Colloid and Interface Science Communications最新文献_第10页

Hybrid organosilica nanoagent with Fenton-like reaction activity and glutathione depletion for augmented chemo/chemodynamic therapy 具有芬顿样反应活性和谷胱甘肽耗竭的杂化有机二氧化硅纳米剂用于增强化疗/化疗动力学治疗

IF 4.5 3区材料科学

Colloid and Interface Science Communications Pub Date : 2023-09-01 DOI: 10.1016/j.colcom.2023.100739

Jia Ren , Xiaorui Jiao , Mahmood Hassan Akhtar , Muhammad Azhar Hayat Nawaz , Na Yang , Chang Liu , Xin Wen , Ying Li , Ning Liu , Cong Yu

{"title":"Hybrid organosilica nanoagent with Fenton-like reaction activity and glutathione depletion for augmented chemo/chemodynamic therapy","authors":"Jia Ren , Xiaorui Jiao , Mahmood Hassan Akhtar , Muhammad Azhar Hayat Nawaz , Na Yang , Chang Liu , Xin Wen , Ying Li , Ning Liu , Cong Yu","doi":"10.1016/j.colcom.2023.100739","DOIUrl":"https://doi.org/10.1016/j.colcom.2023.100739","url":null,"abstract":"<div>Development of efficient and specialized anti-cancer agent is highly desirable for both basic and clinical research. Herein, a multifunctional organosilica nanoagent (MOCL-DOX) loaded with copper ion, arginine, and doxorubicin was designed and prepared. Copper ion (Cu2+) and arginine (LA) were doped into the S-S bond-containing degradable organosilica nanocarrier as functional components. S-S bonds were broken under excessive glutathione (GSH) conditions when the nanoagent reached the tumor sites. Simultaneously Cu2+ was released, reduced by GSH to Cu+, and Cu+ selectively converted hydrogen peroxide (H2O2) to hydroxyl radical (•OH) by Fenton-like reaction which caused extensive cellular oxidation and even apoptosis. Tumor cell viability and growth were inhibited to a great extent by the combination of CDT and chemotherapy with minimal normal cells toxicity. Thus, the MOCL-DOX nanoagent demonstrates as a novel paradigm for the fabrication of Fenton's nanoagent for efficient cancer therapy with minimal side effects.</div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"56 ","pages":"Article 100739"},"PeriodicalIF":4.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49710144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hexagonal boron nitride nanodots inhibit cell proliferation of HUVECs and the underlying mechanism 六方氮化硼纳米点抑制HUVECs细胞增殖及其机制

IF 4.5 3区材料科学

Colloid and Interface Science Communications Pub Date : 2023-09-01 DOI: 10.1016/j.colcom.2023.100738

Yanfeng Mao , Qing Guo , Xiaomin Geng , Hongyan Zeng , Shengtang Liu , Xiuhua Yin , Zaixing Yang

{"title":"Hexagonal boron nitride nanodots inhibit cell proliferation of HUVECs and the underlying mechanism","authors":"Yanfeng Mao , Qing Guo , Xiaomin Geng , Hongyan Zeng , Shengtang Liu , Xiuhua Yin , Zaixing Yang","doi":"10.1016/j.colcom.2023.100738","DOIUrl":"https://doi.org/10.1016/j.colcom.2023.100738","url":null,"abstract":"<div>Boron nitride (BN)-based nanomaterials have immense potential in nano-biomedicine, such as drug carriers and anti-bacterial agents. However, their biocompatibility remains a crucial concern. Here, we investigated the cytotoxicity of hexagonal BN (h-BN) nanodots (BNNDs) on HUVEC cells, assessing their effects on viability, morphology, proliferation, cell cycle, genes, and protein expression. BNNDs had limited impact on HUVECs viability, even at high concentrations (200 μg/mL, 48 h). Yet, they hindered cell proliferation and caused cell cycle arrest in the S phase in a dose−/time-dependent manner. Cytotoxicity primarily resulted from disturbances in cell proliferation and DNA replication-related genes (e.g., GADD45A) and proteins (e.g., GADD45A). BNNDs also induced oxidative stress, enhancing cytotoxic effects. Therefore, cautious evaluation of long-term cytotoxicity is crucial before employing BNNDs in biological systems. Additionally, certain dye-based cytotoxicity assessment methods may not accurately reflect the cytotoxicity of BNNDs. Understanding these new cytotoxic mechanisms can aid in designing safer BN-based nano-medicines/devices.</div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"56 ","pages":"Article 100738"},"PeriodicalIF":4.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49710143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Large-scale synthesis of CISe/ZnS core-shell quantum dots and its effects on the enzymatic activity of recombinant human furin (an activator of SARS-COV-2 S1/S2 spike proteins) CISe/ZnS核壳量子点的大规模合成及其对重组人糠蛋白(S1/S2刺突蛋白激活剂)酶活性的影响

