Lei Fang, Bo Zhang, Li Yan, Jian Dai, Weidong Wang, Q. Xie, Jing Li
{"title":"A new solution of time synchronization in all-digital PET based on TDC","authors":"Lei Fang, Bo Zhang, Li Yan, Jian Dai, Weidong Wang, Q. Xie, Jing Li","doi":"10.1109/NSSMIC.2015.7581850","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581850","url":null,"abstract":"High-accuracy time synchronization is one of the most important issues for basic detector modules (BDMs) in the all-digital PET. The existing synchronization solutions are hard to extend as strict requirement to the wires and interfaces. Once the number of BDM changed, the whole system's synchronization should be rebuilt from the beginning. In this paper, a new high-accuracy time-sync solution based on TDC with a feature of flexible extensible has been designed and implemented. It provides a protocol for time correction by any of two detectors through a simple communication: Each TDC implemented in every detector will record the accurate time of both the ASK and REPLY messages and sends the time-records to the other. By the exchange of time-records, the two detectors will calculate the time differences and correct it to for time synchronization. This method promise a lower requirement to the interfaces, and much simpler connecting and easier to be extended. And it can always offer a high accuracy time synchronization by just a soft correction, despite of the change or development of the PET system such as increasing or decreasing detectors.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121080284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brian J. Lee, Alexander M. Grant, Chen-Ming Chang, C. Levin
{"title":"Investigation of RF field penetrability of a novel electrically floating PET insert for PET/MR","authors":"Brian J. Lee, Alexander M. Grant, Chen-Ming Chang, C. Levin","doi":"10.1109/NSSMIC.2015.7582092","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582092","url":null,"abstract":"Combined positron emission tomography (PET) and magnetic resonance imaging (MRI) has shown potential to provide a powerful tool for disease characterization as it enables the simultaneous measurement of molecular, functional and anatomical information of the body. However, the availability of whole-body simultaneous PET/MRI has been limited by its high cost. To address this issue, we have developed an RF-penetrable PET technology that can be inserted into an MRI system without requiring modifications to the MR hardware. The prototype PET insert consists of 16 PET detector modules in a 32 cm ring pattern with 1 mm inter-modular gaps. By using electro-optical coupling technology, and batteries for power, the PET insert is electrically floating relative to the MRI RF ground which allows the RF field transmitted from the built-in body coil to penetrate through the PET ring. We performed experiments with various configurations to study the RF-penetrability of the PET insert in the MR system: No PET insert, with PET insert (powered with batteries), with PET ring gaps blocked with copper conductor but ends open, and with PET inserted, ends blocked with copper conductor but gaps open. With these configurations, we acquired B1 maps and performed electromagnetic simulations. We then compared the magnitude and homogeneity of the acquired B1 maps and simulation results. We have found that negligible amount of RF field enters through the gaps with the ends blocked, but this contributes to increasing the uniformity by ~400% when ends and gaps are both open. Then, the electromagnetic simulations show that by either decreasing the detector height and/or widening the inter-module gaps improve the RF-penetrability by nearly 300%.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121151477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of the trigger readout system for the phase-I upgrade of the ATLAS Liquid Argon calorimeters","authors":"H. Xu","doi":"10.1109/NSSMIC.2015.7581793","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581793","url":null,"abstract":"The ATLAS Liquid Argon (LAr) Calorimeters were designed and built to measure electromagnetic and hadronic energy in proton-proton collisions produced at the LHC at centre-of-mass energies up to 14 TeV and at instantaneous luminosities up to 1034cm-2s-1. An LHC upgrade is planned to enhance the luminosities to 2-3×1034cm-2s-1 and to deliver an integrated luminosity of about 300 fb-1 during Run 3 from 2021 through 2023. In order to improve the identification performance for electrons, photons, taus, jets, missing energy at high background rejection rates, an improved spatial granularity of the trigger primitives has been proposed. A new trigger readout system is being designed to digitize and process the signals with higher spatial granularity. A demonstrator system has been developed and installed on the ATLAS detector to evaluate the technical and performance aspects. Analog signal parameters including noise and cross-talk have been analyzed. The performance of the new demonstrator system in the data taking run will be presented. The next generation of prototypes for the trigger readout system is being developed. In this paper, research and development of radiation tolerant custom ASICs for the final trigger readout system will be discussed.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124860590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Summing of dynamic sinograms","authors":"Chuanyu Zhou, W. K. Luk, M. Casey","doi":"10.1109/NSSMIC.2015.7582061","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582061","url":null,"abstract":"There have been recent growing interests in dynamic FDG whole-body imaging. This current effort was initiated to facilitate and support this emergent trend. Summing dynamic sinograms to create a corresponding static frame may open the possibility of obtaining both dynamic and static data in one scan.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125306881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The building blocks for the upgrade of the LHCb RICH detectors","authors":"C. Gotti","doi":"10.1109/NSSMIC.2015.7581962","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581962","url":null,"abstract":"The RICH detectors of the LHCb experiment at CERN will undergo a major upgrade in the next years. A key element of the LHCb upgrade programme is to increase the readout rate of the whole detector from the current value of 1 MHz to 40 MHz. The photon detectors will be replaced with multi-anode photomultiplier tubes, read out with a new custom front-end ASIC, the CLARO8, tailored for high rate single photon counting. The layout of the system was designed to minimise parasitic capacitance at the anodes, resulting in very low noise and low crosstalk.