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Clinical Neurophysiology最新文献

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Neuroprotective effects of deep brain stimulation and physical exercise via immune modulation in a mouse model of progressive Parkinson’s disease 脑深部刺激和体育锻炼通过免疫调节对进行性帕金森病小鼠模型的神经保护作用
IF 3.6 3区 医学
Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110879
Alexander Grotemeyer , Tobias Petschner , Rhonda McFleder , Ibrahim Ucar , Sophie Steinhauser , Robert Peach , Jens Volkmann , Chi Wang Ip
{"title":"Neuroprotective effects of deep brain stimulation and physical exercise via immune modulation in a mouse model of progressive Parkinson’s disease","authors":"Alexander Grotemeyer , Tobias Petschner , Rhonda McFleder , Ibrahim Ucar , Sophie Steinhauser , Robert Peach , Jens Volkmann , Chi Wang Ip","doi":"10.1016/j.clinph.2025.2110879","DOIUrl":"10.1016/j.clinph.2025.2110879","url":null,"abstract":"","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2110879"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Propionic acid activates anti-inflammatory processes and induces adult phenotype changes in Schwann cells 丙酸激活抗炎过程，诱导雪旺细胞成体表型改变
IF 3.6 3区 医学
Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110887
Niklas Rilke , Maximilian Schütte , Mona Shaygan Tabar , Finn Specht , Baffour Sarpong , Katharina Lehmhöfer , Melissa Sgodzai , Alina Blusch , Lea Joswig , Anna Meichsner , Anna Lena Fisse , Jeremias Motte , Britta Eggers , Katrin Marcus , Konstanze Winklhofer , Thomas Grüter , Ralf Gold , Kalliopi Pitarokoili
{"title":"Propionic acid activates anti-inflammatory processes and induces adult phenotype changes in Schwann cells","authors":"Niklas Rilke , Maximilian Schütte , Mona Shaygan Tabar , Finn Specht , Baffour Sarpong , Katharina Lehmhöfer , Melissa Sgodzai , Alina Blusch , Lea Joswig , Anna Meichsner , Anna Lena Fisse , Jeremias Motte , Britta Eggers , Katrin Marcus , Konstanze Winklhofer , Thomas Grüter , Ralf Gold , Kalliopi Pitarokoili","doi":"10.1016/j.clinph.2025.2110887","DOIUrl":"10.1016/j.clinph.2025.2110887","url":null,"abstract":"","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2110887"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of the subitem hand function in the German version of the stroke impact scale 德文版冲程冲击量表子项手功能的验证
IF 3.6 3区 医学
Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110892
Kristin Starke, Ameli Aden, Anika Stockert, Sophie Meixensberger, Dorothee Saur
{"title":"Validation of the subitem hand function in the German version of the stroke impact scale","authors":"Kristin Starke, Ameli Aden, Anika Stockert, Sophie Meixensberger, Dorothee Saur","doi":"10.1016/j.clinph.2025.2110892","DOIUrl":"10.1016/j.clinph.2025.2110892","url":null,"abstract":"","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2110892"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine learning approach for voxel-wise prediction of basal and complex motor function after stroke 脑卒中后基础和复杂运动功能体素预测的机器学习方法
IF 3.6 3区 医学
Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110895
Eva Rickers , Frauke Esser , Elizabeth Rizor , Theresa Paul , Ellen Binder , Lukas Hensel , Anne Rehme , Corinna Ringmaier , Schönberger Anna , Caroline Tscherpel , Christian Grefkes-Hermann , Scott Grafton , Gereon R. Fink , Lukas Jan Volz
{"title":"Machine learning approach for voxel-wise prediction of basal and complex motor function after stroke","authors":"Eva Rickers , Frauke Esser , Elizabeth Rizor , Theresa Paul , Ellen Binder , Lukas Hensel , Anne Rehme , Corinna Ringmaier , Schönberger Anna , Caroline Tscherpel , Christian Grefkes-Hermann , Scott Grafton , Gereon R. Fink , Lukas Jan Volz","doi":"10.1016/j.clinph.2025.2110895","DOIUrl":"10.1016/j.clinph.2025.2110895","url":null,"abstract":"","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2110895"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left inferior parietal lobe and auditory cortex jointly contribute to sound knowledge retrieval 左侧下顶叶和听觉皮层共同参与声音知识检索
IF 3.6 3区 医学
Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110840
Philipp Kuhnke , Johannah Voeller , Vincent Cheung , Ole Numssen , Konstantin Weise , Markus Kiefer , Gesa Hartwigsen
{"title":"Left inferior parietal lobe and auditory cortex jointly contribute to sound knowledge retrieval","authors":"Philipp Kuhnke , Johannah Voeller , Vincent Cheung , Ole Numssen , Konstantin Weise , Markus Kiefer , Gesa Hartwigsen","doi":"10.1016/j.clinph.2025.2110840","DOIUrl":"10.1016/j.clinph.2025.2110840","url":null,"abstract":"","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2110840"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of relapses after meningococcal vaccination in clinical trials and real-world evidence of eculizumab and ravulizumab in AQP4-Ab+ NMOSD 在AQP4-Ab+ NMOSD中，临床试验中脑膜炎球菌疫苗接种后复发的发生率和eculizumab和ravulizumab的真实证据
IF 3.6 3区 医学
Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110837
Alexandra Zuk , Sami Fam , Becky Parks , Kerstin Allen
