Communications Chemistry最新文献

London dispersion forces and steric effects within nanocomposites tune interaction energies and chain conformation.

IF 5.9 2区化学

Communications Chemistry Pub Date : 2025-01-26 DOI: 10.1038/s42004-025-01414-4

Baode Zhang, Snežana D Zarić, Sonja S Zrilić, Iosif Gofman, Barbara Heck, Günter Reiter

引用次数: 0

Design of asymmetric electrolytes for aqueous zinc batteries.

IF 5.9 2区化学

Communications Chemistry Pub Date : 2025-01-24 DOI: 10.1038/s42004-024-01405-x

Shengmei Chen, Chunyi Zhi

{"title":"Design of asymmetric electrolytes for aqueous zinc batteries.","authors":"Shengmei Chen, Chunyi Zhi","doi":"10.1038/s42004-024-01405-x","DOIUrl":"10.1038/s42004-024-01405-x","url":null,"abstract":"Aqueous Zn batteries are gaining increasing research attention in the energy storage area due to their intrinsic safety, potentially low cost and environmental friendliness; however, the zinc dendrite formation, zinc corrosion, passivation and the hydrogen evolution reaction induced by water at the anode side, and materials dissolution as well as intrinsic poor reaction kinetics at cathode side in aqueous systems, seriously shorten the cycling life and decrease energy density of batteries and greatly hinder their development. Recent advancements in asymmetric electrolytes with various functions are promising to overcome such challenges for zinc batteries at the same time. It has been proved that the applications of asymmetric electrolytes show significant contributions in the field of zinc-based batteries in suppressing side reactions while maintaining electrochemical performance to satisfy both anode and cathode. Therefore, this perspective summarizes recent advancements in asymmetric electrolytes' design and applications for zinc batteries and outlines opportunities and future challenges, expecting continued research attention in this area.","PeriodicalId":10529,"journal":{"name":"Communications Chemistry","volume":"8 1","pages":"20"},"PeriodicalIF":5.9,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143037407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analytical protocol for measuring micro-molar quantities of sulfur volatile species in experimental high pressure and temperature fluids.

IF 5.9 2区化学

Communications Chemistry Pub Date : 2025-01-23 DOI: 10.1038/s42004-024-01370-5

Arianna Secchiari, Luca Toffolo, Sandro Recchia, Simone Tumiati

{"title":"Analytical protocol for measuring micro-molar quantities of sulfur volatile species in experimental high pressure and temperature fluids.","authors":"Arianna Secchiari, Luca Toffolo, Sandro Recchia, Simone Tumiati","doi":"10.1038/s42004-024-01370-5","DOIUrl":"10.1038/s42004-024-01370-5","url":null,"abstract":"Validating thermodynamic models is essential in experimental geosciences for exploring increasingly complex systems and developing analytical protocols. However, investigating solid-fluid equilibria in mm3-sized experimental capsules poses several challenges, particularly in sulfur-bearing chemical systems. These include maintaining bulk fluid composition and performing quantitative analysis with extremely low amounts of synthesized fluid. We present an innovative methodology for measuring ultra-low amounts of sulfur volatiles (H2S and SO2) generated during experimental runs at high pressure and temperature conditions of 3 GPa and 700 °C. Using solid sulfides (FeS + FeS2) and water as reactants, we performed redox-controlled syntheses employing a piston cylinder apparatus. We demonstrate that ex-situ measurements of these fluids by quadrupole mass spectrometry ensure accurate and precise analysis, confirming predicted thermodynamic compositions. This methodology allows in-depht investigation of sulfide solid-fluid equilibria, shedding light on sulfur volatiles behavior and geochemical cycles under high P-T conditions characteristic of the Earth's interior.","PeriodicalId":10529,"journal":{"name":"Communications Chemistry","volume":"8 1","pages":"19"},"PeriodicalIF":5.9,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and functional evaluation of a psoralen-conjugated nucleoside mimic for triplex-forming oligonucleotides.

