Clinical Neurophysiology最新文献

Diagnosis of carpal tunnel syndrome using deep learning with comparative guidance 比较指导下深度学习诊断腕管综合征

IF 3.7 3区医学

Clinical Neurophysiology Pub Date : 2025-04-22 DOI: 10.1016/j.clinph.2025.03.038

Jungsub Sim , Sungche Lee , Seunghyun Kim , Seong-ho Jeong , Joonshik Yoon , Seungjun Baek

{"title":"Diagnosis of carpal tunnel syndrome using deep learning with comparative guidance","authors":"Jungsub Sim , Sungche Lee , Seunghyun Kim , Seong-ho Jeong , Joonshik Yoon , Seungjun Baek","doi":"10.1016/j.clinph.2025.03.038","DOIUrl":"10.1016/j.clinph.2025.03.038","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to develop a deep learning model for a robust diagnosis of Carpal Tunnel Syndrome (CTS) based on comparative classification leveraging the ultrasound images of the thenar and hypothenar muscles.</div></div><div><h3>Methods</h3><div>We recruited 152 participants, both patients with varying severities of CTS and healthy individuals. The enrolled patients underwent ultrasonography, which provided ultrasound image data of the thenar and hypothenar muscles from the median and ulnar nerves. These images were used to train a deep learning model. We compared the performance of our model with previous comparative methods using echo intensity ratio or machine learning, and non-comparative methods based on deep learning. During the training process, comparative guidance based on cosine similarity was used so that the model learns to automatically identify the abnormal differences in echotexture between the ultrasound images of the thenar and hypothenar muscles.</div></div><div><h3>Results</h3><div>The proposed deep learning model with comparative guidance showed the highest performance. The comparison of Receiver operating characteristic (ROC) curves between models demonstrated that the Comparative guidance was effective in autonomously identifying complex features within the CTS dataset.</div></div><div><h3>Conclusions</h3><div>The proposed deep learning model with comparative guidance was shown to be effective in automatically identifying important features for CTS diagnosis from the ultrasound images. The proposed comparative approach was found to be robust to the traditional problems in ultrasound image analysis such as different cut-off values and anatomical variation of patients.</div></div><div><h3>Significance</h3><div>Proposed deep learning methodology facilitates accurate and efficient diagnosis of CTS from ultrasound images.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"174 ","pages":"Pages 191-197"},"PeriodicalIF":3.7,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DICOM encoding of annotation and montage data for waveform recordings DICOM编码的注释和蒙太奇数据的波形记录

IF 3.7 3区医学

Clinical Neurophysiology Pub Date : 2025-04-21 DOI: 10.1016/j.clinph.2025.04.002

J.J. Halford , B.A. Brinkmann , S. Rampp , J. Rémi , S. Poznikoff , K.B. Nilsen , J.A. Ehrenberg , S. Winkler

引用次数: 0

Systematic comparison of Commercial seizure detection Software: Update equals Upgrade? 商用查封检测软件的系统比较：更新等于升级？

IF 3.7 3区医学

Clinical Neurophysiology Pub Date : 2025-04-21 DOI: 10.1016/j.clinph.2025.04.003

Johannes Koren , Kady Colabrese , Manfred Hartmann , Moritz Feigl , Clemens Lang , Sebastian Hafner , Nicolas Nierenberg , Tilmann Kluge , Christoph Baumgartner

