Colloid and Interface Science Communications最新文献

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Iron biomineralization by mediation of clMagR/clCry4 protein contribute to T2 contrast enhanced in MRI clMagR/clCry4蛋白介导的铁生物矿化有助于MRI增强T2对比
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2025-01-01 DOI: 10.1016/j.colcom.2024.100810
Nuan Li , Xiaofeng Han , Xiaoli Mai , Peng Wang , Fangxu Wang , Linyuan Wu , Yuanyuan Xie , Bin Wang
{"title":"Iron biomineralization by mediation of clMagR/clCry4 protein contribute to T2 contrast enhanced in MRI","authors":"Nuan Li ,&nbsp;Xiaofeng Han ,&nbsp;Xiaoli Mai ,&nbsp;Peng Wang ,&nbsp;Fangxu Wang ,&nbsp;Linyuan Wu ,&nbsp;Yuanyuan Xie ,&nbsp;Bin Wang","doi":"10.1016/j.colcom.2024.100810","DOIUrl":"10.1016/j.colcom.2024.100810","url":null,"abstract":"<div><div>Recent findings have sparked great interest in MagR/Cry4 protein that underpin animal magnetoreception. We tried to make progress in characterizing the <em>Columba livia</em> clMagR/clCry4, and connecting its properties to biological impacts. Throughout natural evolution, new functions of protein were never constructed from scratch, but from pre-existing parts. The clMagR/clCry4 was certainly not an exception. By employing synthetic biology, protein heterologous expression approach allowed protein function to be borrowed from nature to study their new traits. We introduced clMagR/clCry4 into the natural bacteria constructing the recombinant bacteria that perform biomineralization process. Our current work efforts were focused on investigating iron biomineralization in clMagR/clCry4 using electron microscopy. This is only one study, thus far, that describes clMagR/clCry4 deem as a likely candidate as iron biomineralization protein. Notably, iron biomineralization brings clMagR/clCry4 closer to its potential magnetoreception. Additionally, the obtained iron biominerals have shown a great promise to serve as <em>T</em><sub>2</sub> contrast agents for MRI application.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"64 ","pages":"Article 100810"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
BODIPY based nanomedicine for cancer imaging and phototherapy 基于BODIPY的纳米医学用于癌症成像和光疗
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2025-01-01 DOI: 10.1016/j.colcom.2024.100816
Dapeng Chen , Tian Zhang , Xiaochen Dong , Xiaozhou Mou
{"title":"BODIPY based nanomedicine for cancer imaging and phototherapy","authors":"Dapeng Chen ,&nbsp;Tian Zhang ,&nbsp;Xiaochen Dong ,&nbsp;Xiaozhou Mou","doi":"10.1016/j.colcom.2024.100816","DOIUrl":"10.1016/j.colcom.2024.100816","url":null,"abstract":"<div><div>Optical materials with imaging and phototherapy functionalities have offered promising perspectives for precise tumor treatment. Among these materials, boron-dipyrromethene (BODIPY) photosensitizers have presented potential for cancer theranostics because of their long wavelength absorption/fluorescence, tunable reactive oxygen species quantum yield, excellent photostability, and good biocompatibility. The development of nanotechnology in combination with BODIPY provided researchers with nanomedicines passively targeting solid tumors via enhanced penetration and retention effect, which greatly improved the efficacy of cancer photo-theranostics. In this review, we summarize our contributions for the development of BODIPY nanomedicine for cancer imaging and phototherapy. We firstly introduce our comprehensive routes for BODIPY synthesis and the preparation strategies of BODIPY nanomedicine. Thereafter, we give an in-depth discussion on the photo physicochemical properties of BODIPY nanomedicines, focusing on their applications in fluorescence/photothermal/photoacoustic imaging, photodynamic therapy, phototherapy, and combined phototherapy/vascular disruption therapy. Lastly, we look at the perspectives and challenges for the development of next-generation BODIPY nanomedicines.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"64 ","pages":"Article 100816"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insect cuticle: A source of inspiration for biomimetic Interface material design 昆虫角质层:仿生界面材料设计的灵感来源
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2025-01-01 DOI: 10.1016/j.colcom.2025.100818
Yang Zheng , Junwen Wang , Jianwen Wang , Yulong Li , Zhenqi Jiang
