Colloid and Interface Science Communications最新文献

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Adhesion mechanisms and design strategies for bioadhesives 生物粘合剂的粘合机制和设计策略
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-11-01 DOI: 10.1016/j.colcom.2024.100809
Yihang Ding , Lisha Yu , Zhengwei Mao
{"title":"Adhesion mechanisms and design strategies for bioadhesives","authors":"Yihang Ding ,&nbsp;Lisha Yu ,&nbsp;Zhengwei Mao","doi":"10.1016/j.colcom.2024.100809","DOIUrl":"10.1016/j.colcom.2024.100809","url":null,"abstract":"<div><div>Bioadhesives are widely used in medical fields due to their compatibility with biological soft tissues and their ability to facilitate non-invasive wound closure. Despite their widespread clinical applications, the inadequate adhesion performance highlights the need for further refinement and innovation of these materials. A profound comprehension of the underlying mechanisms of tissue adhesion is essential for the successful development of bioadhesives. This review elucidates adhesion mechanisms and design principles for bioadhesives, emphasizing strategies to enhance interfacial adhesion and cohesion performance. We also provide a forward-looking perspective on the challenges and emerging trends for the development of next-generation bioadhesives. The progress of bioadhesives has significant potential to revolutionize wound management.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"63 ","pages":"Article 100809"},"PeriodicalIF":4.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spongosome-based co-delivery of curcumin and Piperine: A novel strategy for mitigating pollution-induced skin damage
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-11-01 DOI: 10.1016/j.colcom.2024.100811
Agnese Bondi , Francesca Ferrara , Walter Pula , Paolo Mariani , Alessia Pepe , Markus Drechsler , Leda Montesi , Stefano Manfredini , Giuseppe Valacchi , Elisabetta Esposito
{"title":"Spongosome-based co-delivery of curcumin and Piperine: A novel strategy for mitigating pollution-induced skin damage","authors":"Agnese Bondi ,&nbsp;Francesca Ferrara ,&nbsp;Walter Pula ,&nbsp;Paolo Mariani ,&nbsp;Alessia Pepe ,&nbsp;Markus Drechsler ,&nbsp;Leda Montesi ,&nbsp;Stefano Manfredini ,&nbsp;Giuseppe Valacchi ,&nbsp;Elisabetta Esposito","doi":"10.1016/j.colcom.2024.100811","DOIUrl":"10.1016/j.colcom.2024.100811","url":null,"abstract":"<div><div>The present study aims to explore the potential role of curcumin and piperine loaded spongosomes to protect the skin against pollution-induced damage. The hydration of a glyceryl monooleate and sodium cholate thin film, followed by homogenization, led to dispersions with an internal spongiform structure, as demonstrated by cryogenic transmission electron microscopy and small angle X-ray scattering. Spongosome mean diameter measured by photon correlation spectroscopy was roughly 200 nm. Curcumin and piperine were efficiently encapsulated in spongosomes, as demonstrated by ultrafiltration and HPLC analysis. In vitro permeation tests revealed that piperine enhances the penetration of curcumin, suggesting a further improved bioavailability and sustained release. Ex vivo studies using human skin biopsies showed that curcumin and piperine-loaded spongosomes protect the skin against diesel exhaust emissions, preserving the levels of key skin barrier proteins, as filaggrin and involucrin. The formulations exhibited non-irritating properties in human patch tests, supporting their suitability for topical application.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"63 ","pages":"Article 100811"},"PeriodicalIF":4.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142742888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Icariin-loaded multilayered films deposited onto micro/nanostructured titanium enhances osteogenesis and reduces inflammation under diabetic conditions 沉积在微/纳米结构钛上的淫羊藿苷多层膜可促进骨生成并减轻糖尿病条件下的炎症反应