{"title":"Systematic comparison of Commercial seizure detection Software: Update equals Upgrade?","authors":"Johannes Koren , Kady Colabrese , Manfred Hartmann , Moritz Feigl , Clemens Lang , Sebastian Hafner , Nicolas Nierenberg , Tilmann Kluge , Christoph Baumgartner","doi":"10.1016/j.clinph.2025.04.003","DOIUrl":"10.1016/j.clinph.2025.04.003","url":null,"abstract":"<div><h3>Objective</h3><div>To compare two updated commercially available seizure detection software packages (encevis 2.0 and Persyst 14) in a large video-EEG monitoring dataset comprising 80 patients with 6826 h of EEG and 912 seizures.</div></div><div><h3>Methods</h3><div>We conducted a follow up study of two seizure detection software packages with a significant update since 2021 using different sensitivity settings.</div></div><div><h3>Results</h3><div>Mean overall seizure count was 11.4 and mean tonic-clonic seizure rate was 0.7 per patient. Detection rates (DR) per patient were 80.7% to 89.1% for encevis 2.0 and 67.3% to 71.1% for Persyst 14. False positive rates (FPR) per day were 12 to 22 for encevis 2.0 and 2 to 4 for Persyst 14.</div></div><div><h3>Conclusions</h3><div>Encevis 2.0 showed a significantly higher DR than Persyst 14, whereas Persyst 14 showed a significantly lower FPR than encevis 2.0.</div></div><div><h3>Significance</h3><div>Updated FDA and CE certified seizure detection software showed opposite changes: encevis improved in sensitivity and deteriorated in FPR, while Persyst improved in FPR and deteriorated in sensitivity. In agreement with previous publications, automatic seizure detection software is ready for routine clinical use, but specialized personnel with sound neurophysiological knowledge and awareness of the strengths and weaknesses of the specific software package used is critical.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"174 ","pages":"Pages 178-188"},"PeriodicalIF":3.7,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neural Correlates of taVNS: Scalp EEG and insular sEEG heartbeat evoked potentials modulation in an Epileptic patient case study taVNS的神经关联：一个癫痫患者的头皮脑电图和岛岛sEEG心跳诱发电位调节病例研究

IF 3.7 3区医学

Clinical Neurophysiology Pub Date : 2025-04-20 DOI: 10.1016/j.clinph.2025.04.013

Enrique Germany Morrison , Manon Dumoulin , Vincent Joris , Roberto Santalucia , Venethia Danthine , Inci Cakiroglu , Giulia Liberati , Antoine Nonclercq , Riëm El Tahry

引用次数: 0

Enhancing diagnostic sensitivity in Myasthenia Gravis: The combined role of CMAP area and amplitude decrements in repetitive nerve stimulation 增强重症肌无力的诊断敏感性：CMAP区域和振幅下降在重复神经刺激中的联合作用

IF 3.7 3区医学

Clinical Neurophysiology Pub Date : 2025-04-20 DOI: 10.1016/j.clinph.2025.04.004

Ângelo Fonseca , Marco Almeida , Cristina Duque , Luís Negrão , Anabela Matos , Luciano Almendra

{"title":"Enhancing diagnostic sensitivity in Myasthenia Gravis: The combined role of CMAP area and amplitude decrements in repetitive nerve stimulation","authors":"Ângelo Fonseca , Marco Almeida , Cristina Duque , Luís Negrão , Anabela Matos , Luciano Almendra","doi":"10.1016/j.clinph.2025.04.004","DOIUrl":"10.1016/j.clinph.2025.04.004","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the diagnostic utility of using CMAP area decrement, in addition to CMAP amplitude decrement, in RNS testing for patients with suspected MG.</div></div><div><h3>Methods</h3><div>This retrospective study analyzed EMG data from January 2019 to December 2023 on patients with suspected MG. CMAP area and amplitude decrements of ≥10 % were considered abnormal, and MG diagnosis was based on clinical presentation, antibody testing, or response to treatment.</div></div><div><h3>Results</h3><div>A total of 204 patients were included in the final analysis. MG was diagnosed in 71 patients (29.8%). The sensitivity of the amplitude decrement was 29.6%, while the sensitivity of the area decrement was 38%, with specificities of 99.2% and 96.12%, respectively. Combining both criteria yielded a sensitivity of 43.7%, representing a 14.1% improvement over amplitude decrement alone.</div></div><div><h3>Conclusion</h3><div>Incorporating CMAP area decrement into RNS testing significantly enhances diagnostic sensitivity for MG, particularly in ocular forms, without compromising specificity. This combined approach presents a promising improvement over existing diagnostic tools for MG, especially in cases where traditional methods have limitations. Future research is needed to validate these findings.</div></div><div><h3>Significance</h3><div>This study introduces a practical and easy to adopt enhancement to repetitive nerve stimulation, significantly improving diagnostic sensitivity for Myasthenia Gravis.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"174 ","pages":"Pages 169-172"},"PeriodicalIF":3.7,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A single session of motor imagery paired with spinal stimulation improves manual dexterity and increases cortical excitability after spinal cord injury 单次运动想象配合脊髓刺激可改善脊髓损伤后的手灵巧性和增加皮质兴奋性