IF 5.9 2区化学

Communications Chemistry Pub Date : 2025-01-22 DOI: 10.1038/s42004-025-01416-2

Yu Mikame, Haruki Toyama, Chikara Dohno, Takehiko Wada, Asako Yamayoshi

{"title":"Development and functional evaluation of a psoralen-conjugated nucleoside mimic for triplex-forming oligonucleotides.","authors":"Yu Mikame, Haruki Toyama, Chikara Dohno, Takehiko Wada, Asako Yamayoshi","doi":"10.1038/s42004-025-01416-2","DOIUrl":"10.1038/s42004-025-01416-2","url":null,"abstract":"Psoralen-conjugated triplex-forming oligonucleotides (Ps-TFOs) have been employed for the photodynamic regulation of gene expression by the photo-cross-linking of psoralen with the target DNA. However, stable triplex formation requires a consecutive purine base sequence in one strand of the target DNA duplexes. The pyrimidine-base interruption in the consecutive purine base sequence drastically decreases the thermodynamic stability of the corresponding triplex, which hampers the TFO application. Here, we propose a design of the Ps-TFO for stable triplex formation with target DNA sequences containing pyrimidine-base interruptions under physiological conditions. This Ps-TFO, named 1'(one)-psoralen-conjugated triplex-forming oligonucleotide (OPTO), incorporates a synthesized nucleoside mimic 1'-psoralen-conjugated deoxyribose to increase the thermodynamic stability of the corresponding triplex by the intercalation of psoralen. The triplex-forming abilities of the OPTO were successfully demonstrated in combination with LNA and 5-methylcytosine, indicating that the use of OPTO will expand the range of the target sequences of TFO for photodynamic gene regulation.","PeriodicalId":10529,"journal":{"name":"Communications Chemistry","volume":"8 1","pages":"18"},"PeriodicalIF":5.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineering of acyl ligase domain in non-ribosomal peptide synthetases to change fatty acid moieties of lipopeptides. 非核糖体肽合成酶中酰基连接酶结构域的工程改造以改变脂肽的脂肪酸部分。

IF 5.9 2区化学

Communications Chemistry Pub Date : 2025-01-21 DOI: 10.1038/s42004-024-01379-w

Rina Aoki, Eri Kumagawa, Kazuaki Kamata, Hideo Ago, Naoki Sakai, Tomohisa Hasunuma, Naoaki Taoka, Yukari Ohta, Shingo Kobayashi

引用次数: 0

Spatiotemporal control of translation in live zebrafish embryos via photoprotected mRNAs. 通过光保护mrna对活斑马鱼胚胎翻译的时空控制。

IF 5.9 2区化学

Communications Chemistry Pub Date : 2025-01-19 DOI: 10.1038/s42004-025-01411-7

Florian P Weissenboeck, Melissa Pieper, Helena Schepers, Sophie Hötte, Nils Klöcker, Sabine Hüwel, Andreas van Impel, Stefan Schulte-Merker, Andrea Rentmeister

{"title":"Spatiotemporal control of translation in live zebrafish embryos via photoprotected mRNAs.","authors":"Florian P Weissenboeck, Melissa Pieper, Helena Schepers, Sophie Hötte, Nils Klöcker, Sabine Hüwel, Andreas van Impel, Stefan Schulte-Merker, Andrea Rentmeister","doi":"10.1038/s42004-025-01411-7","DOIUrl":"10.1038/s42004-025-01411-7","url":null,"abstract":"Translation of mRNA into protein is a fundamental process and tightly controlled during development. Several mechanisms acting on the mRNA level regulate when and where an mRNA is expressed. To explore the effects of conditional and transient gene expression in a developing organism, it is vital to experimentally enable abrogation and restoration of translation. We recently developed the FlashCaps technology allowing preparation of translationally muted mRNAs and their controlled activation by light. Here, we validate its functionality in vivo. We demonstrate that translation of FlashCap-eGFP-mRNA can be triggered in zebrafish embryos with spatiotemporal control. The injected FlashCap-mRNA is stable for hours and remains muted. Light-mediated activation up to 24 h post fertilization produces visible amounts of eGFP and can be restricted to distinct parts of the embryo. This methodology extends the toolbox for vertebrate models by enabling researchers to locally activate mRNA translation at different timepoints during development.","PeriodicalId":10529,"journal":{"name":"Communications Chemistry","volume":"8 1","pages":"16"},"PeriodicalIF":5.9,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unlocking the potential of azide-phosphine Staudinger reaction for the synthesis of poly(arylene iminophosphorane)s and materials therefrom. 释放叠氮-膦Staudinger反应合成聚芳基亚磷烷及其材料的潜力。

IF 5.9 2区化学

Communications Chemistry Pub Date : 2025-01-16 DOI: 10.1038/s42004-024-01362-5

Tomaž Kotnik, Antoine Debuigne, Julien De Winter, Matej Huš, Albin Pintar, Sebastijan Kovačič

