Clinical, Cosmetic and Investigational Dentistry最新文献

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The Use of Salivary and Gingival Crevicular Fluid Biomarkers in Predicting Orthodontic Treatment Response. 唾液和牙龈沟液生物标志物在预测正畸治疗反应中的应用。
IF 1.8
Clinical, Cosmetic and Investigational Dentistry Pub Date : 2025-11-05 eCollection Date: 2025-01-01 DOI: 10.2147/CCIDE.S552825
Suhad Mohammed Ali Sadeq, Nadia Al Ansari, Zena Kamel Kadhem, Hashim Mueen Hussein
{"title":"The Use of Salivary and Gingival Crevicular Fluid Biomarkers in Predicting Orthodontic Treatment Response.","authors":"Suhad Mohammed Ali Sadeq, Nadia Al Ansari, Zena Kamel Kadhem, Hashim Mueen Hussein","doi":"10.2147/CCIDE.S552825","DOIUrl":"10.2147/CCIDE.S552825","url":null,"abstract":"<p><strong>Background: </strong>Oral fluids are considered a promising diagnostic method to demonstrate the biomarkers for many oral inflammatory and physiological conditions. Orthodontic treatment is associated with changes in bone remodeling and tissue inflammatory biomarkers.</p><p><strong>Objective: </strong>The research assessed the effectiveness of salivary biomarkers, which include cytokines, MMPs, and bone turnover markers, in describing the unwanted oral and dental pathological outcomes and to provide clinical precision in following orthodontic treatment in patients who were treated with the fixed orthodontic appliance.</p><p><strong>Materials and methods: </strong>Blended longitudinal and Cross-sectional study: one hundred patients were followed up throughout one year after enrollment, aged between twelve and eighteen years old. Salivary and Gingival Crevicular Fluid biomarker concentrations were assayed at the beginning of the study and at multiple time points regarding the treatment. Interleukin IL-1β, Tumor Necrosis Factor TNF-α, Matrix Metalloproteinases MMP8 and MMP9, and bone turnover markers (RANKL/OPG) were the biomarkers included.</p><p><strong>Results: </strong>The mean concentrations of both cytokines were 1.55-fold higher in the first month. MMP-8 and MMP-9 concentrations increased between the third and sixth months from baseline in 50% and 45% respectively. Patients with high cytokine MMP levels resulted in tooth movement, with 15% enhanced compared to the control group, and finished treatment quicker. There were disparities in cytokine levels whereby, generally, males had slightly elevated levels of cytokines compared to the female patients, although this did not influence treatment efficacy. The RANKL/OPG ratio is elevated during the first three months in the active phase of bone remodeling.</p><p><strong>Conclusion: </strong>The reliability of salivary and GCF biomarkers as predictors. Thus, cytokines and MMPs, and the RANKL/OPG ratio, being biomarkers, identify response to a specific treatment and also in orthodontic management, including avoiding root resorption, unwanted bone remodeling, and oral pathologies.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"17 ","pages":"499-513"},"PeriodicalIF":1.8,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12598585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145494818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Mouthwashes on the Surface Roughness of Stainless Steel Orthodontic Brackets. 漱口水对不锈钢正畸托槽表面粗糙度的影响。
IF 1.8
Clinical, Cosmetic and Investigational Dentistry Pub Date : 2025-10-23 eCollection Date: 2025-01-01 DOI: 10.2147/CCIDE.S552872
Khalid A Abalkhail, Raghad K Alhassoun, Farraj Albalawi, Suliman Alsaeed
{"title":"Effect of Mouthwashes on the Surface Roughness of Stainless Steel Orthodontic Brackets.","authors":"Khalid A Abalkhail, Raghad K Alhassoun, Farraj Albalawi, Suliman Alsaeed","doi":"10.2147/CCIDE.S552872","DOIUrl":"10.2147/CCIDE.S552872","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the effect of three oral mouthwashes on the surface roughness of stainless steel orthodontic brackets from two commercial brands, ORMCO and 3M Unitek.</p><p><strong>Methods: </strong>A total of sixty upper bicuspid stainless steel brackets were used, divided equally between the two brands: 30 ORMCO brackets and 30 3M Unitek brackets. Each brand group was further subdivided into three subgroups of ten brackets, with each subgroup immersed in one of three oral rinses: water and salt solution, LISTERINE™ sodium fluoride mouthwash and OREX™ sodium fluoride mouthwash. Surface roughness was measured using an optical profilometer after 90 minutes of immersion and again after seven days, to assess the potential influence of exposure duration on surface roughness.