IF 3.7 3区医学

Clinical Neurophysiology Pub Date : 2025-04-20 DOI: 10.1016/j.clinph.2025.03.047

Antonio Capozio , Madison Graham , Ronaldo Ichiyama , Sarah L. Astill

{"title":"A single session of motor imagery paired with spinal stimulation improves manual dexterity and increases cortical excitability after spinal cord injury","authors":"Antonio Capozio , Madison Graham , Ronaldo Ichiyama , Sarah L. Astill","doi":"10.1016/j.clinph.2025.03.047","DOIUrl":"10.1016/j.clinph.2025.03.047","url":null,"abstract":"<div><h3>Objective</h3><div>Non-invasive stimulation of the spinal cord at the cervical level (TSCS) can induce neural plasticity and improve upper limb function in people living with cervical spinal cord injury (SCI) when paired with task practice. The aim of this study was to investigate the effects of a session of motor imagery (MI) paired with TSCS on manual dexterity, corticospinal and spinal excitability in people living with cervical SCI.</div></div><div><h3>Methods</h3><div>Eight participants (4 females, mean age 46yrs ± 17) completed three sessions of: 1) MI; 2) TSCS at C5–C6 level; 3) MI + TSCS, listening to the MI script while receiving TSCS. Manual dexterity was assessed with the Purdue Pegboard Test (PPT), corticospinal excitability was assessed with Transcranial Magnetic Stimulation (TMS) delivered at motor threshold and suprathreshold (120 % intensities, and spinal excitability delivered at motor threshold and suprathreshold (110 %, 120 %) intensities was assessed with single pulses of TSCS.</div></div><div><h3>Results</h3><div>Manual dexterity increased from baseline after all three conditions (p = 0.016). Corticospinal excitability increased from baseline after MI (p = 0.002] and MI + TSCS (p = 0.031], but not TSCS (p = 0.343). Spinal excitability was not affected by any of the conditions (p = 0.425).</div></div><div><h3>Conclusions</h3><div>These findings demonstrate that a single session of MI and TSCS, either alone or in combination, can increase manual dexterity in people living with cervical SCI. The increase in dexterity was paralleled by increases in corticospinal excitability for the MI and MI + TSCS conditions.</div></div><div><h3>Significance</h3><div>Our findings indicate that MI and TSCS improve manual dexterity and increase corticospinal excitability in people living with cervical SCI when employed in isolation or in combination.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"174 ","pages":"Pages 160-168"},"PeriodicalIF":3.7,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Altered electroencephalography-based source functional connectivity in patients with generalized anxiety disorder 广泛性焦虑障碍患者基于脑电图的源功能连通性改变

IF 3.7 3区医学

Clinical Neurophysiology Pub Date : 2025-04-20 DOI: 10.1016/j.clinph.2025.04.014

Che-Sheng Chu , Yen-Yue Lin , Cathy Chia-Yu Huang , Yong-An Chung , Sonya Youngju Park , Wei-Chou Chang , Chuan-Chia Chang , Hsin-An Chang

{"title":"Altered electroencephalography-based source functional connectivity in patients with generalized anxiety disorder","authors":"Che-Sheng Chu , Yen-Yue Lin , Cathy Chia-Yu Huang , Yong-An Chung , Sonya Youngju Park , Wei-Chou Chang , Chuan-Chia Chang , Hsin-An Chang","doi":"10.1016/j.clinph.2025.04.014","DOIUrl":"10.1016/j.clinph.2025.04.014","url":null,"abstract":"<div><h3>Objective</h3><div>To explore the neurophysiological markers of generalized anxiety disorder (GAD), we performed electroencephalography (EEG) in patients with GAD and assessed lagged phase synchronization (LPS), a measure of brain functional connectivity (FC).</div></div><div><h3>Methods</h3><div>Cortical EEG sources were modelled by exact low resolution brain electromagnetic tomography (eLORETA). Graph theory analyses were applied to undirected and weighted networks obtained by LPS to explore the FC differences between patients with GAD and controls. The association between the abnormal parameters and disease symptomatology was examined.</div></div><div><h3>Results</h3><div>Compared to controls (n = 89), the GAD group (n = 104) showed higher brain connectivity in beta-2 (18.5–21 Hz) between the left cingulate gyrus and the right postcentral gyrus (PcG) and in beta-3 (21.5–30 Hz) between the brain hemispheres in several regions, particularly the left PcG. Patients with GAD showed higher global network efficiency in beta-3. Finally, a positive correlation was observed between a longer duration of illness and greater FC in beta-2 between brain regions.</div></div><div><h3>Conclusions</h3><div>The present findings suggest that EEG-sourced measures are useful tools for understanding altered brain connectivity in GAD.</div></div><div><h3>Significance</h3><div>EEG could be a valuable biomarker in differentiating patients with GAD from controls and could be a potential predictive tool in future studies.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"175 ","pages":"Article 2010736"},"PeriodicalIF":3.7,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cortical plasticity, therapeutic effects, and neural circuit activity of angular gyrus rTMS in amnestic mild cognitive impairment 角回rTMS治疗健忘轻度认知障碍的皮质可塑性、治疗效果和神经回路活动