{"title":"Unlocking the potential of azide-phosphine Staudinger reaction for the synthesis of poly(arylene iminophosphorane)s and materials therefrom.","authors":"Tomaž Kotnik, Antoine Debuigne, Julien De Winter, Matej Huš, Albin Pintar, Sebastijan Kovačič","doi":"10.1038/s42004-024-01362-5","DOIUrl":"10.1038/s42004-024-01362-5","url":null,"abstract":"Iminophosphoranes with the general formula (R3P═NR') have great potential in synthetic chemistry as valuable precursors/intermediates in organic synthesis or as building blocks for various organic compounds. However, the synthetic approaches and conditions to prepare iminophosphoranes are still poorly understood, limiting the utility of this chemistry for organic materials. In this article, a simple and efficient synthesis of previously unattainable poly(arylene iminophosphoranes) is reported. The azide-phosphine Staudinger polycondensation is used, and the reaction conditions are carefully studied, including consideration of light and air, the influence of solvent and temperature, and investigation of the electronic and steric effects of multiazides. The newly defined reaction conditions appear to be highly versatile, allowing the use of both electron-rich and electron-deficient arylazides for reaction with phosphines to synthesize a library of poly(arylene iminophosphorane) networks that exhibit exceptional thermal and oxidative stability. Interestingly, despite the ylidic-form of the iminophosphorane linkage as shown by theoretical calculations, these newly developed poly(arylene-iminophosphorane) networks exhibit semiconducting properties, such as absorption band edges up to 800 nm and optical band gaps in the range of 1.70 to 2.40 eV. Finally, we demonstrate the broad applicability of these polymers by processing them into glassy films, creating foam-like structures and synthesizing metallo-polymer hybrids.","PeriodicalId":10529,"journal":{"name":"Communications Chemistry","volume":"8 1","pages":"15"},"PeriodicalIF":5.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11739626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discovery of bicyclic borane molecule B₁₄H₂₆. 双环硼烷分子B14H26的发现。

IF 5.9 2区化学

Communications Chemistry Pub Date : 2025-01-16 DOI: 10.1038/s42004-025-01409-1

Xiaoni Zhang, Tomoko Fujino, Yasunobu Ando, Yuki Tsujikawa, Tianle Wang, Takeru Nakashima, Haruto Sakurai, Kazuki Yamaguchi, Masafumi Horio, Hatsumi Mori, Jun Yoshinobu, Takahiro Kondo, Iwao Matsuda

{"title":"Discovery of bicyclic borane molecule B14H26.","authors":"Xiaoni Zhang, Tomoko Fujino, Yasunobu Ando, Yuki Tsujikawa, Tianle Wang, Takeru Nakashima, Haruto Sakurai, Kazuki Yamaguchi, Masafumi Horio, Hatsumi Mori, Jun Yoshinobu, Takahiro Kondo, Iwao Matsuda","doi":"10.1038/s42004-025-01409-1","DOIUrl":"10.1038/s42004-025-01409-1","url":null,"abstract":"The discovery of fullerene following the synthesis of graphene marked a paradigm shift in chemistry. Here, we report the discovery of biycycloborane, arising from the synthesis of borophane (hydrogen boride). Uniquely, this synthesis method involves a decomposition mechanism rather than traditional atom-by-atom assembly, marking an unique approach to constructing complex borane structures. The mass spectrometry unveiled that the stable molecule has a mass of 178 in atomic mass unit with a stoichiometry of B14H26. Optical spectra and simulations further evidenced its bicyclic structure, featuring fulvene-like heptagons or octagons. This borane molecule, analogous to cyclic hydrocarbons, adopts a unit configuration with a three-center two-electron (3c-2e) bonding, akin to diborane. The B14H26 molecule has been historically anticipated as a distant descendant of the dodecahedron borane, but it was born from the hydrogen boride sheet with a non-symmorphic symmetry. The discovery of biycycloborane expands the frontiers of boron chemistry, promising advancements in boron-based nanomaterials and beyond.","PeriodicalId":10529,"journal":{"name":"Communications Chemistry","volume":"8 1","pages":"14"},"PeriodicalIF":5.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11739403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deciphering the safeguarding role of cysteine residues in p53 against H₂O₂-induced oxidation using high-resolution native mass spectrometry. 利用高分辨率天然质谱法破译p53中半胱氨酸残基对h2o2诱导氧化的保护作用。

IF 5.9 2区化学

Communications Chemistry Pub Date : 2025-01-15 DOI: 10.1038/s42004-024-01395-w

Manuel David Peris-Díaz, Artur Krężel, Perdita Barran

引用次数: 0

Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation. 通过化学蛋白质组学筛选和高通量优化发现对映体选择性OTUD7B片段。

IF 5.9 2区化学

Communications Chemistry Pub Date : 2025-01-15 DOI: 10.1038/s42004-025-01410-8

Aini Vuorinen, Cassandra R Kennedy, Katherine A McPhie, William McCarthy, Jonathan Pettinger, J Mark Skehel, David House, Jacob T Bush, Katrin Rittinger

引用次数: 0