</p><p><strong>Results: </strong>One-way ANOVA revealed no statistically significant differences in surface roughness among most groups (p ≥ 0.05). The highest surface roughness was observed in the ORMCO brackets immersed in OREX fluoridated mouthwash for seven days (mean = 0.9169 µm). The lowest was in the 3M Unitek group immersed in the water and salt solution for 90 minutes (mean = 0.9130 µm). Although the roughness values showed a statistically significant difference, the magnitude of the difference was minimal (0.0039 µm) and considered clinically insignificant.</p><p><strong>Conclusion: </strong>This study found that sodium fluoride mouthwashes resulted in slightly higher surface roughness of stainless steel orthodontic brackets compared to water and salt rinse. However, the differences are not clinically relevant and will not impact plaque accumulation or bracket function.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"17 ","pages":"491-498"},"PeriodicalIF":1.8,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12558085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145387506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns of Mandibular Third Molar Impactions and Its Association with Carious Lesions and Periodontal Defects: A Retrospective Cross-Sectional Study. 下颌第三磨牙嵌塞模式及其与龋病和牙周缺损的关系:一项回顾性横断面研究。
IF 1.8
Clinical, Cosmetic and Investigational Dentistry Pub Date : 2025-10-05 eCollection Date: 2025-01-01 DOI: 10.2147/CCIDE.S559569
Shahad B Alsharif, Majd B Alsharif
{"title":"Patterns of Mandibular Third Molar Impactions and Its Association with Carious Lesions and Periodontal Defects: A Retrospective Cross-Sectional Study.","authors":"Shahad B Alsharif, Majd B Alsharif","doi":"10.2147/CCIDE.S559569","DOIUrl":"10.2147/CCIDE.S559569","url":null,"abstract":"<p><strong>Purpose: </strong>Clinical consensus on prophylactic extraction of impacted mandibular third molars is still debated. This study aims to explore the impaction patterns of mandibular third molars and their associated effects on the adjacent second molars within a Saudi population, thereby providing some clinical insights for prophylactic extraction.</p><p><strong>Methods: </strong>This retrospective cross-sectional study evaluated 1700 orthopantomograms of Saudi patients, obtained from the dental hospital database at King Abdulaziz University, Jeddah, Saudi Arabia, from August 2024 to June 2025, with convenience sampling. Mandibular third molar impaction patterns were assessed according to Winter's classification, along with their association with pathological conditions, including carious lesions and periodontal defects affecting the adjacent mandibular second molars.</p><p><strong>Results: </strong>681 impacted mandibular third molars were identified and analyzed. The prevalence of these impactions was higher in females (54.2%) than in males (45.8%) (p < 0.05). Mesioangular impaction pattern was the most frequently detected, followed by horizontal. A significant association was observed between gender and the impaction patterns (p < 0.001), with the inverted and buccolingual impaction patterns predominantly observed in males, accounting for 100% and 90.0% of the impactions, respectively. The prevalence of carious lesions and periodontal defects was 23.9% and 66.9%, respectively. The two most frequent impaction patterns, horizontal and mesioangular, were significantly associated with these pathological conditions (p < 0.001).</p><p><strong>Conclusion: </strong>Prophylactic extraction of impacted mandibular third molars, particularly those exhibiting mesioangular and horizontal impaction patterns, should be considered to prevent the deleterious consequences of their retention. However, this recommendation is specific to the population inspected. Further studies focusing on diverse populations are encouraged to acquire evidence-based, population-specific recommendations to support broader clinical applicability.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"17 ","pages":"481-490"},"PeriodicalIF":1.8,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145279110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibacterial Effectiveness and Periodontal Actions of Sugar-Free Chewing Gums Derived From Alcohol or Vegetables in Patients with Fixed Orthodontic Treatment: A Systematic Review. 固定正畸治疗患者无糖酒精或蔬菜口香糖的抗菌效果和牙周作用:一项系统综述。
IF 1.8
Clinical, Cosmetic and Investigational Dentistry Pub Date : 2025-10-03 eCollection Date: 2025-01-01 DOI: 10.2147/CCIDE.S530760
Miriam Lima-Illescas, María Augusta Lara-Velecela, Katherine Cuenca-León, Edisson Mauricio Pacheco-Quito