IF 3.7 3区医学

Clinical Neurophysiology Pub Date : 2025-04-18 DOI: 10.1016/j.clinph.2025.04.012

Ya Chen , Xinle Hou , Huijuan Zhou , Tingyu Lv , Ruichen Han , Zhiyuan Yang , Wenao Zheng , Feng Bai

{"title":"Cortical plasticity, therapeutic effects, and neural circuit activity of angular gyrus rTMS in amnestic mild cognitive impairment","authors":"Ya Chen , Xinle Hou , Huijuan Zhou , Tingyu Lv , Ruichen Han , Zhiyuan Yang , Wenao Zheng , Feng Bai","doi":"10.1016/j.clinph.2025.04.012","DOIUrl":"10.1016/j.clinph.2025.04.012","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to explore the neurophysiological mechanisms behind the improvement of cognitive functions through angular gyrus repetitive transcranial magnetic stimulation (rTMS) in patients with amnestic mild cognitive impairment (aMCI) by assessing cortical plasticity, underscoring the predictive value of cortical plasticity for clinical outcomes.</div></div><div><h3>Methods</h3><div>Twenty-seven aMCI patients were allocated to the intervention and control groups for 4 weeks of 20 Hz rTMS of the angular gyrus. Long-term potentiation (LTP)-like cortical plasticity in the motor M1 area, in conjunction with neuropsychological tests and resting-state brain imaging, was used to investigate the mechanism behind angular gyrus rTMS.</div></div><div><h3>Results</h3><div>At baseline, aMCI patients presented impaired LTP-like motor cortical plasticity related to cognitive damage. Following treatment with angular gyrus rTMS, a reversal in the impairment of this plasticity was observed. This improvement was associated with clinical efficacy in terms of cognitive function and changes in the resting-state brain network activities of the sensorimotor, default mode, and frontoparietal networks.</div></div><div><h3>Conclusions</h3><div>Clinical symptoms are alleviated by angular gyrus rTMS, and damaged cortex plasticity also shows signs of improvement, potentially linked to transcortical neural activity across multiple brain regions in aMCI patients. Cortical plasticity induced by transcranial magnetic stimulation has potential value in predicting the clinical outcomes of neuromodulation.</div></div><div><h3>Significance</h3><div>Motor cortex plasticity may be related to cognitive function and therapeutic effects in aMCI patients and may be modulated by angular gyrus transcranial magnetic stimulation.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"174 ","pages":"Pages 198-211"},"PeriodicalIF":3.7,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional connectivity anomalies in medication-naive children with ADHD: Diagnostic potential, symptoms interpretation, and a mediation model 未接受药物治疗的ADHD儿童的功能连接异常：诊断潜力、症状解释和中介模型

IF 3.7 3区医学

Clinical Neurophysiology Pub Date : 2025-04-18 DOI: 10.1016/j.clinph.2025.04.011

Yingzi Hu , Yexian Zeng , Tong Fu , Danping Hong , Han Yang , Zhihang Zhu , Daomeng Cheng , Caiping Dang , Yan Song , Chanjuan Yang , Weizhen Yin , Yanling Zhou