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-10-28 DOI: 10.1016/j.colcom.2024.100808
Xiaojing Zhang , Jia Chen , Junxiao Li , Weina Wang , Xi Chen , Xingtang Fang , Chunlei Zhang , Yanhua Hou , Min Lai
{"title":"Icariin-loaded multilayered films deposited onto micro/nanostructured titanium enhances osteogenesis and reduces inflammation under diabetic conditions","authors":"Xiaojing Zhang ,&nbsp;Jia Chen ,&nbsp;Junxiao Li ,&nbsp;Weina Wang ,&nbsp;Xi Chen ,&nbsp;Xingtang Fang ,&nbsp;Chunlei Zhang ,&nbsp;Yanhua Hou ,&nbsp;Min Lai","doi":"10.1016/j.colcom.2024.100808","DOIUrl":"10.1016/j.colcom.2024.100808","url":null,"abstract":"<div><div>Disordered bone metabolism and the associated inflammatory microenvironment in diabetic patients make treating bone fractures difficult in this patient population. However, the inherent bioinert properties of titanium implants result in insufficient osseointegration, making it important to develop an efficient surface modification strategy to provide titanium implants with enhanced osseointegration capabilities in diabetic conditions. Here, a micro/nanostructure was constructed on titanium through acid etching and anodic oxidation, followed by an addition of a multilayered film of chitosan (CHI), gelatin (GEL) and icariin (ICA) onto the surface of micro/nanostructured titanium using a layer-by-layer self-assembly technology. The characterization results indicated that the icariin-loaded multilayered film was successfully deposited onto titanium surface and achieved a long-term sustainable release of ICA. Cell experiments showed that the icariin-loaded multilayered films modified titanium promoted osteogenesis, inhibited osteoclast generation, and reduced inflammatory reaction under diabetic conditions. This study provides an avenue for treating fractures in patients with diabetes.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"63 ","pages":"Article 100808"},"PeriodicalIF":4.7,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From dairy waste to value-added bio-based surfactants 从乳制品废料到高附加值的生物基表面活性剂
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-09-21 DOI: 10.1016/j.colcom.2024.100807
Giorgia Ballabio , Sara Sangiorgio , Eleonora Pargoletti , Rita Gelli , Massimo Bonini , Marco Rabuffetti , Giuseppe Cappelletti , Giovanna Speranza
{"title":"From dairy waste to value-added bio-based surfactants","authors":"Giorgia Ballabio ,&nbsp;Sara Sangiorgio ,&nbsp;Eleonora Pargoletti ,&nbsp;Rita Gelli ,&nbsp;Massimo Bonini ,&nbsp;Marco Rabuffetti ,&nbsp;Giuseppe Cappelletti ,&nbsp;Giovanna Speranza","doi":"10.1016/j.colcom.2024.100807","DOIUrl":"10.1016/j.colcom.2024.100807","url":null,"abstract":"<div><div>Cheese whey permeate, the main waste stream of dairy industry, was used as a starting material for the production of bio-based surfactants (SFAEs). Specifically, the first step in the sustainable chemoenzymatic synthesis of <em>n</em>-butyl 6-<em>O</em>-palmitoyl-<span>D</span>-glycosides (Fischer glycosylation followed by enzymatic esterification) was optimized by a chemometric study. The surfactancy of the prepared isomeric mixtures was deeply investigated in terms of static and dynamic interfacial tension and emulsifying capability over time.</div></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"63 ","pages":"Article 100807"},"PeriodicalIF":4.7,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215038224000426/pdfft?md5=eec654311e93bf0c2e385beccb257318&pid=1-s2.0-S2215038224000426-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colloidal photonic crystals with tunable reflection wavelengths or intensities derived from their reconfigurable structures 具有可调反射波长或强度的可重构结构胶体光子晶体
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-09-01 DOI: 10.1016/j.colcom.2024.100806
Hikaru Namigata , Kanako Watanabe , Tom A.J. Welling , Keishi Suga , Daisuke Nagao