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125336438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Volume visualization using adaptive tetrahedral mesh with GPU-accelerated fast cell search","authors":"A. Kimura, Satoshi Tanaka","doi":"10.1109/NSSMIC.2015.7581930","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581930","url":null,"abstract":"Tracking particles in a complex geometry of such a human body is an issue for the fast calculation of Monte Carlo simulations. An adaptive tetrahedral mesh is a solution for representing the complex geometry. The number of cells affects the calculation speed because of searching cells. However, the cell search is an issue for the calculation speed. Therefore, a GPU-accelerated fast cell search algorithm for the adaptive tetrahedral mesh has been developing. The adaptive tetrahedral mesh generation is described. The GPU-accelerated fast search of cells in the tetrahedral mesh has been developing. The volume visualization software has been also developing for visualizing outcomes of a Monte Carlo radiation simulation.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114887144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadia Jurgensen, L. Arpin, H. Bouziri, L. Njejimana, K. Koua, Émilie Gaudin, J. Pratte, R. Lecomte, R. Fontaine
{"title":"Initial results for automatic calibration of the LabPET II front-end detector module","authors":"Nadia Jurgensen, L. Arpin, H. Bouziri, L. Njejimana, K. Koua, Émilie Gaudin, J. Pratte, R. Lecomte, R. Fontaine","doi":"10.1109/NSSMIC.2015.7582076","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582076","url":null,"abstract":"An automatic calibration process for the LabPET II detector front-end module has been developed. By aiming at sub-millimetric spatial resolution, an unprecedented channel density is reached. The new detector front-end module is based on an application-specific integrated circuit (ASIC) implementing a Time-over-Threshold (ToT) scheme to extract both energy and time information. Consequently manual channel calibration becomes a tedious task and an automatic calibration strategy adapted to the ToT scheme is required to cope with the huge number and complexity of detector channels. The calibration process involves four main tasks: Clock Phase Adjustment, Photopeak Alignment, Timing Optimization and Energy Correction. To grant an easy and frequent adjustment, the calibration routine must be automatic and real-time. It was implemented in VHDL and C on a Microblaze microprocessor core embedded in a field programmable gate array (FPGA). Misalignment between channels were reduced after calibration from 17% FWHM to 6% FWHM.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115055198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wei Wei, Jie Zhang, Z. Ning, Yun-Ju Lu, L. Fan, Huai-shen Li, Xiaoshan Jiang, A. K. Lan, Q. Ouyang, Z. Wang, K. Zhu, Yuan-bo Chen, Peng Liu
{"title":"A high frame rate pixel readout chip design for synchrotron radiation applications","authors":"Wei Wei, Jie Zhang, Z. Ning, Yun-Ju Lu, L. Fan, Huai-shen Li, Xiaoshan Jiang, A. K. Lan, Q. Ouyang, Z. Wang, K. Zhu, Yuan-bo Chen, Peng Liu","doi":"10.1109/NSSMIC.2015.7582280","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582280","url":null,"abstract":"A hybrid pixel detector working in the single photon counting mode was designed for the High Energy Photon Source (HEPS) in China. Aiming for diffraction and protein crystallography applications, the pixel readout chip works in single photon counting mode in each pixel. It contains an array of 104 × 72 pixels with a pixel size of 150μm×150 μm, each owning a counting depth of 20bits. Different from the conventional readout structure based on the pseudo-random counter, an independent shift register chain was inserted, separated with the counter. Therefore this design allows high frame rate counting and data transfer simultaneously. The chip measurement showed 94 e- equivalent noise and non-uniformity less than 55 e-after threshold equalization. All functions were proved to be normal at a frame rate of 1.2 kHz with a negligible dead-time, which are greatly improved compared with the existing pixel system.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116126637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experiment research on liquid security screening with energy dispersive X-ray diffraction","authors":"Tianyi Yangdai, Li Zhang","doi":"10.1109/NSSMIC.2015.7581755","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7581755","url":null,"abstract":"Recently, more attentions are paid on liquid security screening, and XRD proves to have great capability to distinguish liquid contrabands from daily supplies. In this study, we set up an Energy Dispersive X-ray Diffraction (EDXRD) test bed facility, and conduct many tests on dozens of liquid samples. Results show the great potential of the XRD for liquid contrabands classification, and XRD's advantages toward traditional CT techniques in some cases. Other experiments on ethanol aqueous solutions with different concentration show the possibility to calculate the concentration of aqueous solution based on XRD spectra. There is a significant difference between liquid contrabands and daily supplies in the terms of main peak positions, which indicates that the main peak position of the XRD spectra would be an effective probe to detect liquid contrabands.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123018536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xinyue Zhang, Yinlin Li, R. Sánchez-Jurado, A. Pardo, Andrew M. Polemi, Antonio J. González, J. Alamo, J. Ferrer, S. Majewski, B. Kundu
{"title":"Segmentation method for breast tumor diagnosis based on Artificial Neural Network algorithm applied to dynamic 18F-FDG PET images","authors":"Xinyue Zhang, Yinlin Li, R. Sánchez-Jurado, A. Pardo, Andrew M. Polemi, Antonio J. González, J. Alamo, J. Ferrer, S. Majewski, B. Kundu","doi":"10.1109/NSSMIC.2015.7582056","DOIUrl":"https://doi.org/10.1109/NSSMIC.2015.7582056","url":null,"abstract":"To establish an accurate and automatic image segmentation method for extracting the tumor from the healthy tissue using the dedicated 18F-FDG Mammography with Molecular Imaging (MAMMI) Positron Emission Tomography (PET) dynamic images of breast in vivo, the paper presents a novel method using Artificial Neural Network (ANN) combined with time activity curves (TAC) of each voxel as input vector. TACs voxel by voxel were obtained from PET images with average filtering and least-squares fitting algorithm to improve the signal noise ratio (SNR). The data was then normalized and constructed as input feature vectors of the ANN network to train or segment the tumor regions. The initial pilot validation with 2 patient's data of the proposed method using FDG has shown promising results.","PeriodicalId":106811,"journal":{"name":"2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114180092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}