IF 4.5 3区材料科学

Colloid and Interface Science Communications Pub Date : 2023-09-01 DOI: 10.1016/j.colcom.2023.100737

Vuyelwa Ncapayi , Oladoyin Famutimi , Thabang Calvin Lebepe , Rodney Maluleke , Sam Masha , Nande Mgedle , Sundararajan Parani , Tetsuya Kodama , Isaac Olusanjo Adewale , Oluwatobi Samuel Oluwafemi

{"title":"Large-scale synthesis of CISe/ZnS core-shell quantum dots and its effects on the enzymatic activity of recombinant human furin (an activator of SARS-COV-2 S1/S2 spike proteins)","authors":"Vuyelwa Ncapayi , Oladoyin Famutimi , Thabang Calvin Lebepe , Rodney Maluleke , Sam Masha , Nande Mgedle , Sundararajan Parani , Tetsuya Kodama , Isaac Olusanjo Adewale , Oluwatobi Samuel Oluwafemi","doi":"10.1016/j.colcom.2023.100737","DOIUrl":"https://doi.org/10.1016/j.colcom.2023.100737","url":null,"abstract":"<div>We herein report, for the first time, the activity of copper indium selenide/zinc sulphide core-shell quantum dots (CISe/ZnS QDs) as an inhibitor against recombinant human furin, an enzyme that has been implicated in the aetiology of many diseases, including Covid-19. The cell viability of the as-synthesised CISe/ZnS QDs was tested against mouse colon carcinoma cells (C26), while the Furin activity was measured by hydrolysis of peptide substrate Pyr-RTKR-AMC liberating the fluorogenic 7-amino-4-methyl coumarin. The result showed that the as-synthesised stable near-infrared emitting (840 nm) CISe-ZnS QDs is biocompatible against C26 and can inhibit furin with an inhibition constant, Ki, of 15.66 μM. The IC50 was 11.29 ± 0.54 μM, while the enzymatic activity was abolished at about 23 μM of the inhibitor concentration. The results indicate the chemotherapeutic potential of CISe-ZnS QDs as an enzyme inhibitor, which may find application in managing diseases whose pathogenesis involves hyperactivity of furin.</div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"56 ","pages":"Article 100737"},"PeriodicalIF":4.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49710180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cadmium elimination from wastewater using potato peel biochar modified by ZIF-8 and magnetic nanoparticle ZIF-8改性马铃薯皮生物炭与磁性纳米颗粒去除废水中的镉

IF 4.5 3区材料科学

Colloid and Interface Science Communications Pub Date : 2023-07-01 DOI: 10.1016/j.colcom.2023.100723

Rauf Foroutan , Seyed Jamaleddin Peighambardoust , Solmaz Ghojavand , Sima Farjadfard , Bahman Ramavandi

引用次数: 13

Amine-functionalized polysilsesquioxane hollow nanospheres for pH-responsive pesticide release system with UV-shielding property 胺功能化聚硅氧烷中空纳米微球用于ph响应型紫外屏蔽农药释放系统

IF 4.5 3区材料科学

Colloid and Interface Science Communications Pub Date : 2023-07-01 DOI: 10.1016/j.colcom.2023.100726

Ye Yang , Xiaohang Lin , Shuai Liu , Chengtao Gao , Fuping Dong , Yuzhu Xiong

引用次数: 0

Flexible plasmonic nanoparticle-on-a-mirror metasurface-enabled substrates for high-quality surface-enhanced Raman spectroscopy detection 柔性等离子体纳米粒子-镜面超表面衬底用于高质量的表面增强拉曼光谱检测

IF 4.5 3区材料科学

Colloid and Interface Science Communications Pub Date : 2023-07-01 DOI: 10.1016/j.colcom.2023.100728