{"title":"Antibacterial Effectiveness and Periodontal Actions of Sugar-Free Chewing Gums Derived From Alcohol or Vegetables in Patients with Fixed Orthodontic Treatment: A Systematic Review.","authors":"Miriam Lima-Illescas, María Augusta Lara-Velecela, Katherine Cuenca-León, Edisson Mauricio Pacheco-Quito","doi":"10.2147/CCIDE.S530760","DOIUrl":"10.2147/CCIDE.S530760","url":null,"abstract":"<p><strong>Aim: </strong>In patients with fixed orthodontic appliances, the effectiveness of mechanical cleaning is compromised due to difficulties in accessing all areas of the mouth.</p><p><strong>Purpose: </strong>Aimed to evaluate the antimicrobial effectiveness and periodontal actions of sugar-free chewing gums in patients with fixed orthodontics through a systematic review of randomized clinical trials.</p><p><strong>Materials and methods: </strong>A bibliographic search was conducted in digital databases for articles published up to 2024 in accordance with the PICO question. This review followed the PRISMA methodology and was registered in PROSPERO (CRD42023444472), while the Cochrane RoB 2 tool used to assess the risk of bias and GRADE employed to evaluate the certainty of evidence for each outcome.</p><p><strong>Results: </strong>Five studies were included. A significant reduction <i>Streptococcus mutans</i> in saliva was observed in two studies (-17%-33% saliva, -20%-29% dental plaque, p<0.05), with xylitol gum and it's mixture with sorbitol exerting the best effect after one month of consumption (GRADE high). An effective decrease in the plaque index was observed in two studies of xylitol gum (-43% -47%, p<0.05) after one month of consumption, as well as studies of essential oil gum (10 days) and sorbitol gum (three months) (GRADE low). Chlorhexidine, sorbitol, and essential oil gums effectively reduce gingival bleeding, and xylitol gum increases the salivary pH, more than 50% presented a high risk of bias, and less than 25% were at low risk of bias (GRADE low).</p><p><strong>Conclusion: </strong>The different types of chewing gum significantly improved the oral health of patients with fixed orthodontics, the quality of evidence suggests that chewing gums could decrease the level of SM in saliva (4:1 xylitol and sorbitol mix or xylitol). However, the heterogeneity of the studies limits the generalization to other outcomes which highlights the need for larger and longer clinical trials to confirm their efficacy.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"17 ","pages":"463-480"},"PeriodicalIF":1.8,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145250040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiomorphometric Analysis of the Greater Palatine Canal and the Pterygopalatine Fossa Using Cone Beam Computed Tomography: A Retrospective Study. 锥形束计算机断层扫描对大腭管和翼腭窝的放射形态分析:一项回顾性研究。
IF 1.8
Clinical, Cosmetic and Investigational Dentistry Pub Date : 2025-10-02 eCollection Date: 2025-01-01 DOI: 10.2147/CCIDE.S546706
Sushant Pawar, Yogesh Chhaparwal, Vathsala Patil, Kalyana Chakravarthy Pentapati, Shubha Chhaparwal, Deepak Kumar Singhal, Nayana Prabhu, Disha Prabhu
{"title":"Radiomorphometric Analysis of the Greater Palatine Canal and the Pterygopalatine Fossa Using Cone Beam Computed Tomography: A Retrospective Study.","authors":"Sushant Pawar, Yogesh Chhaparwal, Vathsala Patil, Kalyana Chakravarthy Pentapati, Shubha Chhaparwal, Deepak Kumar Singhal, Nayana Prabhu, Disha Prabhu","doi":"10.2147/CCIDE.S546706","DOIUrl":"10.2147/CCIDE.S546706","url":null,"abstract":"<p><strong>Background & objectives: </strong>The Greater Palatine Foramen (GPF), is a vital anatomical landmark for palatal nerve blocks. Hence imaging of this structure to understand its anatomy is important. Our study aimed to explore the radiomorphometric parameters of the greater palatine canal and pterygopalatine fossa using CBCT images in different age groups and gender.</p><p><strong>Subjects materials and methods: </strong>100 CBCT images showing both right and left maxillary sinus region were analysed for length of the greater palatine canal, the upper and lower opening diameters, and the intra-canal curvature. The recorded values were statistically analysed.</p><p><strong>Results: </strong>The right greater palatine canal length was significantly shorter in individuals >25 years (Mean = 31.72 mm, SD = 4.30 mm, p-value = 0.021). The left upper opening diameter increased significantly with age (Mean = 5.90 mm, SD = 1.47 mm, p-value = 0.006). Males exhibited longer canals (Avg. length mean = 33.23 mm, SD = 4.19 mm, p-value = 0.095). And larger lower opening diameters (Avg. mean = 5.69 mm, SD = 1.18 mm, p-value = 0.073) than females. Canal curvature was predominantly curved across both the age groups, but age group 18-25 years showed a significantly higher prevalence of curved canals on both sides.