Proceedings of the Bulgarian Academy of Sciences最新文献_第8页

Positron Trapping Rate in Some Ferroelectrics, Semiconductors and Glasses 某些铁电体、半导体和玻璃中的正电子俘获率

Proceedings of the Bulgarian Academy of Sciences Pub Date : 2023-12-21 DOI: 10.7546/crabs.2023.12.02

Stela Peneva, Troyo Troev

引用次数: 0

New Insight into Enzyme Inhibitory and Anti-proliferative Activity of Echinops ritro L. (Asteraceae) 对 Echinops ritro L.（菊科）酶抑制和抗增殖活性的新认识

Proceedings of the Bulgarian Academy of Sciences Pub Date : 2023-12-21 DOI: 10.7546/crabs.2023.12.12

V. Balabanova, D. Zheleva-Dimitrova, Y. Voynikov, Gokhan Zengin, Olivier Joubert, R. Gevrenova

{"title":"New Insight into Enzyme Inhibitory and Anti-proliferative Activity of Echinops ritro L. (Asteraceae)","authors":"V. Balabanova, D. Zheleva-Dimitrova, Y. Voynikov, Gokhan Zengin, Olivier Joubert, R. Gevrenova","doi":"10.7546/crabs.2023.12.12","DOIUrl":"https://doi.org/10.7546/crabs.2023.12.12","url":null,"abstract":"Echinops ritro L. is a perennial herbaceous plant in the tribe Cardueae, Asteraceae family, widely distributed, up to 1000 m a.s.l. In the present study, the enzyme inhibitory and anti-proliferative activity of E. ritro leaves and flowering heads extracts were assayed. Quantitative determination of 22 analytes, including eleven acylquinic and one hydroxycinnamic acids, and ten flavonoids was performed by Ultra high-performance liquid chromatography – diode array detector (UHPLC-DAD) analyses. The major compound was 1,5-dicaffeoylquinic acid, being presented at $$20.48pm 0.22$$ µg/mg in the flowering heads, while the leaves demonstrated very high levels of chlorogenic acid ($$117.29pm 14.20$$ µg/mg) and 3,5-dicaffeoylquinic acid ($$12.79pm 0.282$$ µg/mg). The flavonoids were dominated by isoquercitrin and rutin ($$3.13pm 0.033$$ and $$3.25pm 0.057$$ µg/mg, respectively) together with metoxylated aglycones nepetin, hispidulin and jaceosidin (up to 0.51 µg/mg). The leaves extract revealed prominent acetylcholinesterase ($$2.33pm 0.09$$ mg GALAE/g) and α-glucosidase inhibitory potential ($$0.37pm 0.01$$ mmol ACAE/g). Nevertheless, the flowering heads extract showed distinct butyrylcholinesterase ($$1.41pm0.35$$ mg GALAE/g), tyrosinase ($$45.66pm0.84$$ mg KAE/g), amylase ($$0.37pm0.02$$ mmol ACAE/g), and lipase ($$9.06pm1.43$$ mg OE/g) inhibitory activity. The anti-proliferative assay was completed towards THP-1 monocyte leukemic cells, where at a concentration $$>1000$$ µg/mL, a significant dose dependent reduction of cell viability was observed for the leaves extract. In conclusion, the data revealed a new insight into the taxon for its health benefit application.","PeriodicalId":104760,"journal":{"name":"Proceedings of the Bulgarian Academy of Sciences","volume":"5 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138952161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Extended Family for Intrafamilial Transmission of Helicobacter pylori Infection in Bulgarian Children 大家庭在保加利亚儿童幽门螺杆菌感染的家庭内传播中的作用

Proceedings of the Bulgarian Academy of Sciences Pub Date : 2023-11-27 DOI: 10.7546/crabs.2023.11.14

