{"title":"Renal prostaglandin production in the Japanese (Kyoto) spontaneously hypertensive rat.","authors":"M J Dunn","doi":"10.1042/cs055191s","DOIUrl":"https://doi.org/10.1042/cs055191s","url":null,"abstract":"1. Renal venous and urinary prostaglandin E2 (PGE2) and prostaglandin F2alpha (PGF2alpha) were measured in spontaneously hypertensive (SH) rats and Wistar-Kyoto normotensive rats (WKy) of 4 different ages, ranging from 4 to 54 weeks. 2. Renal venous (plasma) PGE2 and PGF2alpha were similar in WKy and SH rats at all ages, except for greater PGF2alpha in 40-54 week old SH rats. 3. Urinary (24 h) PGE2 and PGF2alpha were similar in WKy and SH rats at all ages, except for greater PGE2 in 7-12 week old SH rats. 4. There was a significant trend for renal venous and urinary PGE2 and PGF2alpha to decrease with advancing age. 5. These experiments did not show evidence that the SH rat kidney, in vivo, has an abnormality of PGE2 or PGF2alpha production or degradation, which alters secretion or excretion of either prostaglandin.","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"191s-193s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055191s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11495157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of nurse practitioners in hypertension care.","authors":"K Soghikian","doi":"10.1042/cs055345s","DOIUrl":"https://doi.org/10.1042/cs055345s","url":null,"abstract":"<p><p>1. Two groups of hypertensive patients, randomly assigned to either physician or nurse practitioner care, were compared, after two years of follow up, with respect to diastolic blood pressure reduction and utilization and costs of medical services. In addition, satisfaction with hypertension are was evaluated. 2. There was no statistical difference in mean diastolic blood pressure reduction between the physician and nurse practitioner groups. 3. Patients in the nurse practitioner group made more visits for hypertension care than those in the physician group; thus, even though the cost per nurse practitioner visit was lower than the cost per physician visit, the total annual cost of care per patient was higher in the nurse practitioner group. 4. Patients followed by nurse practitioners were very satisfied with their care. 5. Nurse practitioners provide excellent hypertension care and thereby save valuable physician time.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"345s-358s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055345s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blood pressure control: the effect of facilitated access to treatment.","authors":"M H Alderman, K F Miller","doi":"10.1042/cs055349s","DOIUrl":"https://doi.org/10.1042/cs055349s","url":null,"abstract":"<p><p>1. Effectiveness of hypertension care has been compared in patients treated at a Union health centre and at their place of work. 2. Patient adherence and blood pressure control is not affected by the place of treatment. 3. A systematic approach to treatment can be successful in a large population group.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"349s-351s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055349s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of vasopressin in blood pressure control of spontaneously hypertensive rats.","authors":"J Möhring, J Kintz, J Schoun","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"246s-250s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M H Maxwell, P Varady, E T Zawada, J F Burkhalter, U Waks, L Marks
{"title":"Maximal discrimination of renovascular from essential hypertension by the saralasin test.","authors":"M H Maxwell, P Varady, E T Zawada, J F Burkhalter, U Waks, L Marks","doi":"10.1042/cs055297s","DOIUrl":"https://doi.org/10.1042/cs055297s","url":null,"abstract":"","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"297s-299s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055297s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nomenclature of experimental renal hypertension. Report of the Nomenclature Committee of the International Society of Hypertension.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"211s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B L Bean, J J Brown, J Casals-Stenzel, R Fraser, A F Lever, J J Morton, B Petch, A J Riegger, J I Robertson, M Tree
{"title":"An altered relation between arterial pressure and plasma angiotensin II concentration resulting from prolonged infusion of angiotensin II.","authors":"B L Bean, J J Brown, J Casals-Stenzel, R Fraser, A F Lever, J J Morton, B Petch, A J Riegger, J I Robertson, M Tree","doi":"10.1042/cs055217s","DOIUrl":"https://doi.org/10.1042/cs055217s","url":null,"abstract":"<p><p>1. Infusion of angiotensin II into dogs at constant dose over 2 weeks caused a progressive rise in arterial pressure. 2. When the infusion was stopped the pressure dropped slowly from hypertensive levels over 48 h. 3. Dose-response studies at weekly intervals showed progressive elevation, without steepening, of the plasma angiotensin II-blood pressure curve. 4. Thus, during prolonged administration of angiotensin II, a given plasma concentration of the peptide can sustain a higher arterial pressure than it can during acute infusions.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"217s-220s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055217s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J O Davis, G A Stephens, R H Freeman, J M Deforrest
{"title":"Changes in cardiac output during the development of renal hypertension in sodium-depleted dogs.","authors":"J O Davis, G A Stephens, R H Freeman, J M Deforrest","doi":"10.1042/cs055221s","DOIUrl":"https://doi.org/10.1042/cs055221s","url":null,"abstract":"<p><p>1. Chronic renovascular hypertension developed in uninephrectomized, sodium-depleted dogs in association with a decrease in cardiac output. 2. With sodium and volume repletion of these animals, cardiac output returned to normal but the high level of arterial pressure was unchanged; consequently, the peripheral arterioles dilated. 3. These observations provide evidence against the theory of whole-body autoregulation.</p>","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"221s-223s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055221s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11496270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Closing address: au revoir et à bientôt.","authors":"J I Robertson","doi":"10.1042/cs055409s","DOIUrl":"https://doi.org/10.1042/cs055409s","url":null,"abstract":"","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"4 ","pages":"409s-412s"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs055409s","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11575148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The isolated perfused rat kidney.","authors":"B D Ross","doi":"10.1042/cs0550513","DOIUrl":"https://doi.org/10.1042/cs0550513","url":null,"abstract":"","PeriodicalId":10672,"journal":{"name":"Clinical science and molecular medicine. Supplement","volume":"55 6","pages":"513-21"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1042/cs0550513","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11255662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}