</p><p><strong>Conclusion: </strong>The present study showed significant variations in the morphology of the greater palatine foramen and canal curvature with respect to age and sex. Variations in GPC length, diameter, and curvature can influence the success of palatal nerve blocks, that reduce the risk of injury to the greater palatine nerve. Recognizing these differences through preoperative CBCT enables accurate anesthesia delivery, safer flap design, and precise osteotomy planning.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"17 ","pages":"445-454"},"PeriodicalIF":1.8,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral Health Status in Moroccan Hemodialysis Patients. 摩洛哥血液透析患者的口腔健康状况
IF 1.8
Clinical, Cosmetic and Investigational Dentistry Pub Date : 2025-09-30 eCollection Date: 2025-01-01 DOI: 10.2147/CCIDE.S540447
Soukaina Rouijel, Sabrine Tament, Fatima Ezzahra Zidane, Majid Sakout
{"title":"Oral Health Status in Moroccan Hemodialysis Patients.","authors":"Soukaina Rouijel, Sabrine Tament, Fatima Ezzahra Zidane, Majid Sakout","doi":"10.2147/CCIDE.S540447","DOIUrl":"10.2147/CCIDE.S540447","url":null,"abstract":"<p><strong>Purpose: </strong>End-stage chronic kidney disease (CKD) and its treatment by hemodialysis represent a public health issue especially in Morocco. This study aimed to assess the impact of chronic renal failure on oral health in patients undergoing renal dialysis.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted among patients undergoing dialysis. The variables recorded were DMFT (Decayed, Missing, and Filled Teeth) index and pH salivary. The correlation between oral health and the duration of dialysis was assessed.</p><p><strong>Results: </strong>A total of 46 adult hemodialysis was evaluated, among them 52.2% were males, the mean age was 58.72 ± 12.4 years. All the patients in the sample underwent three dialysis sessions per week. Half of the patients brushed their teeth once a day. The average DMFT index was 15.41 ± 6.04. Xerostomia was noted in 84.8% of the sample. This health situation analysis showed that dental care of the dialysis patients was not favorable, highlighting a great need for dental treatment.</p><p><strong>Conclusion: </strong>CKD cases should be made aware of the oral problems and their potential effect on overall health. A multidisciplinary approach with the involvement of different specialties is recommended.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"17 ","pages":"455-461"},"PeriodicalIF":1.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mouth Breathing and Its Impact on Sleep Breathing Disorders in Children: A Cross-Sectional Study in Bandung, Indonesia. 口腔呼吸及其对儿童睡眠呼吸障碍的影响:印度尼西亚万隆的一项横断面研究。
IF 1.8
Clinical, Cosmetic and Investigational Dentistry Pub Date : 2025-09-01 eCollection Date: 2025-01-01 DOI: 10.2147/CCIDE.S536188
Risti Saptarini Primarti, Aliannisya Fatma, Claudia Nur Rizky Jayanti, Iwan Ahmad Musnamirwan, Arlette Suzy Setiawan
{"title":"Mouth Breathing and Its Impact on Sleep Breathing Disorders in Children: A Cross-Sectional Study in Bandung, Indonesia.","authors":"Risti Saptarini Primarti, Aliannisya Fatma, Claudia Nur Rizky Jayanti, Iwan Ahmad Musnamirwan, Arlette Suzy Setiawan","doi":"10.2147/CCIDE.S536188","DOIUrl":"10.2147/CCIDE.S536188","url":null,"abstract":"<p><strong>Purpose: </strong>Mouth breathing is an associated or characteristic feature of sleep-disordered breathing (SDB), not a direct cause. This study aims to investigate whether mouth-breathing children in Indonesia have a higher risk of SDB, as assessed by the Pediatric Sleep Questionnaire (PSQ) questionnaire.</p><p><strong>Patients and methods: </strong>A cross-sectional study was conducted in three public elementary schools in Bandung (SDN 001 Merdeka, SDN 062 Ciujung, and SDN 054 Tikukur), involving 343 children aged 8-9 years (193 boys, 150 girls). Clinical examinations were performed to identify mouth breathing habits, followed by administration of the PSQ questionnaire completed by parents. Prior to questionnaire completion, parents received standardized guidance via standardized online briefing sessions.</p><p><strong>Results: </strong>Mouth breathing was observed in 95 children (27.7%). PSQ scores were significantly higher in mouth breathers compared to non-mouth breathers (mean: 25.45% vs 7.93%; median: 19.05% vs 4.54%; range: 4.54-58.82 vs 0.0-45.46; p < 0.001). Furthermore, 41.1% of mouth-breathing children were identified as having SDB, in contrast to 9.7% of non-mouth breathers. The relative risk (RR) for SDB in mouth breathers was 4.24 (95% CI: 2.70-6.65; p < 0.001).