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Response to: Letter to the editor: Sleep measures and cardiovascular disease in type 2 diabetes mellitus. 回应致编辑的信：2型糖尿病患者的睡眠质量与心血管疾病。
IF 4.4 4区 医学
Clinical Medicine Pub Date : 2024-01-01 Epub Date: 2024-02-07 DOI: 10.1016/j.clinme.2024.100023
Caroline J Magri, Sara Xuereb, Rachel-Anne Xuereb, Robert G Xuereb, Stephen Fava, Joseph Galea
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引用次数: 0
Chronic pulmonary aspergillosis - a guide for the general physician. 慢性肺曲霉菌病--全科医生指南》。
IF 4.4 4区 医学
Clinical Medicine Pub Date : 2024-01-01 Epub Date: 2024-01-26 DOI: 10.1016/j.clinme.2024.100019
Charlotte Carter, Rasleen Kahai, Josie Cunningham, Jennifer Kilduff, Natasha Hough, Caroline Baxter, David Connell, Anand Shah
{"title":"Chronic pulmonary aspergillosis - a guide for the general physician.","authors":"Charlotte Carter, Rasleen Kahai, Josie Cunningham, Jennifer Kilduff, Natasha Hough, Caroline Baxter, David Connell, Anand Shah","doi":"10.1016/j.clinme.2024.100019","DOIUrl":"10.1016/j.clinme.2024.100019","url":null,"abstract":"<p><p>This collaborative article presents a review of chronic pulmonary aspergillosis (CPA) from the perspective of a multidisciplinary team comprising of respiratory physicians, radiologists, mycologists, dietitians, pharmacists, physiotherapists and palliative care specialists. The review synthesises current knowledge on CPA, emphasising the intricate interplay between clinical, radiological, and microbiological aspects. We highlight the importance of assessing each patient as multidisciplinary team to ensure personalised treatment strategies and a holistic approach to patient care.</p>","PeriodicalId":10492,"journal":{"name":"Clinical Medicine","volume":" ","pages":"100019"},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11024841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139569889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor: Are we missing pancreatic exocrine insufficiency in 'at-risk' groups? 致编辑的信：我们是否遗漏了 "高危 "人群中的胰腺外分泌功能不全？
IF 4.4 4区 医学
Clinical Medicine Pub Date : 2024-01-01 Epub Date: 2024-01-28 DOI: 10.1016/j.clinme.2024.100022
Moses Silungwe Kapembwa, Simon Charles Fleming, Philip Anthony Batman, George Edward Griffin
{"title":"Letter to the editor: Are we missing pancreatic exocrine insufficiency in 'at-risk' groups?","authors":"Moses Silungwe Kapembwa, Simon Charles Fleming, Philip Anthony Batman, George Edward Griffin","doi":"10.1016/j.clinme.2024.100022","DOIUrl":"10.1016/j.clinme.2024.100022","url":null,"abstract":"","PeriodicalId":10492,"journal":{"name":"Clinical Medicine","volume":" ","pages":"100022"},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11024837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139641762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The UK research ethics committee: Making the case for better serving the underserved - can we do better? 英国研究伦理委员会：为更好地服务于得不到充分服务的人群创造条件--我们能做得更好吗？
IF 4.4 4区 医学
Clinical Medicine Pub Date : 2024-01-01 Epub Date: 2024-02-12 DOI: 10.1016/j.clinme.2023.100012
Matthew Parsons, James Ratcliff, Bernadette Egan, Hana Hassanin, Aftab Ala
{"title":"The UK research ethics committee: Making the case for better serving the underserved - can we do better?","authors":"Matthew Parsons, James Ratcliff, Bernadette Egan, Hana Hassanin, Aftab Ala","doi":"10.1016/j.clinme.2023.100012","DOIUrl":"10.1016/j.clinme.2023.100012","url":null,"abstract":"<p><p>Research ethics committees exist internationally to review research proposals to protect the rights and safety of human participants and researchers involved in research. These committees recruit a panel of expert and lay members, mostly on an unpaid voluntary basis, with relevant scientific experience to appraise these studies. Contemporary data in the UK show that women and people over 55 years old are overrepresented in these committee panels in the Health Research Authority, suggesting that there are potential barriers to inclusivity and participation. A variety of global approaches to tackle these barriers include targeting specific populations, such as faith or community leaders, or implementing quotas have been adopted. Further research is needed to understand likely barriers preventing participation in research ethics committees in the UK and how they may be overcome.</p>","PeriodicalId":10492,"journal":{"name":"Clinical Medicine","volume":"24 1","pages":"100012"},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11024827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139729176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evidence-based appraisal of situational judgement tests (revisited). 致编辑的信：基于证据的情境判断测试评估（重温）。
IF 4.4 4区 医学
Clinical Medicine Pub Date : 2024-01-01 Epub Date: 2024-01-28 DOI: 10.1016/j.clinme.2024.100020
Gurvinder Sahota, John McLachlan, Fiona Patterson, Paul Tiffin
{"title":"Evidence-based appraisal of situational judgement tests (revisited).","authors":"Gurvinder Sahota, John McLachlan, Fiona Patterson, Paul Tiffin","doi":"10.1016/j.clinme.2024.100020","DOIUrl":"10.1016/j.clinme.2024.100020","url":null,"abstract":"","PeriodicalId":10492,"journal":{"name":"Clinical Medicine","volume":" ","pages":"100020"},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11024836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139641763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A complex case of dysphagia with dual aetiology. 一个具有双重病因的复杂吞咽困难病例。
IF 4.4 4区 医学
Clinical Medicine Pub Date : 2024-01-01 Epub Date: 2024-02-14 DOI: 10.1016/j.clinme.2023.100010
Catherine Sykes, Matthew Banks, Humayra Dervin, Andres Vales, Rami Sweis