{"title":"Colloidal photonic crystals with tunable reflection wavelengths or intensities derived from their reconfigurable structures","authors":"Hikaru Namigata ,&nbsp;Kanako Watanabe ,&nbsp;Tom A.J. Welling ,&nbsp;Keishi Suga ,&nbsp;Daisuke Nagao","doi":"10.1016/j.colcom.2024.100806","DOIUrl":"10.1016/j.colcom.2024.100806","url":null,"abstract":"<div><p>Colloidal photonic crystals (CPCs), which are the ordered assemblies of colloidal particles, can reflect specific wavelengths of light. In particular, CPCs with controllable optical properties are promising materials for advanced photonic applications. Principally, the optical properties of CPCs, i.e., reflection wavelengths and reflection intensities, are controllable. These two characteristics are closely related to the assembled structures of CPCs, especially interplanar spacing and regularity of the assembled structures. The reflection wavelength is proportional to the interplanar spacing of the structure; thus, uniform expanding/contracting of particle-to-particle distance causes red/blue shift of reflection peaks. On the other hand, the regularity affects the reflection intensity; reversible order–disorder transitions enable tuning of the reflection peak intensities. To control the structures of CPCs, various stimuli-responsive polymers and electromagnetic interactions of colloids have been employed. This review explains the above methods and clarifies the future perspectives.</p></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"62 ","pages":"Article 100806"},"PeriodicalIF":4.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215038224000414/pdfft?md5=1a401ae7e9b68616a27dcb098314523e&pid=1-s2.0-S2215038224000414-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142148643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gold nanoparticles antibacterial activity: Does the surface matter? 金纳米粒子的抗菌活性:表面重要吗?
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-09-01 DOI: 10.1016/j.colcom.2024.100804
Marwan Saed, Raphael D. Ayivi, Jianjun Wei, Sherine O. Obare
{"title":"Gold nanoparticles antibacterial activity: Does the surface matter?","authors":"Marwan Saed,&nbsp;Raphael D. Ayivi,&nbsp;Jianjun Wei,&nbsp;Sherine O. Obare","doi":"10.1016/j.colcom.2024.100804","DOIUrl":"10.1016/j.colcom.2024.100804","url":null,"abstract":"<div><p>The misuse and overuse of antibiotics have ushered in the rapid rise of antimicrobial resistance (AMR). Gold nanoparticles (AuNPs) are considered a potential solution for AMR due to their dual role as antibacterial agents and antibiotic-delivery vehicles. AuNPs with varied surface area, charge, and morphology have been utilized alone and with antibiotics tailored on their surface to overcome resistant bacteria. However, transitioning AuNPs from lab to bedside faces challenges due to the inconsistent antibacterial outcomes and the need for a consensus on the optimal AuNP features that harness their potential as antibacterial agents. This review navigates through the interplay of AuNPs' surface and their antibacterial behavior, considering their surface charge, surface potential, surface coating, surface area, morphology, and antibiotic functionalization. Our review serves as a guide for AuNPs surface features that elicit the most favorable antibacterial outcomes, which will aid in formulating a novel antibacterial agent capable of counteracting AMR.</p></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"62 ","pages":"Article 100804"},"PeriodicalIF":4.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215038224000396/pdfft?md5=d9e712ecde12e50bba21f06c886a9b7a&pid=1-s2.0-S2215038224000396-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142148688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unraveling the stress-induced toxicity of black phosphorus nanosheets and the underlying mechanism 揭示黑磷纳米片的应力诱导毒性及其内在机理
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-09-01 DOI: 10.1016/j.colcom.2024.100802