</p><p><strong>Conclusion: </strong>Mouth breathing in school-aged children is significantly associated with a higher risk of developing sleep-disordered breathing. These findings highlight the importance of early screening and timely intervention to prevent adverse health outcomes linked to SDB.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"17 ","pages":"435-444"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physicochemical and Antimicrobial Properties of Bioceramic Sealer Enhanced with Silver Nanoparticles: An in vitro Evaluation. 纳米银增强生物陶瓷封口剂的理化和抗菌性能:体外评价。
IF 1.8
Clinical, Cosmetic and Investigational Dentistry Pub Date : 2025-08-31 eCollection Date: 2025-01-01 DOI: 10.2147/CCIDE.S534254
Karam Ahmed, Nik Rozainah Nik Abdul Ghani, Okba Mahmoud
{"title":"Physicochemical and Antimicrobial Properties of Bioceramic Sealer Enhanced with Silver Nanoparticles: An in vitro Evaluation.","authors":"Karam Ahmed, Nik Rozainah Nik Abdul Ghani, Okba Mahmoud","doi":"10.2147/CCIDE.S534254","DOIUrl":"10.2147/CCIDE.S534254","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to determine the impact of different nanoparticle concentrations with endodontic bioceramic sealer. It was assessed the combination by analyzing the correlation between the degree of conversion (DC) and antibacterial efficacy. And assess the penetration depth into the lateral canals.</p><p><strong>Materials and methods: </strong>The AH Plus bioceramic sealers were mixed with silver nanoparticles (Ag) at different concentrations (2.5%, 5%, 10%). The antibacterial efficacy against Enterococcus faecalis was evaluated utilizing the direct contact test (DCT) at multiple time intervals (immediately, 30 minutes, 1 day, 2 days, and 7 days). The conversion degree was evaluated by FTIR. The penetration depth was evaluated using X-ray examination.</p><p><strong>Results: </strong>The antibacterial activity increased with higher concentrations of nanoparticles, with silver nanoparticles demonstrating a pronounced effect on E. faecalis. The conversion degree increased with high quantities of silver nanoparticles. Positive, strong relation between the degree of conversion and antimicrobial activity. The penetration depth decreased as nanoparticle concentration increased. A statistically significant difference was seen between the antibacterial activity values and the degree of conversion at different time intervals (P = 0.05).</p><p><strong>Conclusion: </strong>The highest nanoparticles concentration (10%) has the greatest effect on the antibacterial activity and degree of conversion, the highest nanoparticles concentration decreased the penetration depth into the lateral canals.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"17 ","pages":"423-434"},"PeriodicalIF":1.8,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and Esthetic Outcomes of Anodized Titanium Abutments: A Systematic Review of Randomized Controlled Trials. 阳极氧化钛基台的临床和美学效果:随机对照试验的系统评价。
IF 1.8
Clinical, Cosmetic and Investigational Dentistry Pub Date : 2025-08-29 eCollection Date: 2025-01-01 DOI: 10.2147/CCIDE.S535430
Aldilla Miranda, Ira Komara, Arief Cahyanto, Cortino Sukotjo, Agus Susanto
{"title":"Clinical and Esthetic Outcomes of Anodized Titanium Abutments: A Systematic Review of Randomized Controlled Trials.","authors":"Aldilla Miranda, Ira Komara, Arief Cahyanto, Cortino Sukotjo, Agus Susanto","doi":"10.2147/CCIDE.S535430","DOIUrl":"10.2147/CCIDE.S535430","url":null,"abstract":"<p><p>Titanium is widely used for dental implant abutments due to its mechanical strength, biocompatibility, and corrosion resistance; however, its gray coloration can compromise esthetic outcomes, particularly in patients with thin or translucent gingival biotypes. Anodization, a surface modification technique altering the titanium oxide layer, has been proposed to improve soft tissue aesthetics by producing abutments with warmer tones (eg, pink or gold) that harmonize with the surrounding gingiva. This systematic review aimed to evaluate the clinical and aesthetic outcomes of anodized titanium abutments compared to non-anodized titanium and other materials, with a focus on peri-implant soft tissue health and visual integration. Following PRISMA 2020 guidelines, a comprehensive search was conducted in Scopus, PubMed, and ScienceDirect for Randomized Controlled Trials (RCTs) published between 2013 and 2024. Eligibility followed the PICOS framework. Nine RCTs with parallel or split-mouth designs and follow-ups