors, with a 0.75-in. diameter and 4.5-in. length. Populated with dual-sided MSNDs, this detector yielded 0.293 ± 0.003 cps ng-1 for bare 252Cf at 0.2 m.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121620114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Blind analysis of CT image noise using residual denoised images 基于残差去噪的CT图像噪声盲分析

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7582055

Sohini Roychowdhury, Nathan Hollraft, A. Alessio

{"title":"Blind analysis of CT image noise using residual denoised images","authors":"Sohini Roychowdhury, Nathan Hollraft, A. Alessio","doi":"10.1109/NSSMIC.2015.7582055","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582055","url":null,"abstract":"CT protocol design and quality control would benefit from automated tools to estimate the quality of generated CT images. These tools could be used to identify erroneous CT acquisitions or refine protocols to achieve certain signal to noise characteristics. This paper investigates blind estimation methods to determine global signal strength and noise levels in chest CT images. Methods: We propose novel performance metrics corresponding to the accuracy of noise and signal estimation. We implement and evaluate the noise estimation performance of six spatial- and frequency-based methods, derived from conventional image filtering algorithms. Algorithms were tested on patient data sets from whole-body repeat CT acquisitions performed with a higher and lower dose technique over the same scan region. Results: The proposed performance metrics can evaluate the relative tradeoff of filter parameters and noise estimation performance. The proposed automated methods tend to underestimate CT image noise at low-flux levels. Initial application of methodology suggests that anisotropic diffusion and Wavelet-transform based filters provide optimal estimates of noise. Furthermore, methodology does not provide accurate estimates of absolute noise levels, but can provide estimates of relative change and/or trends in noise levels.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134414091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Probing the qualities of diamond detectors for neutron identification at radiotherapy facilities 放射治疗设施中子识别用金刚石探测器质量的探讨

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2015-10-01 DOI: 10.1109/NSSMIC.2015.7581916

F. Manchado, L. Acosta, I. Martel, J. Sánchez, J. Dueñas, A. Sánchez-Benítez

引用次数: 0