{"title":"Insect cuticle: A source of inspiration for biomimetic Interface material design","authors":"Yang Zheng ,&nbsp;Junwen Wang ,&nbsp;Jianwen Wang ,&nbsp;Yulong Li ,&nbsp;Zhenqi Jiang","doi":"10.1016/j.colcom.2025.100818","DOIUrl":"10.1016/j.colcom.2025.100818","url":null,"abstract":"<div><div>Insects represent one of the most ancient and diverse groups of organisms. Over 400 million years of evolution, their cuticles have evolved into highly optimized natural biomaterials that achieve a unique balance of lightweight structure, high strength, and elasticity. The remarkable properties of insect cuticles have inspired the development of biomimetic materials. In this review, we explore the structural organization, material properties, and key molecular components of insect cuticles, emphasizing their potential applications in both structural and molecular bionics. Special attention is given to areas such as protective coating, tissue engineering, and other biomaterials that demand exceptional elasticity or durability. Finally, we highlight future research directions on the molecular assembly mechanisms of insect cuticles, aiming to advance the design of high-performance, sustainable materials.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"64 ","pages":"Article 100818"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143097234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of nanoparticle concentration and magnetic fields to control the structures of superparamagnetic Fe3O4 nanoparticle Langmuir films 利用纳米颗粒浓度和磁场控制超顺磁性纳米Fe3O4朗缪尔薄膜的结构
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2025-01-01 DOI: 10.1016/j.colcom.2025.100817
Cathy E. McNamee , Daisuke Usui , Yuto Yamada , Hiroaki Shigekura , Shinpei Yamamoto
{"title":"Use of nanoparticle concentration and magnetic fields to control the structures of superparamagnetic Fe3O4 nanoparticle Langmuir films","authors":"Cathy E. McNamee ,&nbsp;Daisuke Usui ,&nbsp;Yuto Yamada ,&nbsp;Hiroaki Shigekura ,&nbsp;Shinpei Yamamoto","doi":"10.1016/j.colcom.2025.100817","DOIUrl":"10.1016/j.colcom.2025.100817","url":null,"abstract":"<div><div>We investigated how structures formed by hydrophobic superparamagnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles (NPs) at air-water interfaces could be changed, in order to achieve films with the desired structure. NP films were prepared on water using the Langmuir trough, and deposited onto glass substrates. The effect of the NP spreading solution concentration (<em>C</em><sub><em>NP</em></sub>) and the magnetic field strength on the NP aggregation were determined from surface pressure-area/particle isotherms and Atomic Force Microscope images. In the absence of a magnetic field, the NPs aggregated to form large and heterogeneous domains. The size and non-homogeneity of the domains increased as <em>C</em><sub><em>NP</em></sub> increased, a result explained by increasing attractive hydrophobic interactions. A magnetic field decreased the size and non-homogeneity of these domains, a result explained by a directional attractive magnetic force. The NP film structure depended on <em>C</em><sub><em>NP</em></sub> and the magnetic field strength. Structural changes by the magnetic field became more visible as <em>C</em><sub><em>NP</em></sub> was increased.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"64 ","pages":"Article 100817"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing lipid nanoparticles: A pioneering technology in cosmetic and dermatological treatments 推进脂质纳米颗粒:美容和皮肤治疗的先驱技术
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2025-01-01 DOI: 10.1016/j.colcom.2024.100814
Anil Pareek , Devesh U. Kapoor , Sandeep Kumar Yadav , Summya Rashid , Mohammad Fareed , Mohammad Suhail Akhter , Ghazala Muteeb , Madan Mohan Gupta , Bhupendra G. Prajapati
{"title":"Advancing lipid nanoparticles: A pioneering technology in cosmetic and dermatological treatments","authors":"Anil Pareek ,&nbsp;Devesh U. Kapoor ,&nbsp;Sandeep Kumar Yadav ,&nbsp;Summya Rashid ,&nbsp;Mohammad Fareed ,&nbsp;Mohammad Suhail Akhter ,&nbsp;Ghazala Muteeb ,&nbsp;Madan Mohan Gupta ,&nbsp;Bhupendra G. Prajapati","doi":"10.1016/j.colcom.2024.100814","DOIUrl":"10.1016/j.colcom.2024.100814","url":null,"abstract":"<div><div>Lipid nanoparticles (LNPs) represent a groundbreaking advancement in the realms of cosmetics and dermatology, providing advantages over traditional formulations. This paper explores the revolutionary potential of LNPs, particularly Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs), in enhancing cosmetic and dermatological applications. The review highlights the advantages of LNPs, including improved skin penetration, improved bioavailability and controlled release of active ingredients, which together contribute to their superior performance compared to conventional formulations. Notable applications discussed include their roles in acne treatment, anti-aging solutions, wound healing, skin-lightening products, and sunscreens. This study examines the structural features and formulation techniques of LNPs, highlighting biocompatibility, and targeted delivery capabilities. We also explore emerging uses such as genetic medicine and mRNA vaccine delivery, alongside market trends and consumer acceptance. By summarizing recent developments and identifying existing challenges, this paper offers a thorough overview of LNPs for future research in pharmaceutical and cosmetic advancements.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"64 ","pages":"Article 100814"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Construction of superficial pyrrolidone-rich polymer nanoparticles as integrated sustainable materials for iodine adsorption and bacteria eradication 表面富吡咯烷酮聚合物纳米颗粒作为碘吸附和除菌综合可持续材料的构建