Pei Zeng , Dongxu Ma , Mengjie Zheng , Lei Chen , Huikang Liang , Zhiwen Shu , Yifei Fu , Meiyan Pan , Qian Zhao , Huigao Duan

{"title":"Flexible plasmonic nanoparticle-on-a-mirror metasurface-enabled substrates for high-quality surface-enhanced Raman spectroscopy detection","authors":"Pei Zeng , Dongxu Ma , Mengjie Zheng , Lei Chen , Huikang Liang , Zhiwen Shu , Yifei Fu , Meiyan Pan , Qian Zhao , Huigao Duan","doi":"10.1016/j.colcom.2023.100728","DOIUrl":"https://doi.org/10.1016/j.colcom.2023.100728","url":null,"abstract":"<div>Surface-enhanced Raman scattering (SERS) technology with the advantages of ultra-high sensitivity, non-destructive analysis, and quick measurement for molecular detection applications is receiving increasing attention. However, traditional rigid SERS substrates face challenges in in-suit conformal detection and weak structure coupling effect for real-life applications. Here we report a flexible polydimethylsiloxane (PDMS) substrate loaded with plasmonic nanoparticle-on-a-mirror (NPOM) metasurface for SERS detection that featured outstanding sensitivity, uniformity, repeatability, and excellent mechanical flexibility. The upper multilayered NPOM metasurface can be fabricated in a single-step process by ion beam sputtering of various targets. This NPOM configuration consists of dense silver nanoparticles over a silver mirror, separated by a SiO2 spacer layer, which can realize near-total power absorption and exhibits superior SERS ability. The bottom PDMS layer for support can provide excellent mechanical properties. In the test, the as-prepared NPOM/PDMS substrates show high SERS performance in detecting crystal violet and chlorpyrifos molecules. This flexible metasurface SERS substrate promises to provide an in-suit and efficient approach for trace substance detection.</div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"55 ","pages":"Article 100728"},"PeriodicalIF":4.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49731003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Substrate stiffness dominants cell gene expression via regulation of HDAC3 subcellular localization 底物硬度通过调控HDAC3亚细胞定位来支配细胞基因表达

IF 4.5 3区材料科学

Colloid and Interface Science Communications Pub Date : 2023-07-01 DOI: 10.1016/j.colcom.2023.100719

Peng Wang , Jiwen Geng , Chunyu Tan , Qiang Wei

{"title":"Substrate stiffness dominants cell gene expression via regulation of HDAC3 subcellular localization","authors":"Peng Wang , Jiwen Geng , Chunyu Tan , Qiang Wei","doi":"10.1016/j.colcom.2023.100719","DOIUrl":"https://doi.org/10.1016/j.colcom.2023.100719","url":null,"abstract":"<div>Adhesive interface stiffness is capable of modulating cellular behavior and gene expression, yet the underlying mechanobiological mechanisms remain unclear. In this study, we investigated the effects of interface stiffness on gene expression pathways by hydrogels with divergent stiffness. Our results reveal that adhesive interface stiffness affects cytoplasmic mechanotranduction as well as nuclear mechanics, and ultimately regulating the subcellular localization of HDAC3. Further investigation unfolds that HDAC3 directly affects global acetylation levels within nucleus. And HDAC3-induced acetylation changes are regulated by myosin contraction, thereby portraying downstream gene expression. Additionally, our study indicates that the interface stiffness-mediated regulation of HDAC3 nuclear-cytoplasmic redistribution is dependent on CRM1, and inhibition of CRM1 impedes the nuclear export of HDAC3. In summary, our work provides an overview of how the subcellular localization of HDAC3 can be manipulated through the regulation of cell adhesion interface stiffness, thereby altering upstream RNA polymerase II activity and gene expression.</div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"55 ","pages":"Article 100719"},"PeriodicalIF":4.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Tumor-targeted astaxanthin nanoparticles for therapeutic application in vitro 肿瘤靶向虾青素纳米颗粒的体外治疗应用

IF 4.5 3区材料科学

Colloid and Interface Science Communications Pub Date : 2023-07-01 DOI: 10.1016/j.colcom.2023.100721

Wei Xie , Shanzhi Tan , Xiyun Ren , Jinling Yu , Chen Yang , Hongquan Xie , Zihui Ma , Ying Liu , Shucai Yang