{"title":"Incidence of relapses after meningococcal vaccination in clinical trials and real-world evidence of eculizumab and ravulizumab in AQP4-Ab+ NMOSD","authors":"Alexandra Zuk , Sami Fam , Becky Parks , Kerstin Allen","doi":"10.1016/j.clinph.2025.2110837","DOIUrl":"10.1016/j.clinph.2025.2110837","url":null,"abstract":"","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2110837"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and effectiveness of nipocalimab in adolescent participants in the open label phase 2/3 Vibrance-MG clinical study nipocalimab在开放标签2/3期Vibrance-MG临床研究中青少年参与者的安全性和有效性
IF 3.6 3区 医学
Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110868
Jonathan Strober , Shawn Black , Sindhu Ramchandren , Saunder Bernes , Akiyuki Uzawa , Yasuhiro Kimoto , Keiko Ishigaki , Tuan Vu , Dan Huang , Yaowei Zhu , Hong Sun , Sebastian Möller
{"title":"Safety and effectiveness of nipocalimab in adolescent participants in the open label phase 2/3 Vibrance-MG clinical study","authors":"Jonathan Strober , Shawn Black , Sindhu Ramchandren , Saunder Bernes , Akiyuki Uzawa , Yasuhiro Kimoto , Keiko Ishigaki , Tuan Vu , Dan Huang , Yaowei Zhu , Hong Sun , Sebastian Möller","doi":"10.1016/j.clinph.2025.2110868","DOIUrl":"10.1016/j.clinph.2025.2110868","url":null,"abstract":"","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2110868"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebellar transcranial direct current stimulation in Friedreich ataxia: Anatomy matters 小脑经颅直流电刺激治疗弗里德赖希共济失调：解剖学问题。
IF 3.6 3区 医学
Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110784
Roderick P.P.W.M. Maas , Dennis J.L.G. Schutter
{"title":"Cerebellar transcranial direct current stimulation in Friedreich ataxia: Anatomy matters","authors":"Roderick P.P.W.M. Maas , Dennis J.L.G. Schutter","doi":"10.1016/j.clinph.2025.2110784","DOIUrl":"10.1016/j.clinph.2025.2110784","url":null,"abstract":"","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2110784"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in the thalamocortical component of high frequency oscillations following botulinum toxin treatment in cervical dystonia 肉毒杆菌毒素治疗后颈肌张力障碍丘脑皮层高频振荡成分的变化。
IF 3.6 3区 医学
Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.03.048
Alessandro Cruciani , Gaia Anzini , Alessandro Magliozzi , Gabriella Musumeci , Daniel T. Corp , Maria Concetta Altavista , Vincenzo Di Lazzaro , Massimo Marano
{"title":"Changes in the thalamocortical component of high frequency oscillations following botulinum toxin treatment in cervical dystonia","authors":"Alessandro Cruciani ,&nbsp;Gaia Anzini ,&nbsp;Alessandro Magliozzi ,&nbsp;Gabriella Musumeci ,&nbsp;Daniel T. Corp ,&nbsp;Maria Concetta Altavista ,&nbsp;Vincenzo Di Lazzaro ,&nbsp;Massimo Marano","doi":"10.1016/j.clinph.2025.03.048","DOIUrl":"10.1016/j.clinph.2025.03.048","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to investigate the central effects of Botulinum toxin type A (BoNT-A) on the somatosensory system in patients with cervical dystonia (CD), focusing on the thalamocortical pathway using high-frequency oscillations (HFOs) and short-latency afferent inhibition (SAI).</div></div><div><h3>Methods</h3><div>An observational longitudinal study was conducted on 10CD patients and 10 healthy controls (HC). HFOs and SAI were assessed for CD and HC at baseline (T0; the day before BoNT-A treatment). Then only for CD patients, SAI and HFOs were assessed again 30 days after (T1) BoNT-A treatment. Changes in SAI values and HFO early and late area between T0 and T1 in CD patients were evaluated with the Wilcoxon signed-rank test.</div></div><div><h3>Results</h3><div>At T0, CD patients exhibited significantly reduced early HFOs compared to HC, with no significant differences in late HFOs or SAI values. After BoNT-A treatment, a significant increase in early HFOs was observed in CD patients at T1, while late HFOs and SAI values remained unchanged.</div></div><div><h3>Conclusion</h3><div>The findings suggest that BoNT-A treatment may have central effects on thalamocortical activity, as evidenced by changes of early HFOs in CD patients following injections.</div></div><div><h3>Significance</h3><div>This study provides neurophysiological evidence supporting the central effects of BoNT-A on the somatosensory system and corroborates the idea of a somatosensory involvement in CD pathogenesis. This funding could pave the way for future integrated treatment approaches.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2010733"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Instrument-supported gait analysis characterizes gait domain changes in patients with suspected normal pressure hydrocephalus 仪器支持的步态分析表征了疑似正常压力性脑积水患者的步态域变化
IF 3.6 3区 医学
Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110853
Carolin Semmler , Veronika Wunderle , Taylan Kuzu , Özgür A. Onur , Christian Grefkes-Hermann , Michael Barbe , Gereon R. Fink , Peter H. Weiß-Blankenhorn
{"title":"Instrument-supported gait analysis characterizes gait domain changes in patients with suspected normal pressure hydrocephalus","authors":"Carolin Semmler ,&nbsp;Veronika Wunderle ,&nbsp;Taylan Kuzu ,&nbsp;Özgür A. Onur ,&nbsp;Christian Grefkes-Hermann ,&nbsp;Michael Barbe ,&nbsp;Gereon R. Fink ,&nbsp;Peter H. Weiß-Blankenhorn","doi":"10.1016/j.clinph.2025.2110853","DOIUrl":"10.1016/j.clinph.2025.2110853","url":null,"abstract":"","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2110853"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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