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2025-01-01 DOI: 10.1016/j.colcom.2024.100812
Shi Lan , Mengnan Chu , Tingrui Yuan , Yanyang Duan , Shuang Zhao , Xianliang Sheng , Alideertu Dong
{"title":"Construction of superficial pyrrolidone-rich polymer nanoparticles as integrated sustainable materials for iodine adsorption and bacteria eradication","authors":"Shi Lan ,&nbsp;Mengnan Chu ,&nbsp;Tingrui Yuan ,&nbsp;Yanyang Duan ,&nbsp;Shuang Zhao ,&nbsp;Xianliang Sheng ,&nbsp;Alideertu Dong","doi":"10.1016/j.colcom.2024.100812","DOIUrl":"10.1016/j.colcom.2024.100812","url":null,"abstract":"<div><div>The past few decades have witnessed plenty of research activities in advanced adsorbents for iodine pollutant treatment, but little attention has been paid to the reutilization of them. Herein, we report on superficial pyrrolidone-rich polymer nanoparticles (<em>i.e.</em>, PMP NPs) as integrated sustainable materials for the effective removal of iodine from waste, coupled with their reutilization in antibacterial-associated areas. The pyrrolidone groups on the surface of PMP NPs served as adsorbing sites for capturing iodine and having the special capability of desorbing iodine in the presence of starch or bacteria. The as-captured iodine showed excellent <em>in vitro</em> antibacterial ability against 10<sup>7</sup> CFU·mL<sup>−1</sup> of <em>Escherichia coli</em> (<em>E. coli</em>) and <em>Staphylococcus aureus</em> (<em>S. aureus</em>). We believed that this “turning waste into treasure” strategy based on the synergism of iodine adsorption and antibacterial utilization should have great potential for environmental remediation and public healthcare.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"64 ","pages":"Article 100812"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143097235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-layer kagome lattices assembled with isotropic spherical colloids via heteroepitaxial growth 通过异质外延生长,由各向同性球形胶体组装而成的多层kagome晶格
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2025-01-01 DOI: 10.1016/j.colcom.2024.100815
Jun Nozawa , Masahide Sato , Satoshi Uda , Kozo Fujiwara
{"title":"Multi-layer kagome lattices assembled with isotropic spherical colloids via heteroepitaxial growth","authors":"Jun Nozawa ,&nbsp;Masahide Sato ,&nbsp;Satoshi Uda ,&nbsp;Kozo Fujiwara","doi":"10.1016/j.colcom.2024.100815","DOIUrl":"10.1016/j.colcom.2024.100815","url":null,"abstract":"<div><div>The control of structure is crucial for diverse applications of colloidal crystals. Open-structure colloidal crystals are promising in their novel optical or mechanical properties, yet fabrication remains a significant challenge. Here, we demonstrate fabrication of multi-layer colloidal kagome lattices via heteroepitaxial growth. Unlike previous methods that rely on anisotropic particles, such as Janus particles, our approach utilizes common isotropic spherical polystyrene particles. We fabricated multi-layered kagome lattices, in contrast to techniques that were limited to forming single layers. The first layer in the kagome lattice formation on a substrate was a multi-step process, as revealed by in situ-observations. Then repeated stacking of kagome lattice layers occurred stably. This heteroepitaxial growth technique offers a feasible approach to self-assemble open-structure colloidal crystals.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"64 ","pages":"Article 100815"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Honeycomb BiFeO3 catalysts harvest mechanical energy from ultrasonic vibrations for efficient piezoelectric-catalyzed degradation of antibiotics 蜂窝状BiFeO3催化剂从超声波振动中获取机械能,用于有效的压电催化抗生素降解
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2025-01-01 DOI: 10.1016/j.colcom.2024.100813
Jun Teng , Du Tao , Feng Li , Taohai Li