引用次数: 1

Co2P2O7@MoO3/NF composite electrocatalysts by different phosphorus sources for efficient oxygen evolution reaction and overall water splitting Co2P2O7@MoO3/NF复合电催化剂采用不同磷源进行高效析氧反应和整体水分解

IF 4.5 3区材料科学

Colloid and Interface Science Communications Pub Date : 2023-07-01 DOI: 10.1016/j.colcom.2023.100727

Tongtong Li, Wan Wan, Yali Cao, Jialing Xu, Hui Chai

{"title":"Co2P2O7@MoO3/NF composite electrocatalysts by different phosphorus sources for efficient oxygen evolution reaction and overall water splitting","authors":"Tongtong Li, Wan Wan, Yali Cao, Jialing Xu, Hui Chai","doi":"10.1016/j.colcom.2023.100727","DOIUrl":"https://doi.org/10.1016/j.colcom.2023.100727","url":null,"abstract":"<div>Electrocatalysts comprising MoO3 coated by Co2P2O7 nanocrystals were grown on a nickel foam (NF) substrate. The applicability of the nanocomposite material (Co2P2O7@MoO3/NF) as an electrode for the oxygen evolution reaction (OER) and overall water splitting was verified. The as-synthesized product showed the overpotentials of 227 and 377 mV to drive the OER at current densities of 50 and 100 mA cm−2, respectively. Furthermore, the voltage of Co2P2O7@MoO3/NF as a bifunctional overall water splitting catalyst was 1.55 V at 10 mA cm−2. Co2P2O7@MoO3/NF@NF (+)//Co2P2O7@MoO3/NF (−) can maintain >80% of its initial current density after 30 h at 15 mA cm−2. The Co2P2O7@MoO3/NF electrode also showed a low hydrogen evolution reaction overpotential of 58.7 mV at 10 mA cm−2. The excellent oxygen evolution and electrochemical water decomposition stability of the catalyst have broad application prospects.</div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"55 ","pages":"Article 100727"},"PeriodicalIF":4.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Layered FeMo2S4-packed hexagonal nitrogen-doped carbon microsheets embedded with Fe3C nanoparticles for efficient electrocatalytic oxygen evolution reaction 包覆Fe3C纳米颗粒的六方氮掺杂碳微片在高效电催化析氧反应中的应用

IF 4.5 3区材料科学

Colloid and Interface Science Communications Pub Date : 2023-07-01 DOI: 10.1016/j.colcom.2023.100729

Haochun Chen , Dafeng Zhang , Yin Wang , Shuxing Zhou , Xijun Liu , Nianpeng Li , Lei Zhang , Guangzhi Hu

{"title":"Layered FeMo2S4-packed hexagonal nitrogen-doped carbon microsheets embedded with Fe3C nanoparticles for efficient electrocatalytic oxygen evolution reaction","authors":"Haochun Chen , Dafeng Zhang , Yin Wang , Shuxing Zhou , Xijun Liu , Nianpeng Li , Lei Zhang , Guangzhi Hu","doi":"10.1016/j.colcom.2023.100729","DOIUrl":"https://doi.org/10.1016/j.colcom.2023.100729","url":null,"abstract":"<div>The design of efficient, low-cost non-noble metal oxygen evolution reaction (OER) catalysts has attracted considerable attention. Fe3C sites have excellent catalytic effects arising from their high electrical conductivity and numerous active sites. Moreover, the high–valence state of molybdenum significantly enhances the electrochemical performance of electrocatalysts. Herein, we propose a design strategy through which hexagonal Fe3C/NC microsheets can be successfully synthesised using a self-template. This strategy also demonstrates how the surfaces of hexagonal microsheets can be covered with FeMo2S4 nanosheets with active sites via hydrothermal and secondary calcination. FeMo2S4–Fe3C/NC exhibits outstanding catalytic performance, achieving a current density of 10 mA cm−2 with an overpotential of only 243 mV, Tafel slope of 32 mV dec−1, and excellent stability for up to 50 h. The number of active sites on the catalyst surface can be increased by introducing Mo and S, which effectively change the structure of the electronic environment. This study presents a new method of designing simple and efficient non-precious-metal catalysts with excellent performance for use in OER.</div>","PeriodicalId":10483,"journal":{"name":"Colloid and Interface Science Communications","volume":"55 ","pages":"Article 100729"},"PeriodicalIF":4.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49707735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0