P. Hadzhiyski, M. Baycheva, Rayna Shentova-Eneva, D. Kofinova, R. Markovska, Ivan Mitov, L. Boyanova

{"title":"Role of Extended Family for Intrafamilial Transmission of Helicobacter pylori Infection in Bulgarian Children","authors":"P. Hadzhiyski, M. Baycheva, Rayna Shentova-Eneva, D. Kofinova, R. Markovska, Ivan Mitov, L. Boyanova","doi":"10.7546/crabs.2023.11.14","DOIUrl":"https://doi.org/10.7546/crabs.2023.11.14","url":null,"abstract":"Helicobacter pylori infection is one of the most common chronic bacterial infections worldwide. The infection is usually acquired during the first years of childhood and transmission from infected mother is considered an important epidemiological factor. The aim of this study was to assess the H. pylori positivity in Bulgarian symptomatic children in association with the presence or absence of family anamnesis of gastroduodenal diseases among their parents, siblings and grandparents. H. pylori infection was evaluated in 362 children in two groups: 181 children with family anamnesis of gastroduodenal diseases and 181 children without family anamnesis. All patients underwent esophagogastroduodenoscopy and gastric biopsy samples for microbiological examination for H. pylori were taken. H. pylori infection among children with family history of gastroduodenal diseases was significantly more frequent (69.1%) compared with the group of patients without a family anamnesis (21.0%, p <0.0001). In addition to the significance of the infected parents (69.4%) and siblings (52.0%), infected grandparents were also associated with high prevalence of the infection (77.8%, 21/27 cases) in the children. In conclusion, H. pylori infection among children with family history of gastroduodenal disease was 3.3-fold higher than that in the group without family anamnesis. The significance of the grandparents in the extended family households should be considered.","PeriodicalId":104760,"journal":{"name":"Proceedings of the Bulgarian Academy of Sciences","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139229558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Noninvasive Evaluation of Central Haemodynamic Parameters 中心血流动力学参数的无创评估

Proceedings of the Bulgarian Academy of Sciences Pub Date : 2023-11-27 DOI: 10.7546/crabs.2023.11.16

Rene Mileva-Popova, Nina Y. Belova

{"title":"Noninvasive Evaluation of Central Haemodynamic Parameters","authors":"Rene Mileva-Popova, Nina Y. Belova","doi":"10.7546/crabs.2023.11.16","DOIUrl":"https://doi.org/10.7546/crabs.2023.11.16","url":null,"abstract":"Ageing is one of the relevant cardiovascular risk factors. Non-invasive assessment of cardiac function is an important approach in preventive medicine. The aim of our study was to evaluate the effect of age and gender on central haemodynamics. Seventy-six clinically healthy individuals were divided into four groups according to their age and gender. Applanation tonometry was applied using Sphygmocor device (AtCor, Australia). Pulse wave analysis was utilized for non-invasive assessment of central pressures (systolic, diastolic, mean, pulse, augmentation and end-systolic). Several important derivative indices such as augmentation index AIx75 $$(frac{rm Augmentation pressure}{rm Pulse pressure}times 100$$, corrected for heart rate 75 beats/minute), arterial elastance (Ea,$$frac{rm End - systolic pressure}{rm Stroke volume})$$ and wasted effort (Ew) were computed. Ew is the ventricular force that is generated to overcome the late systolic peak and does not contribute to an increased stroke volume. Arterial stiffening was confirmed by the significantly higher central systolic and pulse pressures, AIx75 and arterial elastance in the middle-aged groups ($$P<0.01$$). Those alterations were most pronounced in middle-aged females in support to the concept for a postmenopausal effect of female gender beyond ageing. We have shown a positive correlation between Ew and Ea valid only for the middle-aged individuals ($$R=0.70$$, $$P<0.001$$) that coincided with similar correlation between Ea and AIx75 for the same age groups ($$R=0.53$$, $$P<0.001$$). Our supposition is that arterial stiffening contributes to the elevation of the `pulsatile' afterload thus impairing vascular/ventricular coupling and increasing myocardial load and oxygen demands. In conclusion, applanation tonometry and PWA provide reliable measures of central haemodynamics and myocardial afterload.","PeriodicalId":104760,"journal":{"name":"Proceedings of the Bulgarian Academy of Sciences","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139230529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Briot–Bouquet Subordination Properties for Analytic Functions Involving Choi–Saigo–Srivastava Integral Operator 涉及 Choi-Saigo-Srivastava 积分算子的解析函数的 Briot-Bouquet 从属性

Proceedings of the Bulgarian Academy of Sciences Pub Date : 2023-11-27 DOI: 10.7546/crabs.2023.11.02

Hatice Uçar, A. Çetinkaya

引用次数: 0

New Data on the Expression of the Early Eocene Hyperthermals in Northern Bulgaria: Riben Section Revisited 关于保加利亚北部早始新世超热岩表现的新数据：重新审视里本段

Proceedings of the Bulgarian Academy of Sciences Pub Date : 2023-11-27 DOI: 10.7546/crabs.2023.11.06