Zhenlin Fan , Shunjie Wu , Ziheng An , Yiyang Wang , Bohan Xu , Xiaotong Wang , Yihua Xu , He Li , Guangxin Duan , Shitong Zhang , Xin Tian
{"title":"Unraveling the stress-induced toxicity of black phosphorus nanosheets and the underlying mechanism","authors":"Zhenlin Fan ,&nbsp;Shunjie Wu ,&nbsp;Ziheng An ,&nbsp;Yiyang Wang ,&nbsp;Bohan Xu ,&nbsp;Xiaotong Wang ,&nbsp;Yihua Xu ,&nbsp;He Li ,&nbsp;Guangxin Duan ,&nbsp;Shitong Zhang ,&nbsp;Xin Tian","doi":"10.1016/j.colcom.2024.100802","DOIUrl":"10.1016/j.colcom.2024.100802","url":null,"abstract":"<div><p>The unique physicochemical properties of black phosphorus (BP) nanomaterials make them extremely versatile, and growing concern has emerged regarding their biocompatibility. Here, we investigate the toxic profile of BP nanosheets under oxidative stress conditions in living cells and a simple animal model, <em>Caenorhabditis elegans</em>. Under normal conditions, BP nanosheets exhibit no adverse effects on cells and worms. However, the ability of cells and worms to resist oxidative stress is significantly impaired by BP nanosheets. Mechanism studies show that hydroxyl radical overproduction is induced by the reaction between BP nanosheets and H<sub>2</sub>O<sub>2</sub>, which may disrupt mitochondrial integrity and promote the leakage of cytochrome <em>c</em> from mitochondria into cytoplasm. Meanwhile, BP nanosheets are degraded under oxidative stress conditions, providing opportunities for BP nanosheets to interact with cytochrome <em>c</em>, thereby disrupting the cellular antioxidant defense system and ultimately producing toxicity. Our research uncovers the potential mechanism of BP nanosheets with oxidative stress-induced toxicity.</p></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"62 ","pages":"Article 100802"},"PeriodicalIF":4.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215038224000372/pdfft?md5=82f969790541e80b697370db402b6b9e&pid=1-s2.0-S2215038224000372-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142148691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Influence of the chemically reduced graphene oxide interface on the antioxidant multienzyme properties of Prussian blue nanoparticles” [Colloid and Interface Science Communications 52 (2023) 100689] 化学还原氧化石墨烯界面对普鲁士蓝纳米颗粒抗氧化多酶特性的影响》[《胶体与界面科学通讯》52 (2023) 100689]更正
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-09-01 DOI: 10.1016/j.colcom.2024.100805
Yunong Zhang , Liubov Pershina , David Kudriashov , Andreas Offenhäusser , Yulia Mourzina
{"title":"Corrigendum to “Influence of the chemically reduced graphene oxide interface on the antioxidant multienzyme properties of Prussian blue nanoparticles” [Colloid and Interface Science Communications 52 (2023) 100689]","authors":"Yunong Zhang ,&nbsp;Liubov Pershina ,&nbsp;David Kudriashov ,&nbsp;Andreas Offenhäusser ,&nbsp;Yulia Mourzina","doi":"10.1016/j.colcom.2024.100805","DOIUrl":"10.1016/j.colcom.2024.100805","url":null,"abstract":"","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"62 ","pages":"Article 100805"},"PeriodicalIF":4.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215038224000402/pdfft?md5=f4933453da549678c39e0c798640ac23&pid=1-s2.0-S2215038224000402-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142244168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced anticancer activity of N,N-bis(5-ethyl-2-hydroxybenzyl)methylamine (EMD) hydrophobic drug encapsulated in β-cyclodextrin nanosponges 增强包裹在β-环糊精纳米海绵中的 N,N-双(5-乙基-2-羟基苄基)甲胺(EMD)疏水性药物的抗癌活性
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-09-01 DOI: 10.1016/j.colcom.2024.100803
Sunisa Thongsom , Paolo Di Gianvincenzo , Suchittra Konkankun , Agustín Blachman , Silvestre Bongiovanni Abel , Natcha Madared , Chanchai Boonla , Pithi Chanvorachote , Sergio E. Moya