{"title":"Honeycomb BiFeO3 catalysts harvest mechanical energy from ultrasonic vibrations for efficient piezoelectric-catalyzed degradation of antibiotics","authors":"Jun Teng ,&nbsp;Du Tao ,&nbsp;Feng Li ,&nbsp;Taohai Li","doi":"10.1016/j.colcom.2024.100813","DOIUrl":"10.1016/j.colcom.2024.100813","url":null,"abstract":"<div><div>Piezocatalysis has attracted much attention for its efficient performance in removing pharmaceuticals and dyes from wastewater. In this work, the piezoelectric system was applied by environmental-benign BiFeO<sub>3</sub> catalysis for the removal of antibiotics in the water. The irregular honeycomb-like BiFeO<sub>3</sub> was prepared through a simple co-precipitation route with composite precipitants. The results demonstrated that BiFeO<sub>3</sub> exhibited excellent piezoelectric catalytic degradation performance for metronidazole under ultrasonic vibration. The effects of catalyst dosage, initial metronidazole concentration, solution pH, and ultrasonic power on piezoelectric catalytic efficiency were systematically investigated. It was found that the highest piezoelectric catalytic degradation efficiency of metronidazole was 98.87 %. The catalyst stability of the catalyst showed that it had excellent piezoelectric catalytic degradation Finally, the degradation efficiency of metronidazole was only reduced by 4 % through four cycles, which demonstrated the good stability and reusability of BiFeO<sub>3</sub>.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"64 ","pages":"Article 100813"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adhesion mechanisms and design strategies for bioadhesives 生物粘合剂的粘合机制和设计策略
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-11-01 DOI: 10.1016/j.colcom.2024.100809
Yihang Ding , Lisha Yu , Zhengwei Mao
{"title":"Adhesion mechanisms and design strategies for bioadhesives","authors":"Yihang Ding ,&nbsp;Lisha Yu ,&nbsp;Zhengwei Mao","doi":"10.1016/j.colcom.2024.100809","DOIUrl":"10.1016/j.colcom.2024.100809","url":null,"abstract":"<div><div>Bioadhesives are widely used in medical fields due to their compatibility with biological soft tissues and their ability to facilitate non-invasive wound closure. Despite their widespread clinical applications, the inadequate adhesion performance highlights the need for further refinement and innovation of these materials. A profound comprehension of the underlying mechanisms of tissue adhesion is essential for the successful development of bioadhesives. This review elucidates adhesion mechanisms and design principles for bioadhesives, emphasizing strategies to enhance interfacial adhesion and cohesion performance. We also provide a forward-looking perspective on the challenges and emerging trends for the development of next-generation bioadhesives. The progress of bioadhesives has significant potential to revolutionize wound management.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"63 ","pages":"Article 100809"},"PeriodicalIF":4.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spongosome-based co-delivery of curcumin and Piperine: A novel strategy for mitigating pollution-induced skin damage 以海绵为基础的姜黄素和胡椒碱的共同递送:减轻污染引起的皮肤损伤的新策略
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-11-01 DOI: 10.1016/j.colcom.2024.100811
Agnese Bondi , Francesca Ferrara , Walter Pula , Paolo Mariani , Alessia Pepe , Markus Drechsler , Leda Montesi , Stefano Manfredini , Giuseppe Valacchi , Elisabetta Esposito
{"title":"Spongosome-based co-delivery of curcumin and Piperine: A novel strategy for mitigating pollution-induced skin damage","authors":"Agnese Bondi ,&nbsp;Francesca Ferrara ,&nbsp;Walter Pula ,&nbsp;Paolo Mariani ,&nbsp;Alessia Pepe ,&nbsp;Markus Drechsler ,&nbsp;Leda Montesi ,&nbsp;Stefano Manfredini ,&nbsp;Giuseppe Valacchi ,&nbsp;Elisabetta Esposito","doi":"10.1016/j.colcom.2024.100811","DOIUrl":"10.1016/j.colcom.2024.100811","url":null,"abstract":"<div><div>The present study aims to explore the potential role of curcumin and piperine loaded spongosomes to protect the skin against pollution-induced damage. The hydration of a glyceryl monooleate and sodium cholate thin film, followed by homogenization, led to dispersions with an internal spongiform structure, as demonstrated by cryogenic transmission electron microscopy and small angle X-ray scattering. Spongosome mean diameter measured by photon correlation spectroscopy was roughly 200 nm. Curcumin and piperine were efficiently encapsulated in spongosomes, as demonstrated by ultrafiltration and HPLC analysis. In vitro permeation tests revealed that piperine enhances the penetration of curcumin, suggesting a further improved bioavailability and sustained release. Ex vivo studies using human skin biopsies showed that curcumin and piperine-loaded spongosomes protect the skin against diesel exhaust emissions, preserving the levels of key skin barrier proteins, as filaggrin and involucrin. The formulations exhibited non-irritating properties in human patch tests, supporting their suitability for topical application.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"63 ","pages":"Article 100811"},"PeriodicalIF":4.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142742888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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