{"title":"Functional connectivity anomalies in medication-naive children with ADHD: Diagnostic potential, symptoms interpretation, and a mediation model","authors":"Yingzi Hu , Yexian Zeng , Tong Fu , Danping Hong , Han Yang , Zhihang Zhu , Daomeng Cheng , Caiping Dang , Yan Song , Chanjuan Yang , Weizhen Yin , Yanling Zhou","doi":"10.1016/j.clinph.2025.04.011","DOIUrl":"10.1016/j.clinph.2025.04.011","url":null,"abstract":"<div><h3>Objective</h3><div>To identify reliable electroencephalography (EEG) biomarkers for attention deficit/hyperactivity disorder (ADHD) by investigating anomalous functional connectivity patterns and their clinical relevance.</div></div><div><h3>Methods</h3><div>Resting-state EEG data were collected from 74 children aged 6–12 (33 unmedicated ADHD; 41 typically developing). Functional connectivity was quantified using the imaginary part of coherency (ICOH). Machine learning (ML)-based support vector machine (SVM) modeling, regression, and mediation analyses linked connectivity features to symptom severity and diagnostic classification.</div></div><div><h3>Results</h3><div>Children with ADHD exhibited beta (β) band hypo-connectivity in frontal regions (Fp2-F4, Fp1-Cz, F7-Cz) and theta (θ) band hyper-connectivity in left parietal-central networks (C3-P7, P3-P7, etc.). An SVM classifier achieved an average area under the curve of 0.89 using three connectivity features. Left parietal θ band hyper-connectivity (C3-P7) correlated with both inattention and hyperactivity/impulsivity and mediated their interrelationship.</div></div><div><h3>Conclusions</h3><div>ADHD is characterized by disrupted frontoparietal connectivity, with θ band hyper-connectivity in sensory-integration networks potentially compensating for impaired frontal regulation.</div></div><div><h3>Significance</h3><div>These findings highlight C3-P7 θ band connectivity as both a diagnostic and mechanistic biomarker, providing novel target for neurofeedback therapies and enhancing the differential diagnosis in neurodevelopmental disorders.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"174 ","pages":"Pages 212-219"},"PeriodicalIF":3.7,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143886304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrodiagnostic characteristics of neuromuscular disease in paediatric intensive care 小儿重症监护中神经肌肉疾病的电诊断特点

IF 3.7 3区医学

Clinical Neurophysiology Pub Date : 2025-04-17 DOI: 10.1016/j.clinph.2025.04.005

Laura Nastasi , Amjad Aldrees , Daniyal Motan , Sheba Azam , Matthew Pitt , Gerald Cooray , Jacquie Deeb

{"title":"Electrodiagnostic characteristics of neuromuscular disease in paediatric intensive care","authors":"Laura Nastasi , Amjad Aldrees , Daniyal Motan , Sheba Azam , Matthew Pitt , Gerald Cooray , Jacquie Deeb","doi":"10.1016/j.clinph.2025.04.005","DOIUrl":"10.1016/j.clinph.2025.04.005","url":null,"abstract":"<div><h3>Objective</h3><div>Assessing peripheral electrodiagnostic (EDX) tests in paediatric intensive care.</div></div><div><h3>Methods</h3><div>Data from patients who had undergone EDX test/s between 2010 and 2019 at a tertiary centre were retrospectively analysed, including final neuromuscular diagnoses, EDX results and demographic information. EDX data included motor and sensory nerve conduction study, needle electromyography (EMG), repetitive nerve stimulation and stimulated single fiber EMG. Final clinical diagnosis was based on several investigations including muscle biopsy, MR imaging, gene testing, EDX-tests and clinical phenotype.</div></div><div><h3>Results</h3><div>351 patients were identified (56 % male, average age 42.5 months), with diagnoses categorised into the following groups: no identifiable neuromuscular disorders (45 %), neuropathy (13 %), motor neuron disease (9 %), isolated bulbar palsy (6 %), myopathy (14 %), neuromuscular junction disorders (5 %), and critical illness neuromyopathy (8 %). EDX data was stratified into 7 electrodiagnostic categories: normal, neuropathy, motor neuron disease, isolated bulbar palsy, myopathy, neuromuscular junction disorders, and critical illness neuromyopathy. With this stratification we were able to predict the final diagnosis with acceptable accuracy.</div></div><div><h3>Conclusion</h3><div>The prevalence of neuromuscular disease groups in paediatric ICU was defined together with their corresponding EDX characteristics.</div></div><div><h3>Significance</h3><div>The study confirms the utility of electrophysiology as a valuable tool for diagnosing and managing neuromuscular conditions in paediatric ICU.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"174 ","pages":"Pages 123-130"},"PeriodicalIF":3.7,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0