{"title":"Enhanced anticancer activity of N,N-bis(5-ethyl-2-hydroxybenzyl)methylamine (EMD) hydrophobic drug encapsulated in β-cyclodextrin nanosponges","authors":"Sunisa Thongsom ,&nbsp;Paolo Di Gianvincenzo ,&nbsp;Suchittra Konkankun ,&nbsp;Agustín Blachman ,&nbsp;Silvestre Bongiovanni Abel ,&nbsp;Natcha Madared ,&nbsp;Chanchai Boonla ,&nbsp;Pithi Chanvorachote ,&nbsp;Sergio E. Moya","doi":"10.1016/j.colcom.2024.100803","DOIUrl":"10.1016/j.colcom.2024.100803","url":null,"abstract":"<div><p><em>N, N-</em>bis (5-ethyl-2-hydroxybenzyl) methylamine (EMD) is a synthetic benzoxazine dimer compound. EMD targets and degrades the pro-oncogenic transcription factor c-Myc, initiating apoptosis in cancer cells. However, its use is restricted because of poor aqueous solubility and in physiological media. Cyclodextrin nanosponges (CN), a type of supramolecular macrocyclic polymer nanoparticles with hydrophobic cavities but soluble in water, are utilized here to load EMD in order to enhance its solubility. CNs with three different molar ratios of β-cyclodextrin (βCD)-to-citric acid crosslinker are synthesized: CN1 (βCD/citric acid 1:3), CN2 (βCD/citric acid 1:5), and CN3 (βCD/citric acid 1:8), and then loaded with EMD. EMD-CN2 exhibits a significantly higher solubilization efficiency (579.1 μg/mL) compared to the free EMD (59.09 μg/mL). The increased aqueous solubility of CN encapsulated EMD enhanced its anti-cancer efficacy. In vitro cytotoxicity, colony formation inhibition, and c-Myc suppression of EMD in cancer cells (A549 and HCT116) <em>are</em> improved over free EMD administration.</p></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"62 ","pages":"Article 100803"},"PeriodicalIF":4.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215038224000384/pdfft?md5=e86ae260a8588682692db3551f969899&pid=1-s2.0-S2215038224000384-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142148692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabrication of micro-porous polymeric coating with dynamic drug-eluting property on plastic biliary stent for antiproliferative treatment 在塑料胆道支架上制作具有动态药物洗脱特性的微孔聚合物涂层,用于抗增生治疗
IF 4.7 3区 材料科学
Colloid and Interface Science Communications Pub Date : 2024-08-27 DOI: 10.1016/j.colcom.2024.100801
Baozhang Shi , Hao Wei , Hongyue Miu , Liangliang Li , Jianing Zhu , Yubing Huo , Liping Xu , Wei Sun
{"title":"Fabrication of micro-porous polymeric coating with dynamic drug-eluting property on plastic biliary stent for antiproliferative treatment","authors":"Baozhang Shi ,&nbsp;Hao Wei ,&nbsp;Hongyue Miu ,&nbsp;Liangliang Li ,&nbsp;Jianing Zhu ,&nbsp;Yubing Huo ,&nbsp;Liping Xu ,&nbsp;Wei Sun","doi":"10.1016/j.colcom.2024.100801","DOIUrl":"10.1016/j.colcom.2024.100801","url":null,"abstract":"<div><p>The current study aims to construct additional drug-eluting carrier for commercially available biliary stent, providing a practical strategy for the cost-efficient treatment of benign biliary stricture. Specifically, the commercially available biliary stent was endowed with porous polylactic acid coating <em>via in-situ</em> pore-formation induced by solvent treatment. The drug-eluting stent with fibroblast inhibition effect was successfully established by efficiently loading the antiproliferative drug of triamcinolone acetonide into the porous coating. The drug release behavior could be dynamically controlled by adjusting the pore morphology of the porous coating. The <em>in-vitro</em> coating degradation and the fibroblast inhibition effect of the drug-eluting stents were further evaluated to prove the effectiveness of the fabricated porous coating as an antiproliferative drug carrier.</p></div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"62 ","pages":"Article 100801"},"PeriodicalIF":4.7,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215038224000360/pdfft?md5=86a5a25e7dac12c0d628a8181babf102&pid=1-s2.0-S2215038224000360-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142078055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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