K. Stoykova, E. Koleva-Rekalova, Torsten Vennemann, M. Ivanov

{"title":"New Data on the Expression of the Early Eocene Hyperthermals in Northern Bulgaria: Riben Section Revisited","authors":"K. Stoykova, E. Koleva-Rekalova, Torsten Vennemann, M. Ivanov","doi":"10.7546/crabs.2023.11.06","DOIUrl":"https://doi.org/10.7546/crabs.2023.11.06","url":null,"abstract":"We present new lithologic, nannofossil biostratigraphic and benthic carbon and oxygen isotope records for a marly-rich, 11 m thick Paleocene-Eocene section, now exposed at an old quarry at Riben Village, northern Bulgaria. The occurrence of NP9, NP10 and NP11 nannofossil zones is evidenced by detailed high-resolution nannofossil biostratigraphy. The carbon dissolution interval is marked by the abrupt drop of CaCO3 content and deposition of a clay interval at the onset of the Paleocene-Eocene Thermal Maximum (PETM). Stable isotope analyses of δ13C and δ18O were performed on benthic-foraminiferal tests. An unusual two-fold carbon isotope excursion (CIE) in the PETM interval is documented (total negative shift of 2.89‰). Moreover, three paired negative excursions: two in the Paleocene within the PETM interval, upper NP9 zone, and one within the early Eocene, NP11 zone are identified. The most prominent negative carbon isotope excursion (4.90‰ negative shift) is related with ETM3 (or “X” event), 52.84 Ma ago. Integration of nannofossil biostratigraphy, benthic stable isotope data sets and lithology unravel two separate early Eocene hyperthermal events: the PETM (= ETM1) and the ETM3 (= “X” event), recorded at Riben section.","PeriodicalId":104760,"journal":{"name":"Proceedings of the Bulgarian Academy of Sciences","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139229466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High Stability Dual Beam Interferometer Sensor for Non-contact Photoacoustic Imaging 用于非接触式光声成像的高稳定性双光束干涉仪传感器

Proceedings of the Bulgarian Academy of Sciences Pub Date : 2023-11-27 DOI: 10.7546/crabs.2023.11.10

Xin Zhao, Xiaoya Wei, Huilin Xu, Bo Yu, Peng Hu

{"title":"High Stability Dual Beam Interferometer Sensor for Non-contact Photoacoustic Imaging","authors":"Xin Zhao, Xiaoya Wei, Huilin Xu, Bo Yu, Peng Hu","doi":"10.7546/crabs.2023.11.10","DOIUrl":"https://doi.org/10.7546/crabs.2023.11.10","url":null,"abstract":"As a non-contact photoacoustic sensor, the reflector of one arm of dual beam interferometer sensor is usually composed of the upper surface of the ultrasonic coupling liquid coated on the surface of the sample. The vibration of the outside and the scanning motor cause the liquid level to shake, causing the reflected probe light path to deviate from the incident light path, which then reduces the detection stability of the sensor. In view of the above problems, a novel high stability dual beam interferometer sensor is introduced in this paper, in which the reflected probe light is derived from the original optical path by using the combination of PBS and quarter wave plate, and the reflected probe light is coupled into 50/50 beam splitting fibre by using aspheric mirror group. The influence of the radius and focal length of each aspheric mirror and the numerical aperture of the optical fibre on the detection stability of the sensor is theoretically analyzed. The results show that the structural design greatly reduces the effect of the vibration of the outside and the scanning motor on the detection stability of the sensor, and provides a theoretical basis for the development and performance optimization of the sensor.","PeriodicalId":104760,"journal":{"name":"Proceedings of the Bulgarian Academy of Sciences","volume":"176 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139230974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of Natural Condition in Urban Landscapes of Plain Areas Based on GIS 基于地理信息系统的平原地区城市景观自然状况调查

Proceedings of the Bulgarian Academy of Sciences Pub Date : 2023-11-27 DOI: 10.7546/crabs.2023.11.05

Shahnaz Amanova, G. Hajiyeva

引用次数: 0

In Vitro Cultivation of Saffron (Crocus sativus L.) and Assessment of Genetic Homogeneity Using iPBS Markers 藏红花（Crocus sativus L.）的体外培养和 iPBS 标记的遗传同质性评估

Proceedings of the Bulgarian Academy of Sciences Pub Date : 2023-11-27 DOI: 10.7546/crabs.2023.11.04.

M. Petrova, Georgi Bonchev, Lyudmila Dimitrova, M. Dimitrova, Roumiana Vassilevska-Ivanova

引用次数: 0

Antibacterial Potential of Ethanol Extract of Marigold (Tagetes erecta L.) 万寿菊乙醇提取物的抗菌潜力

Proceedings of the Bulgarian Academy of Sciences Pub Date : 2023-11-27 DOI: 10.7546/crabs.2023.11.03

S. Vergiev, Denis Niyazi

引用次数: 0