{"title":"A complex case of dysphagia with dual aetiology.","authors":"Catherine Sykes, Matthew Banks, Humayra Dervin, Andres Vales, Rami Sweis","doi":"10.1016/j.clinme.2023.100010","DOIUrl":"10.1016/j.clinme.2023.100010","url":null,"abstract":"<p><p>A woman in her early 60s was referred with dysphagia and chest pain to a tertiary referral centre specialising in oesophageal disorders. Cardiac symptom origin and sinister oesophageal pathology had been excluded at her local hospital in NHS Scotland. Under multidisciplinary team oversight, reinvestigation of mucosal pathology and oesophageal motility ultimately uncovered both Type III achalasia and eosinophilic oesophagitis. This case demonstrates the benefit of including provocative testing during high-resolution manometry to reproduce relevant dysphagia and the importance of stopping proton-pump inhibitors long enough to uncover excessive eosinophils which could otherwise be masked. Ultimately, tailored management for both conditions separately was required to achieve symptoms resolution.</p>","PeriodicalId":10492,"journal":{"name":"Clinical Medicine","volume":"24 1","pages":"100010"},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11024826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139740528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep measures and cardiovascular disease in type 2 diabetes mellitus. 致编辑的信：2型糖尿病患者的睡眠质量与心血管疾病。
IF 4.4 4区 医学
Clinical Medicine Pub Date : 2024-01-01 Epub Date: 2024-01-28 DOI: 10.1016/j.clinme.2024.100021
M Engin
{"title":"Sleep measures and cardiovascular disease in type 2 diabetes mellitus.","authors":"M Engin","doi":"10.1016/j.clinme.2024.100021","DOIUrl":"10.1016/j.clinme.2024.100021","url":null,"abstract":"","PeriodicalId":10492,"journal":{"name":"Clinical Medicine","volume":" ","pages":"100021"},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11023003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139641764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patients with cancer and sepsis trials: an unfair representation? 癌症患者与败血症试验：不公平的代表性？
IF 4.4 4区 医学
Clinical Medicine Pub Date : 2023-12-08 DOI: 10.7861/clinmed.2023-0408
Elizabeth Nelmes, Luke Edwards, Shaman Jhanji, David B Antcliffe, Kate C Tatham
{"title":"Patients with cancer and sepsis trials: an unfair representation?","authors":"Elizabeth Nelmes, Luke Edwards, Shaman Jhanji, David B Antcliffe, Kate C Tatham","doi":"10.7861/clinmed.2023-0408","DOIUrl":"10.7861/clinmed.2023-0408","url":null,"abstract":"<p><p>Approximately 20% of sepsis cases are thought to occur in patients with cancer. Thus, such patients are an important cohort to be represented and characterised among sepsis trials. However, patients with cancer are commonly excluded from sepsis trials, although the extent to which is unknown. In this opinion article, we discuss our findings that suggest that patients with cancer are being under-represented in sepsis trials, often with an unclear rationale. We question the validity of generalising results from sepsis trials to heterogenous cancer populations and call for wider inclusion of patients with cancer to bridge this knowledge gap in sepsis management.</p>","PeriodicalId":10492,"journal":{"name":"Clinical Medicine","volume":" ","pages":"635-636"},"PeriodicalIF":4.4,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11046631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138486857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Time to treat the climate and nature crisis as one indivisible global health emergency. 是时候将气候和自然危机视为一个不可分割的全球卫生紧急事件了。
IF 4.4 4区 医学
Clinical Medicine Pub Date : 2023-12-08 DOI: 10.7861/clinmed.ed.23.6.2
Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski
{"title":"Time to treat the climate and nature crisis as one indivisible global health emergency.","authors":"Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski","doi":"10.7861/clinmed.ed.23.6.2","DOIUrl":"10.7861/clinmed.ed.23.6.2","url":null,"abstract":"","PeriodicalId":10492,"journal":{"name":"Clinical Medicine","volume":" ","pages":"643-645"},"PeriodicalIF":4.4,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54227970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research activity among physicians in the United Kingdom: results from the Royal College of Physicians Census 2022. 英国医生的研究活动：英国皇家内科学院 2022 年普查结果。
IF 4.4 4区 医学
Clinical Medicine Pub Date : 2023-12-08 DOI: 10.7861/clinmed.2023-0388
Subashini Chandrapalan, Chris Phillips, Nina Newbery, Sarah Logan, Ramesh Arasaradnam
{"title":"Research activity among physicians in the United Kingdom: results from the Royal College of Physicians Census 2022.","authors":"Subashini Chandrapalan, Chris Phillips, Nina Newbery, Sarah Logan, Ramesh Arasaradnam","doi":"10.7861/clinmed.2023-0388","DOIUrl":"10.7861/clinmed.2023-0388","url":null,"abstract":"<p><p>We present the results of the 2022 Census of the Federation of Royal Colleges of Physicians of Edinburgh, Glasgow and London on whether physicians undertake research and the barriers they have encountered. 40% of physicians reported that they undertook research alongside their clinical work. Multivariate analysis of the responses showed that men were 1.6 times more likely to say they undertake research than women. The main barriers to undertaking research were having enough time, organisational factors and a lack of confidence. In this opinion piece we discuss some of the challenges and how they could be addressed.</p>","PeriodicalId":10492,"journal":{"name":"Clinical Medicine","volume":" ","pages":"637-640"},"PeriodicalIF":4.4,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11046586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138486858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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