from six weeks to two years were included. Esthetic outcomes were assessed using CIELab spectrophotometry and the Pink Esthetic Score (PES), while clinical parameters included mucosal recession, probing depth, plaque accumulation, gingival inflammation, and bleeding on probing. Study quality was appraised using the Cochrane Risk of Bias 2.0 tool. Anodized titanium abutments demonstrated enhanced aesthetic outcomes, especially in thin gingival biotypes, by improving colour harmony and reducing grayish shine-through. Pink-anodized abutments also showed better soft tissue integration compared to controls. However, clinical improvements such as reductions in inflammation, plaque, or recession were modest, inconsistent, and often statistically insignificant across studies. While anodization appears safe and beneficial for visual outcomes, its functional clinical advantages remain uncertain. These findings call for cautious interpretation and highlight the need for further well-powered, standardized long-term RCTs to validate the broader clinical relevance.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"17 ","pages":"405-421"},"PeriodicalIF":1.8,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12408774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison Between Game-Based Learning and Traditional Learning Methods in Traumatic Dental Management Among Dental Interns at KAUFD. KAUFD牙科实习生创伤性牙科管理中游戏学习与传统学习方法的比较
IF 1.8
Clinical, Cosmetic and Investigational Dentistry Pub Date : 2025-08-25 eCollection Date: 2025-01-01 DOI: 10.2147/CCIDE.S538541
Faisal M Dardeer, Reem M Areesh, Aasaiel Ahmed Alnafisi, Ibtesam Alzain, Basil M Andijani, Shahad N Abudawood, Abeer M Abdullah, Abdalrahman M Ainousa, Mohammed Alulaiyan
{"title":"Comparison Between Game-Based Learning and Traditional Learning Methods in Traumatic Dental Management Among Dental Interns at KAUFD.","authors":"Faisal M Dardeer, Reem M Areesh, Aasaiel Ahmed Alnafisi, Ibtesam Alzain, Basil M Andijani, Shahad N Abudawood, Abeer M Abdullah, Abdalrahman M Ainousa, Mohammed Alulaiyan","doi":"10.2147/CCIDE.S538541","DOIUrl":"10.2147/CCIDE.S538541","url":null,"abstract":"<p><strong>Introduction: </strong>Many dental students lack sufficient knowledge to manage dental trauma. Traditional lectures usually involve one-way communication from the instructor to the students. Game-based learning strategies can increase student engagement, offer hands-on experiences, and promote a deeper interest in learning.</p><p><strong>Objective: </strong>To compare the knowledge and satisfaction of dental interns participating in game-based learning versus traditional learning method on traumatic dental management at KAUFD.</p><p><strong>Methods: </strong>An experimental study conducted at the Faculty of Dentistry at King Abdulaziz University involved a sample size of 88 dental interns. The interns were divided into a game-based learning group (game group) and a traditional lecture group (lecture group). The game group participated in a game-based learning session, engaging in an educational game focused on managing permanent teeth trauma. Meanwhile, the lecture group attended a traditional lecture covering the same topic. Both groups took part in pre- and post-quizzes before and after the sessions and completed a satisfaction survey distributed after the sessions.</p><p><strong>Results: </strong>Both lecture formats significantly enhanced knowledge retention. Post-intervention scores were comparable between the groups (p = 0.393), The mean post-intervention correct score for the lecture group was 12.72 (SD = 1.33; 95% CI: 12.32-13.13), while the mean score for the game group was 12.62 (SD = 1.56; 95% CI: 12.15-13.09). showing no significant difference in score improvements (p = 0.315). The post-intervention satisfaction survey indicated positive responses in both groups, with no significant differences in satisfaction levels.</p><p><strong>Conclusion: </strong>The findings indicate that both game-based learning and traditional lectures are equally effective in enhancing knowledge and ensuring high satisfaction among dental interns. Given the similar results, it is recommended to incorporate both approaches in educational settings. Future research should investigate the impact of new content and more complex game designs to understand their potential benefits better.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"17 ","pages":"381-390"},"PeriodicalIF":1.8,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12396231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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